Hepatology at a Glance is an accessible, illustrated introduction to this increasingly important specialty. This brand new title helps the reader to develop a solid understanding of liver disease, and to recognise, diagnose and treat all types of routinely encountered liver and biliary disorders. It covers key areas such as the development, structure and function of the liver, transplantation, surgery and nutrition. Common cases of liver disorders and scenario, and the management of rarer diseases and disorders in special patient groups such as the pregnant are included.

Hepatology at a Glance:
Is a unique and concise resource on hepatology created for junior medical staff
Maintains a practical emphasis, with advice on history, examination and clinical testing
Includes clinical scenarios, with self–assessment questions and full explanations to answers
Follows the curriculum set by and with the support of the British Society of Gastroenterology
Includes a companion website at www.ataglanceseries.com/hepatology featuring 30 MCQs

Providing guidance on all vital aspects of the specialty, Hepatology at a Glance is a succinct and accessible summative resource to enable a thorough understanding of the field.

Stay up to date on today's most common GI and liver disorders and their management with GI/Liver Secrets Plus. This enhanced medical reference book is an excellent resource for understanding the physiology and therapy in hepatic and digestive disease. Whether preparing for an exam or quickly checking a clinical question, the user-friendly Secrets Series® style makes this book a valuable addition to your library!

Well-organized and vibrantly illustrated throughout, Handbook of Liver Disease is a comprehensive yet concise handbook providing authoritative guidance on key clinical issues in liver disease. The quick-reference outline format ensures that you’ll find answers when you need them, and cover-to-cover updates keep you abreast of the recent rapid changes in the field. Written by leading international experts in hepatology, this reference is ideal for hepatologists, gastroenterologists, internists, family practitioners, trainees, and others who diagnose and manage patients with liver disorders.

Firstly, the spectrum of diseases are different. Diseases of infection are still quite prevalent in many parts of the developing world. Moreover, a number of diseases occur in developing countries which are only rarely, if ever, seen in the Western world. One can cite the examples of tropical calcific pancreatitis and veno-occlusive disease of liver, among others.

Secondly, the paucity of diagnostic and therapeutic modalities makes the clinical approach to a patient somewhat different in developing countries. Thirdly, access to Western textbooks is limited in many areas of the developing world. The contributors have kept these things in mind while preparing their part of the book. 

Key Features

• Epidemiology, etiology, clinical features, diagnosis, treatment, and prognosis of hepatobiliary and GI diseases discussed at length

• Emphasis on basic aspects of liver and GI diseases as well as on evidenced-based clinical practice in hepatology and gastroenterology

• Preventive aspects in liver, biliary, and GI diseases duly highlighted

• Well-balanced text: neither too briefed nor too elaborated

• Expected to benefit specialists, postgraduate students, and residents alike

• Contributors from East and West ensure balanced focus on both Eastern and Western disease patterns

• Suitable for ready referencing. 

Table of Contents:

Chapter 1: Gastroesophageal Reflux Disease 1

Chapter 2: Carcinoma of Esophagus 17

Chapter 3: Peptic Ulcer Disease 25

Chapter 4: Peptic Ulcer Disease in Asia–Pacific 31

Chapter 5: Functional Dyspepsia 35

Chapter 6: Gastric Cancer 43

Chapter 7: Malabsorption Disorders 61

Chapter 8: Abdominal Tuberculosis 68

Chapter 9: Inflammatory Bowel Disease 77

Chapter 10: Irritable Bowel Syndrome 94

Chapter 11: Colorectal Carcinoma 101

Chapter 12: Gastrointestinal Lymphomas 121

Chapter 13: Gastrointestinal Stromal Tumor 132

Chapter 14: Acute Diarrheal Diseases 138

Chapter 15: Liver Immunology 145

Chapter 16: Inborn Errors of Bilirubin Metabolism 153

Chapter 17: Hepatitis A and E Viruses 157

Chapter 18: Hepatitis B Virus 164

Chapter 19: Viral Factors and Host Immune Response to Hepatitis B Virus 176

Chapter 20: Hepatitis C 184

Chapter 21: Emerging and Re-Emerging Factors about Hepatitis Virus

Chapter 22: Nonalcoholic Fatty Liver Disease 204

Chapter 23: Alcoholic Liver Disease 214

Chapter 24: Primary Sclerosing Cholangitis 220

Chapter 25: Primary Biliary Cirrhosis 229xxv

Chapter 26: Autoimmune Hepatitis 239

Chapter 27: Amebic Liver Abscess 248

Chapter 28: Pyogenic Liver Abscess 251

Chapter 29: Hydatid Cyst of Liver 257

Chapter 30: Leptospirosis 262

Chapter 31: Cirrhosis of Liver 267

Chapter 32: Ascites 280

Chapter 33: Hepatic Encephalopathy 297

Chapter 34: Hepatocellular Carcinoma 302

Chapter 35: Portal Hypertension: Pathophysiology and Management 313

Chapter 36: Hepatorenal Syndrome 330

Chapter 37: Drug-induced Liver Injury 335

Chapter 38: Acute Liver Failure 346

Chapter 39: Biliary Atresia 359

Chapter 40: Liver Diseases in Pregnancy 369

Chapter 41: Liver Transplantation 379

Chapter 42: Gallstone Disease 404

Chapter 43: Cholangiocarcinoma 412

Chapter 44: Acute Pancreatitis 426

Chapter 45: Chronic Pancreatitis 442

Chapter 46: Carcinoma Pancreas 466

Index 473

This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic and therapeutic procedures and future perspectives.

Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.

 This book discusses the diagnosis, treatment and management of liver disease. Chapter One reviews hepatic hydatidosis. Chapter Two explores the diagnosis, natural history, and management for patients with chronic hepatitis C (CHC). Chapter Three discusses scientific evidence that explains the relationship between metabolic syndrome, non- alcoholic fatty liver disease (NAFLD) and psoriasis and the treatment strategy for this co-morbid condition. Chapter Four examines the pathophysiology and treatment of liver cirrhosis. Chapter Five reviews surgical strategies to push up resection limits in liver disease and liver failure after surgery.

 About this Textbook

The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation.

 This is an invaluable book  for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.

Table of contents

·  1. Anatomy and Embryology of the Liver

·  2. Liver Histology

·  3. Hepatic Progenitor Cells and Biliary Tree Stem Cells

·  4. Hepatocellular Death: Apoptosis, Autophagy, Necrosis and Necroptosis

·  5. Liver Inflammation: Short Uptodate

·  6. Molecular Basis of Fibrogenesis and Angiogenesis During Chronic Liver Disease: Impact of TGF-β and VEGF on Pathogenic Pathways

·  7. Hepatotoxicity: Mechanisms of Liver Injury

·  8. Crosstalk of Molecular Signaling in Hepatocellular Carcinoma

·  9. Drug Induced Liver Injury: Mechanisms, Diagnosis, and Clinical Management

·  10. Acquired Metabolic Disorders

·  11. Vascular Disorders of the Liver

·  12. Liver Ischaemia-Reperfusion Injury

·  13. Autoimmune Hepatitis

·  14. Primary Sclerosing Cholangitis

·  15. Parasitic Liver Diseases

·  16. Viral Hepatitis B

·  17. Viral Hepatitis C

·  18. Non-B, Non-C Viral Hepatitis

·  19. The Microbiome in Liver Diseases

·  20. Polycystic Liver Diseases

·  21. Hepato- and Porto-pulmonary Hypertension

·  22. Hepatic Abscesses

·  23. Liver Cirrhosis

·  24. Primary Biliary Cholangitis

·  25. The Paucity of Interlobular Bile Ducts

·  26. Nonalcoholic Fatty Liver Disease: A Wide Spectrum Disease

·  27. Alcoholic Liver Disease

·  28. Liver Disease in Pregnancy

·  29. Cirrhotic Cardiomyopathy

·  30. Benign Liver Tumours

·  31. Liver Cancer

·  32. Acute Liver Failure

·  33. Chronic Liver Failure and Acute-on-Chronic Liver Failure

·  Part II. Diagnostic Methods

·  34. History and Physical Examination

·  35. Assessment of Liver Function

·  36. Noninvasive Biomarkers for Liver Fibrosis

·  37. Peritoneal Fluid Analysis

·  38. Measurement of the Hepatic Venous Pressure Gradient (HVPG)

·  39. Liver Biopsy for Histopathology

·  40. Liver Ultrasonography

·  41. Endoscopy in Hepatic Diseases

·  42. Dynamic and Multi-phase Contrast-Enhanced CT Scan

·  43. Patient-Specific 3D Printing in Liver Disease

·  44. Dynamic Contrast-Enhanced Ultrasonography of the Liver

·  45. Ultrasound Elastography

·  46. MR Elastography and Functional MRI of the Liver

·  47. Contrast Enhanced MR imaging of Liver

·  48. Transient Elastography in Chronic Liver Diseases

·  49. Portal Venography

·  50. Minilaparoscopy and Conventional Laparoscopy

·  Part III. Treatment

·  51. Medical Nutrition Therapy in Liver Disease

·  52. Molecular Targets in Liver Disease

·  53. Specific Medications for Chronic Viral Hepatitis

·  54. Portal Vein Embolization (PVE) and Partial TIPE ALPPS: Beyond the Limitations of PVE

·  55. Endoscopic and Pharmacological Treatment of Esophageal Varices

·  56. Procedure for Gastric Variceal Bleeding: From BRTO to PARTO to CARTO, Three Decades of Progress

·  57. Endoscopy and Endoscopic Ultrasound for the Evaluation and Treatment of Gastric and Ectopic Varices

·  58. Portacaval Shunting for Portal Hypertension

·  59. Systemic Therapy of Advanced Liver Cancer

·  60. Embolization Therapy for Liver Cancer

·  61. Ablation of Hepatocellular Carcinoma

·  62. Laparoscopic Liver Resection

·  63. New Loco Regional Approaches to Treat Liver Cancer

·  64. Hepatic Encephalopathy

·  65. Management of Ascites

·  66. Extracorporeal Non cellular Liver Assisted Devices

·  67. Extracorporeal Cellular Liver Assisted Devices

·  68. Liver Transplantation for Acute and Chronic Liver Failure

·  69. Surgical Complications Following Liver Transplant and Their Management

·  70. Anaesthesia for Liver Transplantation

·  71. Surgery in Liver Disease

·  72. Robotic Liver Resection

·  73. Cardiac Surgery Risks in Liver Dysfunction

·  74. Future Approaches in Liver Disorders: Regenerative Medicine

• Provides data on correlations of organs with the liver from basic and clinical viewpoints
• Includes chapters on dysbiosis and nonalcoholic steatohepatitis
• Will enrich researchers’, clinical residents’ and medical students’ understanding of the liver

About this book

Based on the results of studies on autoimmunity, the endocrine system, nutrients, metal metabolism and intestinal bacterial flora, this volume thoroughly covers studies on functional correlation of the liver with the spleen, visceral fat, intestinal tract, and central nervous system. Including associations with dysbiosis, nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma, it offers comprehensive data on correlations of organs with the liver from basic and clinical viewpoints. 

The Liver in Systemic Diseases will especially be of interest to researchers, clinical residents and medical students with an interest in hepatology and gastroenterology. Furthermore, the book has interdisciplinary appeal and provides a foundation that will help physicians to consider clinical conditions of diseases from a broader perspective.

About the authors

Hiromasa Ohira, Department of Gastroenterology and Rheumatogy, Fukushima Medical University School of Medicine

Table of contents (16 chapters)

·         Innate Immunity and the Liver

Miura, Kouichi (et al.)

Pages 3-24

·         Microbiota and Liver

Abe, Kazumichi (et al.)

Pages 25-34

·         Spleen and Liver

Torimura, Takuji

Pages 35-50

·         The Brain and Liver

Takikawa, Yasuhiro (et al.)

Pages 51-75

·         Glucose Metabolism and Liver

Hashimoto, Shigeatsu

Pages 77-103

·         Lipid Metabolism and the Liver

Enjoji, Munechika (et al.)

Pages 105-122

·         Metal Metabolism and Liver

Hino, Keisuke (et al.)

Pages 123-146

·         Metabolic Syndrome and the Liver

Yoshiji, Hitoshi

Pages 149-177

·         Heart Disease and the Liver: Interactions Between the Heart and the Liver

Yoshihisa, Akiomi (et al.)

Pages 179-202

Liver and Lung Diseases: Hepatopulmonary Syndrome and Portopulmonary Hypertension

Munakata, Mitsuru

Pages 203-220

·         Physiological and Pathological Interactions Between Liver and Kidney

Watanabe, Tsuyoshi

Pages 221-249

·         Endocrine Disease and Liver

Seike, Masataka

Pages 251-270

·         Rheumatic Diseases and the Liver

Takahashi, Atsushi (et al.)

Pages 271-291

·         Hematologic Diseases and Liver

Nakamura, Nobuhiko (et al.)

Pages 293-306

·         IgG4-Related Diseases and the Liver

Harada, Kenichi

Pages 307-326

·         Infectious Diseases (Non-hepatitis Virus Infection) and the Liver

Yotsuyanagi, Hiroshi

Pages 327-337

This book covers the huge advances made in clinical diagnosisenabling earlier detection, while addressing the recent progressmade in treatment of hepatocellular carcinoma (HCC) to enablesuccessful therapy. It draws on the expertise of an internationally recognizedauthor famed for his understanding, knowledge and efforts indefining terms and diagnosis in this area. The text reviews the full range of pathological information ofHCC based on the study of surgical cases and biopsy materials,along with images, to help compare findings that may be encounteredby pathologists. It also makes special reference to developments inearly stage HCC detection and premalignant lesions which canincrease effective treatment.

Description:

This atlas is a problem-based practical book presenting clinical scenarios for children with liver disease. Each chapter demonstrates the clinical presentation, diagnostic pathway, therapy and outcome. Rich in illustrations of clinical pictures, tables and graphs of data, each chapter also contains pictures of radiology, histopathology and other important diagnostic information. This book outlines a multidisciplinary approach to diagnosis and management of pediatric liver disease and covers diseases encountered in South Asia, the Far East and the Middle East. This work will appeal to a wide readership, from trainees in hepatology  and Paediatric Gastroenterology to General Paediatricians and Allied Health Professionals including Dieticians, Nurses, Transplant Co-Ordinators.

Tabel of contents:

·  1. The Jaundiced Baby

·  2. The Acutely Ill Baby

·  3. The Child with Splenomegaly

·  4. The Child with Abdominal Distention

·  5. The Acutely Ill Child

·  6. Jaundice in an Older Child

·  7. The Child with Chronic Liver Disease

·  8. The Child with Cystic Fibrosis Liver Disease

·  9. Children with Cancer Who Have Liver Disease

·  10. Liver Trauma

·  11. The Child Who Needs a Liver Transplant

·  12. Intestinal Transplantation

·  13. Diseases with Liver and Kidney Involvement

Get the authoritative, up-to-date information you need on liver disease from the 7th Edition of the most trusted reference worldwide. Covering both basic science and recent clinical developments, this revised edition by Drs. Arun J. Sanyal, Thomas D. Boyer, Norah A. Terrault, and Keith D. Lindor, provides an in-depth, comprehensive look at the pathophysiology, diagnostic, and treatment information related to the liver. More than 1,100 figures and tables, many new and in full color, highlight completely updated content throughout.

 Chronic liver disease is one of the most prevalent diseases in the developed world. The large amount of new knowledge has resulted in subspecialities, even in issues such as hepatology. Thus every day, it is more difficult to access all relevant information that is being published. Additionally, biomolecular techniques lead to a level of complexity that is only beneficial when dealt with by professionals. This book attempts to give a broad overview of the molecular biology of the liver, emphasizing how this knowledge is the basis of further treatment. Thus, pathophysiology and therapies are updated in viral hepatitis, hepatic encephalopathy and portal hypertension, among others. However, appended issues that apparently are less relevant such as the stem cell and endocannabinoids are included. These two issues will soon be of importance due to their close relationship with the liver tissue and especially with liver disease. There are also new paradigms such as cell death and the implication of the extracellular matrix, which are also addressed. In addition, important issues such as the stellate cells and their intimate relationship with fibrogenesis are treated in-depth. Also the fundamental role of endothelin in chronic liver disease is examined. Because of its prevalence, NASH was discussed with special interest, with a focus on the process from fatty liver to molecular biology of liver cells and metabolism in chronic liver disease. The authors believe that this is a broad vision that describes the basic pathophysiological mechanisms shared by many liver diseases, giving rational support for specific therapies.

 This new edition is a comprehensive guide to the complete field of liver transplantation for practising transplant surgeons. Presented in a step by step format, the book begins with an overview and discussion on different types of liver disease. Pre- and post-transplant considerations and both deceased and live donor evaluation are examined in depth. The following sections describe operative technique, complications, pathology, radiology and much more. Topics have been fully revised to provide the most up to date information, and the atlas is highly illustrated with surgical images and figures. The book is authored by internationally recognised experts in the field of transplant surgery, led by Ernesto Molmenti from North Shore-LIJ Health System and School of Medicine, New York. Previous edition published in 2002. Key Points * Second edition of comprehensive guide to liver transplantation * Fully revised to provide the most up-to-date information * Authored by internationally recognised experts led by Ernesto Molmenti * Previous edition (9780721695518) published in 2002