Practical, up-to-date, and ready-to-apply coverage of more than 1, 000 diseases and disorders




Thoroughly reviews all of obstetrics and gynecology
Focuses on the practical aspects of clinical diagnosis and patient management
Covers pathophysiology when relevant to diagnosis and treatment
Emphasizes disease prevention and evidence-based medicine
Includes more than 500 anatomic drawings, image studies, and diagrams
Completely updated to reflect the latest research and advances
Consistent presentation includes Clinical Findings, Diagnosis, Treatment, and Complications and Prognosis
Quick-access design facilitates use at the point of care
Updated to include the latest screening and management guidelines

About the authors

Alan H. DeCherney, MD is Chief of Reproductive Biology and Medicine Branch at the National Institute of Child Health and Human Development at the National Institutes of Health in Bethesda, Maryland.

T. Murphy Goodwin, MD is Chief of the Division of Maternal-Fetal Medicine in the Department of Obstetrics and Gynecology at the University of Southern California in Los Angeles, California.

Lauren Nathan, MD is Associate Professor in the Department of Obstetrics and Gynecology at the David Geffen School of Medicine at UCLA in Los Angeles, California.

Neri Laufer, MD is Chairman of the Department of Obstetrics and Gynecology at Hadassah University Hospital in Ein Kerem, Jerusalem in Israel.

Table of contents

Chapter 1. Reproductive Basics
Chapter 2. Normal Obstetrics
Chapter 3. Pregnancy at Risk
Chapter 4. General Gynecology
Chapter 5. Gynecologic Oncology
Chapter 6. Reproductive Endocrinology & Infertility
Chapter 7. Contemporary Issues

 The Essential Therapy Guide to Cancer, Hematologic Disorders, and Supportive Care--Updated with the Latest Treatment Regimens

More than 500 treatment regimens

"Hematology-Oncology Therapy," Second Edition is an up-to-date, comprehensive therapy guide that delivers more than 500 treatment regimens in a succinct, uniform manner. The unique tabular design allows you to instantly locate and implement the proper treatment regimen. Supported by the latest practice guidelines, peer-reviewed literature, and the opinion of experts, "Hematology-Oncology Therapy" integrates extensive information that is critical to both office- and hospital-based practice of hematology and oncology.

Hematology-Oncology Therapy is divided into three sections:

Oncology: 
Provides detailed information about the administration, supportive care, toxicity, dose modification, monitoring, and efficacy of commonly used and recently approved chemotherapeutic regimens, drugs, and biological agents

Supportive Care, Drug Preparation, Complications, and Screening: 
Consists of topics commonly encountered in clinical hematology-oncology practice, such as chemotherapy-induced nausea, oncologic emergencies, radiation complications, cancer pain management, cancer screening, and much more

Selected Hematologic Diseases: 
Delivers an authoritative guide to therapy for the principal diseases in consultative hematology

This edition of "Hematology-Oncology Therapy" is enriched by the updating of all chapters as well as the addition of several new chapters; the new "Expert Opinion," which provides recommendations and guidance from experts on the use of treatment regimens; and inclusion of the latest regimens.

Color Atlas & Synopsis of Echocardiography provides you with an encyclopedic, case-based overview of this essential imaging modality. Featuring more than 500 of state-of-the-art cardiac ultrasound images, this unmatched resource examines both the optimal use and limitations of echocardiography in a variety of clinical situations, with an emphasis on the very latest techniques. Unlike traditional echocardiography texts, this Atlas is focused on the role of echocardiography in patient diagnosis and management, as well as in reviewing the indications, contraindications, and interpretation of echocardiographic images. Authored by expert contributors, each topic begins with a clinical case presentation (patient story) and also includes evidence ratings from the combined ACC/AHA/ASE guidelines and full references.
Topics include: Echocardiographic methods used in everyday practice for the diagnosis and management of cardiac patients, from Transthoracic, Transesophageal and Stress Echocardiography to Hand-Carried Ultrasound (HCU) The role of echocardiography in the diagnosis and management of patients with known or suspected coronary artery disease The importance of echocardiography, including Doppler echo, as a method to assess patients with valvular heart disease Echocardiographic assessment of the patient with new onset dyspnea, known or suspected heart failure, and a range of cardiomyopathies The use of echo in pericardial disease Various diseases of the aorta The use of echocardiography in the patient with a stroke or TIA Echocardiographic evaluation of intracardiac masses The role of echocardiography in managing patients with atrial dysrhythmias The expanding role of echocardiography in guiding interventional procedures.

Oferta speciala!!!  630lei  540 lei

1090 RON 981 RON 

The most trusted, all-in-one guide to fetal brain imaging—now in full color. Edited and written by recognized experts, this acclaimed reference is a highly clinical text and visual atlas. It facilitates a thorough comprehension of the normal and abnormal fetal central nervous system—and helps you apply one of the most important advances in modern perinatology: the early detection of central nervous system anomalies. Here, you will find the full spectrum of prenatal sonography tools and insights, from using ultrasound and MRI to diagnose the fetal face, eye, and brain, to the neurobehavioral development of the fetal brain. Featuring a new full-color presentation and an enhanced, reader-friendly design, the third edition of this unmatched guide is completely refreshed to mirror the significant advances made in imaging resolution and three-dimensional Doppler technology. In addition, the book reflects the growing interest in imaging the fetal nervous system as it pertains to the fetal brain.

FEATURES:

• New full-color design and additional figures, tables, and graphs
• New chapter on ventriculomegaly examines the most common presenting sonographic sign of brain pathology
• New chapters on the evaluation of the fetal cortex and posterior fossa shed light on diagnostically problematic areas of the fetal brain
• New chapters highlighting intrauterine insults, intrauterine infections, and metabolic disorders demonstrate the progress being made in areas that have become critical to fetal neuroscans
• Greater emphasis on the use of high frequency and deep penetrating ultrasound transducer probes clearly explain how they can yield high-resolution pictures of the fetal brain and spine
• Latest perspectives on dissemination of 3D ultrasound techniques and magnetic resource imaging are interwoven into individual chapters to encourage their adoption in daily clinical practice
• More detailed examination of imaging the fetal brain is based on leading-edge, peer-reviewed research from around the world
• SI units are included throughout
• Numerous new 2D and 3D ultrasound images and updated literature references contribute to the most current overview available of this dynamic specialty

Malignant episodic (or "breakthrough") pain is a common feature of cancer pain that can have a negative impact on quality of life for both the patient and carer. It is characterized by a periodic increase in pain over background cancer pain and can be bot

 Conținutul acestei cărți include: 
- informații despre sistemului medical german, atribuţiile principale ale medicului, relaţia cu pacienţii și ceilalți medici din echipă; 
- glosar bilingv de cuvinte şi expresii utile în domeniu; 
- detalii despre diferite componente ale activității medicului: anamneza, examenul clinic, solicitarea de investigaţii, servicii, vizita de gardă, scrisoarea medicală.

Here's the most succinct and informative guide to medical education, from the first day at medical school to the post-registration house officer year. Helpful information from a top medical expert is presented in an easy-to-read style making it easy for students to understand the different methods of course assessment plus discussions on the role of information technology and the principles behind the new curriculum in medical education.

In spite of the diverse opportunities to participate in sports, gymnastics and other forms of exercise at the workplace and during leisure time, the number of young people who have pain in the locomotive apparatus of the body is increasing. Apparently, ma

Rien ne vaut un mot d'esprit ! En réunion ou dans un courrier, les grandes citations sont toujours utiles ! En passant de Confucius à Obama, ce guide pratique vous permettra de découvrir les phrases cultes des grandes personnalités qui ont su marquer leur temps, et vous aidera à faire face à toutes les situations de votre vie professionnelle : motiver une équipe, négocier, recruter, lancer une idée, complimenter, faire rire un collègue…

Inflamația este implicată intr o multitudine de procese fiziologice și fiziopatologice. Progresele științifice actuale cu privire la înțelegerea reacțiilor inflamatorii sunt impresionante.  Probabil, următorii ani vor elucida rolul condițiilor inflamatorii asociate cu boli moderne prevalente în societatea contemporană. Fiziologia și fiziopatologia inflamației reprezintă un sprijin util pentru înțelegerea și însușirea informațiilor științifice actualizate despre reacțiile inflamatorii, structurat în nouă capitole.

Ultimul capitol conține întrebări cu răspunsurile incluse, având ca obiectiv, alături de întregul manuscris, să sprijine studenții și medicii să își aprofundeze și să își verifice cunoștințele, să capete încredere în cazul susținerii unor examene, precum și să faciliteze aplicarea unor concepte fiziopatologice în practica clinică.

Înţelegerea mecanismelor imunologice îndreptate împotriva melanocitelor benigne şi maligne reprezintă un subiect relevant pentru cercetare în momentul actual, întrucât creează premisa dezvoltării de noi terapii imunologice atât în melanom, cât şi în vitiligo, cu rezultate promiţătoare.

În practică, reacţiile imunologice antimelanocitare pot fi studiate în diferite situaţii clinice: în vitiligo, unde procesele imunologice sunt supraexprimate; în nevii Sutton, unde mecanismele imunologice sunt adecvate; în melanom, în care imunosupresia locală împiedică de cele mai multe ori fenomenele antitumorale să acţioneze eficient. Lucrarea prezentă reunește multe dintre studiile autoarei referitoare la aceste mecanisme fiziopatologice, realizate și publicate

în ultimii zece ani în teza de doctorat, precum și proiectele postdoctorale și articolele de specialitate. Realizează totodată actualizarea materialelor cu cele mai recente informații din literatura medicală cu privire la: structura sistemului imun cutanat şi a funcţiei principalelor componente ale acestuia; mecanismele prezente în autoimunitate, autoinflamaţie şi imunitatea antitumorală cutanate; reacţiile imunologice îndreptate împotriva melanocitelor benigne şi maligne în vitiligo, în melanom (regresie) și în nevii melanocitari (nevii Sutton).

Having been marketed to millions as a weight-loss solution, the Atkins diet is now presented as a means of preventing type 2 diabetes, a disease whose rates are skyrocketing, thanks to the prevalence of risk factors such as obesity and high lipid and bloo

From the author of Asperger Syndrome and Adolescence comes this helpful guide for parents and teachers of children aged three to seven who suffer from Asperger Syndrome. AS is on the high-functioning end of the autism spectrum and is purported to have aff

Originally published in 1935, this book presents the content of John A. Ryle's inaugural lecture upon taking up the position of Regius Professor of Physic at Cambridge University. This book will be of value to anyone with an interest in the development of medicine and the history of science.

Originally published in 1943, this book presents the content of the Linacre Lecture for that year, which was delivered by Major Greenwood at St John's College, Cambridge. This book will be of value to anyone with an interest in the development of medicine and the history of science.

Originally published in 1940, this volume contains the text of the Linacre Lecture for that year, delivered by bacteriologist W. W. C. Topley. This book will be of value to anyone with an interest in the history of medicine and the history of field studies.

Originally published in 1946, this volume contains the text of the Linacre Lecture delivered on 6 May of that year by Sir Alexander Fleming on the subject of chemotherapy's application to bacterial infections. This book will be of value to anyone with an interest in medical history.

Originally published in 1932, this book presents the content of Sir Walter Langdon-Brown's inaugural lecture upon taking up the position of Regius Professor of Physic at Cambridge University. This book will be of value to anyone with an interest in the development of medicine and the history of science.

Originally published in 1938, this volume contains the text of the Rede Lecture for that year, delivered by Sir Patrick Laidlaw. This book will be of value to anyone with an interest in virology and the history of medicine.

Originally published in 1946, this book presents the content of Sir Lionel Whitby's inaugural lecture upon taking up the position of Regius Chair of Physic at Cambridge University. This book will be of value to anyone with an interest in the development of medicine and the history of science.

Originally published in 1935, this volume contains the text of the fifth Horsley Memorial Lecture, delivered by Sir Walter Langdon-Brown. This book will be of value to anyone with an interest in medical history, particularly the history of the discovery of the endocrine system.

Originally published in 1946, this book presents the content of Sir Lionel Whitby's inaugural lecture upon taking up the position of Regius Chair of Physic at Cambridge University. This book will be of value to anyone with an interest in the development of medicine and the history of science.

Originally published in 1939, this volume contains the text of the Rede Lecture for that year, delivered by Sir Edward Mellanby. This book will be of value to anyone with an interest in the advances in medical science and their social and economic implications.

This book explores the nature and causes of irritable bowel syndrome and outlines the current treatment options. A large section of the book is devoted to the use of Chinese medicine to heal IBS, which has been proven in double-blind studies to have a dra

Asthma has reached epidemic proportions in the Western world, and nobody is really sure why - there are lots of theories, but no real cure for the millions of children and adults who suffer from this life-threatening disease. This book offers information

As part of our What to Do When the Doctor Says series, this book will help people newly diagnosed as well as those long-suffering with the disease to 1) understand the disease, 2) treat the disease, and 3) live with the disease. Number three is most impor

Selected as a Book of the Year by The New York Times, The Economist, Independent, Observer and Mail on Sunday

THE NEW YORK TIMES NUMBER ONE BESTSELLER

SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017

‘Dramatic and precise… [A] thrilling and comprehensive account of what seems certain to be the most radical, controversial and, to borrow from the subtitle, intimate science of our time… He is a natural storyteller… A page-turner… Read this book and steel yourself for what comes next’
Bryan Appleyard, Sunday Times

The Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee.

Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function.

This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.

The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.

Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

L'épilepsie est une maladie fréquente qui affecte environ 500 000 patients en France. Cette pathologie neurologique bénigne dans la grande majorité des cas peut néanmoins avoir des répercussions psychosociales, professionnelles et familiales majeures. Elle demeure souvent méconnue, voire taboue, et peut constituer pour certains patients une source d'ostracisme permanent. Face à cette maladie, les patients épileptiques se sentent parfois mal renseignés et isolés. La connaissance étant la base de la compréhension et de l'acceptation, cet ouvrage est avant tout destiné aux patients épileptiques dont les questions restent en suspens et à leur entourage désireux de les aider et de les soutenir. Constitué à partir de questions simples émanant tout à la fois des patients, de leurs proches et du personnel soignant, il aborde différents domaines de la vie des patients épileptiques concernant la défi nition et la compréhension de la maladie (mécanismes, causes, facteurs facilitants, évolution), les traitements anti-épileptiques à disposition (types de médicaments, effets secondaires, quand et comment les prendre, nécessité ou non de les prendre régulièrement, chirurgie de l'épilepsie) et surtout la gestion de la vie au quotidien (peut-on être enceinte ? peut-on conduire ? faire du sport ? quels sont les métiers recommandés ? à éviter ? quelles sont les aides financières ? etc.).

There are occasions when a story told from a personal viewpoint can illuminate a profession. Alfred Sommer's epidemiological memoir is such a book. Adventurous, illuminating, and thought provoking, "Ten Lessons in Public Health" is more than the story of one man's work. It tells the tale of how epidemiology grew into global health. The book is organized around ten lessons Sommer learned as his career took him around the world, and within these lessons he explains how the modern era of public health research was born. Three themes emerge from Sommer's story: the duty to help your fellow human beings by traveling to places where there are problems; the knowledge that data-driven research is the key to improving public health; and the need to persevere with sensitivity and strength when science and cultural or sociological forces clash. Nothing in this compelling, sometimes controversial, history is glossed over, as the book's goal is to explain when and why public health efforts triumph or fail. Readers will travel to Bangladesh, Iran, Indonesia, South America, and the Caribbean, where they will learn about spreading epidemics, the aftermath of storms, and vexing epidemiological problems. Sommer reveals the inner politics of world health decisions and how difficult it can be to garner support for new solutions. Triumph, tragedy, frustration, and elation await those who set off on careers in public health, and "Ten Lessons in Public Health" is destined to become a classic book that puts the field into perspective.

With so many medical tests and treatments and so much scientific and medical information – some of it contradictory – how can people make the best medical decisions? Most medical decisions, it turns out, are based on common sense. In this short and easy-to-read book, Dr. Phillip K. Peterson explains the ten rules of internal medicine. Using real case examples he shows how following the rules will help consumers make good decisions about their medical care. "Get Inside Your Doctor's Head" providesadvice about such questions as when to seek treatment, when to get another opinion, and when to let time take its course. Turn to the Ten Rules when you are weighing your doctor's recommendations about diagnostic tests and treatments and use them to communicate more effectively with your doctor. As with all rules, the Ten Rules of Internal Medicine have occasional exceptions – and when evidence suggests that you are an exception, the relevant rule should be broken. Follow the Ten Rules to make decisions in the increasingly complicated medical world when you need guidance about health matters for yourself and your loved ones.

For thousands of years -- indeed, for all of human history except for the past 50 to 70 years in Western societies -- plants have been our chief source of medicine. The fascinating story that unfolds in the pages of this book is much more than a catalog o

Polycystic ovarian syndrome is the number one cause of irregular periods and infertility in women. It affects 10% of women worldwide. PCOS is a condition of overproduction of androgens by the ovaries. In essence, the ovaries produce too much testosterone,

We have all experienced itch, whether from insect bites or dry skin, but millions of people worldwide have chronic or even intractable itch. Just like chronic pain, chronic itch interferes with function – even with quality of life. "Living with Itch" offers relief, drawing on the authors' vast knowledge of itch, the suffering it causes, and available treatments. Itch researchers and clinicians Drs. Gil Yosipovitch and Shawn G. Kwatra explain what itch is and the cascade of physiological events that cause us to experience it. They describe the many skin diseases, from atopic dermatitis (also known as eczema) to psoriasis, and conditions like chronic kidney disease, lymphoma, HIV, and neuropathies that cause itch. "Living with Itch" provides information on preventing itch as well as topical and systemic therapies, regardless of what's causing the itch. Patient and parent narratives explain how itch affects their lives and how they cope with a symptom that can, with medical and social support, be managed.

L'hyperactivité chez l'enfant est un problème bien connu du grand public... enfin c'est ce que l'on croit ! En réalité, de nombreuses idées erronées circulent sur cette pathologie, dont l'appellation scientifique est le Trouble Déficit d'Attention avec ou sans Hyperactivité (TDAH). Cette méconnaissance du trouble fait du tort aux enfants et à leurs familles qui peuvent se retrouver isolées et stigmatisées. À travers cent questions, nous proposons ici de faire le tour des principales idées reçues sur le Trouble Défi cit d'Attention/Hyperactivité. Problème de société ? Maladie génétique ? Comment faire le diagnostic et vers qui se tourner ? Que penser du traitement médicamenteux par Ritaline qui a si mauvaise réputation ? Et surtout : que faire au quotidien pour aider au mieux les enfants souffrant de TDAH ? Une aide indispensable pour les parents, mais aussi la famille, l'entourage et tous les professionnels concernés par le TDAH pour comprendre le trouble et y faire face.

Am pornit la drum cu dorinta de a aduce un instrument de lucru care, tinand cont de situatia actuala din Romania, sa delimiteze testarile cu adevarat necesare de cele facultative sau complet inutile. Un alt rol al sau este facilitarea obtinerii unei solutii cat mai rapide si corecte in dilema: este sau nu permis in timpul sarcinii acest antibiotic? Dar acest vaccin?

De ce o asemenea initiativa? Pentru ca nu suntem un popor al regulilor si al masurii in ceea ce facem asa ca avem in acelasi timp:

⁃ gravide ce ajung sa nasca fara sa stie din timp ca sunt infectate cu VHB sau cu HIV astfel incat sa se poata da o sansa in plus sanatatii copiilor lor, dar si gravide suprainvestigate incat rezultatele testelor sunt contradictorii sau imposibil de interpretat

⁃ medici care recomanda gravidelor fara indicatie serologie de Listeria sau alte teste inutile, dar si medici care nu recomanda nicio testare

⁃ gravide care repeta de mai multe ori aceleasi teste intr-un interval de timp de cateva saptamani si ajung de multe ori sa nu mai creada in rezultatele acestora si sa actioneze la intamplare 

⁃ medici care induc gravidei decizia de intrerupere a sarcinii pe baza unei interpretari fanteziste a rezultatelor testarilor recomandate de ei, dar si medici care neglijeaza sa transmita interpretarea acestor rezultate gravidei si sa ii faca recomandarile necesare.

Pe parcursul elaborarii acestui ghid am realizat tot mai mult ca avem un bun prilej de a incerca sa facem din el si un instrument de lucru impotriva utilizarii excesive si/sau eronate de antibiotice in infectiile caracteristice si in cele frecvente la gravida/lauza.

Lasand continutul ghidului sa indeplineasca rolul de instrument de lucru ne-am permis sa evidentiem unele obstacole in calea im­plementarii unei atitudini coerente in acest domeniu medical, sub forma de raspunsuri la cateva intrebari.

 Cand testam?

Suntem inca una dintre acele state ale Uniunii Europene in care primul bilant al unei gravide se mai efectueaza cand travaliul s-a declansat. Despre planning si evaluare preconceptionala vorbim inca rar, iar sarcina este adesea privita drept o intamplare, un dar sau o problema; din pacate, si generalizarea evaluarii initiale a gravidei in primul trimestru ramane un deziderat de atins in anii ce vin.

 Cine recomanda testarile? Cine prescrie antibiotice, care anume si in ce situatii?

La aceasta intrebare un raspuns unic este hazardat: ginecologul? Medicul de familie? Infectionistul? De fapt, raspunsul nu ar mai avea nicio relevanta daca ar exista un consens in privinta a ceea ce este necesar sa fie testat. Este insa evident ca actualul circuit, in care pe fluxul medic de familie – ginecolog – infectionist, de la ultima veriga se poate decide reluarea ciclului pentru testari omise la pasii anteriori sau se ajunge la inlocuirea/intreruperea administrarii unui antibiotic prescris gravidei in mod eronat/excesiv, este nefunctional. 

Ce se testeaza?

in domeniul patologiei infectioase se aplica insa foarte bine regula lui „aici si acum“; de aceea, si testarile pentru infectiile cu potentiala transmitere maternofetala au un continut specific situatiei din fiecare regiune. A recomanda anumite teste „dupa ureche“ si a trimite apoi gravida cu rezultatele la interpretare „la un infectionist“ poate expune la cateva riscuri:

pune in dificultate infectionistul in a furniza interpretari unor testari inutile sau fara semnificatie pentru situatia actuala a sarcinii

expune medicul ginecolog riscului de scadere a credibilitatii in fata gravidei daca infectionistul se vede nevoit sa prescrie teste omise in bilantul initial

 Cine deconteaza testarile?

Nu toata raspunderea in privinta derapajelor acestor testari apartine lipsei de educatie a gravidei in acest domeniu si/sau deficientelor profesionale ale medicului sau curant. De multe ori am intalnit gravide care aveau o lista de teste recomandate si neefectuate; cel mai adesea iti spun – „nu am avut bani ca sa fac aceste analize“.  Daca ne referim doar la testele cu adevarat utile, majoritatea sunt asigurate in mod gratuit pentru toate gravidele din Romania, dar unele nu. De aici se desprind cel putin doua idei:

- necesitatea de a sustine efectuarea gratuita a tuturor acelor teste cu adevarat necesare, beneficiul medical si cel economic fiind cert;

- necesitatea limitarii recomandarilor la testarile justificate, fara a incarca lista de analize cu alte teste inutile dar care costa, ceea ce va determina uneori ca gravida sa renunte la efectuarea oricarui test

Aparitia in limba romana a cartii “Cunoaste – Bucura-te de viata – Traieste mai bine”, carte redactata de prestigiosul Institut de Psihiatrie Sociala din Viena Ludwig Boltzmann, facut celebru de prof. dr. Heinz Katschnig si de prof. dr. Michaela Amering de la Departamentul de Psihiatrie si Psihoterapie al Universitatii de Medicina din Viena, ar trebui sa constituie un eveniment deosebit. Dincolo de aspectul strict profesional, este o carte despre oameni si omenie, un exercitiu uman, care indeamna cu insistenta la efortul de sporire a calitatii vietii, la sanse ce se pot oferi oricaruia, de a se putea bucura mai mult de viata.

The essential guidebook to pregnancy and beyond You're having a baby and starting parenthood- the adventure of a lifetime! Pregnancy The Beginner's Guide is a trusty travel guide for this amazing journey, from conception to birth and beyond. Being pregnant can feel like being in a foreign country- people use words you've never heard of, such as effacement, you have to visit new places, like birthing units, and you don't know what to wear or what's safe to eat. Pregnancy The Beginner's Guide has the answers with lists, Top 10 facts and a helpful translation guide for the new experiences and words you'll encounter.

It follows the progress of mother and baby month-by-month, making it easy for you to use at all stages of your pregnancy and includes special sections for dads that give tips on what to expect and what's expected of them. Pregnancy The Beginner's Guide is a practical handbag-sized handbook for your journey through pregnancy and birth.

Compassionate and comprehensive, Dr. Francis Mondimore's pathbreaking guide has helped thousands of people and their loved ones cope with bipolar disorder. Now in its third edition, "Bipolar Disorder" has been thoroughly updated with new information about

This is synoptic pathology text that summarises both the general and systemic pathology required by medical and other health science students. Although an entirely "stand alone" text, it has its origins in Woolf: Pathology: Basic and Systemic, and it is ideal for exam preparation. As with the parent textbook, the clinical relevance of the pathology is emphasised throughout.

In 1962, Leonard Hayflick created and then froze roughly 800 tiny ampules of what he dubbed WI-38 cells. Each petite glass vial contained between 1.5 million and 2 million cells. Each cell in each vial, once thawed, had the capacity to divide another 40 times. Hayflick had created a supply of cells that, for practical purposes, was almost infinite.
Hayflick’s WI-38 cells would become the first normal, non-cancerous cells available in virtually unlimited quantities to scientists, and, as a result, the best-characterized normal cells available to this day. They would become the basis for vaccines that have immunized hundreds of millions of people worldwide against polio, rubella, rabies, chicken pox, and measles. Today approximately two billion people have directly benefitted from the use of WI-38 and other cell strains created using Hayflick’s methods.WI-38 would also spawn a lifetime feud between Hayflick and his superiors at the Wistar, and an epochal fight with the US government, first over whether the cells were safe to use to make vaccines and then over who owned them.
The Cells and the Scientist combines scientific discovery, rivalry, greed and drama; abortion and vaccine politics; and timely questions about the tradeoff between socially beneficial medical research and the rights of individuals. Remarkably, both Leonard Hayflick and the 83-year-old mother of the fetus that gave rise to WI-38 are still alive. The mother lives near Stockholm. She was not asked permission for the use of her fetus and has never earned a penny from the contribution.
The tale of WI-38 is a profoundly human one, laced with real effects on untold numbers of lives. Consider this irony: cells derived from an aborted fetus have prevented tens of millions of miscarriages that otherwise would have been caused by the rubella virus, which infects foetuses in the womb.

Înainte de a învăța electrocardiogramă trebuie bine înțeles ce așteptăm de la ea; de cele mai multe ori electrocardiograma nu este diagnosticul ci o treaptă spre diagnostic, dar o treaptă ușor de pășit dacă știi să calci. Există evident excepții în ambele sensuri: uneori electrocardiograma este diagnosticul (preexcitația, aritmia etc.), iar alteori nu te ajută cu nimic (de cele mai multe ori dacă încerci să găsești în electrocardiogramă ceea ce nu poate da). Ar fi o eroare să considerați electrocardiograma normală (cel mai dificil traseu pentru studenții la examen) în această categorie; o electrocardiogramă normală spune foarte multe! Și mai rău ar fi dacă, posedând un aparat electrocardiografic cu diagnostic computerizat, v-ați baza pe diagnosticul calculatorului; am consumat în timp mai multă energie corectând diagnosticele calculatorului decât cea consumată pentru analiza “manuala” a traseului.

Electrocardiograma este o reprezentare grafică a unui fenomen care se descrie vectorial și care pornește de la câteva axiome (datorate marelui Einthoven); majoritatea acestor axiome au fost fizic infirmate sau modificate în timp. Morala acestei constatări este că valoarea electrocardiogramei stă în comparație (fie că ne referim la traseele anterioare ale pacientului, fie ale altor pacienți cu aceeași condiție sau în lipsa lor, cu mai mică valoare, la modelul învățat despre cum trebuie să arate electrocardiograma în condiția dată). Obișnuiesc să recomand studenților mei să abordeze un traseu electrocardiografic în două etape: întâi să privească ca la un tablou și să-și facă o impresie generală, intuitivă, apoi să o uite pentru moment și să reevalueze sistematic traseul (ritmul atrial, conducerea atrioventriculară, depo- larizarea ventriculară, faza de repolarizare etc.) considerând mereu derivațiile sincrone împreună pentru a-și crea o imagine spațială. La cei pe care mi i-am apropiat și au avut răbdare cu mine (și reciproc) lucrurile au funcționat. Iar această metodologie trebuie aplicată indiferent că traseul pare simplu sau dificil. De altfel această terminologie este foarte subiectivă și ține mai mult de interpret decât de traseu. Nu o dată mi s-a cerut să prezint doar trasee „foarte interesante” (citește complicate) și am avut surpriza să constat cât de bine se descurcă unii la probleme delicate și cum se poticnesc la cele simple. Orice traseu electrocardiografic, cât de simplu, poate fi informativ pentru situația pacientului și valoros pentru învățare.

A gripping tale that traces medicine's extraordinary history Kill or Cure tells the riveting history of medicine from chipping holes in skulls to the latest gene therapy and revolutionary cancer treatments. Compelling stories of drama and detective work reveal the trial and error behind man's endless search for cures to diseases and how lucky we are to have the medicines we do today. Uncover the gripping and sometimes gruesome life and death tales behind the medical advances that we take for granted through key figures' diaries and notebooks, showing you discoveries through the eyes of the people who were there at the time. Plague and other global epidemics, the roots of psychiatry and the arrival of robot surgeons are brought to life, with maps, timelines and stunning images ranging from Roman surgical instruments and medieval bloodletting to artificial hearts and the latest scanners. Written by Steve Parker, a Senior Scientific Fellow of the Zoological Society and author of over 250 books, Kill or Cure is the perfect prescription for anyone interested in the history of medicine, terrible diseases and revolutionary cures.

Das Springer Klinisches Wrterbuch 2007/2008 ist das jngste Mitglied der innovativen medizinischen Wrterbcher des Springer-Verlages. Auf der Basis der umfangreichsten medizinischen Wrterbuchdatenbank, auf der auch das Springer Lexikon Medizin und das Sprin

An illustrated and practical guide written by the experts in baby care. It guides you through each stage, from conception to the first 3 years including advice on pregnancy and labour, developmental milestones, child health and first aid. It lays out information in step-by-step sequences and chronologically to enable quick access.

Bien différents des ouvrages de cours ou de fiches existants, les ouvrages de ' La collection des conférenciers ' sont issus d'une analyse détaillée des annales de l'Internat et des ECN de ces dernières années. Cette collection a pour objectif d'apprendre à l'étudiant en DCEM/DFASM comment utiliser le mieux possible ses connaissances pour réussir les ECN. Elle propose :
- Des conseils méthodologiques généraux.
- Une ou plusieurs fiches par item, traitant sous forme de réponses types les points importants pour les ECN, signalant les zéros aux questions au cours du texte et contenant une liste depoints clés et de mots clés.
- La rubrique "Le mot du conférencier" où l'auteur donne son avis sur le sujet, signale aux étudiants les pièges classiques à éviter, les sujets tombés et 'tombables', et les erreurs et lacunes classiques observées lors des conférences et des concours blancs.
Cette troisième édition, mise à jour, est en parfaite conformité avec le nouveau programme de DFASM (Diplôme de formation approfondie en sciences médicales, BO du 16 mai 2013). Elle traite tous les items de neurologie du programme.

IBS affects almost one in six Americans and is characterized by abdominal pain, bloating, gas, and diarrhea and constipation. Today physicians are better able to diagnose this complex disorder, understand and explain its origins, and develop a treatment plan that effectively meets the individual needs of a patient. Since publication of the first edition of "Making Sense of IBS", diagnosis and treatment of irritable bowel syndrome have changed significantly. Drawing on his many years of experience treating people who have symptoms of IBS, Dr. Brian E. Lacy has greatly expanded the first edition, adding new topics and the latest findings on tests, medications, alternative treatments, dietary factors, and lifestyle. Dr. Lacy explains normal digestion, the causes of IBS, how IBS is diagnosed, and what to expect with treatment. He also explores special topics such as IBS in children and psychological, hypnotherapeutic, and psychiatric therapies. Important new information in the second edition includes: - the roles of fiber, gluten, lactose, and fructose in the development and treatment of IBS - the use of probiotics and antibiotics to treat IBS - similarities and differences between IBS and inflammatory bowel disease (IBD) - the relationship between small intestine bacterial overgrowth and IBS - how to make the most of your visits to a gastroenterologist - lifestyle modifications that can improve symptoms of IBS "Making Sense of IBS" is an essential resource for anyone who has symptoms or a diagnosis of IBS as well as for health professionals who treat people with this complex disorder.

Originally published in 1948, and first delivered as the Fitzpatrick Lectures for 1941 and 1943, this book addresses the early history of medical and social statistics and the numerical method as applied to the phenomena of human society. Greenwood covers the major developments from Graunt and Petty in the seventeenth century to Farr in the nineteenth century as well as the personalities of each of these important figures. This book will be of value to anyone with an interest in the history of medicine.

For thousands of years the human heart remained the deepest of mysteries; both home to the soul and an organ too complex to touch, let alone operate on.

Then, in the late nineteenth century, medics began going where no one had dared go before. The following decades saw the mysteries of the heart exposed, thanks to pioneering surgeons, brave patients and even sacrificial dogs.

In 11 landmark operations, Thomas Morris tells us stories of triumph, reckless bravery, swaggering arrogance, jealousy and rivalry, and incredible ingenuity: the trail-blazing ‘blue baby’ procedure that transformed wheezing infants into pink, healthy children; the first human heart transplant, which made headline news around the globe. And yet the heart still feels sacred: just before the operation to fit one of the first artificial hearts, the patient’s wife asked the surgeon if he would still be able to love her.

The Matter of the Heart gives us a view over the surgeon’s shoulder, showing us the heart’s inner workings and failings. It describes both a human story and a history of risk-taking that has ultimately saved millions of lives.

First published in 1941, this book contains the substance of the Linacre Lecture for that year, delivered by Sir Walter Langdon-Brown at St John's College, Cambridge. It presents a concise account regarding 'the origin of witchcraft from primitive religion and the part it played in the evolution of remedies through the magical phase to empirical success aided by laboratory investigation'. This book will be of value to anyone with an interest in the history of science and the development of medicine.

Living with diabetes is a balancing act. Monitoring blood glucose, food intake, and medication is complicated, so individuals with diabetes need to understand their condition and how best to control it. "The Johns Hopkins Guide to Diabetes" is a comprehe

Almost daily we hear news stories, advertisements, and scientific reports that promise genetic medicine will make us live longer, enable doctors to identify and treat diseases before they start, and individualize our medical care. But surprisingly, a century ago eugenicists were making the same promises. The "Science of Human Perfection" traces the history of the promises of medical genetics and of the medical dimension of eugenics. The book also considers social and ethical issues that cast troublesome shadows over these fields. Keeping his focus on America, science historian Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and sceptically, lest pernicious interests trump our own.

Originally published in 1908, this book presents the content of the Linacre Lecture for that year, which was delivered by the renowned Canadian physician William Osler at St John's College, Cambridge. Illustrative figures are included within the text. This book will be of value to anyone with an interest in Thomas Linacre and the history of medicine.

In this sweeping exploration of the relatively recent obesity epidemic, Michael L. Power and Jay Schulkin probe evolutionary biology, history, physiology, and medical science to uncover the causes of our growing girth. The unexpected answer? Our own evolutionary success. For most of the past few million years, our evolutionary ancestors' survival depended on being able to consume as much as possible when food was available and to store the excess energy for periods when it was scarce. In the developed world today, high-calorie foods are readily obtainable, yet the propensity to store fat is part of our species' heritage, leaving an increasing number of the world's people vulnerable to obesity. In an environment of abundant food, we are anatomically, physiologically, metabolically, and behaviorally programmed in a way that makes it difficult for us to avoid gaining weight. Power and Schulkin's engagingly argued book draws on popular examples and sound science to explain our expanding waistlines and to discuss the consequences of being overweight for different demographic groups. They review the various studies of human and animal fat use and storage, including those that examine fat deposition and metabolism in men and women; chronicle cultural differences in food procurement, preparation, and consumption; and consider the influence of sedentary occupations and lifestyles. A compelling and comprehensive examination of the causes and consequences of the obesity epidemic, "The Evolution of Obesity" offers fascinating insights into the question, Why are we getting fatter?

One baby, one year, one extraordinary project Watch My Baby Grow is a unique pictorial event that unlocks the secret world of the newborn baby. By following the journey of one child and her family, Watch My Baby Grow looks at a baby's developing abilities, from birth, through every key milestone over the course of a year. Written in conjunction with the acclaimed Centre for Brain and Cognitive Development, Watch My Baby Grow takes a scientific approach to a very personal experience, covering every area of a child's development and looks at the world from the baby's point of view. With photos of one baby's development week by week from newborn to 12 weeks, and then monthly up to the age of one year. Plus information and pictures of other babies, with colourful and vivid graphics throughout. Full of eye-opening and helpful information such as the evolutionary reason a baby is unable to make speech-like sounds for 4-5 months, why crying sounds the way it does, the reason that various early abilities and reflexes exist and much more. Watch My Baby Grow takes an inside look into the life of a newborn baby, with a scientific celebration of the changes that occur in a baby, in order to better understand the world of a growing infant.

In the middle of the twentieth century, few physicians could have predicted that the modern diagnostic category of osteoporosis would emerge to include millions of Americans, predominantly older women. Before World War II, popular attitudes held that the

PKU (phenylketonuria) is a genetic disorder that causes severe cognitive impairment if it is not detected and treated with a strict and difficult diet. In a lifetime of practice, most physicians will never encounter a single case of PKU, yet every physician in the industrialized world learns about the disease in medical school and, since the early 1960s, the newborn heel stick test for PKU has been mandatory in many countries. Diane B. Paul and Jeffrey P. Brosco's beautifully written book explains this paradox. The development of state programs for early detection of and treatment for PKU is deservedly considered a great public health success story. Advocates have traded on this success to urge expanded newborn screening, to defend basic research in genetics, and to confront proponents of genetic determinism. When deployed for these purposes, treatment for PKU is typically represented as a simple matter of adhering to a low-phenylalanine diet. In reality, the challenges of living with PKU are daunting. In this first general history of PKU, a historian and a pediatrician explore how a rare genetic disease became the object of an unprecedented system for routine testing. "The PKU Paradox" is informed by interviews with scientists, clinicians, policy makers, and individuals who live with the disease. The questions it raises touch on ongoing controversies about newborn screening and what happens to blood samples collected at birth.

In "The Story Within", authors share powerful experiences of living with genetic disorders. Their stories illustrate the complexities involved in making decisions about genetic diseases: whether to be tested, who to tell, whether to have children, and whether and how to treat children medically, if treatment is available. More broadly, they consider how genetic information shapes the ways we see ourselves, the world, and our actions within it. People affected by genetic disease respond to such choices in varied and personal ways. These writers reflect that breadth of response, yet they share the desire to challenge a restricted sense of what "health" is or whose life has value. They write hoping to expand conversations about genetics and identity – to deepen debate and generate questions. Whether they or their families are affected by Huntington's disease, Alzheimer's disease, cancer, genetic deafness or blindness, schizophrenia, cystic fibrosis, Tay-Sachs, hypertrophic cardiomyopathy, fragile X, or Fanconi anemia, their stories remind us that genetic health is complicated, dynamic, and above all, deeply personal.

 Here is the first textbook to present a practical overview of the basic principles and clinical applications for 3 tesla (3 T) MR imaging. Organized into sections according to anatomical location, each case study is presented in a concise, two-page unit that enables the reader to digest and review the material in small sections. The author describes the situations that dictate the use of 3 T and explains the numerous clinical advantages of this field strength by drawing comparisons to corresponding studies at 1.5 T.

Highlights:

• Case studies from leading international experts covering the breadth of clinical MR
• Recommendations for how to optimize image quality and how to interpret the clinical findings
• Easy-to-follow descriptions of the strengths and limitations of 3 T
• 400 high-quality clinical images and illustrations depicting key concepts
• Discussion of the various pulse sequence approaches

Clinical 3T Magnetic Resonance is essential reading for all radiologists, radiology residents, MR physicists, and MR technologists seeking to master this emerging diagnostic tool.

"Cartea pe care v-o propun este o sinteză a experienţei personale în coroborare cu datele acumulate în literatură, relativ la valoarea diagnostică şi prognostică a electrocardiogramei la pacienţii cu STEMI trataţi cu tehnici de reperfuzie. Scopul cărţii este de a vă convinge de faptul că electrocardiograma a fost, este şi va continua să fie un excelent instrument de evaluare a efectului terapiei de reperfuzie (intervenţională sau trombolitică). Sper să vă conving de faptul că la pacienţii cu STEMI şi terapie de repefuzie o electrocardiogramă bine citită şi interpretată continuă să vă fie cel mai bun prieten şi că, spre deosebire de alte tehnici mult mai sofisticate, costisitoare şi greu de aplicat în practica de rutină, ea nu vă creează niciodată „iluzia“ reperfuziei. Altfel spus, dinamica electrocardiografică poate fi adevăratul „gold standard“ în evaluarea succesului sau insuccesului terapiei de reperfuzie. Traseele electrocardiografice prezentate au fost selecţionate strict de la cei peste 2500 de pacienţi cu STEMI pe care i-am îngrijit şi monitorizat nemijlocit în decurs de peste 25 de ani, fiind vorba fie de pacienţi pe care i-am tratat personal cu trombolitice fie de pacienţi pe care i-am îngrijit imediat după tratamentul intervenţional efectuat de către colegii din Laboratorul de Cardiologie Intervenţională" Dr. Gabriel Tatu- Chiţoiu

Wolfgang Koehler (1887-1967) was one of the founders of Gestalt psychology, the influential school that argues that perception is best understood as an organized pattern rather than as separate parts. This book presents Koehler's statement of Gestalt theo

What is it to be truly human at work? Why do so many people today ache to be more human at work? In this book, Lloyd E. Sandelands unites the metaphysics of Aristotle and Aquinas and the social teachings of the Catholic Church to describe how business leaders can help people in their organizations become more truly and fully human. Being at Work is a much-needed marriage of metaphysical philosophy and managerial common sense.

The Quaker philanthropist Samuel Tuke (1784–1857) was the grandson of William Tuke, the founder in 1796 of the Retreat at York, a pioneering asylum for the insane which championed compassionate care and the abolition of physical restraints. Samuel succeeded his grandfather in the management of the Retreat in 1822, but before that was already active in promoting its principles of humane treatment, and publicising the appalling conditions in which 'pauper lunatics', whose families could not afford better care for them, were confined. The publicity generated by his pamphlets and letters to newspapers drew public attention to the problem, and led to a reforming Yorkshire magistrate inviting Tuke to advise on the building of a new asylum at Wakefield. This 1815 book of 'practical hints' was intended to guide the potential architects to offer both inmates and attendants an environment which promoted physical and mental health.

The surgeon Thomas Pettigrew (1791–1865) was interested in all aspects of antiquity. He gained fame in society through his mummy-unwrapping parties, and his History of Egyptian Mummies is also reissued in the Cambridge Library Collection. His interest in the early history of medicine is evidenced by this edition of a work by John Hall, which was published by the Percy Society in 1844. Hall was a surgeon, born 1529/30, who published this work in 1565 as an appendix to his translation of the work of the thirteenth-century surgeon Lanfranc of Milan. Little is known about Hall except that he practised medicine in Maidstone, Kent, and had published acrostic verses. He was vociferous in his indignation against fraudulent medicine, and this work describes nine incidents where quacks, both male and female, had visited Maidstone and offered miraculous cures to the gullible: Hall himself was involved in prosecuting some of them.

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Comment faire simple en neurologie clinique des premières années de la vie ? Les agressions périnatales surviennent sur un cerveau en voie de développement rapide. L'expression neurologique de ces pathologies est donc changeante, en particulier dans le domaine neuromoteur, au cours des deux premières années. Il faut donc des repères précis pour aider le clinicien à identifier les déviations possibles à chaque étape du développement. Pour ce faire, nous avions proposé dans une première édition publiée en 1998 un instrument unique applicable de la naissance à 6 ans, avec un répertoire technique, des instructions pour le codage, des réponses selon l'âge et une grille d'évaluation. Après 10 ans d'utilisation de cet instrument en recherche clinique, le contenu de cette deuxième édition s'est enrichi: - les résultats obtenus ont permis, à l'âge corrigé de 2 ans, d'identifier le spectrum des anomalies neuromotrices allant de la paralysie cérébrale incapacitante (IMOC) aux signes plus mineurs ; - cette catégorisation a montré des corrélations significatives avec la fonction cérébrale évaluée tant à l'âge préscolaire qu'à l'âge scolaire. Les anomalies neurologiques, même mineures, servent de fil conducteur pour affirmer la nature organique de certains troubles de l'apprentissage. Cet instrument de dépistage permet la mise en place anticipée de stratégies d'intervention. Il se montre également de plus en plus utile dans l'évaluation des pratiques périnatales.

In community after community, pro bono and student-run health clinics have sprung up over the past 30 years, providing critically needed care to medically underserved populations. "Free Clinics" is a mosaic formed by accounts of such clinics around the United States. These wide-ranging narratives � from urban to rural, from primary care to behavioral health care � provide examples that will assist other communities seeking to find the model that best fits their needs. The Patient Protection and Affordable Care Act has improved access to health care for many Americans, but millions remain and will remain uninsured or underinsured. Free clinics provide non-emergency care to those in need. Nationwide, professionals can be found offering volunteer services at these clinics. Contributors to this volume � typically people with personal familiarity (as clinicians or area residents) with the clinics they write about � cover a variety of topics, including a review of the literature, data-driven accounts of clinic usage, and ethical guidelines for student-run clinics. They describe the motivations of clinic staff, the day-to-day work of a family nurse practitioner working in clinics and teaching at a university, the challenges and rewards of providing health care for homeless people, and more. Student-run clinics are the topic of the second section: in addition to providing care to a small subset of those in need, student-run clinics are an important venue for training future clinicians and helping the seeds of altruism with which many enter their professions to germinate. "Free Clinics" will be useful to policymakers, students and faculty in public health and health policy programs, and clinicians and students who are embarking on launching new clinics.

Still the leading cause of death worldwide, heart disease challenges researchers, clinicians, and patients alike. Each day, thousands of patients and their doctors make decisions about coronary angioplasty and bypass surgery. In "Broken Hearts" David S. Jones sheds light on the nature and quality of those decisions. He describes the debates over what causes heart attacks and the efforts to understand such unforeseen complications of cardiac surgery as depression, mental fog, and stroke. Why do doctors and patients overestimate the effectiveness and underestimate the dangers of medical interventions, especially when doing so may lead to the overuse of medical therapies? To answer this question, Jones explores the history of cardiology and cardiac surgery in the United States and probes the ambiguities and inconsistencies in medical decision making. Based on extensive reviews of medical literature and archives, this historical perspective on medical decision making and risk highlights personal, professional, and community outcomes.

The Flesh and Bones of Medical Microbiology presents a very clinically orientated account of the subject. It covers all the key concepts you need with no gaps. It can be used either as an introduction to a topic, or as a revision aid. Dfficult concepts ar

The importance of nutrition in the prevention and treatment of disease and the maintenance of good health is being increasingly recognised. Nutrition is an area that all health professionals need to be aware of and yet one in which few are specifically tr

The surgeon Thomas Pettigrew (1791–1865) was interested in all aspects of antiquity, and gained fame in London society through his mummy-unwrapping parties. (His History of Egyptian Mummies is also reissued in the Cambridge Library Collection.) His interest in the early history of medicine is evidenced by this work, published in 1844, which describes the various forms of superstition which the science of medicine had always attracted since ancient times. Pettigrew considers alchemy and astrology, and the use of talismans, amulets and charms, as well as the history of Egyptian, Greek and Roman medicine, and some modern developments, including 'sympathetical cures' and the rejoining of severed fingers and ears. A chapter is devoted to the belief in the efficacy of the 'royal touch' against the King's Evil (scrofula), and another to the seventeenth-century faith healer Valentine Greatrakes, of whose alleged cures Pettigrew takes a robustly sceptical view.

The physician and botanist William Woodville (1752–1805), a proponent of inoculation against smallpox, was in 1791 appointed physician to the London Smallpox and Inoculation Hospital. Five years later, Edward Jenner announced his experiments with vaccination - inoculation with the much milder cowpox, which conveyed immunity to smallpox without the attendant risk of catching the often fatal disease. Woodville eagerly pursued trials using vaccination, and published the results in this 1799 work, which describes two hundred cases where patients (usually children) were vaccinated with matter obtained from either cows or other cowpox sufferers, and supplies a table of the patterns of infection from person to person. Most of these patients were later tested by inoculation with smallpox, and none caught the disease. This demonstration of the safety and efficacy of vaccination led to its much wider adoption, to which Woodville gave practical support in both England and France.

Despite advances in the diagnosis and treatment of osteoporosis in the last ten years, the condition still poses major clinical challenges. Non-adherence to drug therapy is a widespread problem in patients with rheumatic diseases and osteoporosis in particular.
Part of the Oxford Rheumatology Library, this second edition summarizes the latest developments in the management of osteoporosis and includes new chapters covering the clinical role of denosumab and orthopaedic issues in the management of fractures in patients with osteoporosis. This practical pocketbook is an essential resource for trainees and clinicians in rheumatology, endocrinology, and geriatric medicine, as well as general practitioners and paramedical staff involved in osteoporosis care.