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  • 43000lei 415.00 lei

     The Essential Therapy Guide to Cancer, Hematologic Disorders, and Supportive Care--Updated with the Latest Treatment Regimens

    More than 500 treatment regimens

    "Hematology-Oncology Therapy," Second Edition is an up-to-date, comprehensive therapy guide that delivers more than 500 treatment regimens in a succinct, uniform manner. The unique tabular design allows you to instantly locate and implement the proper treatment regimen. Supported by the latest practice guidelines, peer-reviewed literature, and the opinion of experts, "Hematology-Oncology Therapy" integrates extensive information that is critical to both office- and hospital-based practice of hematology and oncology.

    Hematology-Oncology Therapy is divided into three sections:

    Oncology: 
    Provides detailed information about the administration, supportive care, toxicity, dose modification, monitoring, and efficacy of commonly used and recently approved chemotherapeutic regimens, drugs, and biological agents

    Supportive Care, Drug Preparation, Complications, and Screening: 
    Consists of topics commonly encountered in clinical hematology-oncology practice, such as chemotherapy-induced nausea, oncologic emergencies, radiation complications, cancer pain management, cancer screening, and much more

    Selected Hematologic Diseases: 
    Delivers an authoritative guide to therapy for the principal diseases in consultative hematology

    This edition of "Hematology-Oncology Therapy" is enriched by the updating of all chapters as well as the addition of several new chapters; the new "Expert Opinion," which provides recommendations and guidance from experts on the use of treatment regimens; and inclusion of the latest regimens.

  • 150.00 lei

    Ediția a opta a manualului Clasificarea TNM a Tumorilor Maligne pune la dispoziție ultimele consensuri și standarde internaționale utilizate pentru a descrie și a caracteriza corespunzător stadiile maladiilor oncologice. Editat în afiliere cu Uniunea pentru Controlul Internațional al Cancerului (UICC), acest „ghid de buzunar”, autorizat și unanim recunoscut, conține importante clasificări reactualizate pentru localizări tumorale specifice, de care medicii oncologi și profesioniștii din domeniul sănătății, implicați în managementul terapeutic al pacienților afectați de aceste boli, trebuie să țină cont pentru stadializarea, clasificarea, prognosticul și atitudinea terapeutică optimă privind aceste maladii.

           În acest „ghid de buzunar” omologat internațional, se găsesc ultimele noutăți privind atât stadializarea carcinoamelor de cap și gât, a carcinoamelor tiroidiene, esofagiene, gastrice, colorectale, pulmonare, pleurale, a tumorilor cutanate, ovariene, de prostată, ale glandului și ale cortexului suprarenal, cât și stadializarea tumorilor neuroendocrine, a sarcoamelor osoase și de țesuturi moi, dispuse întro manieră simplă și precisă, pe regiuni anatomice.

           În această ediție, sunt introduse noi clasificări pentru carcinoamele orofaringiene p16pozitive, tumorile timice, tumorile neuroendocrine cu origine pancreatică, pentru sarcoame ale coloanei vertebrale și ale pelvisului, sarcoame de țesuturi moi ale capului și ale gâtului, toracice, tumori cu originea în viscerele abdominale și în spațiul retroperitoneal.

            Pentru a înlesni colectarea datelor necesare clasificării și monitorizării maladiilor oncologice în țările cu venituri mici și mijlocii, au fost adăugate noi secțiuni în capitolul Schema Esențială TNM în ceea ce privește tumorile de colon, rect, cele ale glandei mamare și ale colului uterin și carcinoamele prostatei, dar și stadializări simplificate pentru tumorile pediatrice.

           Structura limpede și prelucrată pe baza unor tipare ușor de utilizat a capitolelor care cuprind subdiviziuni anatomice, rețele de drenaj ganglionar, clasificarea clinică și patologică TNM, gradul histopatologic, gruparea pe stadii și, mai nou, gruparea în funcție de prognostic (acolo unde este relevant) permite accesul fără întârziere la informațiicheie.

    Un format reactualizat și cromatica folosită rafinează și sporește gradul de întrebuințare a acestei resurse indispensabile pentru toți specialiștii din medicină, oncologi, radioterapeuți, chirurgi, patologi, asistenți medicali, persoane abilitate să ofere îngrijiri paliative, pentru centre internaționale dedicate terapiilor cu viză oncologică, organizații guvernamentale și nonguvernamentale implicate activ în lupta contra cancerului.

    DESPRE UICC

    „Unim comunitatea afectată de maladiile oncologice pentru a reduce problema globală pe care acestea o reprezintă, promovăm echitatea și integrăm controlul neoplaziilor în agenda universală pentru sănătate și dezvoltare”.


  • 150.00 lei

    Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predict

  • Clinics in liver disease
    Ultima bucata in stoc
    160.00 lei

    The full spectrum of hepatocellular carcinoma is discusssed from epidemiology to prevention to indications for liver transplantation. Prevention, screening, biopsy staging, and diagnosis are all coverered.

  • Oxford Handbook of Oncology Third Edition
    La comanda in aproximativ 4 saptamani
    180.00 lei

    Extensively revised and updated, featuring recent advances in the field of oncology
    Features new chapters on biomarkers and childhood cancers presenting in adults
    Includes evidence-based medicine and additional further reading
    Contain

  • Pocket Radiation Oncology (Pocket Notebook)
    by Tang
    La comanda in aproximativ 4 saptamani
    20200lei 182.00 lei

    Pocket Radiation Oncology is a practical, high-yield reference offering current, evidence-based practices and expert guidance from physicians at the world-renowned MD Anderson Cancer Center. Featuring an easy-to-use, loose-leaf format, it serves as a concise clinical companion and board study guide for medical students, residents, and attending physicians in radiation oncology. Follows the popular Pocket Notebook format, featuring bulleted lists, tables, diagrams, and algorithms that make essential facts easy to find and retain. Emphasizes key literature and clinical trials in every section. Provides solutions to day-to-day management decisions in radiation oncology, including management of radiation induced symptoms, radiation physics, radiation biology, pediatrics, and radiation emergencies.

    ·  Contents

    ·  RADIATION ONCOLOGY PRINCIPLES

    ·  Radiation Biology

    ·  Radiation Physics

    ·  Imaging and Radiology

    ·  Chemotherapy and Immunotherapy

    ·  Clinical Statistics

    ·  SPECIAL RADIATION TECHNIQUES

    ·  Brachytherapy

    ·  Proton Therapy

    ·  Oligometastatic Disease

    ·  Stereotactic Body Radiation Therapy

    ·  Stereotactic CNS Radiosurgery

    ·  CENTRAL NERVOUS SYSTEM

    ·  Low-Grade Gliomas

    ·  High-Grade Gliomas

    ·  Meningioma

    ·  Benign CNS

    ·  Pituitary Adenoma and Craniopharyngioma

    ·  PEDIATRICS

    ·  Medulloblastoma

    ·  Ependymoma

    ·  Intracranial Germ Cell Tumor

    ·  Wilms Tumor

    ·  Neuroblastoma

    ·  Ewing Sarcoma

    ·  Rhabdomyosarcoma

    ·  Osteosarcoma/Retinoblastoma/Brainstem Glioma

    ·  Late Effects

    ·  HEAD & NECK

    ·  Oral Cavity

    ·  Oropharynx

    ·  Sinonasal and Nasopharynx

    ·  Larynx and Hypopharynx

    ·  Salivary Gland Neoplasms

    ·  Thyroid Cancer

    ·  Unknown Head and Neck Primary

    ·  THORACIC

    ·  Early-Stage NSCLC

    ·  Stage III NSCLC

    ·  Small Cell Lung Cancer

    ·  Thymoma and Thymic Carcinoma

    ·  Mesothelioma

    ·  Esophageal Cancer

    ·  GASTROINTESTINAL

    ·  Colorectal Cancer

    ·  Anal Cancer

    ·  Pancreatic Cancer

    ·  Gastric Cancer

    ·  Hepatobiliary Cancer

    ·  BREAST

    ·  General Breast Cancer

    ·  Ductal Carcinoma In Situ (DCIS)

    ·  Early-Stage Breast Cancer (ESBC)

    ·  Locally Advanced Breast Cancer (LABC)

    ·  Inflammatory/Recurrent Breast Cancer

    ·  GENITOURINARY

    ·  Prostate Cancer (Definitive)

    ·  Prostate Cancer (Adjuvant/Salvage)

    ·  Bladder Cancer

    ·  Testicular Cancer

    ·  Penile Cancer

    ·  GYNECOLOGIC

    ·  Cervical Cancer

    ·  Endometrial Cancer

    ·  Vaginal Cancer

    ·  Vulvar Cancer

    ·  Ovarian Cancer

    ·  SKIN/SARCOMA

    ·  Soft Tissue Sarcoma

    ·  Melanoma

    ·  Non-melanoma Skin Cancer

    ·  Merkel Cell Carcinoma

    ·  LYMPHOMA

    ·  Hodgkin Lymphoma

    ·  Diffuse Large B-Cell Lymphoma

    ·  Miscellaneous Hematologic Malignancies

    ·  RADIATION EMERGENCIES, BENIGN DISEASE, AND PALLIATION

    ·  Brain Metastases

    ·  Spine Metastases

    ·  Non-spine Bone Metastases

    ·  Radiation Emergencies

    ·  Benign Disease: Non-neural

    ·  Clinical Setup


  • 20200lei 185.00 lei

    Now fully revised and in its fourth edition, the Oxford Handbook of Oncology has been the essential go-to guide for students and practitioners in oncology for over a decade. The scientific basis and diagnosis of cancers is covered, as well as drugs, biomarkers, and the presentation and psychosocial aspects of oncology. Concise, practical, and comprehensive, there is no better companion for both common conditions and challenging emergencies. The field of oncology has surged forward since the last edition was published and the Oxford Handbook of Oncology has been fully revised and updated to reflect these recent advances so you can be sure that the vital information you need is in your hands. This handbook incorporates changes such as the understanding of the science of cancer, novel therapies in breast, lung, renal, and melanoma, molecular sub-classification of common solid cancers, personalized therapy approaches, new agents in hard to treat cancers, the benefits of new technologies in radiotherapy, and the emerging data on the importance of the immune response. Written by experts in the field to ensure that it is grounded in real life clinical practice, this handbook provides a concise guide to all aspects of oncology for all students, nurses, and junior faculty responsible for the care of cancer patients, while also providing further reading and highlighting areas of controversy for those who need a more detailed understanding.

  • 185.00 lei

    TNM Classification of Malignant Tumours, 7 th Edition provides the latest, internationally agreed–uponstandards to describe and categorize cancer stages and progression.Published in affiliation with the International Union AgainstCancer (UICC), this authoritative guide contains important updatedorgan–specific classifications that oncologists and otherprofessionals who manage patients with cancer need to accuratelyclassify tumours for staging, prognosis and treatment. The major alterations addressed in the 7 th Edition concern carcinomas of the oesophagus and thegastroesophageal junction, stomach, lung, appendix, biliary tract,skin, and prostate. In addition, there are several entirely newclassifications: gastrointestinal carcinoids (neuroendocrine tumours) gastrointestinal stromal tumour upper aerodigestive mucosal melanoma Merkel cell carcinoma uterine sarcomas intrahepatic cholangiocarcinoma adrenal cortical carcinoma. A new approach has also been adopted to separate anatomicalstage groupings from prognostic groupings in which other prognosticfactors are added to T, N, and M categories. These new prognosticgroupings, as well as the traditional anatomical groupings, arepresented for oesophageal and prostate carcinomas. Visit www.wileyanduicc.com formore information about the International Journal of Cancer and our other UICC book titles

  • Paediatric Palliative Medicine
    La comanda in aproximativ 4 saptamani
    20200lei 185.00 lei

    Looking after children with life-limiting conditions is very difficult for both parents and health care professionals. This second edition of Paediatric Palliative Medicine is full of easily-accessible, detailed information , and covers all aspects of the care of children with life-limiting illnesses. It is designed to equip clinicians with the knowledge, and its evidence base, to improve clinical care.

    Using the bestselling Oxford Specialist Handbook format to deliver practical and concise information, this handbook facilitates bedside delivery of effective palliative medicine to children. It includes a quick reference drug formulary and detailed information on medical conditions and symptom control. There are also specific management plans to guide professionals, whether the child is in their own home, in a hospital, or a hospice.

    Many children with long term conditions have symptoms which need management, and the principles of palliative care for children need to be known by all who are involved in their care. The unique significance of this handbook is its capacity to guide professionals who have not trained or had experience of caring for the dying child, as well as for students and trainees interested in paediatric palliative care.

    Children's palliative medicine encompasses symptom control but is not limited to it. This handbook also provides a wealth of information on the philosophy and models that support delivery of palliative medicine to children, as well as the learning and coping skills required in palliative care.

    Fully updated with an expanded formulary and a new chapter on the intensive care unit, this new edition continues to be the authoritative reference tool in paediatric palliative care.

  • Molecular Biology of Cancer
    La comanda in aproximativ 4 saptamani
    21500lei 195.00 lei

    Lauren Pecorino

    • Provides an engaging and manageable route into the complex subject of cancer biology
    • Describes the theoretical basis of cancer biology and shows how this theory is applied to develop new cancer therapies, giving students a clear appreciation of how theoretical knowledge can be translated into therapeutic strategies
    • Draws on the latest research in this dynamic field but presents it in a manner readily accessible to the student

    New to this Edition:

    • New full colour diagrams help students to visualize the key concepts explained in the text more effectively
    • Expanded coverage of tumour immunology and immunotherapy, discussing tumour suppression and tumour promotion mechanisms of the immune system and the exciting new applications of this knowledge towards developing cancer immunotherapies

  • 200.00 lei

    In curand si in limba romana!

    TNM Classification of Malignant Tumours eighth edition provides the latest, internationally agreed-upon standards to describe and categorize cancer stage. 
    • Published in affiliation with the Union for International Cancer Control (UICC)
    • Arranged by anatomical region, this authoritative pocket sized guide contains many important updated organ-specific classifications 
    • There are new classifications for p16 positive oropharyngeal carcinomas, carcinomas of the thymus, neuroendocrine tumours of the pancreas, and sarcomas 
    • To facilitate the collection of stage data for cancer surveillance in low and middle income countries there are new sections on Essential TNM and Paediatric Cancer Stage
    • New colour presentation

  • 22500lei 205.00 lei

    The single most important fact about breast cancer is the great variation in its natural history and its responsiveness to therapy from one patient to another. The clinician must integrate an assessment of the patient's likely course based on clinical and pathological staging and laboratory studies with objective evidence on the benefits of therapy. The primary aim of this book is to provide the clinician with the tools to do just that. Outcomes of clinical trials and details about commonly used drug regimens, drug dosage, and the expected side effects are summarized in generous tables and figures. Medical terminology has been defined and descriptions of the evolution in our thinking and understanding of the disease are often given to provide perspective in the interpretation of evidence from current studies for busy clinicians and trainees alike.

  • 23100lei 210.00 lei

    Concise, portable, and packed with essential information, Manual of Clinical Oncology is an indispensable resource for understanding basic science, clinical findings, and available technology as they relate to the diagnosis and management patients with cancer.  The practical format provides high-yield content useful for participating in rounds ad making diagnostic and therapeutic decisions at the bedside.  Edited by Dr. Bartosz Chmielowski  and Dr. Mary Territo, both from UCLA School of Medicine, this eighth edition carries on the tradition of excellence set forth by longtime editor Dr. Dennis Casciato.

    Key Features:

    • Incorporates recent major achievements in immunotherapies, biologics, and targeted therapies.
    • Features new chapters on the biology of cancer, immunotherapy, and cancer survivorship.
    • Contains numerous diagnostic and treatment algorithms, as well as content on complications, for assistance with clinical decision making.
    • Includes helpful appendices such as a glossary of cytogenetic nomenclature and combination chemotherapy regimens.

    Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience:

    • The ability to download the eBook on multiple devices at one time — providing a seamless reading experience online or offline
    • Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks
    • Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design
    • The ability to highlight text and add notes with one click

  • 40000lei 220.00 lei

     Proposed topics for this issue include: Overview of Colorectal Cancer Genetics; Familial Adenomatous Polyposis; MYH Associated Polyposis; Other genetic colorectal cancer syndromes; Hereditary Nonpolyposis Colorectal Cancer – emphasis on MSH2/MLH1; Hereditary Nonpolyposis Colorectal Cancer – emphasis on PMS2/MSH6; Familial Colorectal Cancer Syndrome Type X; Genome Wide Association Studies and Colorectal Cancer Risk; Genetic Counseling for Hereditary Colorectal Cancer; Genetic Testing for Hereditary Colorectal Cancer; Role of surgery in HNPCC and FAP.

  • 250.00 lei

    Radiation medicine has evolved on several fronts over the past decade and is a useful adjunct in the definitive, adjunctive, and palliative therapy for several solid and hematologic malignancies. This issue coupled with Part I publishing in February 2006

  • 29100lei 263.00 lei

    This book comprehensively and thoroughly reviews the current literature regarding the impact of health disparities and socioeconomic factors on allergic diseases outcomes: such as food allergies and anaphylaxis. The morbidity associated with these conditions is significantly higher in under-privileged populations around the world, including groups who have experienced greater social or economic obstacles to health based on racial, socioeconomic, gender, geographic location. Health Disparities in Allergic Diseases presents evidence and reviews studies from both developed and developing countries that witness health disparities in allergic disease. Concise in format, Health Disparities in Allergic Diseases: An Evidence-Based Look at Causes, Conditions, and Outcomes is made up of 11 expertly written chapters and divided into two parts. It begins with an introductory on global health through an analysis of the theoretical framework of epidemiologic transition. Subsequent chapters then review the socioeconomic and racial variables in treating allergic diseases using a multifactorial approach. Part II discusses disparities in allergic conditions, including asthma health, rhinitis and rhinosinusitis, food allergy, and atopic dermatitis. The book concludes with an exploration of potential strategies to providing solutions for asthmatic impoverished populations. Health Disparities in Allergic Diseases is a practical resource that can be used by researchers and clinicians in the field of allergy who are interested in learning about health related disparities in the context of allergic conditions or who seek solutions for this important issue.

    ·  Part I. Introductory Chapters

    ·  1. Global Health: Reimagining Perspectives

    ·  2. Allergic Diseases in the Developing World: An Emerging Problem or an Overseen Issue?

    ·  3. Racial and Ethnic Disparity in Allergic Diseases in the United States: Example of a Large Country with a Diverse Population

    ·  4. Disparity in Access to Care and Its Impact on Diagnosis and Outcomes of Allergic Diseases

    ·  Part II. Disparity on Allergic Conditions by Disease

    ·  5. Disparity in Rhinitis and Rhinosinusitis

    ·  6. Disparities in Food Allergy

    ·  7. Asthma Health Disparities

    ·  8. Disparity in Atopic Dermatitis

    ·  Part III. Providing Solutions

    ·  9. School-Based Educational Programs to Improve the Knowledge and Outcome in Allergic Conditions

    ·  10. Providing Feasible Solutions for an Asthmatic Impoverished Population

    ·  11. Global and National Networks and Their Role in Fighting Disparity in Allergic Diseases


  • The Bethesda Handbook of Clinical Oncology
    La comanda in aproximativ 4 saptamani
    30500lei 275.00 lei

    The Bethesda Handbook of Clinical Oncology is a comprehensive review of the management of numerous cancer types, emphasizing practical information that can be applied in everyday, fast-moving patient care situations. With contributions from experts and scholars at the National Cancer Institute, National Institutes of Health, Cleveland Clinic, and other renowned institutions, this latest edition has been thoroughly revised with new content and continues to provide practical guidance on how to evaluate, diagnose, and treat cancer patients. Designed for quick and easy accessibility of clinically relevant information. Features a new comprehensive chapter on the principles and practice of immunotherapy. Disease-specific chapters now include information on relevant and appropriate immunotherapeutic drugs. Covers a range of solid-tumor, blood, and other cancers, as well as infection management, nutrition, and palliative care. Combines concise and clear information with tables, images, and algorithms; now with even more algorithms to help fine-tune clinical decision-making. Useful for oncologists, oncology nurses, oncology fellows, residents, and allied health professionals. Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities! Read directly on your preferred device(s), such as computer, tablet, or smartphone Customize for your language, including right-to-left reading, vertical writing, and enhanced annotation in over 30 languages Easily convert to audiobook, powering your content with natural language text-to-speech Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more.

     

     

    ·  Chapter 1 Head and Neck

    ·  Chapter 2 Non–Small Cell Lung Cancer

    ·  Chapter 3 Small Cell Lung Cancer

    ·  Chapter 4 Esophageal Cancer

    ·  Chapter 5 Gastric Cancers

    ·  Chapter 6 Biliary Tract Cancer

    ·  Chapter 7 Primary Cancers of the Liver

    ·  Chapter 8 Gastrointestinal Stromal Tumors (GIST)

    ·  Chapter 9 Colorectal Cancer

    ·  Chapter 10 Pancreatic Cancer

    ·  Chapter 11 Anal Cancer

    ·  Chapter 12 Breast Cancer

    ·  Chapter 13 Renal Cell Cancer

    ·  Chapter 14 Prostate Cancer

    ·  Chapter 15 Bladder Cancer

    ·  Chapter 16 Testicular Carcinoma

    ·  Chapter 17 Ovarian Cancer

    ·  Chapter 18 Endometrial Cancer

    ·  Chapter 19 Cervical Cancer

    ·  Chapter 20 Vulvar Cancer

    ·  Chapter 21 Sarcomas and Malignancies of the Bone

    ·  Chapter 22 Skin Cancers and Melanoma

    ·  Chapter 23 Acute Leukemia

    ·  Chapter 24 Chronic Lymphoid Leukemias

    ·  Chapter 25 Chronic Myeloid Leukemias

    ·  Chapter 26 Chronic Myeloproliferative Neoplasms

    ·  Chapter 27 Multiple Myeloma

    ·  Chapter 28 Non-Hodgkin’s Lymphoma

    ·  Chapter 29 Hodgkin Lymphoma

    ·  Chapter 30 Hematopoietic Cell Transplantation

    ·  Chapter 31 Carcinoma of Unknown Primary

    ·  Chapter 32 Central Nervous System Tumors

    ·  Chapter 33 Endocrine Tumors

    ·  Chapter 34 Hematopoietic Growth Factors

    ·  Chapter 35 Infectious Complications in Oncology

    ·  Chapter 36 Oncologic Emergencies and Paraneoplastic Syndromes

    ·  Chapter 37 Psychopharmacologic Management in Oncology

    ·  Chapter 38 Management of Emesis

    ·  Chapter 39 Nutrition

    ·  Chapter 40 Pain and Palliative Care

    ·  Chapter 41 Central Venous Access Device

    ·  Chapter 42 Procedures in Medical Oncology

    ·  Chapter 43 Basic Principles of Radiation Oncology

    ·  Chapter 44 Clinical Genetics

    ·  Chapter 45 Basic Principles of Immuno-Oncology

    ·  Chapter 46 Anticancer Agents

    ·  Appendix: Performance Status Scales/Scores: Performance Status Criteria


  • Manual of Interventional Oncology
    La comanda in aproximativ 4 saptamani
    295.00 lei

    This Manual of Interventional Oncology by Douglas Coldwell is the culmination of more than 30 years of training, hands-on practice, and skills learned from oncology colleagues. The successful practice of interventional oncology (IO) requires familiarity with all cancer interventions, and the ability to recognize each of their strengths and weaknesses. Acquiring basic knowledge of all facets of the vast, ever-evolving cancer treatment paradigm enables greater understanding of how IO fits into the broad cancer management continuum.

    The first five chapters lay a solid foundation, detailing essentials of medical and surgical oncology and radiation, followed by interventional radiology cancer treatments and agents used in cancer chemotherapy. Twelve cancer-specific chapters cover tumor management and discussion of minimally invasive, imageguided tumor ablation techniques for each type of cancer, as well as IO for pain management and palliative care.

    Key Highlights

    • IO interventions for prevalent cancers such as colorectal, pancreatic, prostate, liver, bladder, breast, lung, and gynecologic - and less common pathologies including neuroendocrine tumors of the gastrointestinal tract and cholangiocarcinoma
    • More than 125 illustrations accompany succinct discussions of pathology, epidemiology, genetics, staging, treatment, outcomes, and IO options for each type of tumor
    • An overview of clinical trials provides a glimpse of future IO innovations
    • A road map to a successful IO career includes pearls gleaned from years of managing a thriving practice

    This definitive guide is a must-have for clinicians working in the field of vascular and interventional radiology. It provides interventional radiologists with the necessary building blocks, information, and techniques to thrive in this rapidly evolving specialty.

  • 40400lei 300.00 lei

    This is a concise yet thorough overview of the medications and approaches used in cancer care - backed by the authority of Harrison's. Harrison's Manual of Oncology is a carry-anywhere guide to the care of patients with cancer. Enhanced by the latest published results, this valuable clinical companion features numerous tables and succinct, outline-style text that puts important information at your fingertips. You will find content that goes beyond the treatment of primary or metastatic disease to encompass the treatment of all therapeutic complications. The opening sections of Harrison's Manual of Oncology are devoted to the classes of agents used to treat cancer and reviews their pharmacology and mechanisms of action. This section is followed by a detailed discussion of the diagnosis, staging, and treatment of all major types of cancer. There is a strong focus on symptom management and complications of treatment, including pain, nausea and vomiting, anemia, febrile neutropenia, metabolicemergencies, thrombosis, psychological issues, and end-of-life care.

  • Perry's The Chemotherapy Source Book
    Ultimile doua bucati in stoc
    335.00 lei

    Perry’s The Chemotherapy Source Book, now in its fifth edition, provides information on the choice of chemotherapeutic agents, the use of combination chemotherapy, and the toxicity of individual drugs. Organized by site, this is the only book of its kind to focus strictly on the clinical practice of chemotherapy, and is meant to serve as a “one-stop shop” for information on choice of chemotherapeutic agents, treatment outlines, grading of side effects, and dose modification.

  • 39500lei 350.00 lei

    Clinicians and scientists are increasingly recognising the importance of an evolutionary perspective in studying the aetiology, prevention, and treatment of human disease; the growing prominence of genetics in medicine is further adding to the interest in evolutionary medicine. In spite of this, too few medical students or residents study evolution. This book builds a compelling case for integrating evolutionary biology into undergraduate and postgraduate medical education, as well as its intrinsic value to medicine. Chapter by chapter, the authors - experts in anthropology, biology, ecology, physiology, public health, and various disciplines of medicine - present the rationale for clinically-relevant evolutionary thinking. They achieve this within the broader context of medicine but through the focused lens of maternal and child health, with an emphasis on female reproduction and the early-life biochemical, immunological, and microbial responses influenced by evolution. The tightly woven and accessible narrative illustrates how a medical education that considers evolved traits can deepen our understanding of the complexities of the human body, variability in health, susceptibility to disease, and ultimately help guide treatment, prevention, and public health policy. However, integrating evolutionary biology into medical education continues to face several roadblocks. The medical curriculum is already replete with complex subjects and a long period of training. The addition of an evolutionary perspective to this curriculum would certainly seem daunting, and many medical educators express concern over potential controversy if evolution is introduced into the curriculum of their schools. Medical education urgently needs strategies and teaching aids to lower the barriers to incorporating evolution into medical training. In summary, this call to arms makes a strong case for incorporating evolutionary thinking early in medical training to help guide the types of critical questions physicians ask, or should be asking. It will be of relevance and use to evolutionary biologists, physicians, medical students, and biomedical research scientists.

  • 365.00 lei

    Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells from patient referral to post-therapy management in a concise and practical format. Providing clinical guidance on the implementation and management of CAR T-cell therapy, this clinical resource keeps you up-to-date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.

  • 376.00 lei

    With full revisions and updates, plus new chapters on herbs and vitamins, "triptans," headache during breast feeding, menstrual migraine, opiate abuse, cervicogenic causes of headache, and exercise and sexual headache, this book presents a full and in-depth range of information for primary care physicians and neurologists.

  • 380.00 lei

    Get a quick, expert overview of the many key facets of lung cancer evaluation and management with this concise, practical resource by Drs. Lynn T. Tanoue and Frank Detterbeck. This easy-to-read reference presents a summary of today's best evidence-based approaches to diagnosis and management in this critical area.
    Table Of Contents: Diagnosis and Evaluation
    1. The Asymptomatic Patient with a Pulmonary Nodule
    2. Evaluation of the Patient with a Radiographic Abnormality Suspicious for Lung Cancer
    3. Lung Cancer Classification Treatment Considerations
    4. Treatment of Early Stage NSCLC
    5. Curative Intent Treatment of Stage III NSCLC
    6. Advanced NSCLC
    7. Treatment of Small Cell Lung Cancer
    8. Special Types of Lung Cancer
    9. Surveillance and Follow-Up Organization, Quality and Efficiency of Care Delivery
    10. Organization of Lung Cancer Care
    11. Achieving Better Quality of Care Additional Components of Comprehensive Care
    12. Tobacco Use Disorder and Treatment
    13. Healthy Patients at Risk for Lung Cancer: Whether, How and Who to Screen
    14. Symptom Management in Patients with Lung Cancer
    15. Diagnosis and Management of Treatment Related Pulmonary Complications Perspectives
    16. Lung Cancer - Where Are We Now and What is the Future?

  • 77000lei 385.00 lei

     Interventional Oncology is a concise, practical guide to state-of-the-art, image-guided procedures that are among the most innovative and effective cancer treatment options available today. Each chapter is presented in a similar format that includes indications, contraindications, patient selection, pre-procedure workup, technique, post procedure management, and clinical data. This book is the perfect high-yield manual for practitioners to consult before seeing oncology patients, as well as for intra and post-procedure management.
    Key Features:


    High-quality color illustrations and multi-modality clinical images


    Covers all the latest interventional oncology procedures


    Chapter authors are leading authorities in the field


    Tips and pearls at the end of each chapter and a comprehensive set of references

    This book is an excellent clinical guide for seasoned interventional radiologists as well as trainees in interventional oncology to consult on a day–to–day basis.

  • 41500lei 385.00 lei

    Understand and apply the scientific advances that are revolutionizing cancer research and practice with Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer. Derived from DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology - widely hailed as the definitive clinical reference in oncology - the second editon of this popular Primer focuses on the molecular biology information that is of critical importance to research scientists and clinical oncologists alike.* Get up-to-date, dependable coverage of every important frontier in aspect of the molecular biology of cancer with contributions from a noteworthy roster of leading scientists and clinicians, featuring an updated version of the classic "Hallmarks of Cancer" by Hanahan and Weinberg* See how molecular biology advances are impacting clinical practice with separate chapters on each of the 19 most common cancer types.* Navigate the challenges and ethical dilemmas of cancer genetics with a thorough section chapters on genetic counseling and genetic testing.Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to:*Complete content with enhanced navigation* A powerful search that pulls results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

  • Cardiac Management of Oncology Patients
    La comanda in aproximativ 4 saptamani
    386.00 lei

    This book is designed for clinical cardiologists and other physicians working with cardiac patients, where specific specialized teams of cardio-oncologists are not available and who are called to perform a clinical consultation to evaluate both the cardiac condition and the eligibility for chemotherapy or radiotherapy treatment, and to evaluate if a cancer treatment produces toxic effects on a patient treated with chemo or radiotherapy and if appearance of new symptoms is due to this treatment. In recent years, progress in oncologic therapy has resulted in important developments and the prognostic improvement of patients with malignancy. The cornerstone of chemotherapy are the anthracyclines (and the analogue Mitoxantrone), that are direct cellular toxic agents and that are among the most powerful anti-neoplastic drugs, but their cardiac toxicity is well known. Significant breakthroughs in cancer therapy have also been achieved with the introduction of signalling inhibitors, such as VEGF inhibitors, HERB2 inhibitors or TK inhibitors used alone or in combination with direct cellular toxic drugs. However, these signalling inhibitors may interact also with cardiovascular signalling and therefore may have functional or structural effects on the myocardium. This can be permanent or reversible, with impairment of the global conditions and important side effects, and increase both morbidity and mortality and worsening of quality of life. Chemotherapy and radiotherapy can have acute detrimental effects that can be present for years after treatment and that can lead to cardiac consequences also after long periods of no clinic sequelae. Patient numbers with cancer problems will dramatically increase in the next years and thus every cardiologist will need to have the correct information and the skills to manage these situations in the correct way. This book will provide these tools for them.

  • Immunotherapies for Allergic Disease
    by Cox
    La comanda in aproximativ 4 saptamani
    43200lei 389.00 lei

    Get a quick, expert overview of the use of current and novel immunotherapies for use in the management and treatment of allergic reactions and diseases. This concise resource by Dr. Linda Cox covers the full range of allergic disease, including aeroallergens, asthma, food allergies, atopic dermatitis, and stinging insects. With essential coverage of allergen immunotherapies in addition to key topics on emerging allergen-associated immunomodulators, this succinct, comprehensive reference consolidates today’s available information on this timely topic into a single convenient resource.

    • Discusses timely topics such as food tolerance, allergy, and allergen unresponsiveness; biologics for COPD and pediatric asthma; and adherence and pharmacoeconomics.
    • Summarizes practical guidelines and recommendations for use of immunotherapies in clinical practice.
    • Provides insight into the background and history of immunotherapies as a treatment for allergic disease.
    • Includes developments on the horizon, including alternative immunotherapy routes and modified allergens.

     

     

    ·  Section 1. Background

    ·  Chapter 1. Allergen immunotherapy: a historical progression

    ·  Historical development

    ·  Early materials and methods

    ·  Specific treatment: allergic rhinitis

    ·  Allergic asthma

    ·  Insect venom immunotherapy

    ·  Food allergy immunotherapy

    ·  Decreasing side effects of immunotherapy

    ·  Potency/standardization

    ·  Mechanisms of allergy

    ·  Length of treatment

    ·  Routes of immunotherapy

    ·  Concluding thoughts

    ·  Chapter 2. Definition of an allergen

    ·  Classification of allergens

    ·  Naming allergenic products

    ·  Properties of allergens

    ·  Rationale for the use of single allergens and allergenic extracts

    ·  Concluding thoughts

    ·  Chapter 3. Allergen standardization and manufacturing

    ·  Introduction

    ·  Classification and manufacture of allergen extracts in the United States

    ·  Standardization of allergen extracts in the United States

    ·  A standardization algorithm

    ·  Conclusions

    ·  Section 2. Allergic diseases

    ·  Chapter 4. Atopic dermatitis

    ·  Background

    ·  Prospective studies with favorable results of SCIT for AD

    ·  Prospective studies with favorable results of SLIT for AD

    ·  Negative studies of IT for AD

    ·  Published reviews of IT for AD

    ·  Practice guidelines

    ·  Small molecules: phosphodiesterase inhibitors

    ·  Small molecules: Janus Kinase/signal transducer and activator of transcription (JAK/STAT pathway)

    ·  Current monoclonal therapies: dupilumab

    ·  Other biologic immunotherapies under investigation

    ·  Potentially promising and emerging biologic therapies

    ·  Nemolizumab (anti-IL-31)

    ·  Other historical and investigatory biologic immunotherapies

    ·  Tezepelumab (anti-TSLP)

    ·  Rituximab (anti-CD20)

    ·  Omalizumab (anti-IgE)

    ·  Mepolizumab (anti-IL-5)

    ·  Ustekinumab (anti-p40 subunit)

    ·  Summary of biologic immunotherapies for atopic dermatitis

    ·  Chapter 5. Food allergy

    ·  Introduction

    ·  Epicutaneous immunotherapy trials

    ·  Immune mechanisms of AIT clinical trials of additional forms of AIT

    ·  Future directions

    ·  Chapter 6. Venom immunotherapy

    ·  Background

    ·  Patient selection

    ·  High-risk patients

    ·  Hymenoptera venom extracts

    ·  Initiation of VIT

    ·  Efficacy and safety

    ·  Maintenance/monitoring

    ·  Duration

    ·  Mechanism of VIT

    ·  Summary

    ·  Section 3. Mechanisms of allergen immunotherapy

    ·  Chapter 7. Mechanisms of subcutaneous allergen immunotherapy against inhaled aeroallergens

    ·  Introduction

    ·  Mechanisms of SCIT Studies

    ·  Desensitization and reduction of local mast cells, basophils, and eosinophils

    ·  Reduction of type 2 innate lymphoid cells

    ·  Decreases in Th2 lymphocyte responses

    ·  Th1 immunodeviation and changes in Th2/Th1 ratios

    ·  Increase in T regulatory cells and IL-10 mediated effects

    ·  Reduced T follicular helper cells and increased T follicular regulatory cells

    ·  Increase in B regulatory cells

    ·  Initial increase followed by persistent decrease in IgE

    ·  Generation of blocking IgG and IgA antibodies

    ·  How novel mechanisms can improve aeroallergen SCIT

    ·  Summary

    ·  Chapter 8. Sublingual immunotherapy: aeroallergen and venom

    ·  Introduction

    ·  Early studies of sublingual immunotherapy

    ·  Sublingual immunotherapy tablets

    ·  Mechanisms of sublingual immunotherapy

    ·  Efficacy and safety of sublingual immunotherapy

    ·  Sublingual versus subcutaneous immunotherapy

    ·  Allergists use of sublingual immunotherapy

    ·  Cost effectiveness of sublingual immunotherapy

    ·  Sublingual immunotherapy for venom allergy

    ·  Conclusion

    ·  Chapter 9. Food tolerance, allergy, and allergen unresponsiveness

    ·  Food antigen-specific immune responses in health

    ·  The role of regulatory T cells in food tolerance

    ·  Role of immunoglobulins in oral tolerance

    ·  Development of food allergy

    ·  The role of microbiota in food tolerance versus allergy

    ·  Oral tolerance, desensitization, and sustained unresponsiveness: mechanisms of therapeutically induced food tolerance

    ·  Summary

    ·  Chapter 10. Clinical markers to allergen immunotherapy response

    ·  Introduction

    ·  IgE (total IgE, specific IgE, and sIgE/total IgE ratio)

    ·  IgG subtypes

    ·  Serum inhibitory activity for IgE

    ·  Basophil activation

    ·  Cytokines and chemokines

    ·  Cellular biomarkers

    ·  In vivo biomarkers

    ·  Novel biomarkers/developments

    ·  Concluding remarks

    ·  Chapter 11. Biologics in the management of chronic obstructive pulmonary disease

    ·  Introduction

    ·  Targets for biological agents in COPD

    ·  High-T2 inflammation in COPD

    ·  Systemic comorbidities in COPD

    ·  Targets specific to parenchymal lung destruction in COPD

    ·  Conclusions

    ·  Section 4. Allergen immunotherapy (AIT) and allergen immunomodulatory (AIM) therapies

    ·  Chapter 12. Breakthroughs in subcutaneous allergy immunotherapy

    ·  Introduction

    ·  Proven efficacy in allergic diseases

    ·  Evidence for efficacy of SCIT with mixtures of unrelated allergens

    ·  Evidence for allergen specificity of SCIT

    ·  Determination of optimal dosing of SCIT

    ·  Evidence of disease modification

    ·  Long-term effect on offspring

    ·  Evidence of modification of underlying immunologic derangement

    ·  Necessary duration of SCIT to achieve disease modification

    ·  Safety of subcutaneous immunotherapy

    ·  Alternative injection schedules

    ·  Compounding allergen mixtures

    ·  Adjuvants

    ·  Comparative efficacy of subcutaneous versus sublingual immunotherapy

    ·  Chapter 13. Breakthroughs in sublingual immunotherapy

    ·  AIT contraindications

    ·  Novel AIT approaches in asthma

    ·  Emerging approaches for food allergy

    ·  Key points

    ·  Chapter 14. Food immunotherapy

    ·  Introduction

    ·  Oral immunotherapy

    ·  Safety and tolerability of oral immunotherapy

    ·  Sublingual immunotherapy

    ·  Epicutaneous immunotherapy

    ·  Other novel approaches

    ·  Conclusion

    ·  Chapter 15. Adherence and pharmacoeconomics

    ·  SCIT studies

    ·  Pharmacoeconomic data on sublingual immunotherapy

    ·  Cost-effectiveness of SCIT versus SLIT

    ·  Conclusions

    ·  Section 5. AIT and immunomodulatories in investigation

    ·  Chapter 16. Unconventional but promising routes for allergen immunotherapy: an update on intralymphatic and epicutaneous immunotherapy

    ·  Introduction

    ·  Measures to enhance AIT efficacy

    ·  Measures to improve AIT safety

    ·  Intralymphatic allergen immunotherapy

    ·  Epicutaneous allergen immunotherapy

    ·  Methods to improve EPIT

    ·  Outlook for EPIT

    ·  Chapter 17. Modified allergens: peptides, fragments, and recombinant allergens

    ·  Introduction

    ·  Disadvantages of natural allergen extracts

    ·  Types of recombinant allergens and hypoallergenic derivatives

    ·  Allergoids

    ·  Recombinant wild-type allergens

    ·  Fragments and recombinant hypoallergenic derivatives

    ·  Synthetic T cell epitope–derived peptides

    ·  Contiguous overlapping peptides

    ·  Synthetic B cell epitope–derived peptides

    ·  Summary and conclusion

    ·  Section 6. Allergen immunomodulatories

    ·  Chapter 18. Effect of immunomodulators on allergen immunotherapy

    ·  Biological agents

    ·  Immunomodulators

    ·  Chapter 19. Anti-IgE therapy

    ·  Introduction

    ·  Anti-IgE therapy in specific diseases

    ·  Practical matters

     

     

  • 43500lei 390.00 lei

    This book addresses the day-to-day treatment planning issues that radiation oncologists are likely to encounter during the treatment of breast cancer patients and provides numerous practical “tips” that will assist in navigation of the treatment planning process, from delineation of the tumor boundaries to discrimination of adjacent normal tissues and critical structures at risk of radiation injury. Differences in target delineation and treatment planning according to technique are emphasized, with coverage of conventional radiation therapy and advanced techniques including cardiac-sparing approaches, e.g., using active breathing control, intensity-modulated radiation therapy, proton beam therapy, and electron beam therapy post mastectomy. Individual chapters also focus on radiation setup and verification techniques and radiation treatment planning systems. The book, which is part of the Springer series Practical Guides in Radiation Oncology, is designed for hands-on use by radiation oncology residents/fellows in training and practicing radiation oncologists.

  • Harrison's Hematology and Oncology, 3e
    La comanda in aproximativ 4 saptamani
    43800lei 390.00 lei

    Hematology and Oncology-with all the authority of Harrison's!

     

    Featuring the chapters on Hematology and Oncology that appear in the landmark Harrison's Principles of Internal Medicine, 17e, this compact clinical companion delivers all the latest knowledge in the field, backed by the scientific rigor and reliability that have defined Harrison's.

    Featuring a full color format, chapters from the HPIM 17, material from the acclaimed Harrison's DVD, selfassessment questions, and selected content from Harrison's Practice, Harrison's Hematology and Oncology serves as a great textbook and clinical reference for a range of users from students to seasoned clinicians.

    Harrison's Hematology and Oncology delivers:

    §  A unique single-source reference delivering hard-to-find information

    §  Integration of pathophysiology with clinical management topics in each of the diseases-oriented chapters

    §  52 chapters written by physicians who have made seminal contributions in their areas of expertise

    §  115 high-yield self-assessment Q&A for exam and board review

    §  Complete coverage of need-to-know topics, including the latest information on hematopoiesis, cancer cell biology, and cancer prevention

    §  Helpful appendix that highlights laboratory values of clinical importance

    Everything you would expect from Harrison's tailored to your specialty:
      SECTION I: THE CELLULAR BASIS OF HEMATOPOIESIS 

      SECTION II: CARDINAL MANIFESTATIONS OF HEMATOLOGIC DISEASE 

      SECTION III: ANEMIAS 

      SECTION IV: MYELOPROLIFERATIVE DISORDERS 

      SECTION V: HEMATOLOGIC MALIGNANCIES 

      SECTION VI: DISORDERS OF HEMOSTASIS 

      SECTION VII: BIOLOGY OF CANCER 

      SECTION VIII: PRINCIPLES OF CANCER PREVENTION AND TREATMENT 

      SECTION IX: NEOPLASTIC DISORDERS 

      SECTION X: ENDOCRINE NEOPLASIA 

      SECTION XI: REMOTE EFFECTS OF CANCER 

      SECTION XII: ONCOLOGIC EMERGENCIES AND LATE EFFECTS AND COMPLICATIONS OF CANCER AND ITS TREATMENT

  • 391.00 lei

    Description:

    This issue of Surgical Oncology Clinics of North America, edited by Dr. John Ridge, is devoted to Head and Neck Cancer.Articles in this issue include: Epidemiology of Head and Neck Cancer; Molecular Biology and Immunology; Examination of the patient with Head and Neck Cancer; Imaging of Head and Neck Cancer; Principles of Radiation Treatment; Principles of Chemotherapy; Principles and Practice of Reconstructive Surgery; Oral Cavity; Oropharynx; Unknown primary; Larynx and Hypopharynx; Nasopharynx; Nose and Sinus; Head and Neck Skin Cancer; and Tumors of the major Salivary Glands.

     

     Table of Contents:

    ·  Copyright

    ·  Contributors

    ·  Consulting Editor

    ·  Editor

    ·  Authors

    ·  Forthcoming Issues

    ·  Forthcoming Issues

    ·  Recent Issues

    ·  Foreword: A Long Overdue Discussion of Head and Neck Cancer

    ·  Preface: Why “Head and Neck Cancer”?

    ·  Epidemiology of Head and Neck Cancer

    ·  Key points

    ·  Introduction

    ·  Risk factors for head and neck cancer

    ·  Trends in head and neck cancer incidence

    ·  Prognosis

    ·  Summary

    ·  Molecular Biology and Immunology of Head and Neck Cancer

    ·  Key points

    ·  Distinct etiologic subsets of head and neck squamous cell carcinoma

    ·  Genetic alterations

    ·  Major pathways

    ·  Examination of the Patient with Head and Neck Cancer

    ·  Key points

    ·  History taking in the head and neck

    ·  Overall function

    ·  Physical examination

    ·  Special considerations by anatomic site

    ·  Summary

    ·  Radiation Treatment of Head and Neck Cancer

    ·  Key points

    ·  Introduction

    ·  Technical principles of modern head and neck radiation therapy

    ·  Clinical evidence in support of highly conformal therapy

    ·  Results of induction and concurrent chemoradiation

    ·  Uniquely evolving issues in oropharyngeal carcinoma

    ·  Posttreatment surveillance

    ·  Postradiation resection

    ·  Sequencing of other therapies around surgery

    ·  Future advances in radiation therapy

    ·  Summary

    ·  Systemic Therapy for Squamous Cell Carcinoma of the Head and Neck

    ·  Key points

    ·  Systemic therapy for localized disease

    ·  Postoperative chemoradiation for squamous cell cancer of the head and neck

    ·  Palliative systemic therapy for recurrent and metastatic disease

    ·  Current investigational approaches

    ·  Summary

    ·  Imaging for Head and Neck Cancer

    ·  Key points

    ·  Head and neck cancer

    ·  Rationale for modality selection

    ·  Diagnostic imaging technique

    ·  Interpretation/assessment of clinical images

    ·  Summary

    ·  Principles and Practice of Reconstructive Surgery for Head and Neck Cancer

    ·  Key points

    ·  Patient evaluation overview

    ·  Soft tissue reconstruction

    ·  Maxilla reconstruction

    ·  Tongue reconstruction

    ·  Mandible reconstruction

    ·  Pharyngeal reconstruction

    ·  Summary

    ·  Cancer of the Oral Cavity

    ·  Key points

    ·  Introduction

    ·  Anatomy of the oral cavity

    ·  Epidemiology and etiology

    ·  Pathology

    ·  Clinical presentation and evaluation

    ·  Treatment

    ·  Outcomes of treatment

    ·  Summary

    ·  Cancer of the Oropharynx

    ·  Key points

    ·  Introduction

    ·  Pathogenesis and prognosis for oropharyngeal malignancies

    ·  Risk-adapted treatment strategies for oropharyngeal squamous cell carcinoma

    ·  Summary

    ·  Treatment/Comparative Therapeutics

    ·  Key points

    ·  Introduction

    ·  Patient evaluation overview

    ·  General principles of therapy

    ·  Radiation therapy in early stage disease

    ·  Combination therapies

    ·  Surgical treatment options

    ·  Treatment resistance and recurrence

    ·  Evaluation of outcome and long-term recommendations

    ·  Summary/discussion

    ·  Nasopharyngeal Carcinoma

    ·  Key points

    ·  Introduction

    ·  Patient evaluation overview

    ·  Primary therapy

    ·  Combination therapies

    ·  Local recurrence/resistance

    ·  Evaluation of outcome and long-term recommendations

    ·  Summary

    ·  Cancers of the Nose, Sinus, and Skull Base

    ·  Key points

    ·  Introduction

    ·  Risk factors

    ·  Anatomy of the nose and sinus

    ·  Anatomy of the anterior skull base

    ·  Sinonasal carcinomas

    ·  Management

    ·  Approaches

    ·  Role of radiation

    ·  Role of chemotherapy

    ·  Summary

    ·  Evaluation and Management of Head and Neck Squamous Cell Carcinoma of Unknown Primary

    ·  Key points

    ·  Introduction

    ·  Patient evaluation

    ·  Initial treatment

    ·  Summary

    ·  Cutaneous Malignancy of the Head and Neck

    ·  Key points

    ·  Introduction

    ·  Epidemiology

    ·  Risk factors

    ·  Nonmelanoma skin cancer

    ·  Melanoma

    ·  Summary

    ·  Cancers of Major Salivary Glands

    ·  Key points

    ·  Histologic classification and staging

    ·  Presentation and work-up

    ·  Selected histologic subtypes of major salivary gland malignancies

    ·  Treatment

  • 391.00 lei

    Description:

    This issue of Surgical Oncology Clinics of North America is devoted to "Breast Cancer" and is edited by Lisa Newman, MD, of the University of Michigan.  Expert authors in this issue review this topic in articles such as: Applications for Breast MRI; Lobular Neoplasia; Epidemiology of Breast Cancer; Percutaneous Ablation of Breast Tumors; Triple Negative Breast Cancer and the Basal Breast Cancer Subtype; Molecular Profiling of Breast Cancer; Surgical Leadership and Standardization of Multidisciplinary Breast Cancer Care; Neoadjuvant/Primary Systemic Therapy for Breast Cancer; Management of the Clinically Node-Negative Axilla in Patients with Primary and Locally-Recurrent Breast Cancer; Management of the Axilla in Patients with Node-Positive Breast Cancer; Prophylactic Bilateral Mastectomy and Contralateral Prophylactic Mastectomy; Advances in Reconstruction of Mastectomy and Lumpectomy Defects; Nipple-Sparing Mastectomy; and Breast Cancer Disparities.

     

    Tabel of contents:

     

    ·  Foreword: Breast Cancer

    ·  Preface: Breast Cancer

    ·  Epidemiology of Breast Cancer

    ·  Key points

    ·  Introduction

    ·  Incidence, prevalence, and mortality

    ·  Risk factors

    ·  History of benign breast disease

    ·  Lifestyle and dietary

    ·  Radiation exposure

    ·  Summary

    ·  Prophylactic Bilateral Mastectomy and Contralateral Prophylactic Mastectomy

    ·  Key points

    ·  Introduction

    ·  Risk assessment

    ·  Epidemiology and decision making

    ·  Operative technique

    ·  Sequelae of prophylactic mastectomy

    ·  Cost-effectiveness of prophylactic mastectomy

    ·  Summary

    ·  Applications for Breast Magnetic Resonance Imaging

    ·  Key points

    ·  Introduction

    ·  MRI for screening

    ·  MRI for treatment selection

    ·  MRI for occult breast cancer

    ·  MRI to select patients for APBI

    ·  MRI-NAC

    ·  Summary

    ·  Molecular Profiling of Breast Cancer

    ·  Key points

    ·  Molecular profiling of intrinsic subtypes of breast cancer

    ·  Molecular prediction and prognostication for treatment decision making

    ·  Impact of molecular profiling on practice patterns

    ·  Summary

    ·  Management of the Clinically Node-Negative Axilla in Primary and Locally Recurrent Breast Cancer

    ·  Key points

    ·  Introduction

    ·  Sentinel lymph node biopsy in clinically node-negative primary breast cancer

    ·  Management of the clinically node-negative axilla in locally recurrent breast cancer

    ·  Summary

    ·  Management of Axillary Disease

    ·  Key points

    ·  Introduction

    ·  Staging of axillary nodal region

    ·  Clinically node-negative patient

    ·  Clinically node-positive patients

    ·  Ongoing and upcoming clinical trials addressing axillary disease management

    ·  Adjuvant radiation therapy

    ·  Summary

    ·  Lobular Neoplasia

    ·  Key points

    ·  Introduction

    ·  Anatomic pathology and classification

    ·  Molecular features and pathophysiology

    ·  Epidemiology and clinical features

    ·  Clinical management

    ·  Neoadjuvant Therapy in the Treatment of Breast Cancer

    ·  Key points

    ·  Introduction

    ·  Rationale for neoadjuvant chemotherapy

    ·  Comparison of neoadjuvant to adjuvant systemic therapy

    ·  Prognostic significance of tumor response

    ·  Monitoring of response to neoadjuvant therapy

    ·  Impact of neoadjuvant chemotherapy on local-regional therapies

    ·  Summary

    ·  Advances in Breast Reconstruction of Mastectomy and Lumpectomy Defects

    ·  Key points

    ·  Introduction

    ·  Reconstruction of mastectomy defects

    ·  Reconstruction of lumpectomy defects

    ·  Technological aids in breast reconstruction

    ·  Possible directions in the future

    ·  Supplementary data

    ·  Nipple-Sparing Mastectomy

    ·  Key points

    ·  Historical perspective

    ·  Birth of breast reconstruction and subcutaneous mastectomy

    ·  Cosmetic importance of the nipple-areola complex

    ·  Autologous tissue flap reconstruction and skin-sparing mastectomy

    ·  Nipple areolar preservation or reconstruction

    ·  Birth of the areola-sparing mastectomy

    ·  Rebirth of the nipple-sparing mastectomy

    ·  Technical development

    ·  Timeline

    ·  Long-term outcomes data

    ·  Lessons learned

    ·  Lessons to be learned: impact on body image and quality of life

    ·  Summary

    ·  Supplementary data

    ·  Basal-Like and Triple-Negative Breast Cancers

    ·  Key points

    ·  Introduction

    ·  Clinical and histopathologic features

    ·  Epidemiology and risk factors

    ·  Targeted therapies

    ·  Summary

    ·  Breast Cancer Disparities

    ·  Key points

    ·  Introduction

    ·  Disentangling socioeconomic resources from racial-ethnic identity in explaining breast cancer disparities

    ·  Epidemiology and risk factors for breast cancer associated with African ancestry

    ·  Breast cancer in African American women: implications for screening mammography recommendations

    ·  Breast cancer risk assessment and chemoprevention in African American women

    ·  BRCA genetic testing, hereditary susceptibility, and African ancestry

    ·  Summary

    ·  Nonsurgical Ablation of Breast Cancer

    ·  Key points

    ·  Introduction

    ·  Clinical outcomes

    ·  Radiofrequency ablation

    ·  Cryoablation

    ·  High-intensity focused ultrasonography

    ·  Microwave thermotherapy

    ·  Novel technologies

    ·  Concerns for the future

    ·  Summary

    ·  Surgical Leadership and Standardization of Multidisciplinary Breast Cancer Care

    ·  Key points

    ·  History of multidisciplinary care

    ·  Standardization of the multidisciplinary breast cancer care

    ·  The national accreditation program for breast centers

  • 391.00 lei

    Description:

    This issue of Surgical Oncology Clinics of North America, edited by Dr. Lawrence Wagman, is devoted to Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver. Articles in this issue include: Epidemiology of Hepatomas; Risk Modeling: disease prevalence, outcome from treatment; Imaging; Resection techniques; Ablation techniques; Complications of interventions; Trans-arterial chemo-embolization (TACE); Continuous hepatic artery infusion (CHAI); Selective interstitial radiation therapy (SIRT) and External beam radiation therapy (EBRT); Systemic chemotherapy of HCC and Cholangiocarcinoma; and Systemic chemotherapy and CRC metastases.

     Table of Contents:

    ·  Contributors

    ·  Consulting Editor

    ·  Editor

    ·  Authors

    ·  Forthcoming Issues

    ·  Forthcoming Issues

    ·  Recent Issues

    ·  Foreword: Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver

    ·  Preface: Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver

    ·  Epidemiology of Hepatocellular Carcinoma

    ·  Key points

    ·  Introduction

    ·  Incidence

    ·  Risk factors

    ·  Patient factors

    ·  Economic/public health aspect

    ·  Summary

    ·  Imaging Approach to Hepatocellular Carcinoma, Cholangiocarcinoma, and Metastatic Colorectal Cancer

    ·  Key points

    ·  Introduction

    ·  Liver imaging modalities

    ·  Imaging liver lesions

    ·  Summary

    ·  Prognostication Systems as Applied to Primary and Metastatic Hepatic Malignancies

    ·  Key points

    ·  Introduction

    ·  Primary hepatic malignancies

    ·  Hepatic colorectal adenocarcinoma metastases

    ·  Summary

    ·  Modern Technical Approaches in Resectional Hepatic Surgery

    ·  Key points

    ·  Introduction

    ·  Indications for liver resection

    ·  Preoperative functional evaluation

    ·  Anatomy and terminology of liver resection

    ·  Technical considerations and outcomes after liver surgery

    ·  Positioning and setup

    ·  Incisions and retraction

    ·  Intraoperative ultrasonography

    ·  Hepatic mobilization

    ·  Approach to inflow control

    ·  Approach to outflow control

    ·  Techniques of parenchymal transection

    ·  Specific procedures

    ·  Complications Following Hepatectomy

    ·  Key points

    ·  Post-hepatectomy hemorrhage

    ·  Post-hepatectomy venous thrombosis/thromboembolism

    ·  Post-hepatectomy portal vein and hepatic artery thrombosis

    ·  Bile leak

    ·  Post-hepatectomy liver failure

    ·  Summary

    ·  Ablative Technologies for Hepatocellular, Cholangiocarcinoma, and Metastatic Colorectal Cancer of the Liver

    ·  Key points

    ·  Introduction

    ·  Ablation technologies

    ·  Patient selection

    ·  Ablation approaches

    ·  Perioperative process

    ·  Outcomes

    ·  Hepatic Artery Infusion Chemotherapy for Liver Malignancy

    ·  Key points

    ·  Introduction

    ·  Technical aspects

    ·  Management of variant hepatic arterial anatomy

    ·  Postoperative management and treatment surveillance

    ·  Complications

    ·  Clinical outcomes with hepatic artery infusion chemotherapy

    ·  Unresectable colorectal cancer metastases

    ·  Hepatic artery infusion chemotherapy and primary liver tumors

    ·  Hepatic artery infusion chemotherapy and noncolorectal liver metastases

    ·  Summary

    ·  Transarterial Chemoembolization for Primary Liver Malignancies and Colorectal Liver Metastasis

    ·  Key points

    ·  Introduction

    ·  Principles of transarterial chemoembolization

    ·  Hepatocellular carcinoma

    ·  Intrahepatic cholangiocarcinoma

    ·  Metastatic colorectal carcinoma to the liver

    ·  Summary

    ·  Y90 Selective Internal Radiation Therapy

    ·  Key points

    ·  Introduction

    ·  Outcomes

    ·  Complications

    ·  Summary

    ·  Systemic Therapy for Hepatocellular Carcinoma and Cholangiocarcinoma

    ·  Key points

    ·  Scope of the problem

    ·  Hepatocellular carcinoma

    ·  Sorafenib

    ·  Challenges with treatment

    ·  Failure of clinical trials

    ·  Liver-directed therapy and sorafenib

    ·  Cholangiocarcinoma

    ·  Summary

    ·  Integrating Systemic and Surgical Approaches to Treating Metastatic Colorectal Cancer

    ·  Key points

    ·  Introduction

    ·  Systemic regimens for metastatic colorectal cancer

    ·  Maintenance regimens

    ·  Potentially curable advanced colorectal cancer

    ·  Role for resection of primary tumor

    ·  Summary and future directions

  • 47500lei 400.00 lei

    This up-to-date, hands-on manual offers clear guidance on contouring and treatment planning for both standard and advanced radiation therapy in patients with gastrointestinal cancers and simultaneously draws together the available relevant clinical data for each type of cancer with a view to driving treatment recommendations. The full range of malignancies is covered, including esophageal, gastric, pancreatic, hepatic, biliary, colon, rectal, and anal cancers and pelvic recurrences. Additional chapters are devoted to stereotactic body radiation therapy (SBRT) to the liver for metastatic disease. The management of gastrointestinal cancers with radiation therapy has become increasingly complex. Specifically, the emergence of new techniques such as SBRT and intensity-modulated radiation therapy (IMRT) has further increased the need to understand how to contour targets and organs at risk, how to perform safe treatment planning, and when to apply these technologies. In this context, Radiation Therapy for Gastrointestinal Cancers represents an ideal reference for both established clinical radiation oncologists and radiation oncology residents.

  • Physicians' Cancer Chemotherapy Drug Manual 2018
    La comanda in aproximativ 4 saptamani
    430.00 lei

    Overview

    Completely revised and updated for 2018, the Physicians’ Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens—both on- and off-label—for the treatment of all the major cancers.

    Features

    §  A specific chapter focused on antiemetic treatment regimens for both acute and delayed nausea/vomiting

    §  Diagrams of drug structures and pathways for many of the agents

    §  A comprehensive discussion of clinical pharmacology, special considerations, indications, and dosages

    §  Covers toxicity and drug–drug interactions

    §  A section on chemotherapy regimens for all major cancers

    §  Provides an overview of the basic principles of cancer drug therapy
    Table of Contents

    Chapter 1: Principles of Cancer Chemotherapy
    Chapter 2: Chemotherapeutic and Biologic Drugs
    Chapter 3: Guidelines for Chemotherapy and Dosing Modifications
    Chapter 4: Common Chemotherapy Regimens in Clinical Practice
    Chapter 5: Antiemetic Agents for the Treatment of Chemotherapy-Induced Nausea and Vomiting

  • 431.00 lei

    Lung cancer is the neoplastic disease with the highest mortality numbers in the world. The disease is very common in industrialized countries. This textbook synthesizes the basic science of lung cancer with state-of-the-art accounts of diagnosis and treat

  • Pediatric Cancer Genetics
    La comanda in aproximativ 4 saptamani
    432.00 lei

    Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Drs. Nathaniel H. Robin and Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children with cancer, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today's available information and guidance in this timely area into one convenient resource.

  • Oncoplastic Breast Surgery
    La comanda in aproximativ 4 saptamani
    48300lei 435.00 lei

    This book presents 50 cases, encompassing a broad range of oncoplastic breast surgeries. Each case is dedicated to a particular surgical technique, using classifications of “good, bad, and ugly” to point out potential pitfalls and to optimize post-surgery results. With the help of more than 500 high-quality illustrations and photos and detailed step-by-step instructions the editors, respected experts in their field, describe the most common procedures.

    Now in its second edition, this comprehensive surgical atlas provides practical guidance for various oncoplastic techniques used in breast conservation surgery and mastectomy with immediate reconstruction.

    The book will be a valuable resource not only for surgeons specialized in breast cancer therapy, but also for general surgeons and gynecologists as well as for plastic and reconstructive surgeons.

  • 48300lei 435.00 lei

    The main objective of this book is to provide radiation oncologists with a clear, up-to-date guide to tumor delineation and contouring of organs at risk. With this in mind, a detailed overview of recent advances in imaging for radiation treatment planning is presented. Novel concepts for target volume delineation are explained, taking into account the innovations in imaging technology. Special attention is paid to the role of the newer imaging modalities, such as positron emission tomography and diffusion and perfusion magnetic resonance imaging. All of the most important tumor entities treated with radiation therapy are covered in the book. Each chapter is devoted to a particular tumor type and has been written by a recognized expert in that topic.

  • 435.00 lei

    There are few publications about drug interactions in chemotherapy and even less about pediatric oncology treatment. For this reason, the present book is intended to offer guidelines about drug interactions for physicians, pharmacists and the other healthcare professionals involved in the chemotherapy of pediatric patients. In this book the reader will have access to a primary introduction for the major diseases in pediatric oncology, followed by the major therapeutic protocols. Following that, the most important drug interactions in pediatric oncology treatment are presented and discussed in detail. Finally, important topics such as Drug-Food Interactions are addressed. Drug Therapy and Interactions in Pediatric Oncology focuses in great detail on the drug interactions in Pediatric Oncohematology and will be an indispensable resource in daily practice for a wide range of health providers.

  • 443.00 lei

    This volume contains the majority of the invited keynote lectures presented by experts at the Third International Conference on Controversies in Tumor Prevention and Genetics on 12-14 February 2004 in St.Gallen, Switzerland. Together, they reveal the late

  • 450.00 lei

     Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.

  • 450.00 lei

    Updated with details on the newest therapies and sporting a new full-color design, this latest edition of Radiation Oncology: Management Decisions continues to offer comprehensive guidance for residents as well as radiation oncologists already in professional practice. You?ll discover the latest treatment plans for numerous cancer sites and tumor types, including the mouth and sinus, gastrointestinal areas, lungs, bones, and blood. Concise, easy-to-read material you can use in a clinical setting immediately with patients! ? Combines comprehensive overviews of basic concepts with the latest radiologic treatment regimens for a wide variety of tumor types and cancer sites. ? Now in full color! Bursting with hundreds of illustrations, figures, and images to illuminate visually important and state-of-the-art techniques. ? Heavily bulleted content format and to-the-point writing style makes content easy to digest and use with patients quickly. ? Chapters that address tumor- or site-specific treatments cover screening, assessment, staging, therapeutic developments, and other key information. ? Features an up-to-date list of commonly prescribed drugs?streamlined for easier reading?and coverage of the latest pain management and palliative treatments. Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities! ? Read directly on your preferred device(s), such as computer, tablet, or smartphone. ? Customize for your language, including right-to-left reading, vertical writing, and enhanced annotation in over 30 languages. ? Easily convert to audiobook, powering your content with natural language text-to-speech. ? Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more.

  • Physicians' Cancer Chemotherapy Drug Manual 2019
    La comanda in aproximativ 4 saptamani
    455.00 lei

    Completely revised and updated for 2019, the Physicians? Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens?both on- and off-label?for the treatment of all the major cancers. Features ? A specific chapter focused on antiemetic treatment regimens for both acute and delayed nausea/vomiting ? Diagrams of drug structures and pathways for many of the agents ? A comprehensive discussion of clinical pharmacology, special considerations, indications, and dosages ? Covers toxicity and drug?drug interactions ? A section on chemotherapy regimens for all major cancers ? Provides an overview of the basic principles of cancer drug therapy

  • 460.00 lei

    Perfect for radiation oncologists, medical physicists, and residents in both fields, Practical Radiation Oncology Physics provides a concise and practical summary of the current practice standards in therapeutic medical physics. A companion to the fourth edition of Clinical Radiation Oncology, by Drs. Leonard Gunderson and Joel Tepper, this indispensable guide helps you ensure a current, state-of-the art clinical practice. Covers key topics such as relative and in-vivo dosimetry, imaging and clinical imaging, stereotactic body radiation therapy, and brachytherapy. Describes technical aspects and patient-related aspects of current clinical practice. Offers key practice guideline recommendations from professional societies throughout - including AAPM, ASTRO, ABS, ACR, IAEA, and others. Includes therapeutic applications of x-rays, gamma rays, electron and charged particle beams, neutrons, and radiation from sealed radionuclide sources, plus the equipment associated with their production, use, measurement, and evaluation. Features a "For the Physician" box in each chapter, which summarizes the key points with the most impact on the quality and safety of patient care. Provides a user-friendly appendix with annotated compilations of all relevant recommendation documents. Includes an enhanced Expert Consult eBook with open-ended questions, ideal for self-assessment and highlighting key points from each chapter. Download and search all of the text, figures, and references on any mobile device.

  • 463.00 lei

    This textbook provides a comprehensive resource for clinicians and researchers regarding immunomodulatory (IMiDS) drugs and their rapidly emerging role in cancer medicine. This new class of anticancer agents has made a tremendous impact on the treatment o

  • 51500lei 463.00 lei

    This textbook focuses on the nascent field of Immunoepidemiology that addresses how differences in immune responses among individuals affect the epidemiology of infectious diseases, cancer, hypersensitivity, and autoimmunity. The idea for the book originated from a course entitled “Immunology for Epidemiologists“ at the Yale School of Public Health. While many fine textbooks are available that address the immunological responses of individuals to pathogens, these provided very little information regarding how immunological variation among populations affects the epidemiology of disease. And yet, it has long been recognized that there is great immunologic diversity among people, which can have a profound effect on the epidemiology of disease. Careful review of the immunologic and epidemiologic literature revealed that there have been relatively few publications concerning immunoepidemiology and that no textbook is available on the subject. This textbook therefore aims to fill this void by providing a much-needed tool to comprehensively and efficiently teach immunoepidemiology. The book includes a section on the basic principles of immunology, and then applies them to particular examples of disease in human populations. The target audience for this text book are Masters of Public Health students. Others who should also find it of interest include PhD students in epidemiology, immunology, medical students, generalists, and specialists in immunology, infectious diseases, cancer, and rheumatology.

    ·  Section I. INTRODUCTION

    ·  1. Introduction to Immunology, Epidemiology, and Immunoepidemiology

    ·  Section II. IMMUNOLOGY BASICS

    ·  2. Organization and Cells of the Immune System

    ·  3. Innate Immunity: Recognition and Effector Functions

    ·  4. Adaptive Immunity: Antigen Recognition by T and B Lymphocytes

    ·  5. Adaptive Immunity: Effector Functions, Regulation, and Vaccination

    ·  6. Disorders of the Immune System

    ·  Section III. IMMUNOEPIDEMIOLOGY BASICS: IMMUNOLOGY OF POPULATIONS

    ·  7. Immunoepidemiology of Selected Components of the Innate and Adaptive Immune Systems

    ·  8. Immunoepidemiology of Immune Dysfunction

    ·  Section IV. IMMUNOEPIDEMIOLOGY OF INFECTIOUS DISEASES AND CANCER

    ·  9. Immunoepidemiology of Mycobacterium tuberculosis

    ·  10. Immunoepidemiology of Human Immunodeficiency

    ·  11. Fungal Immunoepidemiology

    ·  12. Immunoepidemiology of Plasmodium falciparum malaria

    ·  13. Immunoepidemiology of Cancer

    ·  Section V. IMMUNOEPIDEMIOLOGIC INVESTIGATIVE, THERAPEUTIC, AND PREVENTATIVE TOOLS

    ·  14. Modeling Approaches Toward Understanding Infectious Disease Transmission

    ·  15. Vaccines

    ·  16. Immunotherapy for Infectious Diseases, Cancer, and Autoimmunity


  • Immune Checkpoint Inhibitors in Cancer
    La comanda in aproximativ 4 saptamani
    468.00 lei

    Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It's an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. Helps you translate current research and literature into practical information for daily practice. Presents information logically organized by disease site. Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. Consolidates today's available information on this timely topic into one convenient resource.

  • Pulmonary Adenocarcinoma: Approaches to Treatment
    by Horn
    La comanda in aproximativ 4 saptamani
    468.00 lei

    Get a quick, expert overview of the latest treatment and management approaches for adenocarcinoma of the lung, including novel therapeutics in immunotherapy and targeted therapies. This practical title, edited by Dr. Leora Horn, offers succinct coverage of clinically-focused topics and guidelines, making it an ideal resource for practicing and trainee oncologists and other members of the cancer care team. Discusses surgical approaches, molecular testing, adjuvant therapy, first- and second-line therapy, and much more. Helps you translate current research and literature into practical information for daily practice. Consolidates today's available information on this timely topic into one convenient resource.

  • HER2-Positive Breast Cancer
    La comanda in aproximativ 4 saptamani
    468.00 lei

    Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today's available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists. Covers the diagnosis, treatments and targeted therapies, and management of breast cancers that are HER2-positive. Contains sections on background and testing, advanced disease, therapeutics, and toxicity considerations. Includes a timely section on innovative future therapies.

  • 468.00 lei

    This issue of Surgical Oncology Clinics of North America, guest edited by Drs. Caprice C. Greenberg and Daniel E. Abbott, is devoted to Measuring Quality in a Shifting Payment Landscape: Implications for Surgical Oncology. Drs. Caprice C. Greenberg and Daniel E. Abbott have assembled expert authors to review the following topics: Implications of the Affordable Care Act or Surgery and Cancer Care; Repealing the Affordable Care Act and Implications for Cancer Care; Quality Measurement and Pay for Performance; Surgical Collaboratives for Quality Improvement; Big Data and Cancer Care; Cancer Care Delivery Research; Engaging Stakeholders and Patient Partners; Beyond Morbidity and Mortaility - Outcomes that Matter to Patients; Regionalization and its Alternatives; The Economics of the End of Life: Power of Attorney, Palliative Care, Utilization of Hospice; The Accountable Care Organization for Surgical Care; and more!

  • 468.00 lei

    Description:

    For those preparing for certification or recertification in hematology or oncologyHoffman and Abeloff's Hematology-Oncology Review is a single-volume source of authoritative, up-to-date exam preparation. This unique question and answer review helps you succeed on today’s board exams with more than 1,000 board-style questions, answers, and rationales; comprehensive coverage of essential exam topics, and online practice tests.

    • Includes 1,000 board-style questions with answers and rationales explaining both correct and incorrect answers.
    • Covers a broad range of topics compiled by experts in hematology and oncology, including cancer biology and genomics, immunotherapy, hematologic malignancies, solid tumor malignancies, non-malignant hematology, and supportive care.
    • Uniquely designed as both a standalone review and a study companion to Abeloff’s Clinical Oncology and Hematology: Basic Principles and Practice.

     

      Table of Contents

    ·  Copyright

    ·  Dedications

    ·  Contributors

    ·  Preface

    ·  Science and Therapy

    ·  Section 1. Cancer Biology, Genomics, and Immunology

    ·  Chapter 1. Cancer Biology

    ·  Chapter 2. Tumor Immunology

    ·  Section 2. Anti-Cancer Therapies

    ·  Chapter 3. Cancer Chemotherapy

    ·  Chapter 4. Immunotherapy and Pathway Inhibitors

    ·  Part 2. Hematologic Malignancies

    ·  Chapter 5. Acute Myeloid Leukemia and Myelodysplastic Syndrome

    ·  Chapter 6. Myeloproliferative Disorders

    ·  Chapter 7. Chronic Lymphocytic Leukemia, Hairy Cell Leukemia, and Other Chronic Lymphoproliferative Disorders

    ·  Chapter 8. Hodgkin Lymphoma

    ·  Chapter 9. Non-Hodgkin Lymphoma

    ·  Chapter 10. Multiple Myeloma and Other Plasma Cell Dyscrasias

    ·  Chapter 11. T-Cell and Natural Killer Cell Neoplasms and Other Lymphoid Malignancies

    ·  Chapter 12. Hematopoietic Cell Transplantation

    ·  Part 3. Solid Tumor Malignancies

    ·  Chapter 13. Breast Cancer

    ·  Early-Stage Breast Cancer

    ·  Metastatic Breast Cancer

    ·  Premalignant Breast Cancer Conditions and In Situ Disease

    ·  Chapter 14. Lung Cancer

    ·  Non-Small Cell Lung Cancer

    ·  Small Cell Lung Cancer

    ·  Chapter 15. Other Thoracic Malignancies

    ·  Mesothelioma

    ·  Thymoma and Thymic Cancer

    ·  Chapter 16. Head and Neck Cancer

    ·  Chapter 17. Esophageal Cancer

    ·  Chapter 18. Gastric Cancer

    ·  Chapter 19. Pancreatic Cancer

    ·  Chapter 20. Colorectal and Anal Cancer

    ·  Chapter 21. Hepatobiliary Cancer

    ·  Chapter 22. Neuroendocrine, Small Bowel, and Appendiceal Malignancies

    ·  Chapter 23. Prostate Cancer

    ·  Chapter 24. Bladder and Other Urothelial Cancers

    ·  Chapter 25. Renal Cell Carcinoma

    ·  Chapter 26. Germ Cell Tumor

    ·  Chapter 27. Gynecological Malignancies

    ·  Ovarian Cancer and Fallopian Tube Cancer

    ·  Cancer of the Cervix, Uterus, Vagina, Vulva, and Gestational Choriorcinoma

    ·  Chapter 28. Melanoma and Other Skin Cancers

    ·  Chapter 29. Bone and Soft Tissue Sarcoma

    ·  Chapter 30. Unknown Primary Site

    ·  Chapter 31. Malignancies of the Central Nervous System

    ·  Primary

    ·  Metastatic

    ·  Chapter 32. Hereditary Cancer Syndromes

    ·  Part 4. Non-Malignant Hematologic Conditions

    ·  Chapter 33. Coagulation

    ·  Chapter 34. Hematopoietic System Disorders

    ·  Chapter 35. Transfusion Medicine

    ·  Part 5. Survivorship and End of Life Care

    ·  Chapter 36. Pain Control and End of Life

  • 54000lei 473.00 lei

    Covering all aspects of molecular pathology as it relates to the transformation and pathogenesis of cancer, this award-winning volume in the Diagnostic Pathology?series is an expert resource for pathologists at all levels of experience and training, both as a quick reference and as an efficient review to improve knowledge and skills. This easily accessible, point-of-care reference features templated, bulleted content that is generously illustrated with charts, graphs, tables, and color photomicrographs of histology with special stains. It offers a practical, clinical approach to examining how molecular mutations affect common medical diseases and identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies. Provides updated information on molecular mutations in different tumors, including solid tumors and hematopoietic neoplasms, and new targeted therapies geared toward these molecular alterations Discusses now widely used immunotherapy treatments, including how immunotherapy has revolutionized the treatment of many neoplasms such as breast and lung carcinomas and lymphoma Features more than 2,000 annotated images throughout, including H&E stains, immunostains, and FISH images Covers timely topics such as: Recent advances in cancer immunotherapy, specifically in the molecular basis of immunotherapy Newly discovered targeted therapies, including multiple lung carcinoma therapies now considered for patients based on existing mutations to specific genes (KRAS, ALK, BRAF, and ROS) The need for integration of myeloid and lymphoid gene panels due to increased knowledge from next generation sequencing studies of new mutations and the resulting newly developed molecular targets Increased usage of next generation sequencing techniques Changes to hematopoietic tumor details based on revised WHO guidelines Recipient of a 2016 BMA Award: Highly Commended, Pathology (previous edition) Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

    ·  SECTION 1: INTRODUCTION

    ·  Chapter 1: Structure of Chromosomes and Nucleic Acids

    ·  Chapter 2: DNA Replication, Transcription, and Translation

    ·  Chapter 3: Gene Mutations

    ·  SECTION 2: COMMON TECHNIQUES FOR ANALYSIS OF ALTERATIONS IN CHROMOSOMES AND DNA

    ·  Chapter 4: Cytogenetics and FISH

    ·  Chapter 6: Amplification Methods

    ·  Chapter 7: DNA High-Resolution Melting Curve Analysis

    ·  Chapter 8: Sequencing Technologies

    ·  Chapter 9: High-Throughput Methods in Molecular Pathology

    ·  Chapter 10: DNA Methylation Analysis

    ·  SECTION 3: MOLECULAR GENETIC TESTS IN HEMATOPOIETIC TUMORS

    ·  Chapter 11: BCR-ABL1 Fusion Gene

    ·  Chapter 12: PML-RARA Fusion Gene

    ·  Chapter 13: Reverse Transcription PCR for Other Myeloid Leukemia Transcripts

    ·  Chapter 14: FLT3, NPM1, and CEBPA Mutations

    ·  Chapter 15: JAK2 Mutations and Rearrangements

    ·  Chapter 16: MPL Mutations

    ·  Chapter 17: Calreticulin (CALR) Mutations

    ·  Chapter 18: CSF3R Mutations

    ·  Chapter 19: SETBP1 Mutations

    ·  Chapter 20: KIT Mutations

    ·  Chapter 21: IDH1 and IDH2 Mutations

    ·  Chapter 22: Other Mutations and Gene Panel Testing in Myeloid Neoplasms

    ·  Chapter 23: Immunoglobulin Heavy (IGH) Chain Gene Rearrangements

    ·  Chapter 24: T-Cell Receptor Gamma (TRG) and Delta (TRD) Chain Rearrangements

    ·  Chapter 25: T-Cell Receptor Beta (TRB) Chain Gene Rearrangements

    ·  Chapter 26: Southern Blot Analysis of Antigen Receptor Genes

    ·  Chapter 27: EBV-Associated Human Neoplasms

    ·  Chapter 28: MYD88 Mutation

    ·  Chapter 29: NOTCH1 Mutation

    ·  Chapter 30: EZH2 Mutation

    ·  SECTION 4: MOLECULAR GENETIC TESTS IN SOLID TUMORS, BONE AND SOFT TISSUE TUMORS, AND CNS TUMORS

    ·  Chapter 31: ALK Gene Rearrangements and Mutations

    ·  Chapter 32: ROS1 Rearrangements

    ·  Chapter 33: RET Rearrangements

    ·  Chapter 34: FISH for MET Amplifications

    ·  Chapter 35: FISH for ERBB2 (HER2) Gene Amplifications

    ·  Chapter 36: KRAS Mutations

    ·  Chapter 37: BRAF Mutations

    ·  Chapter 38: EGFR Mutations

    ·  Chapter 39: Targeted Hotspot Gene Panel Using Massively Parallel Sequencing (Next-Generation Sequencing)

    ·  Chapter 40: Targeted Hotspot Gene Panel Table

    ·  Chapter 41: MGMT Promoter Gene Methylation Assay

    ·  SECTION 5: MOLECULAR PATHOLOGY OF MYELOID NEOPLASMS

    ·  Chapter 42: Molecular Work-Up of Myeloid Neoplasms

    ·  Chapter 43: Chronic Myeloid Leukemia, BCR-ABL1 Positive

    ·  Chapter 44: Chronic Neutrophilic Leukemia

    ·  Chapter 45: Polycythemia Vera

    ·  Chapter 46: Primary Myelofibrosis

    ·  Chapter 47: Essential Thrombocythemia

    ·  Chapter 48: Chronic Eosinophilic Leukemia, NOS

    ·  Chapter 49: Myeloproliferative Neoplasms, Unclassifiable

    ·  Chapter 50: Mastocytosis

    ·  Chapter 51: Myeloid/Lymphoid Neoplasms With Eosinophilia and Gene Rearrangement

    ·  Chapter 52: Overview and Classification of Myelodysplastic Syndrome

    ·  Chapter 53: Myelodysplastic Syndromes With Single-Lineage Dysplasia

    ·  Chapter 54: Myelodysplastic Syndrome With Ring Sideroblasts

    ·  Chapter 55: Myelodysplastic Syndrome With Multilineage Dysplasia

    ·  Chapter 56: Myelodysplastic Syndrome With Isolated del(5q)

    ·  Chapter 57: Myelodysplastic Syndrome, Unclassifiable

    ·  Chapter 58: Childhood Myelodysplastic Syndrome and Refractory Cytopenia of Childhood

    ·  Chapter 59: Overview of Myelodysplastic/Myeloproliferative Neoplasms

    ·  Chapter 60: Chronic Myelomonocytic Leukemia

    ·  Chapter 61: Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative

    ·  Chapter 62: Juvenile Myelomonocytic Leukemia

    ·  Chapter 63: Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable

    ·  Chapter 64: Overview of Acute Myeloid Leukemia

    ·  Chapter 65: Acute Myeloid Leukemia With t(8;21); RUNX1-RUNX1T1

    ·  Chapter 66: Acute Myeloid Leukemia With inv(16) or t(16;16); CBFB-MYH11

    ·  Chapter 67: Acute Promyelocytic Leukemia With t(15;17); PML-RARA

    ·  Chapter 68: Acute Myeloid Leukemia With t(9;11); MLLT3-KMT2A

    ·  Chapter 69: Acute Myeloid Leukemia With t(6:9); DEK-NUP214

    ·  Chapter 70: Acute Myeloid Leukemia With inv(3) or t(3;3); GATA2, MECOM

    ·  Chapter 71: Acute Myeloid Leukemia (Megakaryoblastic) With t(1;22); RBM15-MRTFA

    ·  Chapter 72: Acute Myeloid Leukemia With Myelodysplasia-Related Changes

    ·  Chapter 73: Acute Myeloid Leukemia, NOS

    ·  Chapter 74: Therapy-Related Myeloid Neoplasms

    ·  Chapter 75: Myeloid Sarcoma

    ·  Chapter 76: Myeloid Proliferations Associated With Down Syndrome

    ·  Chapter 77: Blastic Plasmacytoid Dendritic Cell Neoplasm

    ·  Chapter 78: Overview of Lymphoid Neoplasms

    ·  Chapter 79: Molecular Work-Up of Lymphoid Neoplasms

    ·  Chapter 80: Lymphoma-Associated Chromosomal Translocations

    ·  Chapter 81: B-Lymphoblastic Leukemia/Lymphoma With Recurrent Genetic

     

    ·  Chapter 82: B-Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like (Ph-Like ALL)

    ·  TERMINOLOGY

    ·  EPIDEMIOLOGY

    ·  ETIOLOGY/PATHOGENESIS

    ·  CLINICAL IMPLICATIONS

    ·  Chapter 83: T-Lymphoblastic Leukemia/Lymphoma

    ·  Chapter 84: Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia

    ·  Chapter 85: B-Cell Prolymphocytic Leukemia

    ·  Chapter 86: Splenic Marginal Zone Lymphoma

    ·  Chapter 87: Hairy Cell Leukemia

    ·  Chapter 88: Splenic B-Cell Lymphoma/Leukemia, Unclassifiable

    ·  Chapter 89: Lymphoplasmacytic Lymphoma

    ·  Chapter 90: Monoclonal Gammopathy of Undetermined Significance

    ·  Chapter 91: Plasma Cell Myeloma

    ·  Chapter 92: Follicular Lymphoma

    ·  Chapter 93: Mantle Cell Lymphoma

    ·  Chapter 94: Diffuse Large B-Cell Lymphoma

    ·  Chapter 95: Burkitt Lymphoma

    ·  Chapter 96: T-Cell Prolymphocytic Leukemia

    ·  Chapter 97: Chronic Lymphoproliferative Disorder of NK Cells

    ·  Chapter 98: Aggressive NK-Cell Leukemia

    ·  Chapter 99: Extranodal NK-/T-Cell Lymphoma, Nasal Type

    ·  Chapter 100: Adult T-Cell Leukemia/Lymphoma

    ·  Chapter 101: Intestinal T-Cell Lymphoma

    ·  Chapter 102: Hepatosplenic T-Cell Lymphoma

    ·  Chapter 103: Subcutaneous Panniculitis-Like T-Cell Lymphoma

    ·  Chapter 104: Mycosis Fungoides/Sézary Syndrome

    ·  Chapter 105: Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders

    ·  Chapter 106: Peripheral T-Cell Lymphoma, NOS

    ·  Chapter 107: Angioimmunoblastic T-Cell Lymphoma

    ·  Chapter 108: Anaplastic Large Cell Lymphoma, ALK Negative

    ·  Chapter 109: Anaplastic Large Cell Lymphoma, ALK Positive

    ·  SECTION 7: MOLECULAR PATHOLOGY OF DENDRITIC CELL AND HISTIOCYTIC NEOPLASMS

    ·  Chapter 110: Histiocytic Sarcoma

    ·  Chapter 111: Tumors Derived From Langerhans Cells

    ·  Chapter 112: Interdigitating Dendritic Cell Tumor

    ·  Chapter 113: Follicular Dendritic Cell Neoplasm

    ·  SECTION 8: MOLECULAR PATHOLOGY OF SOLID TUMORS

    ·  HEAD AND NECK, INCLUDING SINONASAL TUMORS AND SALIVARY GLANDS

    ·  Chapter 114: HPV-Associated Head and Neck Carcinomas

    ·  Chapter 115: Head and Neck Mucosal Squamous Cell Carcinoma, Non-HPV Related

    ·  Chapter 116: Important Alterations in Non-HPV-Related Head and Neck Squamous Cell Carcinoma

    ·  Chapter 117: Translocation-Specific Salivary Gland Tumors 1

    ·  Chapter 118: Translocation-Specific Salivary Gland Tumors 2

    ·  Chapter 119: Nasopharyngeal EBV-Related Squamous Cell Carcinoma

    ·  Chapter 120: Other Head and Neck Tumors

    ·  Chapter 121: Papillary Thyroid Carcinoma

    ·  Chapter 122: Follicular Thyroid Carcinoma

    ·  Chapter 123: Poorly Differentiated Thyroid Carcinoma

    ·  Chapter 124: Undifferentiated Thyroid Carcinoma

    ·  Chapter 125: Medullary Thyroid Carcinoma

    ·  Chapter 126: Adenocarcinoma, Lung

    ·  Chapter 127: Squamous Cell Carcinoma, Lung

    ·  Chapter 128: Small Cell Neuroendocrine Carcinoma

    ·  Chapter 129: Mesothelioma

    ·  Chapter 130: Gastric Adenocarcinoma

    ·  Chapter 131: Colorectal Adenocarcinoma and Precancerous Lesions

    ·  Chapter 132: Gastrointestinal Stromal Tumor

    ·  Chapter 133: HNF1α-Inactivated Hepatocellular Adenoma

    ·  Chapter 134: β-Catenin-Activated Hepatocellular Adenoma

    ·  Chapter 135: Inflammatory Hepatocellular Adenoma

    ·  Chapter 136: Hepatocellular Carcinoma

    ·  Chapter 137: Pancreatic Ductal Adenocarcinoma

    ·  Chapter 138: Pancreatic Mucinous Cystic Neoplasm

    ·  Chapter 139: Pancreatic Intraductal Papillary Mucinous Neoplasm

    ·  Chapter 140: Cholangiocarcinoma

    ·  Chapter 141: Testicular Germ Cell Tumors

    ·  Chapter 142: Clear Cell Renal Cell Carcinoma

    ·  Chapter 143: Chromophobe Renal Cell Carcinoma

    ·  Chapter 144: Papillary Renal Cell Carcinoma

    ·  Chapter 145: MiT Family Translocation Renal Cell Carcinomas

    ·  Chapter 146: Wilms Tumor

    ·  Chapter 147: Clear Cell Sarcoma of Kidney

    ·  Chapter 148: Oncocytoma

    ·  Chapter 149: Rhabdoid Tumor of Kidney

    ·  Chapter 150: Urothelial Carcinoma

    ·  Chapter 151: Pheochromocytoma/Paraganglioma

    ·  Chapter 152: Adrenal Cortical Carcinoma

    ·  Chapter 153: Neuroblastoma

    ·  Chapter 154: Adrenal Cortical Adenoma

    ·  Chapter 155: Prostatic Adenocarcinoma, Acinar Type and High-Grade Prostatic Intraepithelial Neoplasia

    ·  Chapter 156: ADH and DCIS (Dysplastic, Premalignant)

    ·  Chapter 157: Ductal Carcinomas

    ·  Chapter 158: Lobular Carcinoma

    ·  Chapter 159: Carcinoma With Medullary Features, Breast

    ·  Chapter 160: Metaplastic Breast Carcinoma

    ·  Chapter 161: Phyllodes Tumors

    ·  Chapter 162: Basal-Like and Triple-Negative Carcinomas

    ·  Chapter 163: Preneoplastic Conditions, Cervix/Vulva/Vagina

    ·  Chapter 164: Squamous Cell Carcinoma, Cervix/Vulva/Vagina

    ·  Chapter 165: Adenocarcinoma, Cervix/Vulva/Vagina

    ·  Chapter 166: Endometrial Intraepithelial Neoplasia

    ·  Chapter 167: Uterine Endometrioid Carcinoma

    ·  Chapter 168: Uterine Serous Carcinoma

    ·  Chapter 169: Clear Cell Carcinoma, Uterus

     

    ·  Chapter 170: Uterine Sarcomas

    ·  Chapter 171: Serous Tumors of Ovary and Fallopian Tube

    ·  Chapter 172: Other Surface Epithelial Tumors of Ovary

    ·  Chapter 173: Sex Cord-Stromal Tumors of Ovary

    ·  Chapter 174: Germ Cell Tumor, Ovary

    ·  Chapter 175: Preneoplastic Conditions, Skin

    ·  Chapter 176: Melanoma

    ·  Chapter 177: Squamous Cell Carcinoma, Skin

    ·  Chapter 178: Basal Cell Carcinoma, Skin

    ·  Chapter 179: Other Skin Conditions

    ·  Chapter 180: Overview of Molecular Pathology of Bone and Soft Tissue Tumors

    ·  Chapter 181: Osteosarcomas

    ·  Chapter 182: Ewing Sarcoma

    ·  Chapter 183: Other Small Round Blue Cell Sarcomas

    ·  Chapter 184: Giant Cell Tumor of Bone

    ·  Chapter 185: Intermediate and Malignant Cartilaginous Tumors of Bone

    ·  Chapter 186: Intermediate and Malignant Myofibroblastic/Fibroblastic Tumors

    ·  Chapter 187: Liposarcomas

    ·  Chapter 188: Muscle Sarcomas

    ·  Chapter 189: Intermediate and Malignant Vascular Tumors

    ·  Chapter 190: Malignant Peripheral Nerve Sheath Tumor

    ·  Chapter 191: Representative Genetic Findings in Bone and Soft Tissue Tumors

    ·  Chapter 192: Rare Sarcomas of Uncertain Differentiation With Specific Molecular Alterations

    ·  Chapter 193: High-Grade Astrocytoma

    ·  Chapter 194: Low-Grade Astrocytoma

    ·  Chapter 195: Pilocytic Astrocytoma

    ·  Chapter 196: Oligodendroglioma

    ·  Chapter 197: Ependymoma

    ·  Chapter 198: Medulloblastoma

    ·  Chapter 199: Choroid Plexus Tumors

    ·  Chapter 200: Meningioma

    ·  Chapter 201: Retinoblastoma

    ·  SECTION 9: QUALITY ASSURANCE AND REGULATORY ISSUES

    ·  Chapter 202: Federal Agencies and Regulation of Laboratories

    ·  Chapter 203: FDA Regulations

    ·  Chapter 204: Proficiency Testing and Accreditation

     


  • 474.00 lei

    This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Edward Snyder and Eric A. Gehrie, with Consulting Editors George P. Canellos and H. Franklin Bunn, will focus on Transfusion Medicine. Topics include, but are not limited to, Pathogen Reduction, Transfusion Reactions-Infectious Complications, Txn Rxn-Non-Infectious Complications, Iron Deficiency and Teen Blood Donors, Advances in RBC Serology, Advances in Immunotherapy, Therapeutic Monoclonal Antibody Effect on RBC Compatibility Testing, Cell Therapy-New Regulations and Standards, Alternatives to Platelet and RBC Transfusions, New Hemostatic Agents, Tx Practices for Children with Cancer, and Relevance of Cold Platelets and WB to the Bleeding Oncology Patient.

  • 474.00 lei

    This issue of Hematology/Oncology Clinics, edited by Dr. Ursula Matulonis, will focus on Ovarian Cancer. Topics include, but are not limited to, Risk factors for ovarian carcinoma; Ovarian cancer pathology; Early detection and prevention strategies for ovarian cancer; Pathogenesis, genetics and genomics of high grade serous cancer; Pathogenesis, genetics and genomics of non-high grade serous cancers; Management and Treatment of newly diagnosed ovarian cancer; Management and Treatment of recurrent ovarian cancer; Treatment of rare epithelial ovarian tumors; Targeting DNA damage response and repair as a therapeutic strategy for ovarian cancer; Mechanisms of drug resistance in ovarian cancer; The status of and targeting the immune system in ovarian cancer: current and future approaches; Antibody drug conjugates; The role of angiogenesis in ovarian cancer pathogenesis and treatment; Management and understanding of acute and long term toxicities of patients with ovarian cancer; and Palliative Care of the advanced ovarian cancer patient.

  • 53100lei 475.00 lei

    This book offers essential information on basic and translational research in gastric cancer, while also illustrating potential opportunities for its application in clinical practice. Gastric cancer is the fourth-most-common cancer globally and the second-leading cause of cancer deaths. It is known to be a heterogeneous disease with varied responses to “one-size-fits-all” treatments. Expanding our knowledge of cancer cell genetics may help us to explore more effective treatments in gastric cancer. The research on molecular mechanisms and its clinical applications, both presented here, will help readers gain an in-depth understanding of gastric cancer and its effective treatment.

    The book’s four sections cover personalized medicine, precise regional therapy, immunotherapy and nanomedicine in gastric cancer. Each part presents the state of art, recent advances and the authors’ experiences. Moreover, several interesting cases are described to demonstrate how gastric cancer patients benefit from translational research. This informative and attractively presented book on precision treatment in gastric cancer, including experimental findings and clinical treatment options, offers a valuable resource for oncologists and graduate students working in the field of gastric cancer.

  • Laparoscopic Colorectal Cancer Surgery
    La comanda in aproximativ 4 saptamani
    53100lei 475.00 lei

    This unique guide describes colorectal surgery procedures using medical terminology and anatomical terms originating from embryology.

    In the last decade, laparoscopic procedures in gastrointestinal surgery have been enhanced and their safety has significantly improved. With the number of cases of colorectal cancer surgery increasing and laparoscopic surgery no longer considered a specialized surgery, the recognition of the correct anatomy is vital in these procedures. Unfortunately, however, the understanding of clinical anatomy is frequently separate from that of basic surgical concepts. Initially, the dissecting layer should be presumed to derive from the fascial anatomy based on embryological recognition. Furthermore, the techniques currently being used by surgeons should be described in sufficient detail and the appropriate anatomical terms should always be used. In view of this, this valuable monograph benefits gastrointestinal surgeons and general surgeons who are involved in the treatment of colorectal cancer.

  • 85400lei 480.00 lei

    With the advent of computer technology and medical imaging, treatment planning in radiation oncology has evolved from a way of devising beam arrangements to a sophisticated process whereby imaging scanners are used to define target volume, simulators are used to outline treatment volume, and computers are used to select optimal beam arrangements for treatment. As such, this book is designed to provide a comprehensive discussion of the clinical, physical, and technical aspects of treatment planning. The intent of Treatment Planning in Radiation Oncology is to review these methodologies and present a contemporary version of the treatment planning process. --NEW Each chapter in the previous edition will be updated to the state-of-the-art in the field --NEW For the first time book will be in 4-c with companion solution site and image bank. --NEW Seven new chapters have been added (Treatment Simulation, Treatment Planning Algorithms Protons, SBRT, Electron Beam Therapy, Proton Beam Therapy, Normal Tissue Tolerance, GYN Malignancies) --NEW The most important areas of updates of existing material ar: e 3-D CRT, IMRT, IGRT, and treatment plan evaluation --Emphasizes the modern treatment planning process including physics as well as clinical radiation oncology --Khan is a very well respected leader in this field; his co-editors and contributors are 1st-class. --Takes a total team approach, including the radiation oncologist, medical physicist and dosimetrist

  • 495.00 lei

     Ediția a opta a Manualului AJCC de Stadializare a Cancerului reprezintă un compendiu al tuturor informațiilor disponibile referitoare la stadializarea tumorilor maligne ale adultului pentru toate localizările anatomice vizate. Acest volum constituie rezultatul cooperării dintre Comitetul Unit American pentru Cancer (AJCC) și Comitetul TNM al Uniunii pentru Controlul Internațional al Cancerului (UICC), fiind un material esențial utilizat de medici, pentru a facilita descrierea și raportarea uniformă a bolilor neoplazice. Sunt cuprinse 12 sisteme de stadializare complet noi, o gamă largă de definiții modificate, iar accentul se mută asupra abordării personalizate a cancerului. Cea de‑a opta ediție a Manualului AJCC, tradusă excelent în limba română, rămâne resursa indispensabilă pentru oncologi, hematologi, radioterapeuți, chirurgi, patologi, radiologi, pentru toți profesioniștii implicați activ în lupta contra cancerului.

     

    De ce un manual de stadializare a cancerului?

    Stadializarea tumorilor maligne joacă un rol esențial în lupta contra cancerului. Manualul AJCC de Stadializare a Cancerului este utilizat de medici și profesioniști din domeniul sănătății din întreaga lume, pentru a facilita descrierea și raportarea uniformă a bolilor neoplazice. Clasificarea corectă și stadializarea afecțiunilor oncologice sunt esențiale pentru un management terapeutic adecvat, pentru evaluarea rezultatelor din cadrul studiilor clinice și reprezintă totodată modelul standard pentru raportarea locală, regională și internațională privind incidența și evoluția cancerului.

     

    Cea dea opta Ediție a Manualului AJCC de Stadializare a Cancerului rămâne standardul indispensabil pentru oncologi, chirurgi, anatomopatologi, radiologi, registratori de cancer și pentru toți profesioniștii din domeniul medical din întreaga lume, fiind asigurat astfel faptul că toți specialiștii care se ocupă de bolnavii de cancer sunt pe deplin pregătiți cu privire la termenii de stadializare a maladiilor oncologice.

  • 55400lei 500.00 lei

     Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics:

    • Cardiac complications in patients receiving cancer therapy

    • The treatment of cancer in patients with cardiovascular disease

    • The treatment of cardiovascular disease in patients with cancer

    When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.

  • 57000lei 500.00 lei

    The AJCC Cancer Staging Manual is used by physicians and health care professionals throughout the world to facilitate the uniform description and reporting of neoplastic diseases. Proper classification and staging of cancer is essential for the physician to assign proper treatment, evaluate results of management and clinical trials, and to serve as the standard for local, regional and international reporting on cancer incidence and outcome.


    Significantly expanded and developed by international disease site expert panels, the Eighth Edition AJCC Cancer Staging Manual brings together all the currently available knowledge on staging of cancer at various anatomic sites. In this edition, evidence-based TNM staging is supplemented, as appropriate, by selected molecular markers and newly acquired insights into the molecular underpinnings of cancer. This edition features 12 entirely new staging systems, a wide range of changed or new staging definitions, and a refined emphasis on a personalized-medicine approach. To enhance the print and electronic usability of the cancer staging forms, they are now available exclusively for access and downloading at www.cancerstaging.org.

    The Eighth Edition AJCC Cancer Staging Manual remains the gold standard reference for oncologists, surgeons, pathologists, radiologists, cancer registrars and medical professionals world-wide to ensure that all those caring for cancer patients are fully versed in the language of cancer staging.

  • 57100lei 510.00 lei

    • A globally relevant and comprehensive text with an easy-to-update online version in order to keep pace with new developments in this rapidly changing field.
    • Written by an international team of co-editors, with chapters arranged in accordance with the widely accepted WHO classification of tumour subtypes.
    • A comprehensive overview of each of the tumour subtypes, with management plans for both adult and paediatric populations.

    Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuro-Oncology covers the pathophysiology, diagnosis, classification, and management of tumours of the nervous system. The book provides a comprehensive overview of tumour subtypes, in accordance with WHO classifications, along with management plans for adult and paediatric populations. The international team of co-editors ensures that expert commentaries on existing and wide-reaching diagnostic and treatment guidelines (including NCCN and ESMO) are accessible by a global audience.

  • 518.00 lei

    The pituitary gland is an important one since it controls several of the other hormone glands such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth, or tumor in this gland and they are the subject of very active clinical and patholog

  • 520.00 lei

    Handbook of Supportive and Palliative Radiation Oncology serves as a practical tool and rapid reference to assist radiation oncology practitioners in direct patient care with common palliative care issues. Containing the most recent advances in translational palliative care research, each chapter is organized in a succinct fashion to discuss major symptom burdens, suggested assessment, and various management options. Each symptom and disease section is written to be a rapid, practical guide for clinicians on the floor.

    The book starts with general approaches in palliative radiation oncology that are followed by a section that focuses on common symptoms in palliative care and their management. The next section of the book is devoted to site and disease-specific evaluation, intervention, and management.

    This handbook provides general guidelines and management recommendations for common clinical vignettes encountered by palliative radiation oncology practitioners and supported by palliative radiation oncology research. Concise references are cited to support treatment recommendation.



    • Provides a quick reference for the busy clinician
    • Details standard of care resources for researchers of palliative and supportive care
    • Contains updated standards of care for palliative medicine and a list of common medications and dosages
    • Includes a comprehensive index by symptom and condition to facilitate quick reference

  • 527.00 lei

    An authoritative work that provides a detailed review of the current status of practice and research in cancer prevention and control – an essential reference guide and tool for primary care physicians, the research community and students. Written as a collaborative work by the faculty of the nationally-renowned Cancer Prevention and Control Program at the Arizona Cancer Center, this book harnesses the expertise of researchers, investigators and clinicians in cancer prevention and control, to provide insights into this field for the benefit of nonspecialists.

  • 62000lei 540.00 lei

    This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearance in patients with nodal metastasis, and the role of axillary surgery. Attention is also given to locoregional treatment after preoperative systemic therapy. Because therapeutic impact differs depending upon biological characteristics such as tumor subtype, local therapy should be based both on tumor biology and on therapeutic response in parallel. Associated translational research and mathematical prediction tools such as nomograms also are introduced. This book provides the essence of primary breast cancer care, particularly its individualization with novel therapeutic concepts and strategies, and will greatly benefit physicians and clinical investigators in breast cancer institutions.

  • Cancer Epidemiology Volume 2, Modifiable Factors
    La comanda in aproximativ 4 saptamani
    60000lei 540.00 lei

    Provides a detailed analysis of the study of genes and environments and their interaction and how the use of population sciences facilitates translation and application of new discoveries ·Delves into inherited genetic susceptibility as well as epigenetics and the risk of cancer ·Presents the use of genomics as the latest tool in translational epidemiology ·Examines how cancer epidemiology plays a role in public health policy ·Provides the latest information on modifiable factors in cancer epidemiology: disparities, lifestyle, energy balance and physical activity, smoking and alcohol intake ·Studies how host susceptibility factors such as race and ethinicity influence the risk of cancer ·Details the role of novel technologies and methodologies in unlocking the mysteries of interactions of gene and environment to early detection and intervention of cancers ·Covers the role of cutting-edge technology in predicting genetic mutation caused by gene and environment ·Provides comprehensive information on the epidemiology of organ specific cancers.

    Oferta speciala!!! 600 lei  540 lei

  • 60100lei 540.00 lei

     This unique book deals with both inflammation and cancer in a single source of publication. They are seldom grouped together although it has been known that both diseases are closely associated, particularly in the gastrointestinal tract and liver. As the book touches on two such major areas of diseases in humans, it should be of interest to a wider audience of researchers and readers. It is noted that the book combines the effort of both basic scientists and clinicians from different countries with extensive experiences in molecular biology and clinical practice to unveil the most updated picture of the pathogenesis and therapeutic strategies in the treatment of inflammation and cancer in the digestive tract. In this regard, potential pathogenic modulators and also therapeutic options are widely discussed. These types of information would definitely broaden our knowledge in better understanding these diseases.

  • 60000lei 540.00 lei

    Provides a detailed analysis of the study of genes and environments and their interaction, and how the use of population sciences facilitates translation and application of new discoveries ·Delves into inherited genetic susceptibility as wells as epigenetics and risk of cancer ·Presents the use of genomics as the latest tool in translational epidemiology ·Examines how cancer epidemiology plays a role public health policy Population studies and epidemiology facilitate the discovery of genetic and environmental determinants of cancer and the development of new approaches to cancer control and prevention, therefore they play a central role in the creation of health policies. Cancer Epidemiology compiles areas of research which cover etiological factors or determinants that contribute to the development of cancer and describe the the latest technologies in cancer epidemiology. In Volume 1, Host Susceptibility Factors, leading experts provide chapters on cancer incidence, prevalence, mortality and surveillance, methods, technologies and study design in cancer epidemiology as well as host susceptibility factors in cancer epidemiology. Although a non-standard volume of the highly successful Methods in Molecular Biology™ series, this comprehensive text retains the commitment of the series to collecting the kind of detailed, up-to-date information and implementation advice that is crucial for getting optimal results.

    Oferta speciala!!! 600 lei  540 lei

  • 540.00 lei

    Bone Cancer, 2nd Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases - from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases. Presents a comprehensive, translational source for all aspects of primary bone cancer and bone metastases in one reference work Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays

  • 66800lei 555.00 lei

    The latest, groundbreaking addition to the Advances in Surgical Pathology series, Breast Cancer offers a thorough overview of the disease and the most recent data and technologies used in breast cancer surgery and diagnosis. Whether you’re a new or experienced pathologist or oncologist, or prepping for boards or certification, this is an irreplaceable volume.
     
    Key Features:

    • NEW and updated information on molecular subtypes, predictive and prognostic markers, premalignant and precursor lesions.
    • Coverage of topics including: intraductal papillary carcinoma and variants; microinvasive carcinoma; invasive micropapillary carcinoma
    • More than 250 full-color photos and ultrasound images illustrate the content
    • Special focus on the convergence of pathology and radiology
    • Chapters cover areas including: cytology; imaging and gross features; histology; differential diagnosis; immunohistochemistry; pathogenesis; and molecular genetics of each cancer type

  • 64200lei 562.00 lei

    This volume comprehensively reviews oncology in the precision medicine era of personalized care, latest developments in the field, and indications and clinical trials for the treatment of cancer with targeted therapies, immunotherapy, and epigenetic modulators. It thoroughly addresses concerns of various types of cancers including cancers of the head and neck, lung, colon, esophagus, bladder, pancreas, and breast; melanoma; multiple myeloma; hepatocellular carcinoma; renal cell carcinoma; and sarcomas. It is organized and written in a format that is easy to follow for both clinicians and non-clinical scientists interested in personalized medicine. Chapters cover the identification of the clinical problem and summary of recent findings, tumor biology and heterogeneity, genomics, examples of simple and complex cases, biological pathways, future clinical trials, and financial considerations. Oncology in the Precision Medicine Era: Value-Based Medicine will serve as a useful resource for medical oncologists and healthcare providers tailoring medicine to the needs of the individual patient, from prevention and diagnosis to treatment and follow up.

    ·  1. Healthcare Perspective

    ·  2. Lung Cancer

    ·  3. Esophageal and Gastric Cancer

    ·  4. Sarcomas

    ·  5. Multiple Myeloma

    ·  6. Pancreatic Cancer

    ·  7. Colon Cancer

    ·  8. Renal Cell Carcinoma

    ·  9. Prostate Cancer

    ·  10. Bladder Cancer

    ·  11. Molecular Testing in Ovarian Cancer: Recommendations and Treatment Considerations

    ·  12. Genomic Cancer Risk Assessment

    ·  13. Triple-Negative Breast Cancer

    ·  14. Melanoma

    ·  15. Digital Patient Engagement and Social Media

    ·  16. Hepatocellular Carcinoma

    ·  17. Treatment Strategies in Head and Neck Cancers

    ·  18. Primary Central Nervous System Tumors

    ·  19. Lymphoma


  • Laparoscopic Gastrectomy for Cancer
    La comanda in aproximativ 4 saptamani
    62500lei 575.00 lei

     The first laparoscopy-assisted gastrectomy for gastric cancer was performed in Japan in 1991. In the ensuing 20 years, at first through a process of trial and error, then through the sharing of master surgeons’ accumulated experience, the procedure has been honed and refined to its current high level. From the beginning, it soon became evident that this much less invasive form of gastrectomy, in comparison with traditional open surgery, led to improved quality of life for postsurgical patients, and use of the procedure spread rapidly among gastric surgeons.  Early on, however, there were calls for the establishment of standard techniques and procedures to be followed, with a recognized need to improve the level of safety and the quality of lymph node dissection for local control in cancer treatment. Toward that end, the Laparoscopy-Assisted  Gastrectomy Club  was formed in 1999. In the following year, because both Japan and Korea experience a high rate of gastric cancer, specialists from those two nations came together to form the Japan–Korea  Laparoscopic  Gastrectomy  Joint Seminar, to facilitate and encourage the exchange of vital information. The result has been to achieve an evolving consensus among specialists in the field of endoscopic surgery in Japan and Korea with expertise that can be shared worldwide. A compilation of the current state-of-the-art is now presented in this volume, with accompanying DVD, which will be of great value to all endoscopic surgeons who perform laparoscopic gastrectomy.

  • 575.00 lei

    Written by an international team of authors the Oxford Textbook of Communication in Oncology and Palliative Care integrates clinical wisdom with empirical findings. It draws upon the history of communication science, providing the reader with a comprehensive curriculum for applied communication skills training.

    An essential resource, the Oxford Textbook of Communication in Oncology and Palliative Care is filled with tips and strategies for effective communication about difficult and challenging communication. In focusing on cancer and the end-of-life, it deals with the existential and spiritual challenges found across all of medicine, providing deep insights into what is at stake and how clinicians might optimally respond. This authoritative and wide-ranging book provides clinicians with state-of-the-art and evidence-based guidelines to achieve effective, patient-centred communication in the clinical settings of oncology and palliative care.

    Thoroughly revised and updated, this new edition includes sections on the curriculum for nurses, the core curriculum, and an introductory section on communication science. The chapters embrace specialty issues across the clinical disciplines, from enrolling in clinical trials, working in teams, and discussing genetic risk, to talking about sexuality, infertility, and intercultural issues. An educational perspective is also provided, with chapters covering communication skills training, how to evaluate courses, and international models of training.

  • 66000lei 581.00 lei

    ​This book provides an up-to-date and detailed overview of diagnostic and management strategies for rectal cancer. It includes chapters focusing on recent diagnostic modalities such as technical advances, the role of magnetic resonance imaging (MRI), immunology, and histopathology, as well as the latest surgical techniques for the management of rectal cancer. It also discusses the role of adjuvant, neo-adjuvant and non-operative approaches. Further, it presents the recent guidelines of prevention and early diagnosis, as well as current and future diagnostic and staging work-up, clearly and concisely, linking each topic to the therapeutic options arising from the staging. A large part of this multifaceted book is devoted to the in-hospital care of rectal cancer patients, from the fast-track procedures and enhanced recovery systems to detailed descriptions of the available surgical techniques, including salvage situations, accidents, complications and their treatment.

    ·  1. Technological Advances in Management of Colorectal Cancer

    ·  2. Magnetic Resonance Imaging (MRI) in Rectal Cancers

    ·  3. Staplers in Colorectal Surgery

    ·  4. Total Mesorectal Excision (TME) in Rectal Cancer

    ·  5. Neo-Reservoirs in Rectal Cancer

    ·  6. Pathology in Colorectal Malignancy

    ·  7. Nucleotide Excision Repair (NER) and Role in Colorectal Carcinogenesis

    ·  8. Laparoscopy in Colorectal Cancer

    ·  9. Extralevator Abdominoperineal Excision (ELAPE) in Rectal Cancer

    ·  10. Natural Orifice Transluminal Endoscopic Surgery (NOTES) in Rectal Tumors

    ·  11. Enhanced Recovery After Surgery (ERAS) in Colorectal Surgery

    ·  12. Neoadjuvant and Adjuvant Therapy for Rectal Cancer

    ·  13. Non-operative Management for Rectal Cancer


  • 65200lei 585.00 lei

    This book focuses on early diagnosis and multidisciplinary treatment, which is the key to preventing the occurrence of the liver metastases in colorectal cancer, and to increasing the resection rate of the liver metastasis foci and the 5-year survival after surgery.

    This book is divided into five parts: the introduction, basics, diagnosis, treatment and prevention. It has 20 chapters in total, covering the latest advances in colorectal cancer liver metastases epidemiology, pathogenesis, molecular diagnostics, marker screening, imaging technology, surgery, chemotherapy and prevention, etc. It provides professionals with up-to-date and comprehensive information on colorectal liver metastases. This book is relevant for senior surgeons and physicians working in oncology, general surgery, chemotherapy, digestive medicine, liver medicine and hepatic surgery.

  • 70100lei 600.00 lei

     This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular.  Disease-specific chapters provide guidelines and concise knowledge on CTV selection and delineation and identify aspects that require the exercise of caution during treatment planning. The treatment planning techniques unique to proton therapy for each disease site are clearly described, covering beam orientation, matching/patching field techniques, robustness planning, robustness plan evaluation, etc. The published data on the use of particle therapy for a given disease site are also concisely reported. In addition to fully meeting the needs of radiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists,  and radiation therapists.

  • 69700lei 605.00 lei

    Covering the history of breast cancer, theory of radiofrequency ablation (RFA), resection of carcinoma, imaging before and after non-surgical ablation therapy and quality of life, this book focuses on extensive breast-conserving treatment for the preservation of a cosmetically acceptable breast. It investigates the feasibility of percutaneous, minimally invasive techniques to ablate breast tumors and several modalities such as cryosurgery, laser ablation, thermoablation and high-intensity focused ultrasound. Non-surgical Ablation Therapy for Early-stage Breast Cancer centers on RFA and provides insights into cryoablation and focused ultrasound surgery. 
    RFA has been shown to be effective for treating tumors in many types of tissue, including liver, bone, brain, kidney, pancreas and prostate. As such this book is a valuable resource for breast and general surgeons, radiation oncologists and medical oncologists in all areas. The extensive discussions enable scholars to gain radiological expertise and a basic understanding of molecular biology, leading to better surgery without scalpels.

    Table of contents (20 chapters)

    • Introduction

      Kinoshita, Takayuki

      Pages 1-10

    • Evolution of Operative Methods in Japan

      Ikeda, Tadashi

      Pages 11-18

    • New Trends and Development in Breast Surgery

      Shigekawa, Takashi (et al.)

      Pages 19-28

    • A Theory of Radiofrequency Ablation (RFA)

      Jimbo, Kenjiro (et al.)

      Pages 29-37

    • RFA of Breast Cancer: Criteria and Procedure

      Wada, Noriaki

      Pages 39-52

    • RFA of Breast Cancer: Technique 1, Requisite Skills and Pitfalls to Avoid

      Fujisawa, Tomomi

      Pages 53-63

    • RFA of Breast Cancer: Technique2, Knack and Pitfall

      Ito, Toshikazu

      Pages 65-76

    • Histopathological Evaluation of the Therapeutic Effect of RFA for Early Breast Cancer

      Tsuda, Hitoshi (et al.)

      Pages 77-88

    • Importance of Breast Imaging Before and After RFA Therapy

      Nakamura, Rikiya (et al.)

      Pages 89-103

    • Cosmetic Evaluation of RFA

      Fujisawa, Tomomi

      Pages 105-112

    • RFA of Breast Cancer: A Multicenter Retrospective Analysis

      Ito, Toshikazu

      Pages 113-117

    • RFA with a Cool-Tip Electrode in Early Breast Cancer

      Kinoshita, Takayuki

      Pages 119-131

    • RFA with a LeVeen Needle Electrode in Early Breast Cancer

      Imoto, Shigeru

      Pages 133-141

    • RFA of Early Breast Cancer Followed by Delayed Surgical Resection

      Ohtani, Shoichiro

      Pages 143-153

    • RFA of Early Breast Cancer Without Resection

      Takahashi, Masato

      Pages 155-161

    • Prospective Study of RFA of Early Breast Cancer Without Resection

      Asaga, Sota (et al.)

      Pages 163-171

    • MRI-Guided Focused Ultrasound Surgery of Breast Cancer

      Furusawa, Hidemi

      Pages 173-181

    • Ultrasonography Guided Nonsurgical Cryoablation for Small Breast Cancer

      Fukuma, Eisuke

      Pages 183-198

    • Importance of Breast Imaging Before and After Nonsurgical Ablation Therapy

      Tozaki, Mitsuhiro

      Pages 199-209

    • Future and Development of Nonsurgical Ablation of Breast Cancer

      Mitsuyama, Shoshu

      Pages 211-224

  • 65000lei 610.00 lei

    Offering practical approaches to common clinical problems, Gynecologic Radiation Oncology: A Practical Guide compiles the extensive clinical experience of Drs. Patricia J. Eifel and Ann H. Klopp from MD Anderson Cancer Center into one user-friendly volume. This reference addresses practical aspects of the field:  how to evaluate the role of radiation therapy in various clinical settings, how to explain the rationale for treatment recommendations to referring physicians and patients, when and how to apply various external beam and brachytherapy techniques to address specific clinical problems, and how to monitor and manage patients during and after treatment.  The book focuses on the following items, which can have immediate application to the treatment of patients with gynecologic cancers.


    Key Features:

    ·          Addresses the techniques, methods, and challenging decisions that characterize the day-to-day practice of gynecologic radiation oncology.

    ·         Features more than 700 figures and tables that highlight key information – from initial patient evaluation and treatment recommendation, through the process of radiation treatment planning and delivery, to post-treatment monitoring of patients for recurrence and treatment-related side effects.

    ·         Covers sites of origin, the principles of tumor biology, multidisciplinary management, clinical evaluation, radiation therapy treatment planning and delivery, and symptom management, as well as the features of individual disease sites.

    ·         Includes more than 50 case studies that demonstrate how concepts are applied in real-life clinical situations.

    ·         Provides references that are particularly helpful in clinical decision-making, emphasizing important clinical trials, meta-analyses of relevant data and high-quality review articles.

    ·         Explains not only the insights gained from the clinical literature but also the opportunities for misinterpretation, suggesting how trial results can be more accurately applied to everyday clinical practice.

    ·         Uses extensive cross-referencing throughout to help you navigate the text and find related topics quickly.

    Purchase of the print addition includes a bundled interactive eBook, which can be downloaded to your tablet and smartphone or accessed online and includes features such as:

    ·         Complete content with enhanced navigation

    ·         Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web

    ·         Cross-linked pages, references, and more for easy navigation

    ·         Highlighting tool for easier reference of key content throughout the text

    ·         Ability to take and share notes with friends and colleagues

    ·         Quick reference tabbing to save your favorite content for future use

  • 70600lei 620.00 lei

     This concise and handy manual provides straightforward, up-to-date guidance for cardiologists and other practitioners on the management of cancer patients with cardiac problems, whether they be due to the cancer itself or to antineoplastic treatment. Detailed attention is devoted to the various forms of cardiotoxicity associated with chemotherapy and radiotherapy. The drugs commonly responsible for each toxicity are identified and clear advice is offered on monitoring techniques and treatment approaches. In addition, the issue of cardiotoxicity due to cancer treatment in particular patient groups – children, the elderly, and those with pre-existing cardiac disease – is addressed separately, with guidance on when and how antineoplastic (and/or cardiological) treatments should be modified. Further sections describe the correct responses to cardiac problems secondary to the cancer itself, including thromboembolic disorders and electrolyte imbalances, and the diagnosis, treatment, and follow-up of cardiac tumors.  A closing section considers how to improve cooperation between oncologists, cardiologists, and general practitioners to ensure that cancer patients’ cardiovascular needs are met in a multidisciplinary approach.

  • 620.00 lei

    Features · Approaches the topic from a global perspective with particular emphasis on practice in Europe and North America · Uses a multidisciplinary approach, reflecting the varying needs of the palliative care team · Features a new section on the assessment and management of effects of medical treatments as well as a new section on rehabilitation and survivorship · Includes new information on chemotherapy- and radiation therapy-induced emesis, geriatric palliative care, and hormonal therapy and targeted agents · Covers palliative care in less developed nations Summary "…the thoroughness of the text has to be admired. It is an excellent starting point for students of palliative care which makes an important contribution to any library." —British Journal of Hospital Medicine "… covers a plethora of topics ranging from the development of palliative medicine in different countries to clinical topics and bioethics … an excellent palliative medicine resource." —Darrell A. Owens, DNP, University of Washington Medicine in Doody’s Book Reviews The second edition of the Textbook of Palliative Medicine and Supportive Care builds upon the strengths of the previous edition, providing an alternative approach to this ever-growing specialty. In the absence of an international curriculum for the study of palliative medicine, this textbook continues to provide the essential guidance for those either embarking upon a career in palliative medicine or already established in the field. With additional chapters covering all the different aspects of supportive care, the second edition expands upon its unique evidence-based, multi-professional approach and global perspective ensured by the international team of editors and contributing authors. It features an entirely new section on the assessment and management of effects of medical treatments as well as a new section on rehabilitation and survivorship. This edition also contains new material on chemotherapy- and radiation therapy-induced emesis, geriatric palliative care, and hormonal therapy and targeted agents. With an emphasis on providing palliative service anywhere in the world, including the need to provide such care in developing nations, the book is an ideal complement to the narrative approach of other texts on the topic. It is essential reading for all palliative care physicians in training and in practice, as well as palliative and support care nurses and other health professionals on the palliative care team.

  • 627.00 lei

    Filling a gap in the literature, this guide provides expert recommendations and research on carcinoma of an unknown primary site (CUP). Covering the identification, diagnosis, and management of CUP with illustrative and reader-friendly clinical case examp

  • Autophagy Regulation of Innate Immunity
    by Jun Cui
    La comanda in aproximativ 4 saptamani
    71600lei 629.00 lei

    This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers new ideas and strategies for future drugs based on manipulating autophagy, especially selective autophagy mediated by cargo receptors. Providing a comprehensive overview of the autophagy regulation of innate immunity, it is a valuable resource for graduate students and researchers in the fields of immunology, cell biology and translational medicine.


    ·  1. Introduction

    ·  2. Autophagy Regulation of Mammalian Immune Cells

    ·  3. Autophagy in Plant Immunity

    &midd