Having been marketed to millions as a weight-loss solution, the Atkins diet is now presented as a means of preventing type 2 diabetes, a disease whose rates are skyrocketing, thanks to the prevalence of risk factors such as obesity and high lipid and bloo

Living with diabetes is a balancing act. Monitoring blood glucose, food intake, and medication is complicated, so individuals with diabetes need to understand their condition and how best to control it. "The Johns Hopkins Guide to Diabetes" is a comprehe

Emphasizing a team approach that includes the practicing podiatrist, endocrinologist, diabetologist, vascular surgeon, orthopedist, and infectious disease specialist, The High Risk Diabetic Foot provides a thorough and detailed resource on the management of complex diabetic foot problems. This comprehensive text is an essential tool that will enable physicians to reduce infections and amputations through careful examination, diagnosis, treatment, and prevention. Key features in The High Risk Diabetic Foot include: A full section devoted to the prevention of amputation High-quality images for accurate diagnosis Chapters organized by epidemiology, classification and staging, diagnosis, special studies, and medical and surgical management Summary tables and flow charts for quick reference A discussion of the co-morbidities associated with diabetic foot pathology, including sensory neuropathy, painful neuropathy, peripheral vascular disease, food wounds, and more Identification of the level of medical evidence associated with treatment recommendations

In a field saturated with complex and conflicting information, this exciting new book covers information about nutrition before, during and after pregnancy in a clear and user friendly style. The author addresses all the major aspects of the subject, moving from fertility and preparing the body for pregnancy, through to nutrient metabolism, diet and pregnancy outcome, weight gain, special needs, and postpartum changes and nutrition.

This guide's evidence based approach will appeal to nutritionists and dietitians, and to many other health professionals who work with women in their childbearing years, including midwives, nurses and family practioners. Each chapter includes a useful set of appendices covering dietary requirements, nutritional composition of key foods and weight gain guidelines, as well as application in practice sections and a summary of key points.

Traditionally, nutrition textbooks have divided human nutrition into basic science, public health and clinical nutrition, however in this exciting new textbook, Professor Simon Langley–Evans spans these divisions, bringing together the full range of disciplines into one accessible book through the lifespan approach.

 From basic nutrition principles to the latest nutrition therapies for common diseases, Williams' Essentials of Nutrition & Diet Therapy, 11^th Edition offers a solid foundation in the fundamental knowledge and skills you need to provide effective patient care. Authors Eleanor Schlenker and Joyce Gilbert address nutrition across the lifespan and within the community, with an emphasis on health promotion and the effects of culture and religion on nutrition. Evidence-based information, real-world case scenarios, colorful illustrations, boxes, and tables help you learn how to apply essential nutrition concepts and therapies in clinical practice.

This book reviews and discusses the most relevant epidemiological aspects of OFCs and its prevention. It evaluates the role of folate and other factors in preventing OFC by analysing the health and socio-demographic data collected from a population sample. Individuals that are deficient in folates are suggested to have increase vulnerability to disease, including neurological conditions. Folates are involved in the metabolism of homocysteine which is a sulfur containing non-protein amino acid. This book will also highlight the recent advances made in understanding the effect of dietary folic acid over supplementation on neurological function. Patients with low levels of folic acid and other B vitamins, metabolism disorders, and renal failure have frequently high homocysteine levels that have been especially associated with cardiovascular and bone disease. This book reviews and analyzes the most important results about the effects of folic acid supplementation on clinical targets and it focuses on the effects of folic acid therapy on clinical outcomes of chronic renal failure patients with high homocysteine levels.

This book provides a concise, state-of-the art review of the surgical treatment of metabolic syndrome and diabetes mellitus.  The volume reviews what current practices in surgery and metabolic syndrome and diabetes including the biohormonal effects of the different surgeries. Isolating the effects of the different procedures is critical to the decision tree for type of procedure selected for an individual patient. Specifically for diabetes, this textbook will provide a guide for practitioners to a tailored approach to the treatment. Areas of ongoing research that highlight the minimally invasive approach as well as incorporating what we know of the biochemical results of surgery are presented.  Results of established weight loss procedures and ongoing trials are juxtaposed against some of the more novel techniques to ascertain a best practice.

Metabolic Surgery and the Surgical Treatment of Diabetes serves as a very useful resource for physicians and researchers dealing with, and interested in, this rising epidemic of metabolic syndrome and diabetes.  It  provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.

• Offers guidance on current nutrition treatment of a wide range of inherited metabolic diseases
• Draws on 7 years of lectures delivered through Metabolic University
• Designed to ensure ease of reference for clinicians

About this book

This up-to-date reference on the nutrition management of inherited metabolic diseases (IMD) covers a wide range of these disorders, including phenylketonuria and other aminoacidopathies, organic acidemias, urea cycle disorders, fatty acid oxidation disorders, galactosemia and glycogen storage diseases. Guidance is also provided on laboratory evaluations and biochemical testing and monitoring.

Topics such as newborn screening for IMD, as well as nutrition management during pregnancy and transplantation, are addressed. The book is based on 7 years of lectures delivered through Metabolic University – an interactive, didactic program designed to provide training to dietitians who work with individuals with IMD. This book provides the basic information required to manage nutrition care and is a resource for clinicians new to this complex field.

Table of contents (27 chapters)

·         Introduction to Genetics

Freehauf, Cynthia

Pages 3-14

·         Expanded Newborn Screening for Inherited Metabolic Diseases

Wright, Erica L.

Pages 15-23

·         Nutrition Education

Bernstein, Laurie E. (et al.)

Pages 25-33

·         Pathophysiology of Inherited Metabolic Disease

Baker, Peter R.

Pages 35-45

·         Metabolic Intoxication Syndrome in a Newborn

Giżewska, Maria

Pages 47-57

·         Anabolism: Practical Strategies

Hove, Johan L. K.

Pages 59-62

·         Protein Requirements in Inherited Metabolic Diseases

Yannicelli, Steven

Pages 63-73

·         Laboratory Evaluations in Inherited Metabolic Diseases

Coughlin, Curtis R.

Pages 75-85

·         Phenylketonuria: Phenylalanine Neurotoxicity

Giżewska, Maria

Pages 89-99

·         Phenylketonuria: The Diet Basics

Calcar, Sandy

Pages 101-116

·         Understanding Large Neutral Amino Acids and the Blood-Brain Barrier

Yannicelli, Steven

Pages 117-125

·         Tetrahydrobiopterin Therapy for Phenylketonuria

Jurecki, Elaina

Pages 127-138

·         Maternal Phenylketonuria

Rohr, Fran

Pages 139-147

·         Homocystinuria: Diagnosis and Management

Thomas, Janet A.

Pages 149-158

·         Nutrition Management of Urea Cycle Disorders

Rohr, Fran

Pages 159-171

·         Nutrition Management of Maple Syrup Urine Disease

Calcar, Sandy

Pages 173-183

·         Organic Acidemias

Thomas, Janet A.

Pages 187-201

·         Glutaric Acidemia Type I: Diagnosis and Management

Coughlin, Curtis R.

Pages 203-209

·         Nutrition Management of Glutaric Acidemia Type 1

Bernstein, Laurie E.

Pages 211-220

·         Nutrition Management of Propionic Acidemia and Methylmalonic Acidemia

Calcar, Sandy

Pages 221-228

·         Nutrition Management During Pregnancy: Maple Syrup Urine Disease, Propionic Acidemia, Methylmalonic Acidemia, and Urea Cycle Disorders

Calcar, Sandy

Pages 229-237

·         Fatty Acid Oxidation Defects

Hove, Johan L. K.

Pages 241-254

·         Nutrition Studies in Long-Chain Fatty Acid Oxidation Disorders: Diet Composition and Monitoring

Gillingham, Melanie Boyd

Pages 255-270

·         Nutrition Management of Fatty Acid Oxidation Disorders

Rohr, Fran

Pages 271-282

·         The Diet for Galactosemia

Bernstein, Laurie E. (et al.)

Pages 285-293

·         Glycogen Storage Diseases

Hove, Johan L. K.

Pages 295-305

·         Nutrition Management of Glycogen Storage Disease Type 1

Calcar, Sandy

Pages 307-317

This new edition of the popular and market–leading Diabetes in Old Age features up–to–date and comprehensive information about the key aspects of managing older people with diabetes, predominantly type 2 diabetes.
With a strong evidence–based focus throughout, the entire range of issues surrounding diabetes and its many complications are covered, each with a clear focus on how they relate directly to the older patient. Varying approaches to optimizing diabetes care in the community, primary care and secondary care health care arenas are presented, and   the importance of comprehensive functional assessment is emphasized. Coverage of areas unique to an ageing population of older people with diabetes such as falls management, frailty and sarcopenia, and cognitive dysfunction form a key cornerstone of the book.  In every chapter, best practice points and key learning outcomes are provided, as well as published evidence bases for each major conclusion.

Diabetes in Old Age, 4^th edition is essential reading for diabetologists and endocrinologists, diabetes specialist nurses, primary care physicians, general physicians and geriatricians, podiatrists and dieticians with an interest in diabetes, as well as all health professionals engaged in the delivery of diabetes care to older people.

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome, Second Edition, provides an overview of the current diabetes epidemic, outlines the consequences of this crisis, and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. Contributing experts provide up-to-date global approaches to the critical consequences of metabolic syndrome and make the book an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer?s and neurodegenerative diseases, roles of SGLT2 inhibitors in the treatment of type 2 diabetes, novel biomarkers in diabetes, roles of Trigonella foenum-graecumseed extract in type 2 diabetes, beneficial effects of chromium (III) and vanadium supplements in diabetes, prevention of type 1 diabetes, novel drugs in the therapeutic intervention of type 2 diabetes, eHealth and mobile apps for self-management, artificial pancreatic transplantation, non-invasive glucose monitoring, and the app for glucose regulation. Contains a scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions, plus both Type I and Type II Diabetes Presents both prevention and treatment options

As the worldwide prevalence of morbid obesity among adolescents continues to rise, recent years have seen a large increase in the performance of adolescent bariatric surgery. While surgical intervention often becomes necessary when conservative weight-loss therapies have failed, no standards regarding the post-operative regimen and long-term management of adolescent patients have been established. Thus, the treatment of obesity and its co-morbidities requires a multidisciplinary approach, taking into account epidemiological, clinical, nutritional and genetic aspects of morbid obesity in the pediatric age group.

This volume discusses both conventional therapy and surgical options for morbid obesity in the pediatric age group. In the first part, obesity-related diseases, genetics and psychological factors are analyzed. The second part focuses on current bariatric surgery procedures, including dietary restrictions and guidelines to prevent nutritional deficiencies common after surgery. Therefore, the book will prove an invaluable resource for pediatricians, surgeons, nutritionists, dieticians and all other health professionals who treat adolescent obesity.

 About 29 million Americans (9.3% of the population) in 2012 had diabetes. Approximately 1.25 million American children and adults have type 1 diabetes, and almost all diabetes in children less than 10 years of age is type 1. About 208,000 people younger than 20 years (0.25 % of this age group) have been diagnosed with diabetes (type 1 or type 2). Diabetes care requires a collaborative approach with multi-disciplinary professionals involved from the health, nursing, social and educational fields in order to provide optimal service to the child or adolescent and their family. Early diagnosis, treatment and monitoring can prevent or delay the long-term complications in various organs of the body, and regular care and service to this population is therefore essential. In this book, we provide a short overview of issues involved in diabetes care for children and adolescents.

 Maintaining the high standards that made the previous editions such well-respected and widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Editionprovides a new look at lipid oxidation and highlights recent findings and research. Always representative of the current state of lipid science, this edition provides 16 new chapters and 21 updated chapters, written by leading international experts, that reflect the latest advances in technology and studies of food lipids.

New chapters

• Analysis of Fatty Acid Positional Distribution in Triacylglycerol
• Physical Characterization of Fats and Oils
• Processing and Modification Technologies for Edible Oils and Fats
• Crystallization Behavior of Fats: Effect of Processing Conditions
• Enzymatic Purification and Enrichment and Purification of Polyunsaturated Fatty Acids and Conjugated Linoleic Acid Isomers
• Microbial Lipid Production
• Food Applications of Lipids
• Encapsulation Technologies for Lipids
• Rethinking Lipid Oxidation
• Digestion, Absorption and Metabolism of Lipids
• Omega-3 Polyunsaturated Fatty Acids and Health
• Brain Lipids in Health and Disease
• Biotechnologically Enriched Cereals with PUFAs in Ruminant and Chicken Nutrition
• Enzyme-Catalyzed Production of Lipid Based Esters for the Food Industry: Emerging Process and Technology
• Production of Edible Oils Through Metabolic Engineering
• Genetically Engineered Cereals for Production of Polyunsaturated Fatty Acids

The most comprehensive and relevant treatment of food lipids available, this book highlights the role of dietary fats in foods, human health, and disease. Divided into five parts, it begins with the chemistry and properties of food lipids covering nomenclature and classification, extraction and analysis, and chemistry and function. Part II addresses processing and food applications including modification technologies, microbial production of lipids, crystallization behavior, chemical interesterification, purification, and encapsulation technologies. The third part covers oxidation, measurements, and antioxidants. Part IV explores the myriad interactions of lipids in nutrition and health with information on heart disease, obesity, and cancer, with a new chapter dedicated to brain lipids. Part V continues with contributions on biotechnology and biochemistry including a chapter on the metabolic engineering of edible oils.

 Resulting from ingestion of inappropriately prepared or stored foods containing pathogenic viruses, bacteria, fungi and parasites, foodborne infections have become a significant source of human morbidity and mortality worldwide in recent decades. This may be largely attributable to the remarkable popularity of convenient, ready-to-eat food products, the dramatic expansion of international food trades, and the continuing growth of immuno-suppressed population groups. Although anti-microbial treatments have played a crucial part in the control of foodborne infections in the past, the emergence and spread of anti-microbial resistance render the existing treatments ineffective. Additionally, our limited understanding of the molecular mechanisms of foodborne infections has thwarted our efforts in the development of efficacious vaccines for foodborne pathogens. 

Given the obvious benefits of laboratory models in foodborne disease research, a great number of experiments have been conducted toward the elucidation of host-pathogen interactions in and pathogenic mechanisms of foodborne infections. Forming part of the Food Microbiology series, Laboratory Models for Foodborne Infections presents a state-of-the-art review of laboratory models that have proven valuable in deciphering the life cycle, epidemiology, immunobiology, and other key aspects of foodborne pathogens. 

Written by scientists with respective expertise in foodborne pathogen research, each chapter includes a contemporary summary of a particular foodborne viral, bacterial, fungal, or parasitic infection in relation to its life cycle, epidemiology, clinical features, pathogenesis, host-pathogen interactions, and other related aspects. Besides providing a trustworthy source of information for undergraduates and postgraduates in food microbiology, Laboratory Models for Foodborne Infections offers an invaluable guide for scientists and food microbiologists with interest in exploiting laboratory models for detailed study of foodborne infections.

This comprehensive reference work edited by one of the leading authorities on obesity presents an up-to-date survey of the current scientific understanding of the metabolic syndrome, as well as an overview of the most significant changes to the field over the past 30 years. This volume is a thorough reference for obesity and the metabolic syndrome and will prove an indispensable resource for clinicians and researchers at levels worldwide.​ The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. In addition, when combined with other comorbidities such as hypertension and dyslipidemia, obesity often leads to a patient diagnosis of metabolic syndrome, a very troubling condition that has grown, and is continuing to grow, rapidly each year in prevalence worldwide. Metabolic syndrome is a cluster of conditions ― increased blood pressure, a high blood sugar level, excess body fat around the waist and abnormal cholesterol levels ― that occur together, increasing one’s risk of heart disease, stroke and diabetes. This resource covers the full range of scientific and clinical aspects: epidemiology, genetics, environmental factors, pathophysiology, diseases associated with obesity, and clinical management

Now in its fifth edition, the Textbook of Diabetes has established itself as the modern, well-illustrated, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The fifth edition features an array of brand new chapters, on topics including:

·         Ischaemic Heart Disease

·         Glucagon in Islet Regulation

·         Microbiome and Diabetes

·         Diabetes and Non-Alcoholic Fatty Liver Disease

·         Diabetes and Cancer

·         End of Life Care in Diabetes

as well as a new section on Psychosocial aspects of diabetes.

In addition, all existing chapters are fully revised with the very latest developments, including the most recent guidelines from the ADA, EASD, DUK and NICE.  Via the companion website, readers can access a host of additional online materials such as:

·         200 interactive MCQ's to allow readers to self-assess their clinical knowledge

·         every figure from the book, available to download into presentations

·         fully searchable chapter pdfs

Once again, Textbook of Diabetes provides endocrinologists and diabetologists with a fresh, comprehensive and multi-media clinical resource to consult time and time again.

•             Detailed and up-to-date guidelines for the prevention and treatment of diabetes

•             Everything on epidemiology, etiology, pathogenesis and pathophysiology

•             Combines a focus on clinical sciences with the discussion of basic research

About this book

This book provides the reader with comprehensive information on the epidemiology, etiology, pathogenesis, pathophysiology, clinical features, prevention, and treatment of diabetes with the aim of empowering health care providers in their daily battle against the disease. Diabetes has been identified by WHO and the United Nations as a medical emergency because of the increase in its global prevalence, which may reach one billion in three to four decades if the trend remains unchanged. Despite improved care that is helping to prolong life, diabetes impacts substantially on the quality of life of those affected and kills or disables several million people each year. The disease is systemic because all organs, tissues, and cells suffer in the presence of hyperglycemia and are damaged by the diabetic milieu. Unfortunately, most patients with diabetes will consequently experience chronic diabetic complications. This book, combining basic science with a practical clinical orientation, will be of value for all physicians and nurses who care for patients with diabetes.