Hepatology at a Glance is an accessible, illustrated introduction to this increasingly important specialty. This brand new title helps the reader to develop a solid understanding of liver disease, and to recognise, diagnose and treat all types of routinely encountered liver and biliary disorders. It covers key areas such as the development, structure and function of the liver, transplantation, surgery and nutrition. Common cases of liver disorders and scenario, and the management of rarer diseases and disorders in special patient groups such as the pregnant are included.
Hepatology at a Glance:
Is a unique and concise resource on hepatology created for junior medical staff
Maintains a practical emphasis, with advice on history, examination and clinical testing
Includes clinical scenarios, with selfassessment questions and full explanations to answers
Follows the curriculum set by and with the support of the British Society of Gastroenterology
Includes a companion website at www.ataglanceseries.com/hepatology featuring 30 MCQs
Providing guidance on all vital aspects of the specialty, Hepatology at a Glance is a succinct and accessible summative resource to enable a thorough understanding of the field.
Stay up to date on today's most common GI and liver disorders and their management with GI/Liver Secrets Plus. This enhanced medical reference book is an excellent resource for understanding the physiology and therapy in hepatic and digestive disease. Whether preparing for an exam or quickly checking a clinical question, the user-friendly Secrets Series®style makes this book a valuable addition to your library!
Well-organized and vibrantly illustrated throughout, Handbook of Liver Disease is a comprehensive yet concise handbook providing authoritative guidance on key clinical issues in liver disease. The quick-reference outline format ensures that youll find answers when you need them, and cover-to-cover updates keep you abreast of the recent rapid changes in the field. Written by leading international experts in hepatology, this reference is ideal for hepatologists, gastroenterologists, internists, family practitioners, trainees, and others who diagnose and manage patients with liver disorders.
New to this edition
Features expanded hepatitis chapters, including completely updated coverage of new, safe, and effective oral regimens for the treatment of hepatitis C.
Get a quick, expert overview of hematologic and non-hematologic malignancies for which hematopoietic cell transplantation is a treatment option. Drs. Qaiser Bashir and Mehdi Hamadani provide easy-to-find information on basic science of hematopoietic cell transplantation, pharmacology, workflows and procedures, possible complications and side effects, in addition to the role of HCT in conjunction with clinical cellular therapy.
Discusses high-dose chemotherapeutic regimens and radiation therapy, patient and donor selection and workup, as well as other key aspects of hematopoietic cell transplantation.
Includes practical information on complications, infectious disease, and special populations such as patients with HIV infection.
Consolidates today’s available information in this fast-changing area into one convenient resource.
Table Of Contents:
Bashir: Hematopoietic Cell Transplantation for Malignant Conditions
Section 1: History and Basic Science of Hematopoietic Cell Transplantation
1. History and Current Status of Hematopoietic Cell Transplantation
2. Hematopoietic Cell Transplantation Immunology: Overview and Histocompatibility
This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease, placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation.
The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation.
This is an invaluable book for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.
Table of contents
·1. Anatomy and Embryology of the Liver
·2. Liver Histology
·3. Hepatic Progenitor Cells and Biliary Tree Stem Cells
·4. Hepatocellular Death: Apoptosis, Autophagy, Necrosis and Necroptosis
·5. Liver Inflammation: Short Uptodate
·6. Molecular Basis of Fibrogenesis and Angiogenesis During Chronic Liver Disease: Impact of TGF-β and VEGF on Pathogenic Pathways
·7. Hepatotoxicity: Mechanisms of Liver Injury
·8. Crosstalk of Molecular Signaling in Hepatocellular Carcinoma
·9. Drug Induced Liver Injury: Mechanisms, Diagnosis, and Clinical Management
·10. Acquired Metabolic Disorders
·11. Vascular Disorders of the Liver
·12. Liver Ischaemia-Reperfusion Injury
·13. Autoimmune Hepatitis
·14. Primary Sclerosing Cholangitis
·15. Parasitic Liver Diseases
·16. Viral Hepatitis B
·17. Viral Hepatitis C
·18. Non-B, Non-C Viral Hepatitis
·19. The Microbiome in Liver Diseases
·20. Polycystic Liver Diseases
·21. Hepato- and Porto-pulmonary Hypertension
·22. Hepatic Abscesses
·23. Liver Cirrhosis
·24. Primary Biliary Cholangitis
·25. The Paucity of Interlobular Bile Ducts
·26. Nonalcoholic Fatty Liver Disease: A Wide Spectrum Disease
·27. Alcoholic Liver Disease
·28. Liver Disease in Pregnancy
·29. Cirrhotic Cardiomyopathy
·30. Benign Liver Tumours
·31. Liver Cancer
·32. Acute Liver Failure
·33. Chronic Liver Failure and Acute-on-Chronic Liver Failure
·Part II. Diagnostic Methods
·34. History and Physical Examination
·35. Assessment of Liver Function
·36. Noninvasive Biomarkers for Liver Fibrosis
·37. Peritoneal Fluid Analysis
·38. Measurement of the Hepatic Venous Pressure Gradient (HVPG)
·39. Liver Biopsy for Histopathology
·40. Liver Ultrasonography
·41. Endoscopy in Hepatic Diseases
·42. Dynamic and Multi-phase Contrast-Enhanced CT Scan
·43. Patient-Specific 3D Printing in Liver Disease
·44. Dynamic Contrast-Enhanced Ultrasonography of the Liver
·45. Ultrasound Elastography
·46. MR Elastography and Functional MRI of the Liver
·47. Contrast Enhanced MR imaging of Liver
·48. Transient Elastography in Chronic Liver Diseases
·49. Portal Venography
·50. Minilaparoscopy and Conventional Laparoscopy
·Part III. Treatment
·51. Medical Nutrition Therapy in Liver Disease
·52. Molecular Targets in Liver Disease
·53. Specific Medications for Chronic Viral Hepatitis
·54. Portal Vein Embolization (PVE) and Partial TIPE ALPPS: Beyond the Limitations of PVE
·55. Endoscopic and Pharmacological Treatment of Esophageal Varices
·56. Procedure for Gastric Variceal Bleeding: From BRTO to PARTO to CARTO, Three Decades of Progress
·57. Endoscopy and Endoscopic Ultrasound for the Evaluation and Treatment of Gastric and Ectopic Varices
·58. Portacaval Shunting for Portal Hypertension
·59. Systemic Therapy of Advanced Liver Cancer
·60. Embolization Therapy for Liver Cancer
·61. Ablation of Hepatocellular Carcinoma
·62. Laparoscopic Liver Resection
·63. New Loco Regional Approaches to Treat Liver Cancer
·64. Hepatic Encephalopathy
·65. Management of Ascites
·66. Extracorporeal Non cellular Liver Assisted Devices
This book discusses the diagnosis, treatment and management of liver disease. Chapter One reviews hepatic hydatidosis. Chapter Two explores the diagnosis, natural history, and management for patients with chronic hepatitis C (CHC). Chapter Three discusses scientific evidence that explains the relationship between metabolic syndrome, non- alcoholic fatty liver disease (NAFLD) and psoriasis and the treatment strategy for this co-morbid condition. Chapter Four examines the pathophysiology and treatment of liver cirrhosis. Chapter Five reviews surgical strategies to push up resection limits in liver disease and liver failure after surgery.
This book covers the huge advances made in clinical diagnosisenabling earlier detection, while addressing the recent progressmade in treatment of hepatocellular carcinoma (HCC) to enablesuccessful therapy.
It draws on the expertise of an internationally recognizedauthor famed for his understanding, knowledge and efforts indefining terms and diagnosis in this area.
The text reviews the full range of pathological information ofHCC based on the study of surgical cases and biopsy materials,along with images, to help compare findings that may be encounteredby pathologists. It also makes special reference to developments inearly stage HCC detection and premalignant lesions which canincrease effective treatment.
Firstly, the spectrum of diseases are different. Diseases of infection are still quite prevalent in many parts of the developing world. Moreover, a number of diseases occur in developing countries which are only rarely, if ever, seen in the Western world. One can cite the examples of tropical calcific pancreatitis and veno-occlusive disease of liver, among others.
Secondly, the paucity of diagnostic and therapeutic modalities makes the clinical approach to a patient somewhat different in developing countries. Thirdly, access to Western textbooks is limited in many areas of the developing world. The contributors have kept these things in mind while preparing their part of the book.
• Epidemiology, etiology, clinical features, diagnosis, treatment, and prognosis of hepatobiliary and GI diseases discussed at length
• Emphasis on basic aspects of liver and GI diseases as well as on evidenced-based clinical practice in hepatology and gastroenterology
• Preventive aspects in liver, biliary, and GI diseases duly highlighted
• Well-balanced text: neither too briefed nor too elaborated
• Expected to benefit specialists, postgraduate students, and residents alike
• Contributors from East and West ensure balanced focus on both Eastern and Western disease patterns
• Suitable for ready referencing.
Table of Contents:
Chapter 1: Gastroesophageal Reflux Disease 1
Chapter 2: Carcinoma of Esophagus 17
Chapter 3: Peptic Ulcer Disease 25
Chapter 4: Peptic Ulcer Disease in Asia–Pacific 31
Chapter 5: Functional Dyspepsia 35
Chapter 6: Gastric Cancer 43
Chapter 7: Malabsorption Disorders 61
Chapter 8: Abdominal Tuberculosis 68
Chapter 9: Inflammatory Bowel Disease 77
Chapter 10: Irritable Bowel Syndrome 94
Chapter 11: Colorectal Carcinoma 101
Chapter 12: Gastrointestinal Lymphomas 121
Chapter 13: Gastrointestinal Stromal Tumor 132
Chapter 14: Acute Diarrheal Diseases 138
Chapter 15: Liver Immunology 145
Chapter 16: Inborn Errors of Bilirubin Metabolism 153
Chapter 17: Hepatitis A and E Viruses 157
Chapter 18: Hepatitis B Virus 164
Chapter 19: Viral Factors and Host Immune Response to Hepatitis B Virus 176
Chapter 20: Hepatitis C 184
Chapter 21: Emerging and Re-Emerging Factors about Hepatitis Virus
Chapter 22: Nonalcoholic Fatty Liver Disease 204
Chapter 23: Alcoholic Liver Disease 214
Chapter 24: Primary Sclerosing Cholangitis 220
Chapter 25: Primary Biliary Cirrhosis 229xxv
Chapter 26: Autoimmune Hepatitis 239
Chapter 27: Amebic Liver Abscess 248
Chapter 28: Pyogenic Liver Abscess 251
Chapter 29: Hydatid Cyst of Liver 257
Chapter 30: Leptospirosis 262
Chapter 31: Cirrhosis of Liver 267
Chapter 32: Ascites 280
Chapter 33: Hepatic Encephalopathy 297
Chapter 34: Hepatocellular Carcinoma 302
Chapter 35: Portal Hypertension: Pathophysiology and Management 313
This atlas is a problem-based practical book presenting clinical scenarios for children with liver disease. Each chapter demonstrates the clinical presentation, diagnostic pathway, therapy and outcome. Rich in illustrations of clinical pictures, tables and graphs of data, each chapter also contains pictures of radiology, histopathology and other important diagnostic information. This book outlines a multidisciplinary approach to diagnosis and management of pediatric liver disease and covers diseases encountered in South Asia, the Far East and the Middle East. This work will appeal to a wide readership, from trainees in hepatology and Paediatric Gastroenterology to General Paediatricians and Allied Health Professionals including Dieticians, Nurses, Transplant Co-Ordinators.
Provides data on correlations of organs with the liver from basic and clinical viewpoints
Includes chapters on dysbiosis and nonalcoholic steatohepatitis
Will enrich researchers, clinical residents and medical students understanding of the liver
About this book
Based on the results of studies on autoimmunity, the endocrine system, nutrients, metal metabolism and intestinal bacterial flora, this volume thoroughly covers studies on functional correlation of the liver with the spleen, visceral fat, intestinal tract, and central nervous system. Including associations with dysbiosis, nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma, it offers comprehensive data on correlations of organs with the liver from basic and clinical viewpoints.
The Liver in Systemic Diseases will especially be of interest to researchers, clinical residents and medical students with an interest in hepatology and gastroenterology. Furthermore, the book has interdisciplinary appeal and provides a foundation that will help physicians to consider clinical conditions of diseases from a broader perspective.
About the authors
Hiromasa Ohira, Department of Gastroenterology and Rheumatogy, Fukushima Medical University School of Medicine
Table of contents (16 chapters)
·Innate Immunity and the Liver
Miura, Kouichi (et al.)
·Microbiota and Liver
Abe, Kazumichi (et al.)
·Spleen and Liver
·The Brain and Liver
Takikawa, Yasuhiro (et al.)
·Glucose Metabolism and Liver
·Lipid Metabolism and the Liver
Enjoji, Munechika (et al.)
·Metal Metabolism and Liver
Hino, Keisuke (et al.)
·Metabolic Syndrome and the Liver
·Heart Disease and the Liver: Interactions Between the Heart and the Liver
Yoshihisa, Akiomi (et al.)
Liver and Lung Diseases: Hepatopulmonary Syndrome and Portopulmonary Hypertension
·Physiological and Pathological Interactions Between Liver and Kidney
·Endocrine Disease and Liver
·Rheumatic Diseases and the Liver
Takahashi, Atsushi (et al.)
·Hematologic Diseases and Liver
Nakamura, Nobuhiko (et al.)
·IgG4-Related Diseases and the Liver
·Infectious Diseases (Non-hepatitis Virus Infection) and the Liver
Get the authoritative, up-to-date information you need on liver disease from the 7th Edition of the most trusted reference worldwide. Covering both basic science and recent clinical developments, this revised edition by Drs. Arun J. Sanyal, Thomas D. Boyer, Norah A. Terrault, and Keith D. Lindor, provides an in-depth, comprehensive look at the pathophysiology, diagnostic, and treatment information related to the liver. More than 1,100 figures and tables, many new and in full color, highlight completely updated content throughout.
New to this edition
Includes new information on the rapid changes in treatment paradigms for acute liver failure, the latest treatments for primary biliary cholangitis, full coverage of the gut microbiome and its role in liver disease, the newest developments in drug-induced liver injury, and changes in hepatitis C virus treatment and hot-button concerns about access to care.
New summary boxes at the end of each chapter and a newly streamlined table of contents make it easier to find and understand the information you’re looking for.
Hundreds of brand-new illustrations clearly present key aspects of liver disease.
Chronic liver disease is one of the most prevalent diseases in the developed world. The large amount of new knowledge has resulted in subspecialities, even in issues such as hepatology. Thus every day, it is more difficult to access all relevant information that is being published. Additionally, biomolecular techniques lead to a level of complexity that is only beneficial when dealt with by professionals. This book attempts to give a broad overview of the molecular biology of the liver, emphasizing how this knowledge is the basis of further treatment. Thus, pathophysiology and therapies are updated in viral hepatitis, hepatic encephalopathy and portal hypertension, among others. However, appended issues that apparently are less relevant such as the stem cell and endocannabinoids are included. These two issues will soon be of importance due to their close relationship with the liver tissue and especially with liver disease. There are also new paradigms such as cell death and the implication of the extracellular matrix, which are also addressed. In addition, important issues such as the stellate cells and their intimate relationship with fibrogenesis are treated in-depth. Also the fundamental role of endothelin in chronic liver disease is examined. Because of its prevalence, NASH was discussed with special interest, with a focus on the process from fatty liver to molecular biology of liver cells and metabolism in chronic liver disease. The authors believe that this is a broad vision that describes the basic pathophysiological mechanisms shared by many liver diseases, giving rational support for specific therapies.