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  • 185.00 lei

    Thieme Test Prep for the USMLE®: Pathology is the choice of medical students...

    ...I am very impressed ...These answers and explanations waste no time getting right to the point and hit the high-yield points a student must know... for the USMLE® Step 1 exam. - Nicholas T. Gamboa, MS-II (Second-year medical student, University of Utah School of Medicine)

    These path questions really tested the concepts succinctly and directly. - Amy Leshner (Fourth-year medical student, Chicago College of Osteopathic Medicine)

    ...The major test-prep resources do not focus on these subjects in detail. A question bank...would be beneficial to those who struggle with these as an additional resource for studying ... - Ethan Young (Fourth-year medical student, University of South Dakota, Sanford School of Medicine)

    Thieme Test Prep for the USMLE®: Pathology provides medical students studying for boards with a thorough review of pathology concepts. Co-authored by a pathologist and family practice physician, this robust test prep tool combines pathology with strong clinical correlations.

    Key Highlights

    • Over 1,100 USMLE®-style multiple choice questions and detailed explanations, classified by organ system and difficulty
    • Questions begin with a clinical vignette and approximately 20% are image-based, mirroring the USMLE®-format

    This essential resource will help you assess your knowledge and fully prepare for board examinations.

  • 195.00 lei

     

    Mastering essential microbiology concepts is easier with this vividly illustrated review resource. Part of the popular Lippincott® Illustrated Reviews series, this proven approach uses clear, concise writing and hundreds of dynamic illustrations to take students inside various microorganisms and ensure success on board exams.

    Straightforward lecture-style outlines streamline the review process, accompanied by hundreds of colorful illustrations that make complex concepts more accessible and bring microorganisms to life in vibrant detail. This edition makes exam preparation more efficient than ever with an emphasis on exam-relevant content, as well as hundreds of board-style review questions that help students confidently prepare for the USMLE.

    Revised coverage familiarizes students with the topics and approaches they’re most likely to encounter on exams and in clinical settings.

    Lecture-style outline format guides students step-by-step through essential concepts.

    More than 400 full-color illustrations clarify complex microorganisms and common processes.

    Chapter overviews highlight the most critical information and make studying more efficient and effective.

    Illustrated case studies challenge students to apply their understanding to commonly encountered clinical scenarios.

    Hundreds of USMLE-style review questions help students assess their understanding and prepare for exams.

    Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities!

    Read directly on your preferred device(s), such as computer, tablet, or smartphone

    Easily convert to audiobook, powering your content with natural language text-to-speech

    Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more

     

  • 195.00 lei

     

    • Offers excellent guidance on reporting of cytologic findings in cervical cytology preparations in accordance with the Bethesda System
    • Covers both classic appearances and interpretative dilemmas
    • Reflects recent advances through the inclusion of updated 2014 Bethesda System terminology, explanatory notes and references; a new chapter and additional images

     

    This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update. The new edition has been expanded and revised to take into account the advances and experience of the past decade. A new chapter has been added, the terminology and text have been updated, and various terminological and morphologic questions have been clarified. In addition, new images are included that reflect the experience gained with liquid-based cytology since the publication of the last edition in 2004.

    Among more than 300 images, some represent classic examples of an entity while others illustrate interpretative dilemmas, borderline cytomorphologic features or mimics of epithelial abnormalities. The Bethesda System for Reporting Cervical Cytology, with its user-friendly format, is a “must have” for pathologists, cytopathologists, pathology residents, cytotechnologists, and clinicians.

     “This is a practical reference for cytopathologists, cytotechnologists, residents, fellows, and clinicians. … It is concise, yet exhaustive, and well organized. Images are plentiful and of excellent quality, and do a good job of illustrating different disease entities. … This is a must for everybody signing out gynecologic cytopathology. It is highly recommended.” (Anamarija M. Perry, Doody’s Book Reviews, February, 2016)

     

    Table of Contents (12 Chapters)

    ·         Specimen Adequacy

    Birdsong, George G. (et al.)

    Seiten 1-28

    ·         Non-Neoplastic Findings

    Kurtycz, Daniel F. I. (et al.)

    Seiten 29-89

    ·         Endometrial Cells: The How and When of Reporting

    Cibas, Edmund S. (et al.)

    Seiten 91-102

    ·         Atypical Squamous Cells

    Abdul-Karim, Fadi W. (et al.)

    Seiten 103-134

    ·         Epithelial Cell Abnormalities: Squamous

    Henry, Michael R. (et al.)

    Seiten 135-192

    ·         Epithelial Abnormalities: Glandular

    Wilbur, David C. (et al.)

    Seiten 193-240

    ·         Other Malignant Neoplasms

    Tabbara, Sana O. (et al.)

    Seiten 241-261

    ·         Anal Cytology

    Darragh, Teresa M. (et al.)

    Seiten 263-285

    ·         Adjunctive Testing

    Stoler, Mark H. (et al.)

    Seiten 287-294

    ·         Computer-Assisted Interpretation of Cervical Cytology

    Wilbur, David C. (et al.)

    Seiten 295-300

    ·         Educational Notes and Comments Appended to Cytology Reports

    Nayar, Ritu (et al.)

    Seiten 301-304

    ·         Risk Assessment Approach to Management

    Wentzensen, Nicolas (et al.)

    Seiten 305-313

  • Essentials of Oral Pathology
    La comanda in aproximativ 4 saptamani
    22000lei 200.00 lei

     

    Fully revised and updated, the hallmark features of this new edition include a large number of clinical and radiographic photographs and several photomicrographs of very important cases. Written in simple and lucid language for easy understanding, each topic is presented in a concise and comprehensive manner that will be helpful for both undergraduate and postgraduate students. The latest classifications of oral diseases, recent grading and staging system of tumors have been added. New chapters on diseases of the temporomandibular joint, syndromes related to oral diseases, and important classifications of oral diseases have enriched the text. Relevant key points and important text boxes have been provided in every chapter wherever required for last minute revision. Diagrams, tables and flowcharts have been provided to help students understand the subject better.

  • 26000lei 235.00 lei

    Designed to complement Robbins and Cotran Pathologic Basis of Disease, 9th Edition and Robbins Basic Pathology, 9th Edition, the full-color Robbins and Cotran Atlas of Pathology offers more than 1,500 outstanding illustrations that vividly depict the most common diseases covered in pathology courses and USMLE exams. It's a quick visual reference or review for students and professionals alike. Quickly compare gross, microscopic, and radiologic images with examples of normal organs and tissues. Review just the key information you need to know with help from extensive legends that provide convenient summarizations. Understand the correlation between pathology and clinical history, physical exam findings, and clinical laboratory tests. Access the fully searchable text online at Student Consult. Visualize key pathologic findings with crystal clarity through over 400 new or updated images. Study effectively with this unique companion product! All chapters have been reviewed and revised to reflect the new content found in Robbins and Cotran Pathologic Basis of Disease, 9th Edition.

     

  • Color Atlas of Pathophysiology
    La comanda in aproximativ 4 saptamani
    30000lei 250.00 lei

    Understanding pathophysiology is the first step toward  clinical medicine. This book presents the most important mechanisms of how  disease develops in nearly 200 vivid color plates accompanied by clear text. Every double page, with text on the left and pictures on the right, gives a rapid and complete overview of its topic.

    The contents are organized systematically and a color-coded thumb index makes it easy to navigate through the book. Where necessary for clarity, the basics of physiology are explained again.

    Numerous clinical references illustrate the links between theory and practice. The pocket atlas has been fully revised and updated for the third edition. It now includes detailed information about malaria, energy metabolism, eating disorders, and obesity. Color Atlas of Pathophysiology is the ideal supplement to Color Atlas of Physiology!

  • 31000lei 260.00 lei

     

    Description:

    The newest addition to the highly regarded Robbins family of pathology references, Robbins Essential Pathology is a concise resource that covers the core knowledge needed for coursework and exams in an integrated, multimedia format designed for today’s students. Ideal for use with an integrated medical curriculum, this easy-to-study multimedia package provides reliable Robbins content in a concentrated, highly efficient format, now fully integrated with interactive digital resources (cases, MCQs, images). Efficient, effective, and up to date, this new Robbins learning resource delivers the essential information you need to obtain a strong scientific foundation in pathology.

    The most concise Robbins text available, providing high-quality content and a case-based approach in a focused, multimedia learning package for coursework and exam preparation.

    Focuses on the core knowledge of disease mechanisms and essential clinical aspects that medical students need to know.

    Features more than 500 images and tables that illustrate key disorders and concepts.

     

    Table of Contents:

     

    1. Cell Injury and Cell Death

    Overview of Cell Injury

    Reversible Cell Injury

    Cell Death

    Mechanisms of Cell Injury and Death

    Cellular Aging

    Cellular Adaptations to Stress

    Pathologic Accumulations in Cells

    2. Inflammation and Repair

    Overview of Inflammation

    Acute Inflammation

    Chronic Inflammation

    Tissue Repair

    3. Hemodynamic Disorders, Thromboembolism, and Shock

    Hyperemia, Congestion, and Edema

    4. Diseases of the Immune System

    Hypersensitivity Disorders

    Autoimmune Diseases

    Rejection of Transplants

    Immunodeficiency Disorders

    Acquired Immunodeficiency Syndrome

    Amyloidosis

    5. Neoplasia

    Definition of Neoplasia

    Benign and Malignant Neoplasms

    Nomenclature

    Characteristics of Benign and Malignant Neoplasms

    Molecular Basis of Neoplasia

    Hallmarks of Cancer

    Clinical Aspects of Neoplasia

    6. Genetic Diseases

    Mendelian Disorders: Diseases Caused by Single-Gene Defects

    Complex Multigenic Disorders

    Cytogenetic Disorders

    Single-Gene Disorders with Atypical Patterns of Inheritance

    7. Diseases of Blood Vessels

    Mechanisms of Vascular Diseases

    Congenital Vascular Anomalies

    Hypertension

    Atherosclerosis

    Aneurysms and Dissections

    Vasculitis

    Disorders of Veins

    Tumors of Blood Vessels and Lymphatics

    8. Heart

    Congenital Heart Disease

    Ischemic Heart Disease

    Hypertensive Heart Disease

    Valvular Heart Disease

    Cardiomyopathies and Myocarditis

    Congestive Heart Failure

    Cardiac Tumors

    9. Hematopoietic and Lymphoid Systems

    Red Blood Cell Disorders

    White Blood Cell Disorders

    Neoplastic Proliferations of White Cells

    Bleeding Disorders

    Disorders of Spleen and Thymus

    Disorders of the Thymus

    10. Lung and Upper Respiratory Tract

    Acute Respiratory Distress Syndrome

    Obstructive Lung Diseases

    Restrictive Lung Diseases

    Pulmonary Diseases of Vascular Origin

    Pulmonary Infections

    Lung, Pleural, and Upper Airway Tumors

    11. Kidney

    Overview of Renal Diseases

    Diseases of Glomeruli

    Diseases of Tubules and Interstitium

    Diseases of Blood Vessels

    Tumors of the Kidney

    12. Gastrointestinal System

    Congenital Anomalies of the Gastrointestinal Tract

    Disorders of the Esophagus

    13. Liver, Biliary System, and Pancreas

    Disorders of the Liver

    Disorders of the Biliary System

    Disorders of the Pancreas

    14. Male Genital Tract, Prostate, and Bladder

    Penis

    Scrotum, Testis, and Epididymis

    Prostate

    Ureter, Bladder, and Urethra

    Sexually Transmitted Diseases

    15. Female Genital Tract and Breast

    Vulva

    Vagina

    Cervix

    Uterus

    Fallopian Tubes

    Ovaries

    Diseases of Pregnancy

    Breast

    16. Endocrine System

    Overview of the Endocrine System

    Pituitary Gland

    Thyroid

    Parathyroid Glands

    Endocrine Pancreas: Diabetes

    Adrenal Glands

    Multiple Endocrine Neoplasia Syndromes

    17. Disorders of the Nervous System

    Congenital Malformations of the CNS

    Cerebral Edema, Herniation, and Hydrocephalus

    Cerebrovascular Diseases

    CNS Trauma

    CNS Infections

    Demyelinating Diseases

    Neurodegenerative Diseases

    CNS Tumors

    Disorders of Peripheral Nerves

    18. Musculoskeletal System and Skin

    Bones

    Joints

    Skeletal Muscle

    Skin

    19. Environmental Disease

    Metals as Environmental Pollutants

    Tobacco

    Alcohol

    Injury by Therapeutic Drugs and Drugs of Abuse

    Injury Produced by Ionizing Radiation

    Nutritional Diseases

    Index

     

  • 270.00 lei

    Description:

    Generations of medical and other health science students have been helped to pass their exams by the Illustrated books. The visual presentation of the subject matter, divided in to one-page units, makes for easy learning and recall. Now fully revised in this eighth edition, Pathology Illustrated covers all the essential information in as clear and concise a way as possible, focussing on what is most clinically important. Pathology remains central to the study of medicine and forms the bridge between the basic sciences and clinical medicine, making this book an essential purchase for today’s student.

    • Covers both basic and systematic pathology
    • Each topic clearly summarised in one/two pages
    • Visual presentation for easy learning and recall
    • Fully updated throughout - including new and expanded coverage on the essentials of genetic disease, haemodynamics and shock and basic techniques in molecular biology
    • Includes an all new interactive eBook version
    • downloadable for anytime access to the complete content
    • enhanced with new, interactive multiple-choice questions for each chapter, to test your understanding and aid exam preparation

     

     

    ·  Introduction

    ·  Causes Of Disease

    ·  Methods in Pathology

    ·  Chapter 1 Cell and Tissue Damage

    ·  Cellular Physiology and Pathology

    ·  Control of Cell Number

    ·  Cell Injury

    ·  Apoptosis

    ·  Apoptosis

    ·  Necrosis

    ·  Necrosis – Autolysis

    ·  Reversible Cell Damage

    ·  Reversible Cell Damage

    ·  Mechanisms of Cell Damage – Free Radicals

    ·  Atrophy

    ·  Ageing

    ·  Depositions – Amyloid

    ·  Amyloid Classification

    ·  Depositions – Calcification

    ·  Endogenous Pigmentation

    ·  Exogenous Pigmentation

    ·  Chapter 2 Genetic Disease

    ·  Heredity, Genes and Disease

    ·  Deoxyribonucleic Acid (DNA)

    ·  Mitosis and Meiosis

    ·  Genetic Abnormalities and Associated Disorders

    ·  Types of Genetic Abnormalities

    ·  Diagnosis of Genetic Abnormalities

    ·  Gene Therapy

    ·  Drug Design

    ·  Chapter 3 Inflammation, Healing and Repair

    ·  Inflammation

    ·  Acute Inflammation

    ·  Sequels of Acute Inflammation

    ·  Chronic Inflammation

    ·  Ulceration – Benign

    ·  Ulceration – Malignant

    ·  Inflammation – Anatomical Varieties

    ·  Healing

    ·  Wound Healing

    ·  Healing – Fibrosis

    ·  Healing – Special Situations

    ·  Fracture Healing

    ·  Chapter 4 Haemodynamic Disorders, Thrombosis and Shock

    ·  General Considerations

    ·  Factors Leading to Thrombosis

    ·  Common Sites and Types of Thrombus

    ·  Sequels of Thrombosis

    ·  Embolism

    ·  Arterial Obstruction

    ·  Important Sites of Infarction

    ·  Normal Tissue Fluid Circulation

    ·  Oedema

    ·  Shock

    ·  Shock – Individual Organs

    ·  Shock – Individual Organs: Outcome

    ·  Chapter 5 Infection and Immunity

    ·  Infection

    ·  Sepsis

    ·  Bacteraemia

    ·  Pyaemia

    ·  Acute Bacterial Infection

    ·  Chronic Bacterial Infection (Granulomas)

    ·  Virus Infections

    ·  Host/Virus Interaction

    ·  Opportunistic Infections

    ·  Infection – General Effects

    ·  Immunity

    ·  Adaptive Immunity

    ·  The Adaptive Immune Response

    ·  Cellular Basis of the Adaptive Immune Response

    ·  Genetic Influences on the Immune Response

    ·  Cellular Immunity

    ·  Cytokines

    ·  Cytokines Involved In Adaptive Immunity

    ·  Humoral Immunity

    ·  Immunoglobulins

    ·  Immune Reactions

    ·  Tolerance

    ·  Immunopathology

    ·  Hypersensitivity States

    ·  Immune Deficiency States

    ·  Immune Deficiency States – AIDS

    ·  Auto-Immune Diseases

    ·  Applied Immunology

    ·  Applied Immunology – Tissue Transplantation

    ·  Chapter 6 Neoplasia

    ·  Neoplasia

    ·  Non-Neoplastic Proliferation

    ·  Neoplastic Proliferation

    ·  Neoplasms – Classification

    ·  Benign Tumours – Histology

    ·  Malignant Tumours – Histology

    ·  Benign Epithelial Tumours

    ·  Benign Connective Tissue Tumours

    ·  Malignant Epithelial Tumours

    ·  Types of Carcinoma

    ·  Malignant Connective Tissue Tumours

    ·  Sarcomas

    ·  Other Tumour Types

    ·  Spread of Tumours

    ·  Lymphatic Spread

    ·  Blood Spread

    ·  Other Modes of Spread of Tumours

    ·  Effects of Tumours

    ·  Tumour Markers

    ·  Diagnosis of Tumours Immunocytochemistry

    ·  Pre-Malignancy

    ·  Carcinoma in Situ (Intra-Epithelial Neoplasia)

    ·  Carcinogenesis

    ·  Carcinogenesis – Viruses

    ·  Carcinogenesis – Heredity

    ·  Oncogenes and Tumour Suppressor Genes

    ·  Oncogenes

    ·  Tumour Suppressor Genes

    ·  Carcinogenesis – Summary

    ·  Chapter 7 Cardiovascular Diseases

    ·  Cardiac Function

    ·  Heart Failure

    ·  Effects of Heart Failure

    ·  Acute Pulmonary Oedema

    ·  Chronic Pulmonary Oedema

    ·  Congestive Cardiac Failure

    ·  High Output Cardiac Failure

    ·  Diseases of Arteries – Arteriosclerosis

    ·  Atheroma (Atherosclerosis)

    ·  Atheroma – Complications

    ·  Atheroma – Aetiology

    ·  Atheroma – Aetiology and Progression

    ·  Hypertension

    ·  Hypertension – Mechanisms

    ·  Hypertension – Essential and Secondary

    ·  Ischaemic Heart Disease

    ·  Myocardial Infarction

    ·  Chronic Ischaemic Heart Disease

    ·  Ischaemic Heart Disease

    ·  Miscellaneous Affections of the Myocardium

    ·  Valvular Heart Disease

    ·  Mitral Valve Disease

    ·  Aortic Valve Disease

    ·  Endocarditis

    ·  Cardiac Arrhythmias

    ·  Congenital Heart Disease

    ·  Diseases of the Pericardium

    ·  Cardiac Tumours

    ·  Diseases of Blood Vessels

    ·  Aneurysms

    ·  Arterial Diseases – Miscellaneous

    ·  Diseases of Veins

    ·  Varicose Veins

    ·  Diseases of Lymphatics

    ·  Lymphatic Obstruction

    ·  Vascular Tumours

    ·  Chapter 8 Respiratory System

    ·  Upper Respiratory Tract

    ·  Rhinitis

    ·  Acute Pharyngitis, Tracheitis and Laryngitis

    ·  Tumours of the Upper Respiratory Tract

    ·  Lungs – Anatomy

    ·  Respiration

    ·  Acute Bronchitis

    ·  Bronchial Asthma

    ·  Chronic Obstructive Pulmonary Disease (COPD)

    ·  Emphysema

    ·  Bronchiectasis

    ·  Pneumonia – Bronchopneumonia

    ·  Pneumonia - Lobar Pneumonia

    ·  Atypical Pneumonias

    ·  Pneumonia – Special Types

    ·  Lung Abscess

    ·  Tuberculosis (TB)

    ·  Spread of Tuberculosis

    ·  Pneumoconioses (Dust Diseases)

    ·  Asbestosis

    ·  Diffuse Parenchymal Lung Disease

    ·  Lung Cancer

    ·  Other Tumours of the Bronchi and Lungs

    ·  Diseases of the Pleura

    ·  Chapter 9 Gastrointestinal Tract

    ·  The Mouth

    ·  Oral Cancer

    ·  Mouth

    ·  Dental Caries and Periodontal Disease

    ·  Diseases of the Salivary Glands

    ·  Salivary Glands – Benign Tumours

    ·  Salivary Glands – Carcinomas

    ·  Oesophagus

    ·  Oesophagus – Tumours

    ·  Stomach

    ·  Gastritis

    ·  Peptic Ulceration

    ·  Peptic Ulcer – Aetiology

    ·  Gastric Carcinoma

    ·  Small Intestine – Malabsorption

    ·  Malabsorption

    ·  Crohn's Disease

    ·  Ulcerative Colitis

    ·  Crohn's Disease and Ulcerative Colitis

    ·  Microscopic Colitis

    ·  Intestinal Infections

    ·  Typhoid

    ·  Bacillary Dysentery

    ·  Amoebic Dysentery

    ·  Tuberculous Enteritis and Pseudomembranous Colitis

    ·  Appendicitis

    ·  Appendicitis – Sequels

    ·  Diverticular Disease

    ·  Ischaemia and the Intestines

    ·  Intestinal Obstruction

    ·  Hernia

    ·  Hernia – Complications

    ·  Intussusception

    ·  Volvulus and Hirschsprung Disease

    ·  Tumours of the Colon

    ·  Carcinoma of the Colon

    ·  Tumours of Small Intestine

    ·  Carcinoid Tumours

    ·  The Peritoneal Cavity

    ·  Chapter 10 Liver, Gall Bladder and Pancreas

    ·  Liver – Anatomy

    ·  Anatomy – Hepatic Lesions

    ·  Jaundice

    ·  Viral Hepatitis

    ·  Hepatitis B Infection

    ·  Viral Hepatitis

    ·  Chronic Hepatitis

    ·  Alcoholic Liver Disease

    ·  Alcoholic Hepatitis

    ·  Cirrhosis

    ·  Biliary Disease

    ·  Hepatocellular Failure

    ·  Hepatocellular Failure

    ·  Portal Hypertension

    ·  Metabolic Disorders of the Liver

    ·  Infections

    ·  Infections

    ·  Tumours of the Liver

    ·  Primary Carcinoma of Liver

    ·  Primary Liver Cell Tumours

    ·  Gallbladder and Bile Duct – Anatomy

    ·  Gallstones

    ·  Gallstones – Aetiology

    ·  Pancreas

    ·  Acute Pancreatitis

    ·  Chronic Pancreatitis

    ·  Cystic Fibrosis (Mucoviscidosis)

    ·  Tumours of Pancreas

    ·  Chapter 11 Haemopoietic and Lympho-Reticular Tissues

    ·  Haemopoiesis

    ·  Haematology – Laboratory Tests

    ·  Anaemia

    ·  Iron Deficiency Anaemia

    ·  The Megaloblastic Anaemias

    ·  Pernicious Anaemia (PA)

    ·  Folic Acid Deficiency

    ·  The Haemolytic Anaemias

    ·  Extrinsic Haemolytic Anaemias

    ·  Incompatible Blood Transfusion/Haemolytic Disease of the Newborn

    ·  Haemolytic Disease of the Newborn

    ·  Extrinsic Haemolytic Anaemias

    ·  Extrinsic Haemolytic Anaemias – Malaria

    ·  Intrinsic Haemolytic Anaemias

    ·  Disorders of Haemoglobin Synthesis

    ·  The Thalassaemias

    ·  Sickle Cell Disease

    ·  Anaemia of Chronic Disorders

    ·  Aplastic Anaemia

    ·  Polycythaemia

    ·  Neutrophil Granulocytes

    ·  Disorders of Neutrophils – Agranulocytosis

    ·  Disorders of Neutrophils

    ·  Platelets and Coagulation

    ·  Disorders of Platelets

    ·  The Coagulation Cascade

    ·  Inherited Defects of Coagulation

    ·  Acquired Defects of Coagulation

    ·  Disseminated Intravascular Coagulation

    ·  Thrombophilia – Thrombotic Disorders

    ·  The Lymphoid System

    ·  Lymphadenopathy

    ·  Lymphadenopathy – Infections

    ·  Lymphadenopathy

    ·  Lymphadenopathy – Non-Infective Causes

    ·  Spleen

    ·  Splenomegaly

    ·  Diseases of the Spleen – Miscellaneous

    ·  Thymus

    ·  Neoplastic Lymphadenopathy

    ·  Non-Hodgkin Lymphomas

    ·  Plasma Cell Tumours

    ·  Non-Hodgkin Lymphoma – T Cell

    ·  Hodgkin Lymphoma

    ·  Leukaemias

    ·  Acute Myeloblastic Leukaemia (AML)

    ·  Chronic Myeloid Leukaemia (CML)

    ·  Chronic Lymphocytic Leukaemia

    ·  Acute Lymphoblastic Leukaemia (ALL)

    ·  Myeloproliferative Disorders

    ·  Chapter 12 Genitourinary System

    ·  Kidney – Structure and Function

    ·  Glomerular Structure and Function

    ·  Glomerular Diseases

    ·  Glomerulonephritis – Disease Mechanisms

    ·  Acute Diffuse Proliferative (Post-Infectious) Glomerulonephritis

    ·  Crescentic (Rapidly Progressive) Glomerulonephritis

    ·  Membranous Glomerulonephritis

    ·  Mesangiocapillary (Membranoproliferative) Glomerulonephritis

    ·  Focal Glomerulonephritis

    ·  IgA Nephropathy

    ·  Minimal Change Glomerulonephritis

    ·  Chronic Glomerulonephritis (GN)

    ·  Glomerular Disease in Systemic Disorders

    ·  The Kidney and Hypertension

    ·  Chronic Renal Failure

    ·  Infections of the Kidney and Urinary Tract

    ·  Acute Pyelonephritis

    ·  Acute Pyelonephritis

    ·  Chronic Pyelonephritis

    ·  Tuberculosis of the Kidney

    ·  Intercurrent Renal Conditions

    ·  Renal Function and Pregnancy

    ·  Renal Tubule – Structure and Function

    ·  Acute Kidney Injury (AKI) (Acute Tubular Necrosis)

    ·  Acute Kidney Injury (Acute Tubular Necrosis)

    ·  Tubulo-Interstitial Diseases

    ·  Metabolic Tubular Lesions

    ·  Thrombotic Microangiopathies (Haemolytic Uraemic Syndrome)

    ·  Pathological Complications of Renal Replacement Therapies

    ·  Congenital Disorders

    ·  Polycystic Kidney Disease

    ·  Urinary Calculi

    ·  Tumours of the Kidney

    ·  Diseases of the Urinary Tract

    ·  Urinary Tract Infection

    ·  Tumours of the Urothelium

    ·  The Prostate

    ·  Diseases of the Prostate

    ·  Adenocarcinoma of the Prostate

    ·  Diseases of the Penis

    ·  Diseases of the Testis

    ·  Tumours of the Testis

    ·  Infertility

    ·  Chapter 13 Female Genital System and Breast

    ·  Female Genital Tract – Anatomy and Physiology

    ·  Diseases of Vagina and Vulva

    ·  Diseases of the Cervix

    ·  Cervical Intraepithelial Neoplasia (CIN)

    ·  Carcinoma of Cervix

    ·  Cyclical Endometrial Changes

    ·  Diseases of the Endometrium

    ·  Endometrial Hyperplasia

    ·  Endometrial Carcinoma

    ·  Diseases of the Myometrium

    ·  Diseases of the Fallopian Tube

    ·  Diseases of the Ovaries

    ·  Common Epithelial Ovarian Tumours

    ·  Carcinoma of the Ovary

    ·  Tumours of the Ovary – Sex Cord Stromal

    ·  Tumours of the Ovary – Germ Cell

    ·  Tumours of the Ovary – Germ Cell and Secondaries

    ·  Ectopic Pregnancy

    ·  Gestational Trophoblast Disease

    ·  Breast Structure and Function

    ·  Benign Diseases of the Breast

    ·  Benign Breast Tumours and in situ Carcinoma

    ·  Carcinoma of the Breast

    ·  Chapter 14 Nervous System

    ·  Nervous System – Anatomy and Physiology

    ·  Neuronal Damage

    ·  Glial Reactions

    ·  Increased Intracranial Pressure

    ·  Cerebral Oedema

    ·  Increased Intracranial Pressure – Secondary Complications

    ·  Circulatory Disturbances

    ·  Cerebral Infarction

    ·  Brain Damage Due to Cardiac Arrest

    ·  Cerebral Infarction

    ·  Cerebral Haemorrhage

    ·  Subarachnoid Haemorrhage

    ·  Head Injury

    ·  Ageing and Dementia

    ·  Alzheimer's Disease

    ·  Dementia

    ·  Infections

    ·  Bacterial Infections

    ·  Virus Infections

    ·  Prion Diseases

    ·  Miscellaneous Infections and Infestations

    ·  Demyelinating Diseases

    ·  Parkinson's Disease

    ·  Miscellaneous Disorders

    ·  Diseases of the Spinal Cord

    ·  Disorders of Motor Pathways

    ·  Motor Neurone Disease

    ·  Mixed Motor and Sensory Disorders

    ·  Sensory Disorders

    ·  The Peripheral Nerves/the Neuropathies

    ·  The Neuropathies

    ·  Hydrocephalus

    ·  Developmental Abnormalities

    ·  Tumours of the Nervous System

    ·  Secondary Brain Tumours

    ·  Primary Brain Tumours

    ·  Tumours of the Nervous System

    ·  Tumours of Peripheral Nerves

    ·  Cerebrospinal Fluid

    ·  The Eye

    ·  Chapter 15 Musculo-Skeletal System

    ·  Bone

    ·  Bone Turnover

    ·  Metabolic Bone Disease

    ·  Bone – Miscellaneous

    ·  Infections of Bone

    ·  Developmental Abnormalities

    ·  Tumours in Bone

    ·  Joint Disease

    ·  Joint Trauma

    ·  Osteoarthritis (OA)

    ·  Rheumatoid Arthritis (RA)

    ·  Sero-Negative Arthritis

    ·  Infections of Joints

    ·  Joint and Soft Tissues – Miscellaneous

    ·  Para-Articular Tissues – Miscellaneous

    ·  Collagen Diseases

    ·  Skeletal Muscle

    ·  Atrophy and Hypertrophy

    ·  Neurogenic Atrophy

    ·  Myasthenia Gravis

    ·  Muscle Damage

    ·  Muscular Dystrophy

    ·  Inherited Myopathies

    ·  Acquired Myopathies

    ·  Muscle Diseases – Diagnosis

    ·  Chapter 16 Endocrine System

    ·  Endocrine Diseases

    ·  Pituitary Gland

    ·  Pituitary Hyperfunction

    ·  Hypopituitarism

    ·  Thyroid Gland – Underactivity

    ·  Thyroid Gland – Overactivity

    ·  Thyroid Gland

    ·  Tumours of Thyroid

    ·  Adrenal Gland

    ·  Adrenal Cortex – Overactivity

    ·  Adrenal Cortex – Hypofunction

    ·  Adrenal Cortex and Medulla

    ·  Endocrine Pancreas

    ·  Parathyroid Glands

    ·  Multiple Endocrine Neoplasia Syndromes (MENS)

  • 36000lei 320.00 lei

    Description:

    Part of the trusted Robbins and Cotran familyRobbins Basic Pathology provides a readable, well-illustrated and concise overview of the principles of human pathology that's ideal for today's busy students. This thoroughly revised edition continues with a strong emphasis on pathogenesis and the clinical features of disease, adding new artwork and more schematic diagrams to further aid in summarizing key pathologic processes and expand the already impressive illustration program.

    • Excellent art program boasts high-quality photomicrographs, gross photos, and radiologic images to supplement the world-class illustrations.
    • Bulleted summary boxes provide quick access to key information and easy review of key concepts.
    • Highlights pathogenesismorphology, and pathophysiologic content throughout.
    • Includes increased and updated clinical topics.
    • New artwork and more schematic diagrams summarize key pathologic processes.

     

    ·  Chapter 1 The Cell as a Unit of Health and Disease

    ·  The Genome

    ·  Cellular Housekeeping

    ·  Cellular Metabolism and Mitochondrial Function

    ·  Cellular Activation

    ·  Growth Factors and Receptors

    ·  Extracellular Matrix

    ·  Maintaining Cell Populations

    ·  Suggested Readings

    ·  Chapter 2 Cell Injury, Cell Death, and Adaptations

    ·  Introduction to Pathology

    ·  Overview of Cellular Responses to Stress and Noxious Stimuli

    ·  Causes of Cell Injury

    ·  Sequence of Events in Cell Injury and Cell Death

    ·  Autophagy

    ·  Mechanisms of Cell Injury and Cell Death

    ·  Cellular Adaptations to Stress

    ·  Intracellular Accumulations

    ·  Pathologic Calcification

    ·  Cellular Aging

    ·  Suggested Readings

    ·  Chapter 3 Inflammation and Repair

    ·  Overview of Inflammation: Definitions and General Features

    ·  Causes of Inflammation

    ·  Recognition of Microbes and Damaged Cells

    ·  Acute Inflammation

    ·  Mediators of Inflammation

    ·  Morphologic Patterns of Acute Inflammation

    ·  Outcomes of Acute Inflammation

    ·  Chronic Inflammation

    ·  Systemic Effects of Inflammation

    ·  Tissue Repair

    ·  Suggested Readings

    ·  Chapter 4 Hemodynamic Disorders, Thromboembolism, and Shock

    ·  Hyperemia and Congestion

    ·  Edema

    ·  Hemorrhage

    ·  Hemostasis and Thrombosis

    ·  Embolism

    ·  Infarction

    ·  Shock

    ·  Suggested Readings

    ·  Chapter 5 Diseases of the Immune System

    ·  The Normal Immune Response

    ·  Cells and Tissues of the Immune System

    ·  Overview of Lymphocyte Activation and Adaptive Immune Responses

    ·  Hypersensitivity: Immunologically Mediated Tissue Injury

    ·  Autoimmune Diseases

    ·  Rejection of Transplants

    ·  Immunodeficiency Syndromes

    ·  Acquired Immunodeficiency Syndrome

    ·  Amyloidosis

    ·  Suggested Readings

    ·  Chapter 6 Neoplasia

    ·  Nomenclature

    ·  Characteristics of Benign and Malignant Neoplasms

    ·  Epidemiology

    ·  Cancer Genes

    ·  Genetic Lesions in Cancer

    ·  Carcinogenesis: A Multistep Process

    ·  Hallmarks of Cancer

    ·  Etiology of Cancer: Carcinogenic Agents

    ·  Clinical Aspects of Neoplasia

    ·  Suggested Readings

    ·  Chapter 7 Genetic and Pediatric Diseases

    ·  Genetic Diseases

    ·  Pediatric Diseases

    ·  Suggested Readings

    ·  Chapter 8 Environmental and Nutritional Diseases

    ·  Health Effects of Climate Change

    ·  Toxicity of Chemical and Physical Agents

    ·  Environmental Pollution

    ·  Effects of Tobacco

    ·  Effects of Alcohol

    ·  Injury by Therapeutic Drugs and Drugs of Abuse

    ·  Injury by Physical Agents

    ·  Nutritional Diseases

    ·  Suggested Readings

    ·  Chapter 9 General Pathology of Infectious Diseases

    ·  General Principles of Microbial Pathogenesis

    ·  The Microbiome

    ·  Techniques for Identifying Infectious Agents

    ·  Newly Emerging and Reemerging Infectious Diseases

    ·  Agents of Bioterrorism

    ·  Transmission and Dissemination of Microbes

    ·  How Microorganisms Cause Disease

    ·  Immune Evasion by Microbes

    ·  Spectrum of Inflammatory Responses to Infection

    ·  Suggested Readings

    ·  Chapter 10 Blood Vessels

    ·  Structure and Function of Blood Vessels

    ·  Congenital Anomalies

    ·  Blood Pressure Regulation

    ·  Hypertensive Vascular Disease

    ·  Vascular Wall Response to Injury

    ·  Arteriosclerosis

    ·  Atherosclerosis

    ·  Aneurysms and Dissections

    ·  Vasculitis

    ·  Disorders of Blood Vessel Hyperreactivity

    ·  Veins and Lymphatics

    ·  Tumors

    ·  Pathology of Vascular Intervention

    ·  Suggested Readings

    ·  Chapter 11 Heart

    ·  Overview of Heart Disease

    ·  Heart Failure

    ·  Congenital Heart Disease

    ·  Ischemic Heart Disease

    ·  Arrhythmias

    ·  Hypertensive Heart Disease

    ·  Valvular Heart Disease

    ·  Cardiomyopathies and Myocarditis

    ·  Pericardial Disease

    ·  Cardiac Tumors

    ·  Cardiac Transplantation

    ·  Suggested Readings

    ·  Chapter 12 Hematopoietic and Lymphoid Systems

    ·  Red Cell Disorders

    ·  White Cell Disorders

    ·  Bleeding Disorders

    ·  Complications of Transfusion

    ·  Disorders of the Spleen and Thymus

    ·  Suggested Readings

    ·  Chapter 13 Lung

    ·  Atelectasis (Collapse)

    ·  Acute Respiratory Distress Syndrome

    ·  Obstructive Versus Restrictive Pulmonary Diseases

    ·  Obstructive Lung (Airway) Diseases

    ·  Chronic Interstitial (Restrictive, Infiltrative) Lung Diseases

    ·  Pulmonary Diseases of Vascular Origin

    ·  Pulmonary Infections

    ·  Lung Tumors

    ·  Pleural Lesions

    ·  Lesions of the Upper Respiratory Tract

    ·  Suggested Readings

    ·  Chapter 14 Kidney and Its Collecting System

    ·  Clinical Manifestations of Renal Diseases

    ·  Glomerular Diseases

    ·  Diseases Affecting Tubules and Interstitium

    ·  Diseases Involving Blood Vessels

    ·  Chronic Kidney Disease

    ·  Cystic Diseases of the Kidney

    ·  Urinary Outflow Obstruction

    ·  Congenital and Developmental Anomalies

    ·  Neoplasms

    ·  Suggested Readings

    ·  Chapter 15 Oral Cavities and Gastrointestinal Tract

    ·  Oral Cavity

    ·  Esophagus

    ·  Stomach

    ·  Small and Large Intestines

    ·  Appendix

    ·  Suggested Readings

    ·  Chapter 16 Liver and Gallbladder

    ·  The Liver and Bile Ducts

    ·  Gallbladder

    ·  Suggested Readings

    ·  Chapter 17 Pancreas

    ·  Congenital Anomalies

    ·  Pancreatitis

    ·  Pancreatic Neoplasms

    ·  Suggested Readings

    ·  Chapter 18 Male Genital System and Lower Urinary Tract

    ·  Penis

    ·  Scrotum, Testis, and Epididymis

    ·  Prostate

    ·  Ureter, Bladder, and Urethra

    ·  Sexually Transmitted Diseases

    ·  Suggested Readings

    ·  Chapter 19 Female Genital System and Breast

    ·  Vulva

    ·  Vagina

    ·  Cervix

    ·  Uterus

    ·  Fallopian Tubes

    ·  Ovaries

    ·  Diseases of Pregnancy

    ·  Breast

    ·  Suggested Readings

    ·  Chapter 20 Endocrine System

    ·  Pituitary

    ·  Thyroid

    ·  Parathyroid Glands

    ·  Endocrine Pancreas

    ·  Adrenal Cortex

    ·  Adrenal Medulla

    ·  Multiple Endocrine Neoplasia (MEN) Syndromes

    ·  Suggested Readings

    ·  Chapter 21 Bones, Joints, and Soft Tissue Tumors

    ·  Bone

    ·  Joints

    ·  Soft Tissue Tumors

    ·  Suggested Readings

    ·  Chapter 22 Peripheral Nerves and Muscles

    ·  Disorders of Peripheral Nerves

    ·  Disorders of Neuromuscular Junction

    ·  Disorders of Skeletal Muscle

    ·  Peripheral Nerve Sheath Tumors

    ·  Suggested Readings

    ·  Chapter 23 Central Nervous System

    ·  Edema, Herniation, and Hydrocephalus

    ·  Cerebrovascular Diseases

    ·  Central Nervous System Trauma

    ·  Congenital Malformations and Perinatal Brain Injury

    ·  Infections of the Nervous System

    ·  Diseases of Myelin

    ·  Genetic Metabolic Diseases

    ·  Acquired Metabolic and Toxic Disturbances

    ·  Neurodegenerative Diseases

    ·  Tumors

    ·  Suggested Readings

    ·  Chapter 24 Skin

    ·  Acute Inflammatory Dermatoses

    ·  Chronic Inflammatory Dermatoses

    ·  Infectious Dermatoses

    ·  Blistering (Bullous) Disorders

    ·  Tumors of the Skin

    ·  Suggested Readings

  • 40000lei 330.00 lei

    Description:

    The foremost text in this complex and fast-changing field, Medical Microbiology, 9th Edition, provides concise, up-to-date, and understandable explanations of key concepts in medical microbiology, immunology, and the microbes that cause human disease. Clear, engaging coverage of basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology help you master the essentials of microbiology―effectively preparing you for your coursework, exams, and beyond.

    Features significant new information on the human microbiome and its influence on the immune and other body systems, and new developments in microbial diagnosis, treatment, diseases, and pathogens.

    Updates every chapter with state-of-the-art information and current literature citations.

    Summarizes detailed information in tabular format rather than in lengthy text.

    Provides review questions at the end of each chapter that correlate basic science with clinical practice.

    Features clinical cases that illustrate the epidemiology, diagnosis, and treatment of infectious diseases.

    Introduces microbe chapters with summaries and trigger words for easy review.

    Highlights the text with clear, colorful figures, clinical photographs, and images that help you visualize the clinical presentation of infections.

    Offers additional study features online, including 200 self-assessment questions, microscopic images of the microbes, videos, and a new integrating chapter that provides hyperlinks between the microbes, the organ systems that they affect, and their diseases.

     

    Table of Contents:

     

    Section 1. Introduction

    1. Introduction to Medical Microbiology

    Historical Perspective

    Viruses

    Bacteria

    Fungi

    Parasites

    Immunology

    Diagnostic Microbiology

    Microbiology and Immunology in the Clinic

    Summary

    2. Human Microbiome in Health and Disease

    Human Microbiome Project

    Core Microbiome

    Evolution of the Microbiome and Normal Flora

    Role of the Microbiome in Disease

    Diagnostics and Therapeutics

    Probiotics

    Perspective

    3. Sterilization, Disinfection, and Antisepsis

    Sterilization

    Disinfection

    Antisepsis

    Mechanisms of Action

    Section 2. General Principles of Laboratory Diagnosis

    4. Microscopy and In Vitro Culture

    Microscopy

    In Vitro Culture

    5. Molecular Diagnosis

    Nonamplified Nucleic Acid Probes

    Nucleic Acid Analysis

    Protein Analysis

    6. Serologic Diagnosis

    Antibodies

    Methods of Detection

    Immunoassays for Cell-Associated Antigen (Immunohistology)

    Immunoassays for Antibody and Soluble Antigen

    Serology

    Section 3. Basic Concepts in the Immune Response

    7. Elements of Host Protective Responses

    Soluble Activators and Stimulators of Innate and Immune Functions

    Cells of the Immune Response

    8. Innate Host Responses

    Barriers to Infection

    Soluble Components of Innate Responses

    Cellular Components of Innate Responses

    Activation of Innate Cellular Responses

    Normal Flora–Associated Responses

    Inflammation

    Bridge to Antigen-Specific Immune Responses

    9. Antigen-Specific Immune Responses

    Immunogens, Antigens, and Epitopes

    T Cells

    Cell-Surface Receptors of T Cells

    Development of T Cells

    Initiation of T-Cell Responses

    Activation of CD4 T Cells and Their Response to Antigen

    CD8 T Cells

    INNATE T Cells

    B Cells and Humoral Immunity

    B cells

    Immunoglobulin Types and Structures

    Immunogenetics

    Antibody Response

    10. Immune Responses to Infectious Agents

    Antibacterial Responses

    Antiviral Responses

    Specific Immune Responses to Fungi

    Specific Immune Responses to Parasites

    Other Immune Responses

    Immunopathogenesis

    Autoimmune Responses

    Immunodeficiency

    11. Antimicrobial Vaccines

    Types of Immunizations

    Immunization Programs

    Section 4. Bacteriology

    12. Bacterial Classification, Structure, and Replication

    Differences between Eukaryotes and Prokaryotes

    Bacterial Classification

    Bacterial Structure

    Structure and Biosynthesis of the Major Components of the Bacterial Cell Wall

    Cell Division

    Spores

    13. Bacterial Metabolism and Genetics

    Bacterial Metabolism

    Human Bacterial Metabolism

    Bacterial Genes and Expression

    Bacterial Genetics

    14. Mechanisms of Bacterial Pathogenesis

    Entry into the Human Body

    Colonization, Adhesion, and Invasion

    Pathogenic Actions of Bacteria

    Immunopathogenesis

    Mechanisms for Escaping Host Defenses

    Summary

    15. Role of Bacteria in Disease

    16. Laboratory Diagnosis of Bacterial Diseases

    Specimen Collection, Transport, and Processing

    Bacterial Detection and Identification

    Antimicrobial Susceptibility Tests

    17. Antibacterial Agents

    Inhibition of Cell Wall Synthesis

    Inhibition of Protein Synthesis

    Inhibition of Nucleic Acid Synthesis

    Other Antibiotics

    18. Staphylococcus and Related Gram-Positive Cocci

    Physiology and Structure

    Pathogenesis and Immunity

    Epidemiology

    Clinical Diseases

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    19. Streptococcus and Enterococcus

    Streptococcus pyogenes

    Streptococcus agalactiae

    Other β-Hemolytic Streptococci

    Viridans Streptococci

    Streptococcus pneumoniae

    Enterococcus

    20. Bacillus

    Bacillus anthracis

    Bacillus cereus

    21. Listeria and Related Gram-Positive Bacteria

    Listeria monocytogenes

    Erysipelothrix rhusiopathiae

    Corynebacterium diphtheriae

    22. Mycobacterium and Related Acid-Fast Bacteria

    • Physiology and Structure of Mycobacteria

    • Mycobacterium Tuberculosis

    • Other Slow-Growing Mycobacteria

    • Rapidly Growing Mycobacteria

    • Nocardia

    • Other Weakly Acid-Fast Bacteria

    23. Neisseria and Related Genera

    Neisseria gonorrhoeae and Neisseria meningitidis

    Other Neisseria Species

    24. Haemophilus and Related Bacteria

    Haemophilus

    25. Enterobacteriaceae

    General Properties

    Escherichia coli

    Salmonella

    Shigella

    Yersinia

    Other Enterobacteriaceae

    Other General Properties

    26. Vibrio and Related Bacteria

    Vibrio

    Aeromonas

    27. Pseudomonas and Related Bacteria

    Pseudomonas

    Burkholderia

    Stenotrophomonas maltophilia

    Acinetobacter

    Moraxella

    28. Campylobacter and Helicobacter

    Campylobacter

    Helicobacter

    29. Miscellaneous Gram-Negative Rods

    Bartonella

    Bordetella

    Other Bordetella Species

    Brucella

    Cardiobacterium

    Francisella

    Legionella

    Streptobacillus

    30. Clostridium

    Clostridium difficile

    Clostridium perfringens

    Clostridium tetani

    Clostridium botulinum

    Other Clostridial Species

    31. Non–Spore-Forming Anaerobic Bacteria

    Anaerobic Gram-Positive Cocci

    Answers

    Anaerobic Gram-Positive Rods

    Anaerobic Gram-Negative Cocci

    Anaerobic Gram-Negative Rods

    32. Treponema, Borrelia, and Leptospira

    Treponema

    Borrelia

    Leptospira

    33. Mycoplasma

    Physiology and Structure

    Pathogenesis and Immunity

    Answers

    Epidemiology

    Clinical Diseases

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    34. Rickettsia, Ehrlichia, and Related Bacteria

    Rickettsiaceae

    Anaplasmataceae

    Coxiellaceae

    35. Chlamydia

    Physiology and Structure

    Section 5. Virology

    36. Viral Classification, Structure, and Replication

    Classification

    Virion Structure

    Viral Replication

    Viral Genetics

    Viral Vectors for Therapy

    37. Mechanisms of Viral Pathogenesis

    Basic Steps in Viral Disease

    Infection of the Target Tissue

    Viral Pathogenesis

    Viral Disease

    Epidemiology

    Control of Viral Spread

    38. Role of Viruses in Disease

    Viral Diseases

    Chronic and Potentially Oncogenic Infections

    Infections in Immunocompromised Patients

    Congenital, Neonatal, and Perinatal Infections

    39. Laboratory Diagnosis of Viral Diseases

    Specimen Collection

    Cytology

    Electron Microscopy

    Viral Isolation and Growth

    Detection of Viral Genetic Material

    Detection of Viral Proteins

    Viral Serology

    40. Antiviral Agents and Infection Control

    Targets for Antiviral Drugs

    Nucleoside Analogs

    Nonnucleoside Polymerase Inhibitors

    Protease Inhibitors

    Antiinfluenza Drugs

    Immunomodulators

    Infection Control

    41. Papillomaviruses and Polyomaviruses

    Human Papillomaviruses

    Polyomaviridae

    42. Adenoviruses

    Structure and Replication

    Pathogenesis and Immunity

    Epidemiology

    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    Therapeutic Adenoviruses

    43. Human Herpesviruses

    Structure of Herpesviruses

    Herpesvirus Replication

    Herpes Simplex Virus

    Varicella-Zoster Virus

    Epstein-Barr Virus

    Cytomegalovirus

    Human Herpesviruses 6 and 7

    Other Human Herpesviruses

    44. Poxviruses

    Structure and Replication

    Pathogenesis and Immunity

    Epidemiology

    Clinical Syndromes

    45. Parvoviruses

    Structure and Replication

    Pathogenesis and Immunity

    Epidemiology

    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    46. Picornaviruses

    Structure

    Replication

    Enteroviruses

    Rhinoviruses

    47. Coronaviruses and Noroviruses

    Coronaviruses

    Noroviruses

    48. Paramyxoviruses

    Structure and Replication

    Measles Virus

    Parainfluenza Viruses

    Mumps Virus

    Respiratory Syncytial Virus

    Human Metapneumovirus

    Nipah and Hendra Viruses

    49. Orthomyxoviruses

    Structure and Replication

    Pathogenesis and Immunity

    Epidemiology

    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    50. Rhabdoviruses, Filoviruses, and Bornaviruses

    Rhabdoviruses

    Filoviruses

    Borna Disease Virus

    51. Reoviruses

    Structure

    Replication

    Rotaviruses

    Orthoreoviruses (Mammalian Reoviruses)

    Coltiviruses and Orbiviruses

    52. Togaviruses and Flaviviruses

    Alphaviruses and Flaviviruses

    Rubella Virus

    53. Bunyaviridae and Arenaviridae

    Bunyaviridae

    Arenaviruses

    54. Retroviruses

    Classification

    Structure

    Replication

    Human Immunodeficiency Virus

    Human T-Cell Lymphotropic Virus and Other Oncogenic Retroviruses

    Endogenous Retroviruses

    55. Hepatitis Viruses

    Hepatitis A Virus

    Hepatitis B Virus

    Hepatitis C and G Viruses

    Hepatitis G Virus

    Hepatitis D Virus

    Hepatitis E Virus

    56. Prion Diseases

    Structure and Physiology

    Pathogenesis

    Epidemiology

    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    Section 6. Mycology

    57. Fungal Classification, Structure, and Replication

    The Importance of Fungi

    Fungal Taxonomy, Structure, and Replication

    Ascomycota (Ascomycetes)

    Basidiomycota (Basidiomycetes)

    Glomerulomycota (Mucormycetes, formerly Zygomycetes)

    Microspora (Microsporidia)

    Classification of Human Mycoses

    Summary

    58. Pathogenesis of Fungal Disease

    Primary Fungal Pathogens

    Opportunistic Pathogens

    59. Role of Fungi in Disease

    60. Laboratory Diagnosis of Fungal Disease

    Clinical Recognition of Fungal Infections

    Conventional Laboratory Diagnosis

    Immunologic, Molecular, and Biochemical Markers for Direct Detection of Invasive Fungal Infections

    61. Antifungal Agents

    Systemically Active Antifungal Agents

    Topical Antifungal Agents

    Investigational Antifungal Agents

    Combinations of Antifungal Agents in the Treatment of Mycoses

    Mechanisms of Resistance to Antifungal Agents

    62. Superficial and Cutaneous Mycoses

    Superficial Mycoses

    Cutaneous Mycoses

    63. Subcutaneous Mycoses

    Lymphocutaneous Sporotrichosis

    Chromoblastomycosis

    Eumycotic Mycetoma

    Subcutaneous Entomophthoromycosis

    Subcutaneous Phaeohyphomycosis

    64. Systemic Mycoses Caused by Dimorphic Fungi

    Blastomycosis

    Coccidioidomycosis

    Emergomycosis and Adiaspiromycosis

    Histoplasmosis

    Paracoccidioidomycosis

    Talaromycosis (Penicilliosis) marneffei

    65. Opportunistic Mycoses

    Candidiasis

    Opportunistic Mycoses Caused by Cryptococcus Neoformans and Other Noncandidal Yeastlike Fungi

    Microsporidia

    Aspergillosis

    Mucormycosis

    Mycoses Caused by Other Hyaline Molds

    Phaeohyphomycosis

    Pneumocystosis

    66. Fungal and Fungal-Like Infections of Unusual or Uncertain Etiology

    Adiaspiromycosis

    Chlorellosis

    Lacaziosis (Lobomycosis)

    Protothecosis

    Pythiosis Insidiosi

    Lagenidiosis

    Rhinosporidiosis

    Section 7. Parasitology

    67. Parasitic Classification, Structure, and Replication

    Importance of Parasites

    Classification and Structure

    Physiology and Replication

    Summary

    68. Pathogenesis of Parasitic Diseases

    Exposure and Entry

    Adherence and Replication

    Cell and Tissue Damage

    Disruption, Evasion, and Inactivation of Host Defenses

    69. Role of Parasites in Disease

    70. Laboratory Diagnosis of Parasitic Disease

    Parasite Life Cycle as an Aid in Diagnosis

    General Diagnostic Considerations

    Parasitic Infections of the Intestinal and Urogenital Tracts

    Parasitic Infections of Blood and Tissue

    Alternatives to Microscopy

    71. Antiparasitic Agents

    Targets for Antiparasite Drug Action

    Drug Resistance

    Antiparasitic Agents

    72. Intestinal and Urogenital Protozoa

    Amebae (Amoebozoa)

    Ciliates (Metamonada [Formerly Flagellates] and Ciliophora)

    Sporozoa (Apicomplexa)

    73. Blood and Tissue Protozoa

    Plasmodium Species

    Babesia Species

    Toxoplasma gondii

    Sarcocystis lindemanni

    Free-Living Amebae

    Leishmania

    Trypanosomes

    74. Nematodes

    Enterobius vermicularis

    Ascaris lumbricoides

    Toxocara and Baylisascaris

    Trichuris trichiura

    Hookworms

    Strongyloides stercoralis

    Trichinella spiralis

    Wuchereria bancrofti and Brugia malayi

    Loa loa

    Mansonella Species

    Onchocerca volvulus

    Dirofilaria immitis

    Dracunculus medinensis

    75. Trematodes

    Fasciolopsis buski

    Fasciola hepatica

    Clonorchis sinensis

    Paragonimus westermani

    Schistosomes

    76. Cestodes

    Taenia solium

    Cysticercosis

    Taenia saginata

    Diphyllobothrium latum

    Sparganosis

    Echinococcus granulosus

    Echinococcus multilocularis

    Hymenolepis nana

    Hymenolepis diminuta

    Dipylidium caninum

    77. Arthropods

    Myriapoda

    Crustacea

    Pentastomida

    Chelicerata (Arachnida)

    Hexapoda (Insecta)

    Answers

    Index

     


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    La comanda in aproximativ 4 saptamani
    40400lei 380.00 lei

    Principles of Rubin's Pathology, Seventh Edition distills the renowned coverage of Rubin's Pathology, Seventh Edition into a focused, approachable guide to the essentials of pathology. This resource introduces principles and mechanisms of pathology, followed by organ-specific information, extracting key information on pathogenesis, epidemiology, and clinical features of diseases. Detailed images clarify challenging content, and companion online resources enable students to learn on the go and confidently prepare for exams. This edition is optimized for students seeking only the most critical information, making it an ideal resource for international medical schools, PA, pharmacy, nursing, and allied health programs. Streamlined content emphasizes essential concepts, including the use of bold terms and bulleted lists to emphasize key points, for the most efficient study of pathology available. Illustrations, photomicrographs, and clinical photographs clarify challenging content and represent the pathogeneses of disease. Highlighted boxes and helpful graphic icons identify Pathogenesis, Pathology, Epidemiology, and Clinical Features sections. Globally sourced content reflects an international spectrum of current practices and approaches. Online resources including new slide-based histopathology lectures presented by Dr. Rubin, original animations, and fully searchable text make learning more engaging and efficient. eBook available for purchase. Fast, smart, and convenient, today's eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and more.

    ·  Contents

    ·  1. Cell Adaptation, Injury, Death, and Aging David S. Strayer, Emanuel Rubin, David Lombard

    ·  2. Inflammation and Repair Hedwig S. Murphy, Kendra Iskander, David S. Strayer, Daniel G. Remick, Gregory C. Sephel, Jeffrey M. Davidson

    ·  3. Immunopathology Jeffrey S. Warren, David S. Strayer, Philip L. Cohen, Sergio A. Jimenez

    ·  4. Neoplasia David S. Strayer, Emanuel Rubin

    ·  5. Developmental and Genetic Diseases Linda A. Cannizzaro

    ·  6. Infectious and Parasitic Diseases David A. Schwartz

    ·  7. The Amyloidoses Philip Hawkins

    ·  8. Blood Vessels and Hemodynamic Disorders Avrum I. Gotlieb, Amber Chang Liu, Bruce M. McManus, Michael F. Allard, Robert Yanagawa

    ·  9. Heart Jeffrey E. Saffitz

    ·  10. The Respiratory System Mary Beth Beasley, William D. Travis

    ·  11. The Gastrointestinal Tract Leana Guerin, Frank Mitros

    ·  12. The Liver and Biliary System Arief A. Suriawinata, Swan N. Thung

    ·  13. The Exocrine Pancreas David S. Klimstra, Edward B. Stelow

    ·  14. The Kidney J. Charles Jennette

    ·  15. The Lower Urinary Tract and Male Reproductive System Ivan Damjanov, Peter A. McCue

    ·  16. The Female Reproductive Tract George L. Mutter, Jaime Prat, David A. Schwartz

    ·  17. The Breast Anna Marie Mulligan, Frances P. O’Malley

    ·  18. Hematopathology Riccardo Valdez, Mary M. Zutter, Shauying Li, Alina Dulau Florea, Bruce M. McManus, Michael F. Allard, Robert Yanagawa

    ·  19. Endocrine System, Diabetes, and Nutritional Diseases Maria J. Merino, David S. Klimstra, Edward B. Stelow, David S. Strayer, Emanuel Rubin, Kevin Jon Williams, Elias S. Siraj

    ·  20. The Skin Ronnie M. Abraham, Emily Y. Chu, David E. Elder

    ·  21. The Head and Neck Diane L. Carlson

    ·  22. Bones, Joints, and Soft Tissue Roberto A. Garcia, Elizabeth G. Dostco, Michael J. Klein, Alan L. Schiller

    ·  23. Skeletal Muscle Lawrence C. Kenyon, Thomas W. Bouldin

    ·  24. The Central Nervous System and Eye Gregory N. Fuller, J. Clay Goodman, Gordon K. Klintworth

    ·  25. Traumatic and Environmental Injury Marc S. Micozzi, David S. Strayer, Emanuel Rubin

     

     


  • 50500lei 445.00 lei

     

    Description:

    Learn the essential concepts of major diseases/disorders and disease processes. Gould’s Pathophysiology for the Health Professions, 6th Edition is a concise, easy-to-understand introduction to the fundamentals of pathophysiology. Continuing in its well-known tradition of readability and vivid, full-color illustrations, the text is updated with the latest research and trends in human disease. Disorders are described by body system, with coverage of the interactions between systems, and special features help you to apply the material to real-life situations. No matter which healthcare field you may enter, this book provides solid preparation for the conditions you may encounter in clinical practice.

    Features:

    Updated graphics help you recognize and identify various concepts and specific disorders through enhanced flowcharts, photos, and illustrations.

    Concise and readable approach includes the information you need without overwhelming you, even if you have a limited scientific background.

    Format for individual disorder discussions includes 1) background, 2) pathophysiology, 3) etiology, 4) signs and symptoms, 5) diagnoses, 6) possible related complications/disorders, and 7) treatments/research.

    UNIQUE! Apply Your Knowledge questions ask you to use what you’ve learned to predict What can go wrong with this structure or system, transitioning you from normal anatomy and physiology into pathophysiology.

    UNIQUE! Think About questions alert you to important points and help with self-evaluation, test preparation, and review.

    Warning Signs boxes help in identifying the pre-emptive signs of physiologic events such as strokes.

    Emergency Treatment boxes give step-by-step instructions to follow for emergencies such as shock, cardiac arrest, and pneumothorax.

    Research boxes discuss new developments, problem areas of pathophysiology, and complications associated with research.

    Key terms, learning objectives, and bulleted chapter summaries help you focus on key concepts and information.

    New To This Edition:

    NEW! All chapters updated to include new data on major diseases and other changes in guidelines and the literature, reflecting latest developments in pathophysiology including, updated drug therapy content, expanded coverage of viruses, new cancer treatments, new research on the links between mental health and biochemical/physiologic factors, and much more!

    NEW! Streamlined narrative content enhances the readability of imperative information.




    Table Of Contents:

    Section I: Pathophysiology: Background and Overview
    1. Introduction to Pathophysiology
    2. Fluid, Electrolyte, and Acid-Base Imbalances
    3. Introduction to Basic Pharmacology and Other Common Therapies
    4. Pain

    Section II: Defense/Protective
    5. Inflammation and Healing
    6. Infection
    7. Immunity

    Section III: Pathophysiology of Body Systems
    8. Skin Disorders
    9. Musculoskeletal Disorders
    10. Blood and the Circulatory System
    11. Lymphatic System Disorders
    12. Cardiovascular System Disorders
    13. Respiratory System Disorders
    14. Neurological Disorders
    15. Eyes, Ears and Other Sensory Organs
    16. Endocrine Disorders
    17. Digestive System Disorders
    18. Urinary System Disorders
    19. Reproductive System Disorders
    20. Neoplasms and Cancer

    Section IV: Factors Contributing to Pathophysiology
    21. Congenital and Genetic Disorders
    22. Complications Due to Pregnancy
    23. Complications Due to Adolescence
    24. Complications Due to Aging

    Section V: Environmental Factors and Pathophysiology
    25. Immobility and Associated Problems
    26. Stress and Associated Problems
    27. Substance Abuse and Associated Problems
    28. Environmental Hazards and Associated Problems

    Appendixes: Ready References
    Ready Reference 1: Body Planes, Cavities, Regions, Fluid Compartments, and Body Movements
    Ready Reference 2: Anatomic Terms
    Ready Reference 3: Conversion Tables
    Ready Reference 4: Common Abbreviations and Acronyms
    Ready Reference 5: Common Diagnostic Studies and Tests
    Ready Reference 6: Example of a Medical History
    Ready Reference 7: Disease Index
    Ready Reference 8: Drug Index
    Ready Reference 9: Additional Resources

       

     

  • Clinical Oral Medicine and Pathology
    La comanda in aproximativ 4 saptamani
    50500lei 450.00 lei

     

    Following on the favorable reception of the first edition, the authors have thoroughly revised and updated the second edition of this resourceful clinical handbook. The book has been well received internationally by a wide audience of clinicians, including general dentists, oral surgeons, otolaryngologists, primary care physicians, nurse practitioners, dental hygienists, physician assistants, and dermatologists, and sales have been strong among students and post-graduate residents training in medical, dental, and allied health fields, supporting the versatility of this work and serving as testimony to its value in both the academic and private practice arenas.   Several key updates and improvements have been made to the second edition. All informational content has been updated to ensure accuracy and relevance, particularly in the rapidly evolving fields of oncology and pharmacology. A new chapter has been added entitled “Oral Sequelae of Cancer and Cancer Therapy” which better organizes and consolidates previous content while expanding on topics such as targeted therapies and hematopoietic stem cell transplantation. Additional clinical images have been included throughout the book so that the full clinical spectrum of any given condition is well-represented. Furthermore, the print quality, as well as the positioning and layout of the clinical images has been improved for optimal utility. Lastly, the summary boxes that follow each condition have been reconfigured with color-coded icons for improved definition, ease of use and cross-referencing. Clinical Oral Medicine and Pathology, Second Edition will continue to serve as an authoritative contemporary resource for clinicians seeking guidance in the diagnosis and management of oral diseases.

     

    Table of contents (13 chapters)

     

    ·         Normal Anatomy

    Pages 1-16

    Bruch, Jean M. (et al.)

    ·         Variants of Normal and Common Benign Conditions

    Pages 17-30

    Bruch, Jean M. (et al.)

    ·         Diagnostic Tests and Studies

    Pages 31-43

    Bruch, Jean M. (et al.)

    ·         White Lesions

    Pages 45-55

    Bruch, Jean M. (et al.)

    ·         Immune-Mediated and Allergic Conditions

    Pages 57-77

    Bruch, Jean M. (et al.)

    ·         Pigmented Lesions

    Pages 79-93

    Bruch, Jean M. (et al.)

    ·         Oral Infections

    Pages 95-120

    Bruch, Jean M. (et al.)

    ·         Salivary Gland Disease

    Pages 121-133

    Bruch, Jean M. (et al.)

    ·         Oral Cancer

    Pages 135-151

    Bruch, Jean M. (et al.)

    ·         Orofacial Pain Conditions

    Pages 153-162

    Bruch, Jean M. (et al.)

    ·         Oral Manifestations of Systemic Disease

    Pages 163-180

    Bruch, Jean M. (et al.)

    ·         Oral Sequelae of Cancer Therapy

    Pages 181-196

    Bruch, Jean M. (et al.)

    ·         Prescribing Guidelines for Commonly Used Medications

    Pages 197-202

    Bruch, Jean M. (et al.)

     

  • 56000lei 460.00 lei

     

    Description:

    Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, 10th Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. This superb learning package also includes an enhanced eBook with a full complement of ancillary content on Student Consult.

    Provides uniquely authoritative and readable coverage, ideal for USMLE or specialty board preparation, as well as for coursework.

    Covers the hot topics you need to know about, including novel therapies for hepatitis C, classification of lymphomas, unfolded protein response, non-apoptotic pathways of cell death, coronavirus infections, liquid biopsy for cancer detection, regulation of iron absorption, clonal hematopoiesis and atherosclerosis, thrombotic microangiopathies, heparin-induced thrombocytopenias, inflammatory myopathies, genetic tools for treatment of cystic fibrosis, and many more. 

    Uses an outstanding full-color, user-friendly design to simplify your study and quickly direct you to the information you need to know, with learning features such as boldface overviews at the beginning of each section, key concepts boxes, suggested readings, schematic diagrams that illustrate complex concepts, and new gross and microscopic figures for clarity of morphology.

    Brings you up to date with the latest information in molecular and genetic testing, mechanisms of disease, personalized medicine and its impact on treatment of human diseases, the role of microbiome and metabolome in non-communicable diseases, and much more.

    Provides access to a wealth of interactive ancillaries online: pathology case studies, videos, self-assessment questions, Targeted Therapy boxes that discuss drug therapy for specific diseases, interactive cases, and more.

    Evolve Instructor site with an image and test bank is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.

     

     

    Table of Contents:

     

    Chapter 1 The Cell as a Unit of Health and Disease

    The Genome

    Cellular Housekeeping

    Cellular Metabolism and Mitochondrial Function

    Cellular Activation

    Growth Factors and Receptors

    Extracellular Matrix

    Maintaining Cell Populations

    Suggested Readings

     

    Chapter 2 Cell Injury, Cell Death, and Adaptations

    Introduction to Pathology

    Overview of Cellular Responses to Stress and Noxious Stimuli

    Reversible Cell Injury

    Cell Death

    Mechanisms of Cell Injury

    Clinicopathologic Correlations: Selected Examples of Cell Injury and DEATH

    Adaptations of Cellular Growth and Differentiation

    Intracellular Accumulations

    Pathologic Calcification

    Cellular Aging

    Suggested Readings

     

    Chapter 3 Inflammation and Repair

    Overview of Inflammation: Definitions and General Features

    Acute Inflammation

    Chronic Inflammation

    Systemic Effects of Inflammation

    Tissue Repair

    Suggested Readings

     

    Chapter 4 Hemodynamic Disorders, Thromboembolic Disease, and Shock

    Edema and Effusions

    Hyperemia and Congestion

    Hemostasis, Hemorrhagic Disorders, and Thrombosis

    Embolism

    Infarction

    Shock

    Suggested Readings

     

    Chapter 5 Genetic Disorders

    Genes and Human Diseases

    Mendelian Disorders

    Complex Multigenic Disorders

    Chromosomal Disorders

    Single-Gene Disorders With Nonclassic Inheritance

    Molecular Genetic Diagnosis

    Acknowledgment

    Suggested Readings

     

    Chapter 6 Diseases of the Immune System

    The Normal Immune Response

    Hypersensitivity: Immunologically Mediated Tissue Injury

    Autoimmune Diseases

    Rejection of Tissue Transplants

    Immunodeficiency Diseases

    Amyloidosis

    Suggested Readings

     

    Chapter 7 Neoplasia

    Nomenclature

    Characteristics of Benign and Malignant Neoplasms

    Epidemiology of Cancer

    Molecular Basis of Cancer: Role of Genetic and Epigenetic Alterations

    Carcinogenic Agents and Their Cellular Interactions

    Clinical Aspects of Neoplasia

    Suggested Readings

     

    Chapter 8 Infectious Diseases

     

    General Principles of Microbial Pathogenesis

    Viral Infections

    Bacterial Infections

    Fungal Infections

    Parasitic Infections

    Sexually Transmitted Infections

    Emerging Infectious Diseases

    Special Techniques for Diagnosing Infectious Agents

    Suggested Readings

     

    Chapter 9 Environmental and Nutritional Diseases

    Health Effects of Climate Change

    Toxicity of Chemical and Physical Agents

    Environmental Pollution

    Occupational Health Risks: Industrial and Agricultural Exposures

    Effects of Alcohol

    Injury by Therapeutic Drugs and Drugs of Abuse

    Injury by Physical Agents

    Nutritional Diseases

    Suggested Readings

     

    Chapter 10 Diseases of Infancy and Childhood

    Congenital Anomalies

    Prematurity and Fetal Growth Restriction

    Perinatal Infections

    Fetal Hydrops

    Inborn Errors of Metabolism and Other Genetic Disorders

    Sudden Infant Death Syndrome

    Tumors and Tumorlike Lesions of Infancy and Childhood

    Suggested Readings

     

    Chapter 11 Blood Vessels

    Vascular Structure and Function

    Vascular Anomalies

    Vascular Wall Response to Injury

    Hypertensive Vascular Disease

    Arteriosclerosis

    Atherosclerosis

    Aneurysms and Dissection

    Vasculitis

    Disorders of Blood Vessel Hyperreactivity

    Veins and Lymphatics

    Vascular Tumors

    Pathology of Vascular Intervention

    Suggested Readings

     

    Chapter 12 The Heart

    Cardiac Structure and Specializations

    Overview of Cardiac Pathophysiology

    Heart Failure

    Cardiac Development

    Congenital Heart Disease

    Ischemic Heart Disease

    Arrhythmias

    Hypertensive Heart Disease

    Valvular Heart Disease

    Cardiomyopathies

    Pericardial Disease

    Tumors of the Heart

    Cardiac Transplantation

    Cardiac Devices

    Suggested Readings

     

    Chapter 13 Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus

    Normal Hematopoiesis

    Disorders of White Cells

    Spleen

    Thymus

    Suggested Readings

     

    Chapter 14 Red Blood Cell and Bleeding Disorders

    Anemias

    Polycythemia

    Bleeding Disorders: Hemorrhagic Diatheses

    Suggested Readings

     

    Chapter 15 The Lung

    Congenital Anomalies

    Atelectasis (Collapse)

    Pulmonary Edema

    Acute Lung Injury and Acute Respiratory Distress Syndrome (Diffuse Alveolar Damage)

    Obstructive and Restrictive Lung Diseases

    Obstructive Lung Diseases

    Chronic Diffuse Interstitial (Restrictive) Diseases

    Diseases of Vascular Origin

    Pulmonary Infections

    Lung Transplantation

    Tumors

    Pleura

    Suggested Readings

     

    Chapter 16 Head and Neck

    Oral Cavity

    Upper Airways

    Ears

    Neck

    Salivary Glands

    Suggested Readings

     

    Chapter 17 The Gastrointestinal Tract

    Congenital Abnormalities

    Esophagus

    Stomach

    Small Intestine and Colon

    Peritoneal Cavity

    Suggested Readings

     

    Chapter 18 Liver and Gallbladder

    The Liver and Bile Ducts

    Gallbladder

    Suggested Readings

     

    Chapter 19 The Pancreas

    Congenital Anomalies

    Pancreatitis

    Nonneoplastic Cysts

    Neoplasms

    Suggested Readings

     

    Chapter 20 The Kidney

    Clinical Manifestations of Renal Diseases

    Glomerular Diseases

    Tubular and Interstitial Diseases

    Vascular Diseases

    Congenital and Developmental Anomalies

    Cystic Diseases of the Kidney

    Urinary Tract Obstruction (Obstructive Uropathy)

    Urolithiasis (Renal Calculi, Stones)

    Neoplasms of the Kidney

    Suggested Readings

     

    Chapter 21 The Lower Urinary Tract and Male Genital System

    The Lower Urinary Tract

    The Male Genital Tract

    Suggested Readings

     

    Chapter 22 The Female Genital Tract

    Vulva

    Vagina

    Cervix

    Body of Uterus and Endometrium

    Ovaries

    Gestational and Placental Disorders

    Suggested Readings

     

    Chapter 23 The Breast

    Disorders of Development

    Clinical Presentations of Breast Disease

    Inflammatory Disorders

    Benign Epithelial Lesions

    Carcinoma of the Breast

    Stromal Tumors

    Other Malignant Tumors of the Breast

    Suggested Readings

     

    Chapter 24 The Endocrine System

    Pituitary Gland

    Thyroid Gland

    Parathyroid Glands

    The Endocrine Pancreas

    Adrenal Glands

    Multiple Endocrine Neoplasia Syndromes

    Pineal Gland

    Suggested Readings

     

    Chapter 25 The Skin

    The Skin: More Than a Mechanical Barrier

    Disorders of Pigmentation and Melanocytes

    Benign Epithelial Tumors

    Adnexal (Appendage) Tumors

    Premalignant and Malignant Epidermal Tumors

    Tumors of the Dermis

    Tumors of Cellular Migrants to the Skin

    Disorders of Epidermal Maturation

    Acute Inflammatory Dermatoses

    Chronic Inflammatory Dermatoses

    Blistering (Bullous) Diseases

    Disorders of Epidermal Appendages

    Panniculitis

    Infection

    Suggested Readings

     

    Chapter 26 Bones, Joints, and Soft Tissue Tumors

    Bone

    Joints

    Soft Tissue Tumors

    Suggested Readings

     

    Chapter 27 Peripheral Nerves and Skeletal Muscles

    Diseases of Peripheral Nerves

    Diseases of the Neuromuscular Junction

    Diseases of Skeletal Muscle

    Peripheral Nerve Sheath Tumors

    Suggested Readings

     

    Chapter 28 The Central Nervous System

    Cellular Pathology of the Central Nervous System

    Cerebral Edema, Hydrocephalus, Raised Intracranial Pressure, and Herniation

    Malformations and Developmental Disorders

    Perinatal Brain Injury

    Trauma

    Cerebrovascular Disease

    Infections

    Demyelinating Diseases

    Neurodegenerative Diseases

    Genetic Metabolic Diseases

    Toxic and Acquired Metabolic Diseases

    Tumors

    Acknowledgment

    Suggested Readings

     

    Chapter 29 The Eye

    Orbit

    Eyelid

    Conjunctiva

    Sclera

    Cornea

    Anterior Segment

    Uvea

    Retina and Vitreous

    Optic Nerve

    The End-Stage Eye: Phthisis Bulbi

    Suggested Readings

    Index

     

  • 56000lei 480.00 lei

    This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis.

    Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists and researchers with an interest in kidney diseases.

  • 550.00 lei

    Dependable, current, and complete, Robbins and Cotran Pathologic Basis of Disease, 9th Edition is the perennially best-selling text that you'll use long after your medical student days are behind you. A world-class author team headed by Drs. Vinay Kumar, Abul Abbas, and Jon Aster, delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. High-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more.

  • 63500lei 550.00 lei

    Features

    • Presents a logical and systematic approach to lymph node biopsies
    • Discusses both classical and less well-known features of individual disease processes
    • Includes differential diagnoses of lymph node biopsy specimens
    • Contains more than 300 high-quality histological colour photograph and boxes for quick reference
    • Features succinct and easy-to-read text that allows you to find information fast

    Summary

    Diagnostic Lymph Node Pathology presents a logical and systematic approach to lymph node biopsies and guides general pathologists and haematopathologists alike through the maze of differential diagnoses, enabling them to reach an accurate diagnosis.

    The book is presented in an easy-to-read format and contains boxes for quick reference detailing the clinical, morphological, immunohistochemical, and genetic features of each entity. Thoroughly revised, the third edition also includes more than 300 high-quality histological colour photographs along with updated references.

    This edition covers both classical and less well-known features of individual disease processes. It is a valuable guide for both professionals and trainees.

  • 63000lei 560.00 lei

     

    This book provides a quick, pattern-based reference for interpreting histologic changes in non-neoplastic liver. It is designed to guide the reader based on morphologic pattern and basic clinical information. Each chapter covers a broad but identifiable pat­tern of pathologic liver findings (e.g., “portal inflammation” or “steatosis”) and discusses the major disease entities that manifest as such a pattern. As liver biopsies can be complex and daunting, such an approach should improve the reader’s ability to identi­fy a likely diagnosis or differential and to distinguish among the possible disease enti­ties. Sample reports at the end of each chap­ter offer guidance on how to sign out cases.

     Non-Neoplastic Liver Pathology: A Patholo­gist’s Survival Guide will be of value to practicing pathologists without specialized training in hepatic pathology, pathology residents and fellows trying to learn the basics of non-neoplastic liver pathology, and hepatologists interested in reviewing liver biopsies with pathologists

     

     

    Table of contents:

     

    Introduction

    Pages 1-3

    Gonzalez, Raul S. (et al.)

    Normal or Nearly Normal Liver

    Pages 5-12

    Gonzalez, Raul S. (et al.)

    Portal Inflammation

    Pages 13-25

    Gonzalez, Raul S. (et al.)

    Lobular Changes

    Pages 27-36

    Gonzalez, Raul S. (et al.)

    Biliary and Vascular Changes

    Pages 37-69

    Gonzalez, Raul S. (et al.)

    Cholestasis

    Pages 71-83

    Gonzalez, Raul S. (et al.)Steatosis

    Pages 85-114

    Gonzalez, Raul S. (et al.)

    Fibrosis and Cirrhosis

    Pages 115-122

    Gonzalez, Raul S. (et al.)

    Granulomas

    Pages 123-145

    Gonzalez, Raul S. (et al.)

    Sinusoidal Changes

    Pages 147-167

    Gonzalez, Raul S. (et al.)

    Necrosis

    Pages 169-180

    Gonzalez, Raul S. (et al.)

    Pigments and Inclusions

    Pages 181-201

    Gonzalez, Raul S. (et al.)

    Funny-Looking Cells

    Pages 203-210

    Gonzalez, Raul S. (et al.)

    Liver Transplantation

    Pages 211-231

    Gonzalez, Raul S. (et al.)

    Pediatric Liver Disease

    Pages 233-272

    Gonzalez, Raul S. (et al.)

    Special and Immunohistochemical Stains

    Pages 273-280

    Gonzalez, Raul S. (et al.)

     

  • 70000lei 570.00 lei

     

    Diagnose oral diseases quickly and accurately! Oral Pathology: Clinical Pathologic Correlations, 7th Edition presents diseases and conditions by appearance and presentation, so that you can easily identify and plan treatment for common oral and paraoral problems. An atlas-style overview of pathologic conditions opens the book, and then each chapter describes pathologies in detail - depicting each with full-color clinical photos and photomicrographs. In addition to covering the latest advances in oral pathology, this edition includes new radiographic images demonstrating advanced imaging techniques. Expert educators Joseph Regezi, James Sciubba, and Richard Jordan provide a quick reference that's ideal for the lab, NBDE review, or chairside use!

    ·         Organization of oral and maxillofacial diseases by clinical appearance - such as red-blue lesions or pigmented lesions - matches what you would expect to see upon a patient's presentation, and provides a practical tool for developing differential diagnoses and planning treatment.

    ·         Nearly 1,000 full-color clinical photographs, photomicrographs, radiographs, and drawings help you learn to identify lesions and disease states.

    ·         An atlas-style Clinical Overview section makes it easy to find key information, with one page showing clinical photos of common conditions and the facing page listing symptoms, causes, and significance.

    ·         Nearly 200 summary boxes and tables offer clear, at-a-glance information on the clinical features, diagnosis, and treatment for many conditions.

    ·         Correlation of histopathology with clinical features of oral diseases assists the clinician in recognizing specific conditions and developing differential diagnoses and rational treatment approaches.

    ·         Student resources on an Evolve companion website include 30 case studies, interactive lecture modules, and a 150-question practice exam to prepare you for the NBDE and for clinical practice.

    UPDATED content reflects current information and the latest advances in oral and maxillofacial pathology.

     

  • Fundamentals of Renal Pathology
    La comanda in aproximativ 4 saptamani
    67400lei 580.00 lei

    Fundamentals of Renal Pathology is a compact and up-to-date resource on the basics of renal pathology that will be of particular value for residents and fellows in training in renal pathology, general pathology, and nephrology, but will also serve as a handy reference for the more experienced. This second, revised and updated edition of the book offers an integrated approach based on contributions from established experts in the field. Key diseases are discussed within the context of clinical presentations, with the emphasis on clinicopathological correlation and differential diagnosis. Topics discussed include glomerular diseases with nephrotic or nephritic syndrome presentations; systemic and vascular diseases affecting the kidney, including diseases affecting the renal transplant; tubulointerstitial diseases; and plasma cell dyscrasias and associated diseases. Well-chosen color illustrations and electron micrographs enhance and complement the text.

  • 620.00 lei

    This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2.

    Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.

  • 68200lei 620.00 lei

     

    Description:

     

    This book provides a comprehensive and up-to-date overview of the pathologic features of common benign and malignant hematopoietic disorders in spleen and liver for practicing pathologists, hematopathologists and clinicians. The authors are from large academic centers, affiliated teaching hospitals and central referral clinics and are experienced in the diagnosis of hematopoietic disorders in the spleen and liver. The book consists of 21 chapters, with the first three chapters devoted to normal histologic features, conventional, cytogenetic and molecular studies necessary for the diagnosis of hematopoietic disorders in the spleen and liver. Chapters 4 to 17 cover the primary and secondary mature B- and T/NK cell lymphomas, Hodgkin lymphoma, B and T cell lymphoblastic leukemias, myeloid neoplasms, histiocytic and dendritic neoplasms, and post-transplant disorders including post transplant lymphoproliferative disorders. Chapters 19 to 21 encompass red blood cell disorders, other benign hematologic disorders and infectious/inflammatory disorders that could mimic hematopoietic neoplasms. These chapters are formatted on specific hematopoietic neoplasms to comprise epidemiology, etiology, pathogenesis, morphology, immunophenotyping, molecular genetics, prognosis and brief treatment guidelines. Diagnostic caveats are included in order to have a quick review of the key points in each chapter. Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver covers most, if not all of the benign and malignant hematopoietic disorders in the spleen and liver and serves as a practical and useful resource for general pathologists and hematopathologists.

     

    Table of Contents:

     

    1. Anatomy and Histology of Normal Liver and Spleen

    2. Diagnostic Approaches to Hematopoietic Disorders of the Spleen and Liver

    3. Molecular and Genetic Diagnostic Approaches of Hematopoietic Disorders of the Spleen and Liver

    4. Hairy Cell Leukemia, Hairy Cell Leukemia Variant, and Splenic Diffuse Red Pulp Small B-Cell Lymphoma

    5. Splenic Marginal Zone Lymphoma and Other Small B-Cell Lymphomas

    6. Large B-Cell Lymphomas of the Spleen

    7. Primary Hepatic B-Cell Lymphomas

    8. Plasma Cell Neoplasms and Amyloidosis in the Liver and Spleen

    9. Hepatosplenic T-Cell Lymphoma

    10. T-Cell Large Granular Lymphocytic Leukemia Involving the Liver and Spleen

    11. Uncommon Mature T-Cell Lymphomas

    12. Hodgkin Lymphoma in the Liver and Spleen

    13. B-Lymphoblastic Leukemia/Lymphoma Involving the Spleen or Liver

    14. T-Lymphoblastic Leukemia/Lymphoma Involving the Spleen or Liver

    15. Aggressive Natural Killer-Cell Leukemia and T-Cell Prolymphocytic Leukemia: Two Rare and Highly Aggressive Hematologic Neoplasms Typically Involving the Liver and Spleen

    16. Myeloid Neoplasms in the Liver and Spleen

    17. Histiocytic and Dendritic Cell Disorders in the Liver and Spleen

    18. Transplant-Related Disorders in the Liver and Spleen

    19. Benign Red Blood Cell Disorders in the Liver and Spleen

    20. Benign Hematologic Disorders Involving the Liver and Spleen

    21. Infectious and Inflammatory Mimickers of Hematopoietic Disorders in the Liver and Spleen

     

  • 640.00 lei

    This practical book covers all aspects of diseases of bones and joints in one easily readable volume. Richly illustrated in color with abundant photographs and diagrams, each disease category includes a short introduction, discussion of clinical, radiographic and pathologic features, and treatment suggestions. Fully updated throughout, this new edition discusses the molecular genetics of orthopedic diseases and new imaging modalities such as the PET scan. Newly clarified entities are included, such as failure of metal-on-metal hip prostheses, osteonecrosis of the jaw, atypical femoral fractures, and rapidly destructive hip arthrosis. Drawing on their extensive experience as clinicians and teachers, the authors' accessible narrative style enables easy comprehension. Written by a bone pathologist and an orthopedic surgeon, the book emphasizes a team approach to diagnosis and treatment. This is an essential resource for residents in pathology, orthopedic surgery and radiology, and also serves as a valuable handbook for senior practitioners in these specialties. The book is packaged with a password, giving the user online access to all the text and images.

  • 73000lei 640.00 lei

    This book offers a comprehensive yet concise overview of immunoprofile of tumors and antibodies used in contemporary surgical pathology, and provides diagnostic algorithms for approaching tumor diagnostics.

    Immunohistochemistry has become the most important ancillary technique in diagnostic pathology in the last 20 years, and unlike most books on tumor diagnostics, this volume discusses in details immunohistochemical biomarkers, diagnostic approaches and their pitfalls, as well as the immunoprofile of common tumors throughout all systems of human body. With numerous color figures and detailed flowcharts, it appeals to all pathologists be they young residents in training who want a brief introduction to this technique, or specialists in need of a reliable and comprehensive reference resource in tumors diagnostics.

  • Biopsy Interpretation of the Prostate
    La comanda in aproximativ 4 saptamani
    79800lei 645.00 lei

    Part of the highly regarded Biopsy Interpretation Series, this fully revised volume is your definitive guide to mastering biopsy pathology interpretation for prostate cancer care. Biopsy Interpretation of the Prostate, 6th Edition, provides superbly illustrated guidance from a top expert in the field, guiding you through the best utilization of H&E microscopy as well as the latest immunohistochemical markers in order to deliver accurate, reliable diagnoses. Hundreds of full-color illustrations depict the full range of benign and malignant prostatic entities.

    • Focuses on practical, need-to-know information regarding the diagnosis and prognosis of prostate cancer obtained on biopsy, addressing both common and unusual issues that arise in day-to-day practice.
    • Provides new information on noninvasive lesions (HGPIN and intraductal carcinoma), clinical correlates with biopsy, and practical molecular findings.
    • Shows how to critically use adjunctive tests to both diagnose limited prostate cancer and avoid overdiagnosing mimickers of prostate cancer.
    • Emphasizes the newest updates in prostate cancer grading so that you can provide the most accurate prognostication in your biopsy reports.
    • Features 1800 images online, as well as a 50-question test bank for self-assessment and review.

    ·  1 Clinical Correlates with Biopsy: Serum Prostate-Specific Antigen, Digital Rectal Examination, and Imaging Techniques

    ·  DIGITAL RECTAL EXAMINATION

    ·  IMAGING TECHNIQUES

    ·  PROSTATE-SPECIFIC ANTIGEN

    ·  Total Serum Prostate-Specific Antigen

    ·  Prostate-Specific Antigen Density

    ·  Age-Specific Prostate-Specific Antigen Reference Ranges

    ·  Prostate-Specific Antigen Velocity (Rate of Change of Prostate-Specific Antigen)

    ·  Molecular Forms of Prostate-Specific Antigen

    ·  Other Prostate Serum and Urine Markers

    ·  Prostate-Specific Antigen Factored into TNM Staging

    ·  Prostate-Specific Antigen Relation to Post-therapy Follow-up Biopsies

    ·  2 Needle Biopsy Technique, Tissue Sampling, and Processing of Needle Biopsy and Transurethral Resection Specimens

    ·  NEEDLE BIOPSY TECHNIQUE

    ·  NEEDLE BIOPSY PROCESSING—FIXATIVE

    ·  NEEDLE BIOPSY PROCESSING—NUMBER OF LEVELS

    ·  NEEDLE BIOPSY PROCESSING—INTERVENING UNSTAINED SLIDES

    ·  NEEDLE BIOPSY PROCESSING—NUMBER OF TISSUE CORES PER BLOCK/SLIDE

    ·  NEEDLE BIOPSY—INKING THE PERIPHERAL END OF THE CORE

    ·  SAMPLING OF TRANSURETHRAL RESECTION SPECIMENS

    ·  3 Gross Anatomy and Normal Histology

    ·  GROSS ANATOMY

    ·  HISTOLOGY

    ·  BENIGN PROSTATIC HYPERTROPHY

    ·  4 Inflammatory Conditions

    ·  ACUTE AND CHRONIC PROSTATIC INFLAMMATION

    ·  MALAKOPLAKIA

    ·  SARCOIDOSIS

    ·  GRANULOMATOUS PROSTATITIS

    ·  MYCOTIC PROSTATITIS

    ·  MYCOBACTERIAL PROSTATITIS

    ·  NONSPECIFIC GRANULOMATOUS PROSTATITIS

    ·  POSTBIOPSY GRANULOMAS

    ·  SYSTEMIC GRANULOMATOUS PROSTATITIS

    ·  MISCELLANEOUS INFECTIONS

    ·  5 Noninvasive Lesions in the Prostate: Prostatic Intraepithelial Neoplasia and Intraductal Carcinoma of the Prostate

    ·  PROSTATIC INTRAEPITHELIAL NEOPLASIA

    ·  Evidence Linking Prostatic Intraepithelial Neoplasia to Cancer

    ·  Mimickers of Prostatic Intraepithelial Neoplasia

    ·  Low-Grade Prostatic Intraepithelial Neoplasia: Risk of Cancer on Rebiopsy

    ·  High-Grade Prostatic Intraepithelial Neoplasia: Incidence on Biopsy

    ·  High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Overall Risk of Cancer

    ·  High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Risk of Cancer Stratified by Clinical Predictors

    ·  High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Risk of Cancer Stratified by Pathologic Predictors

    ·  High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Repeat Biopsy Strategy and Technique

    ·  High-Grade Prostatic Intraepithelial Neoplasia: Significance on Transurethral Resection of the Prostate Material

    ·  High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Findings at Subsequent Radical Prostatectomy

    ·  INTRADUCTAL CARCINOMA OF THE PROSTATE

    ·  Incidence of Intraductal Carcinoma of the Prostate

    ·  Differential Diagnosis of Intraductal Carcinoma of the Prostate

    ·  Significance of Intraductal Carcinoma of the Prostate on Biopsy

    ·  6 Diagnosis of Limited Adenocarcinoma of the Prostate

    ·  DIAGNOSIS ON NEEDLE BIOPSY

    ·  General Principles in Diagnosing Prostate Cancer

    ·  ARCHITECTURAL FEATURES IN THE DIAGNOSIS OF CANCER

    ·  NUCLEAR FEATURES IN THE DIAGNOSIS OF CANCER

    ·  CYTOPLASMIC FEATURES IN THE DIAGNOSIS OF CANCER

    ·  INTRALUMINAL CONTENTS IN THE DIAGNOSIS OF CANCER

    ·  STROMAL CHANGES

    ·  HISTOLOGIC FEATURES SPECIFIC FOR PROSTATE CANCER

    ·  IDENTIFICATION OF BASAL CELLS ON H&E-STAINED SECTIONS

    ·  DIAGNOSIS OF LIMITED HIGH-GRADE CARCINOMA

    ·  CARCINOMAS MIMICKING BENIGN GLANDS

    ·  DIAGNOSIS OF CANCER ON TRANSURETHRAL RESECTION

    ·  USE OF IMMUNOHISTOCHEMICAL ADJUNCTIVE TESTS FOR DIAGNOSIS OF CARCINOMA

    ·  7 Mimickers of Prostate Adenocarcinoma

    ·  MIMICKERS OF GLEASON PATTERN 3 ADENOCARCINOMA

    ·  Adenosis

    ·  Diffuse Adenosis of the Peripheral Zone

    ·  Atrophy

    ·  Basal Cell Hyperplasia

    ·  Colonic Mucosa

    ·  Cowper Glands

    ·  Mesonephric Hyperplasia

    ·  Nephrogenic Adenoma

    ·  Radiation Atypia

    ·  Seminal Vesicles

    ·  Verumontanum Mucosal Gland Hyperplasia

    ·  MIMICKERS OF GLEASON PATTERNS 4 AND 5 ADENOCARCINOMA

    ·  Clear Cell Cribriform Hyperplasia

    ·  Nonspecific Granulomatous Prostatitis

    ·  Paraganglia

    ·  Sclerosing Adenosis

    ·  Signet Ring Lymphocytes

    ·  Xanthoma

    ·  8 Reporting Cancer: Influence on Prognosis and Treatment

    ·  NEEDLE BIOPSY

    ·  Use of Macros (Canned Text)

    ·  Quantification of Amount of Cancer on Needle Biopsy

    ·  LOCATION OF POSITIVE BIOPSY CORES

    ·  PERINEURAL INVASION

    ·  LYMPHOVASCULAR INVASION

    ·  USE OF NOMOGRAMS

    ·  DIRECT STAGING ON NEEDLE BIOPSY

    ·  TRANSURETHRAL RESECTION

    ·  Subclassification

    ·  9 Grading of Prostatic Adenocarcinomas

    ·  HISTORICAL BACKGROUND

    ·  INTERNATIONAL SOCIETY OF UROLOGICAL PATHOLOGY MODIFICATIONS TO GLEASON GRADING

    ·  2005 International Society of Urological Pathology Consensus Conference

    ·  2014 International Society of Urological Pathology Consensus Conference

    ·  GENERAL APPLICATIONS OF THE GLEASON GRADING SYSTEM

    ·  GLEASON PATTERNS

    ·  Historical Gleason Patterns 1 and 2

    ·  Gleason Pattern 3

    ·  Gleason Pattern 4

    ·  Gleason Pattern 5

    ·  GRADING VARIANTS OF PROSTATE CARCINOMA

    ·  Adenocarcinoma with Vacuoles

    ·  Foamy Gland Carcinoma

    ·  Pseudohyperplastic Adenocarcinoma

    ·  REPORTING GLEASON GRADE ON BIOPSY

    ·  Different Cores with Different Grades

    ·  Tertiary Gleason Patterns

    ·  Reporting Secondary Patterns of Higher Grade When Present to a Limited Extent

    ·  Reporting Secondary Patterns of Lower Grade When Present to a Limited Extent

    ·  Reporting Percentage Pattern 4 on Needle Biopsies

    ·  CORRELATION NEEDLE BIOPSY AND RADICAL PROSTATECTOMY GRADE

    ·  Explanations for Grading Discrepancies

    ·  Factors Associated with Increased Upgrading and Downgrading from Biopsy to Prostatectomy

    ·  INTEROBSERVER REPRODUCIBILITY

    ·  GLEASON GRADE GROUPING

    ·  CHANGE OF GRADE OVER TIME

    ·  USE OF ARTIFICIAL INTELLIGENCE FOR GRADING

    ·  10 Findings of Atypical Glands Suspicious for Cancer

    ·  INCIDENCE OF ATYPICAL DIAGNOSIS ON NEEDLE BIOPSY

    ·  INTEROBSERVER REPRODUCIBILITY

    ·  PROSTATE CANCER RISK FOLLOWING A DIAGNOSIS OF ATYPIA

    ·  RADICAL PROSTATECTOMY AFTER CANCER DIAGNOSED POSTATYPICAL BIOPSY

    ·  REBIOPSY TECHNIQUES FOLLOWING A DIAGNOSIS OF ATYPIA

    ·  HISTOLOGY–ATYPICAL SMALL GLANDS

    ·  11 Prostatic Duct Adenocarcinoma

    ·  12 Neuroendocrine Differentiation in the Benign and Malignant Prostate

    ·  NEUROENDOCRINE CELLS IN NORMAL PROSTATE HISTOLOGY

    ·  NEUROENDOCRINE CELLS AND DIFFERENTIATION IN PROSTATE CANCER

    ·  USUAL PROSTATE ADENOCARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION

    ·  ADENOCARCINOMA WITH PANETH CELL-LIKE NEUROENDOCRINE DIFFERENTIATION

    ·  CARCINOID TUMOR

    ·  SMALL CELL CARCINOMA

    ·  LARGE CELL NEUROENDOCRINE CARCINOMA

    ·  MIXED NEUROENDOCRINE CARCINOMA–ACINAR ADENOCARCINOMA

    ·  PROSTATE CARCINOMA WITH OVERLAPPING FEATURES OF SMALL CELL AND ACINAR ADENOCARCINOMA

    ·  CASTRATE-RESISTANT PROSTATE CANCER WITH SMALL CELL CARCINOMA–LIKE CLINICAL PRESENTATION

    ·  13 Mucinous Differentiation in the Benign and Malignant Prostate

    ·  MUCINOUS ADENOCARCINOMA OF THE PROSTATE

    ·  PROSTATIC URETHRAL ADENOCARCINOMA

    ·  14 Benign and Malignant Prostate following Treatment

    ·  ANTIANDROGEN THERAPY

    ·  RADIATION

    ·  POSTRADICAL PROSTATECTOMY BIOPSIES

    ·  EMERGING FOCAL/ABLATIVE THERAPIES

    ·  Cryotherapy

    ·  High-Intensity Frequency Ultrasound

    ·  Vascular-Targeted Photodynamic Therapy

    ·  HYPERTHERMIA

    ·  PHYTOTHERAPY

    ·  POST-TEFLON INJECTION GRANULOMAS

    ·  POSTNEEDLE BIOPSY CHANGES

    ·  15 Urothelial Carcinoma

    ·  DISTINCTION OF HIGH-GRADE PROSTATIC ADENOCARCINOMA FROM UROTHELIAL CARCINOMA

    ·  PROSTATIC INTRADUCTAL UROTHELIAL CARCINOMA WITH OR WITHOUT PROSTATIC STROMAL INVASION

    ·  UROTHELIAL CARCINOMA SEEN ON NEEDLE BIOPSY

    ·  PRIMARY UROTHELIAL CARCINOMA

    ·  16 Mesenchymal Tumors and Tumor-like Conditions

    ·  STROMAL TUMORS OF UNCERTAIN MALIGNANT POTENTIAL AND STROMAL SARCOMAS

    ·  LEIOMYOMA/LEIOMYOSARCOMA

    ·  INFLAMMATORY MYOFIBROBLASTIC TUMOR

    ·  SOLITARY FIBROUS TUMOR

    ·  GASTROINTESTINAL STROMAL TUMOR

    ·  RHABDOMYOSARCOMA

    ·  MISCELLANEOUS

    ·  17 Miscellaneous Benign and Malignant Lesions

    ·  BENIGN LESIONS

    ·  Prostatic Cysts

    ·  Multilocular Cysts of the Prostate (Multilocular Prostatic Cystadenoma)

    ·  Melanotic Lesions

    ·  Amyloid

    ·  Calculi and Calcification

    ·  Infarcts

    ·  Miscellaneous

    ·  MALIGNANT LESIONS

    ·  Basal Cell Carcinomas

    ·  Carcinomas with Squamous Differentiation

    ·  Sarcomatoid Carcinoma

    ·  Hematopoietic Tumors

    ·  Miscellaneous Primary Tumors

    ·  Involvement of the Prostate by Secondary Tumors

    ·  18 Prostatic Urethral Lesions

    ·  PROSTATIC URETHRAL POLYPS

    ·  MISCELLANEOUS URETHRAL POLYPS

    ·  NEPHROGENIC ADENOMAS

    ·  INVERTED PAPILLOMA OF THE PROSTATIC URETHRA

    ·  MISCELLANEOUS

    ·  19 Tissue-based Biomarkers Using Needle Biopsy Material

    ·  COMMERCIAL GENOMIC ASSAYS

    ·  PTEN LOSS

    ·  Germ Line Testing for DNA Damage Repair Genes

    ·  HOXB13

    ·  MOLECULAR SPECIMEN IDENTITY TESTING

     


  • 73500lei 660.00 lei

     

    Description:

     

    The liver is a complex organ due to its unique microscopic structure, intricate metabolic functions and susceptibility to a wide variety of insults, manifesting in countless histological  patterns.  Atlas of Liver Pathology considers both changes seen in medical liver biopsies as well as lesional biopsies when the specimen has been taken from a mass. The book starts by reviewing normal structure and its variants and the optimal approaches for the preparation of histological sections for diagnostic liver pathology. The following chapters are dedicated to developmental, metabolic, infectious, drug related, autoimmune, biliary, vascular and neoplastic disorders. Two sections on liver pathology in pregnancy and transplantation conclude the work. Macroscopic illustrations are included where appropriate. All photographs are complemented by legends describing the picture and providing relevant related information.

    Authored by nationally and internationally recognized pathologists, Atlas of Liver Pathology is a valuable resource that serves as a quick reference guide for the diagnosis of usual and unusual diseases.

     

    Table of contents (17 chapters):

     

    Normal, Variants, and Methods

    Pages 1-17

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    General Processes

    Pages 19-37

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Developmental Abnormalities

    Pages 39-48

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Metabolic Liver Disease

    Pages 49-70

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Fatty Liver Disease

    Pages 71-84

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Viral Liver Disease

    Pages 85-103

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Nonviral Infectious Liver Disease

    Pages 105-117

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Drug-Induced Liver Injury

    Pages 119-137

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Autoimmune Hepatitis

    Pages 139-148

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Biliary Disease

    Pages 149-162

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Vascular Disorders

    Pages 163-170

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Premalignant Lesions

    Pages 171-177

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Neoplasm-like Liver Lesions

    Pages 179-183

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

    Epithelial Liver Neoplasms

    Pages 185-207

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Nonepithelial Liver Neoplasms

    Pages 209-219

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Obstetric Liver Disease

    Pages 221-224

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

    Transplantation Pathology

    Pages 225-239

    Chan, Anthony W. H., BMedSc, MBChB, FRCPA, FHKCPath, FHKAM (Pathology) (et al.)

     

     

  • 78500lei 670.00 lei

    Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies.

  • 72700lei 670.00 lei

    Systematically solve tough diagnostic challenges in GI pathology with Differential Diagnoses in Surgical Pathology: Gastrointestinal Tract! This clinical reference in the Differential Diagnoses in Surgical Pathology Series uses select images of clinical and pathological findings together with succinct, expert instructions, to guide you through the decision-making process by distinguishing between commonly confused Gastrointestinal lesions. 

    Key Features
    • Efficiently work through more than 150 differential diagnoses in GI pathology presented side-by-side for easy comparison, including the most common entities as well as selected rarer diseases.
    • Get all the assistance you need at a glance with concise, bulleted summaries of clinical and pathological findings and view relevant pictorial examples on the corresponding pages.
    • View high-quality images of similar-looking lesions side by side for easy comparison
    Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to:
    • Complete content with enhanced navigation
    • A powerful search that pulls results from content in the book, your notes, and even the web
    • Cross-linked pages, references, and more for easy navigation
    • A Highlighting tool for easier reference of key content throughout the text
    • The ability to take and share notes with friends and colleagues
    • Quick reference tabbing to save your favorite content for future use

  • 82500lei 670.00 lei

    Systematically solve tough diagnostic challenges in head and neck pathology with this new title in the Differential Diagnoses in Surgical Pathology series.  This practical, full-color reference uses select images of clinical and pathological findings, together with succinct, expert instructions, to guide you through the decision-making process by distinguishing between commonly confused lesions of the head and neck.  By presenting material according to the way pathologists actually work, this user-friendly volume helps you quickly differentiate entities that have overlapping morphologic features.

    Key Features: 

    • Presents over 200 differential diagnoses in head and neck pathology side by side for easy comparison, including the most common entities as well as selected rarer diseases.
    • Provides concise, bulleted summaries of clinical and pathological findings and relevant pictorial examples on the corresponding pages.
    • Features nearly 1,000 high-quality images of similar-looking lesions side by side for easy comparison.
    • Includes cases on the salivary glands, odontogenic/bone, ear, neck/soft tissue, oral cavity, oropharynx, larynx, sinonasal tract/nasopharynx, and thyroid and parathyroid glands.
    • Ideal for practicing pathologists, pathologists in training, residents, and medical students.

    Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:

    • Complete content with enhanced navigation
    • Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
    • Cross-linked pages, references, and more for easy navigation
    • Highlighting tool for easier reference of key content throughout the text
    • Ability to take and share notes with friends and colleagues
    • Quick reference tabbing to save your favorite content for future use

  • Scheuer's Liver Biopsy Interpretation
    La comanda in aproximativ 4 saptamani
    80000lei 680.00 lei

    Description:

    Trusted for more than 50 years by pathologists in practice and in training, Scheuer’s Liver Biopsy Interpretation is a well-organized, superbly illustrated guide designed to help solve diagnostic problems at the microscope. Authored by renowned expert Dr. Jay Lefkowitch and reflecting the extensive experience of the late Dr. Peter Scheuer, this practical text contains technical tips, diagnostic clues, and pearls on all aspects of liver pathology diagnosis, including acute and chronic hepatitis, biliary tract diseases, childhood disorders, and hepatic neoplasms - as well as ancillary topics such as biopsy assessment, laboratory techniques, normal liver histology, and transplantation. Throughout the text, histopathologic features are correlated with clinical features, molecular genetics, and immunohistochemistry to provide a practical account of how pathology impacts the diagnosis and management of liver disease.

    Key Features:

    Covers key topics such as genomic alterations in liver tumours, diagnosis of acute liver allograft rejection, scoring systems for non-alcoholic fatty liver disease, and discussions of immunohistochemical features wherever relevant.

    Presents the latest information on next generation sequencing and drug-induced liver injury, including adverse reactions to new biologics and alternative medicines to help both the clinician and pathologist avoid diagnostic errors.

    Features many new illustrations, including over 300 large, full-color and fully annotated photomicrographs that illustrate a wide range of pathologic appearances and help identify each diagnostic entity under discussion.

    Offers coverage of cytopathology in the assessment of liver tumors to provide further clinical clues to diagnosis.

    Provides basic overview of major histopathologic diagnostic problems in paediatric liver biopsy, including biliary atresia and several types of progressive familial intrahepatic cholestasis

    Provides new and updated algorithms, tables and images highlighting key features of each diagnostic entity - ideal as a concise review during sign out or for studying and board preparation.

    Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

     

    Table of Contents:

    1. General Principles of Biopsy Assessment
    2. Laboratory Techniques
    3. The Normal Liver
    4. Assessment and Differential Diagnosis of Pathological Features
    5. Biliary Disease
    6. Acute Viral Hepatitis
    7. Steatosis, Steatohepatitis and Related Conditions
    8. Drugs and Toxins
    9. Chronic Hepatitis
    10. Cirrhosis
    11. Neoplasms and Nodules
    12. Vascular Disorders
    13. Childhood Liver Disease and Metabolic Disorders
    14. Disturbances of Copper and Iron Metabolism
    15. The Liver in Systemic Disease and Pregnancy
    16. The Liver in Organ Transplantation
    17. Electron Microscopy and Other Techniques
     

     


  • 76200lei 690.00 lei

    This practical resource, a volume in the new Differential Diagnoses in Surgical Pathology series, is arranged by differential diagnoses, filling a niche in urologic pathology resources and providing a practical guide to making the correct diagnosis between commonly confused entities.
     
    This innovative book covers over 175 differential diagnoses, ranging from the most common in surgical urologic pathology to select disorders that are less frequently seen. In every chapter, lesions are presented side by side for easy comparison, with clinical and pathological findings in short outline format followed by several full color images.  In addition to illustrating and discussing the classical features of these entities, the authors emphasize atypical features that can complicate diagnoses.
     
    Key Features
    • Side-by-side comparisons for each major differential diagnoses for quick and accurate reference
    • Over 1,450 color photographs that depict the features of each entity  and cover all major differential diagnoses in genitourinary pathology
    • A practical guide that directs all text and photographs toward differentiating between entities to ensure the pathologist arrives at an accurate diagnosis
    • A companion website with fully-searchable text and an image bank

  • 78000lei 710.00 lei

    Biopsy Interpretation of the Kidney and Adrenal Gland


    This practical volume in the Biopsy Interpretation Series is your guide to effective diagnostic biopsy of the kidney and adrenal glands. Presented in a reader-friendly format, the text includes abundant photomicrographs of actual biopsy samples as well as correlative photos of surgical specimens and ancillary immunohistochemical studies.

     

    Each organ is addressed in a separate section that includes an introduction to biopsy techniques and an overview of normal histology. Positive diagnoses for renal lesions are described by tumor type. Adrenal lesions are grouped by primary and metastatic tumors, reflecting the main diagnostic considerations at the adrenal site. Uniquely detailed focus addresses the specific techniques and interpretive features of renal and adrenal biopsy. Timely content addresses the use of renal biopsy in minimally invasive therapeutic techniques as well as its role in active surveillance of renal masses. The latest ISUP classifications reflect newly described renal tumors discussed at the March 2012 USCAP annual meeting. Clinical implications of each diagnosis are highlighted throughout the text to guide therapeutic decision-making.

     

    Look inside and explore…

    • Uniquely detailed focus addresses the specific techniques and interpretive features of renal and adrenal biopsy.
    • Timely content addresses the use of renal biopsy in minimally invasive therapeutic techniques as well as its role in active surveillance of renal masses.

    • The latest ISUP classifications reflect newly described renal tumors discussed at the March 2012 USCAP annual meeting.

    • Clinical implications of each diagnosis are highlighted throughout the text to guide therapeutic decision-making.

  • 80900lei 720.00 lei

    Description:

    Part of the new Pattern-Based Approach series, designed to teach pathology in a way that reflects actual sign-out, this new visually-oriented guidebook presents real-life cases and practical diagnostic tips. Disease processes are organized into ‘patterns’ of injury—the method by which pathologists approach their work—and self-assessment quizzes are provided for each chapter to give you experience with high-yield, board-style teaching topics.

     

    Table of Contents:

     

    1 BASIC PATTERNS IN LIVER PATHOLOGY

    Introduction

    Acute Hepatitis Versus Chronic Hepatitis Versus Acute-on-Chronic Hepatitis

    Acute Liver Failure

    Almost-Normal Liver

    Resolving Hepatitis Pattern

    Cytoplasmic Changes

    Bland Lobular Necrosis

    Fatty Liver

    Hepatitic Pattern of Injury

    Giant Cell Hepatitis

    Granulomas

    Bland Lobular Cholestasis

    Biliary Obstruction

    Ductopenia

    Chronic Biliary/Cholestatic Injury

    Vascular Disease

    Combined Patterns

    Cryptogenic Cirrhosis

    Hepatocellular Tumors

    Near Misses

    2 ACUTE AND CHRONIC VIRAL HEPATITIS

    General Considerations

    Determining Etiology

    Acute Versus Chronic Hepatitis

    Grading Hepatitis

    Staging Hepatitis

    Specific Hepatotropic Viruses

    General Histology Patterns

    Hepatitis A

    Hepatitis B

    Hepatitis D Infection

    Hepatitis C

    Fibrosing Cholestatic Hepatitis B And C

    Hepatitis E Viral Infection

    Nonhepatotropic Viruses

    Epstein–Barr Virus (EBV)

    Cytomegalovirus (CMV)

    Adenovirus, Herpes Simplex Virus (HSV), and Varicella Zoster Virus (VZV)

    Near Misses

    3 NONVIRAL INFECTIONS OF THE LIVER

    Introduction

    Parasitic Infections

    Echinococcosis

    Schistosomiasis

    Tick-Borne Diseases

    Bacterial Infections

    Syphilis

    Whipple Disease

    Actinomycosis

    Liver Abscesses

    Malaria

    Near Misses

    4 GRANULOMAS AND GRANULOMATOUS DISEASE

    Overview

    Approach to Diagnosis

    Types of Granulomas

    Fibrin Ring Granuloma

    Fibrotic Granuloma

    Foreign Body Granuloma

    Lipogranuloma

    Mineral Oil Granuloma

    Necrotizing Granuloma

    Specific Granulomatous Diseases

    Mycobacterium Tuberculosis

    Bacillus Calmette–Guerin and Other Mycobacterium Infections

    Mycobacterium Leprae

    Fungal Infections

    Parasites

    Sarcoidosis

    Common Variable Immunodeficiency (CVID)

    Crohn Disease

    Drug Reactions

    Granulomas and Neoplasms

    Other Causes

    Near Misses

    5 DRUG-INDUCED LIVER INJURY

    Overview

    General Approach

    Inflammatory Patterns of Injury

    Idiosyncratic Drug Reactions

    Resolving Pattern of Hepatitis

    Direct Toxins

    Allergic Type Drug Reactions

    Other Patterns of Injury

    Isolated Hyperammonemia

    Hypervitaminosis A

    Glycogen Pseudo–Ground Glass Changes

    Other Drug-Induced Smooth Endoplasmic Reticulum Proliferations

    Glycogenic Hepatopathy

    Macrovesicular Steatosis

    Microvesicular Steatosis

    Phospholipidiosis

    Ductopenic Pattern

    Vascular Changes Associated with Dili

    Medications Associated with Fibrosis

    Near Misses

    6 FATTY LIVER DISEASE

    Introduction

    Nonalcohol Fatty Liver Disease (NAFLD)

    All About the Fat

    How Do You Go from Steatosis to Steatohepatitis?

    Balloon Cells

    Lobular Inflammation

    Portal Inflammation

    Other Findings in Fatty Liver Disease

    Formal Grading and Staging

    Determining Etiology

    Alcohol Liver Disease

    Drug Reactions Causing Fatty Liver Disease

    Other Rare Causes of Macrovesicular Steatosis

    Microvesicular Steatosis

    Near Misses

    7 AUTOIMMUNE HEPATITIS

    Clinical Findings

    Laboratory Findings

    Histological Findings

    Overview of Histological Findings

    Interface Activity

    Portal Tract Inflammation

    Lobular Changes

    Fulminant Liver Failure

    Cryptogenic Cirrhosis and “Burned Out Autoimmune Hepatitis”

    Autoimmune Hepatitis in Men

    Immunohistochemical Findings

    Fibrosis Staging

    Pediatric Autoimmune Hepatitis

    Overlap Syndromes

    Aih–Pbc: Overlap Between Autoimmune Hepatitis and Primary Biliary Cirrhosis

    Aih–Psc: Overlap Between Autoimmune Hepatitis and Primary Sclerosing Cholangitis

    Near Misses

    8 CHOLESTATIC AND BILIARY TRACT DISEASE

    Introduction

    Bland Lobular Cholestasis Pattern

    Biliary Cirrhosis Pattern

    Biliary Obstruction Pattern

    Special Stains

    Diseases that can Mimic Biliary Obstruction

    Ascending Cholangitis

    Primary Sclerosing Cholangitis

    Small Duct Primary Sclerosing Cholangitis

    Primary Biliary Cirrhosis

    A New Name?

    Clinical and Laboratory Findings

    Histology Findings

    Idiopathic Ductopenia

    Igg4 Sclerosing Disease

    Igg4 Immunohistochemistry

    Sclerosing Cholangitis Associated with Type 2 Autoimmune Pancreatitis

    Segmental Cholangiectasia

    Pediatric Cholestatic Liver Disease

    Overview

    Biliary Atresia

    Neonatal Giant Cell Hepatitis

    Paucity of Intrahepatic Bile Ducts

    Bile Salt Deficiency Diseases

    Serum Findings

    Histological Findings

    Inherited Defects in Bilirubin Metabolism

    Cystic Biliary Diseases and Bile Duct  Malformations

    Congenital Hepatic Fibrosis/Autosomal Recessive Polycystic Kidney And Liver Disease

    Caroli Syndrome/Caroli Disease

    Autosomal Dominant Polycystic Kidney and Liver Disease

    Solitary Bile Duct Cysts

    Near Misses

    9 VASCULAR DISEASE

    General Histologial Patterns

    Patterns of Injury With Portal Vein Disease

    Acute Portal Vein Disease

    Chronic Portal Vein Disease

    Patterns of Injury With Hepatic Artery Disease

    Sinusoidalinusoidal Disease

    Veno-Occlusive Disease

    Sickle Cell Disease

    Vascular Outflow Disease

    Congenital/Genetic Abnormalities

    Hereditary Hemorrhagic Telangiectasia

    Hereditary Lymphedema

    Nodular Regenerative Hyperplasia

    Peliosis Hepatitis

    Segmental Atrophy and Nodular Elastosis

    Tumors Associated With Vascular Disease

    Near Misses

    10 SYSTEMIC DISEASES INVOLVING THE LIVER

    Amyloid

    Lect2 Amyloid

    Light Chain Deposition Disease

    WaldenströM Macroglobulinaemia

    Diabetes Mellitus

    Fatty Liver Disease

    Glycogenic Hepatopathy

    Diabetic Hepatosclerosis

    Other Endocrine Diseases

    Hypopituitary Disease

    Thyroid Disease

    Inflammatory Conditions

    Celiac Disease

    Common Variable Immunodeficiency

    Crohn Disease

    Systemic Autoimmune Disease

    Liver Disease in Pregnancy

    Hyperemesis Gravidarum

    Intrahepatic Cholestasis of Pregnancy

    Preeclampsia, Eclampsia, and Hellp Syndrome

    Acute Fatty Liver of Pregnancy

    Hematopathology-Related Diseases

    Langerhans Histiocytosis

    Rosai Dorfman Disease

    Mast Cell Disease

    Other Systemic Dieases

    Cystic Fibrosis

    Hypertension, Systemic

    Sepsis

    Hemophagocytic Syndrome

    Near Misses

    11 TRANSPLANT PATHOLOGY

    Donor Liver Evaluation

    Preservation Changes

    Acute Cellular Rejection

    Grading Acute Cellular Rejection

    Atypical Patterns of Acute Cellular Rejection

    Idiopathic Posttransplant Hepatitis

    Antibody-Mediated Rejection

    Chronic Rejection

    Vascular Problems

    Hepatic Artery Insufficiency

    Small-For-Size Graft

    Piggyback Grafts and Congestive Hepatopathy

    Other Findings

    Opportunistic Viral Infections

    Recurrent Disease

    Glycogenic Hepatopathy

    Drug Reaction

    Posttransplant Lymhoproliferative Disorder

    Graft Versus Host Disease

    Engraftment Syndrome

    Near Misses

    12 GENETIC DISEASES

    Genetic Diseases of the Liver, Overview

    Alpha-1-Antitrypsin Deficiency

    Afibrinogenemia/Hypofibrinogenemia

    Wilson Disease

    Copper Stains

    Quantitative Copper

    Other Rare Copper Overload Diseases

    Hemochromatosis

    Histological Findings

    Genetic Versus Secondary Causes of Iron Overload

    Acquired/Secondary Iron Overload

    Iron in Donor Liver Biopsies

    Determining Iron Levels in the Liver

    Iron-Grading Systems

    Quantitative Measurement of Hepatic Iron Concentrations

    Liver Biopsies in Individuals With Known Hfe Mutations

    Other Rare Genetic Causes of Hemochromatosis

    Ferroportin Disease and Ferroportin-Associated Hemochromatosis

    Neonatal Hemochromatosis

    African Iron Overload Disease

    Glycogen Storage Diseases

    Urea Cycle Defects

    Mucopolysaccharidosis

    Disorders of Lipid Metabolism

    Inborn Errors of Amino Acid Metabolism

    Prader–Willi Disease

    Erythropoietic Protoporhyria

    Disorders of Mitochondria

    Telomere Shortening Syndrome

    Near Misses

    13 PEDIATRIC BENIGN AND MALIGNANT TUMORS

    Hepatoblastoma

    Histological Types

    Hepatoblastoma Staging

    Hepatoblastoma Versus Hepatocellular Carcinoma

    Calcifying Nested Stromal–Epithelial Tumor

    Infantile Hemangioma

    Vascular Malformation

    Mesenchymal Hamartoma

    Embryonal Sarcoma

    Rhabdoid Tumors

    Rhabdomyosarcoma (Also Called Embryonal Rhabdomyosarcoma)

    Near Misses

    14 HEPATOCELLULAR TUMORS

    Focal Fatty Nodule

    Focal Nodular Hyperplasia

    Hepatic Adenoma

    Hepatic Adenoma–Like Nodules in Cirrhotic Livers

    Histological Findings, Overview

    Atypical Hepatic Adenomas

    Hepatic Adenoma Subtypes

    Special High-Risk Subtypes of Hepatic Adenomas

    Malignant Transformation

    Near Misses

    15 MALIGNANT HEPATOCELLULAR TUMORS AND PRECUSORS

    Macroregenerative Nodule

    Dysplastic Nodule

    Hepatocellular Carcinoma

    How to Make the Diagnosis of Hepatocellular Carcinoma

    Evaluating the Reticulin Stain

    Growth Patterns

    Other Findings

    Angiolymphatic Invasion

    Grading Hepatocellular Carcinoma

    Immunohistochemical Patterns

    Background Liver

    Changes After Chemoembolization Therapy

    Histological Subtypes

    Provisional Subtypes of Hepatocellular Carcinoma

    Near Misses

    16 BILIARY TUMORS

    Benign Biliary Lesions

    Reactive Bile Ductular Proliferations

    Bile Duct Hamartoma

    Bile Duct Adenoma

    Biliary Adenofibroma

    Immunostains

    Risk for Malignant Transformation

    Simple Cysts Including Biliary, Mesothelial, and Foregut

    Mucinous Cystic Neoplasm

    Mucinous Cystic Neoplasm without Ovarian Stroma

    Intraductal Papillary Biliary Neoplasm

    Cholangiocarcinoma

    Grading Cholangiocarcinomas

    Immunostains

    Near Misses

    17 ADULT BENIGN AND MALIGNANT MESENCHYMAL TUMORS

    Segmental Atrophy and Nodular Elastosis

    Inflammatory Pseudotumor

    Hemangioma

    Cavernous Hemangioma

    Capillary Hemangioma

    Anastomosing Hemangioma

    Epitheliod Hemangioendothelioma

    Angiosarcoma

    Angiomyolipoma

    Solitar Fibrous Tumor

    Near Misses

    APPENDIX A

    CHAPTER 1. Multiple Choice Questions

    CHAPTER 2. Multiple Choice Questions

    CHAPTER 3. Multiple Choice Questions

    CHAPTER 4. Multiple Choice Questions

    CHAPTER 5. Multiple Choice Questions

    CHAPTER 6. Multiple Choice Questions

    CHAPTER 7. Multiple Choice Questions

    CHAPTER 8. Multiple Choice Questions

    CHAPTER 9. Multiple Choice Questions

    CHAPTER 10. Multiple Choice Questions

    CHAPTER 11. Multiple Choice Questions

    CHAPTER 12. Multiple Choice Questions

    CHAPTER 13. Multiple Choice Questions

    CHAPTER 14. Multiple Choice Questions

    CHAPTER 15. Multiple Choice Questions

    CHAPTER 16. Multiple Choice Questions

    CHAPTER 17. Multiple Choice Questions

     

  • 84000lei 720.00 lei

     

    Provides collated information on novel coronavirus (SARS-CoV-2) biology, including replication, genetics, and pathogenesis

    Discusses the pathogenesis of various emerging and re-emerging SARS coronaviruses

    Summarizes prevention with potential therapeutics against novel SARS-CoV-2 and COVID-19.

    Highlights prevention and control strategies for COVID-19 and novel SARS-CoV-2 infection

    Reviews the host-pathogen interaction, host immune response and clinical manifestation of the human Coronavirus disease COVID-19

     

    About this book

     

    This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19.

    An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.

     

    Table of contents (17 chapters)

     

    Current Insight into the Novel Coronavirus Disease 2019 (COVID-19)

    Pages 1-8

    Saxena, Shailendra K. (et al.)

    Global Trends in Epidemiology of Coronavirus Disease 2019 (COVID-19)

    Pages 9-21

    Srivastava, Nishant (et al.)

    Morphology, Genome Organization, Replication, and Pathogenesis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

    Pages 23-31

    Kumar, Swatantra (et al.)

    Transmission Cycle of SARS-CoV and SARS-CoV-2

    Pages 33-42

    Yadav, Tushar (et al.)

    Host Immune Response and Immunobiology of Human SARS-CoV-2 Infection

    Pages 43-53

    Kumar, Swatantra (et al.)

    Clinical Characteristics and Differential Clinical Diagnosis of Novel Coronavirus Disease 2019 (COVID-19)

    Pages 55-70

    Sharma, Raman (et al.)

    Coronavirus Infection Among Children and Adolescents

    Pages 71-79

    Kar, Sujita Kumar (et al.)

    COVID-19: An Ophthalmological Update

    Pages 81-93

    Ankita, (et al.)

    Laboratory Diagnosis of Novel Coronavirus Disease 2019 (COVID-19) Infection

    Pages 95-107

    Padhi, Abhishek (et al.)

    Therapeutic Development and Drugs for the Treatment of COVID-19

    Pages 109-126

    Maurya, Vimal K. (et al.)

    Prevention and Control Strategies for SARS-CoV-2 Infection

    Pages 127-140

    Srivastava, Nishant (et al.)

    Classical Coronaviruses

    Pages 141-150

    Jaiswal, Nitesh Kumar (et al.)

    Emergence and Reemergence of Severe Acute Respiratory Syndrome (SARS) Coronaviruses

    Pages 151-163

    Baxi, Preeti (et al.)

    Preparing for the Perpetual Challenges of Pandemics of Coronavirus Infections with Special Focus on SARS-CoV-2

    Pages 165-186

    Chawla, Sonam (et al.)

    Preparing Children for Pandemics

    Pages 187-198

    Saxena, Rakhi (et al.)

    Coping with Mental Health Challenges During COVID-19

    Pages 199-213

    Kar, Sujita Kumar (et al.)

    Correction to: Transmission Cycle of SARS-CoV and SARS-CoV-2

    Pages C1-C1

    Yadav, Tushar (et al.)

     

     

  • 78600lei 720.00 lei

     

    This updated volume provides a practical guide to pancreatic pathology that covers recent changes in concepts and classifications. Potential pitfalls and mimics in pancreatic pathology are highlighted and illustrated, and guidance is provided regarding how to recognise and avoid them. There is a new chapter on transplant pathology, and more than 200 new macroscopic and microscopic images have been added. 

    Pathology of the Pancreas: A Practical Approach aims to enable readers to recognise the various pathological entities and provide the key information in their pathology reports, which is necessary for the individual patient’s further management. The book provides the diagnostic pathologist with a comprehensive, well-illustrated, and extensively cross-referenced approach to pancreatic pathology.

     

  • Cardiac Pathology: A Guide to Current Practice
    La comanda in aproximativ 4 saptamani
    78600lei 730.00 lei

     Description:

    This updated second edition provides a comprehensive overview of cardiac pathology. Clear illustrations of the common styles of dissection are provided along with the normal anatomy and histology. The chapters cover autopsy heart examination, ischemic heart disease, myocarditis, sudden death, valvular disease, transplant pathology, cardiomyopathy, cardiac neoplasia and congenital heart disease with a clear analysis of diagnostic criteria (macroscopic, microscopic and genetic) for both common cardiac diseases and those of less common types. The text is accompanied by high quality macroscopic and microscopic images and references to other specialty data sources. Cardiac Pathology: A Guide to Current Practice is aimed at established pathologists and trainees, as well as any clinician with an interest in cardiac disease. It will be of value to those working in cardiac surgery, cardiology and those in the autopsy/forensic fields.

     

    Table of contents:

    1.    Front Matter

    2.    The Normal Adult Heart and Methods of Investigation

    3.    Cardiac Electrophysiology

    4.    Cardiac Imaging

    5.    Current Therapeutics for Cardiac Disease

    6.    The Heart at Autopsy, Including Radiological Autopsy of the Heart

    7.    Embryology of the Heart

    8.    Ischaemic Heart Disease

    9.    Myocarditis

    10. Valvular Heart Disease

    11. Transplant Pathology

    12. Cardiomyopathies

    13. Cardiac Tumours

    14. Congenital Heart Disease

    15. Sudden Cardiac Death

     

  • 78000lei 730.00 lei

    Approximately ten percent of the world population are affected by kidney diseases, which often can only be diagnosed by renal biopsy. This practical guide offers an algorithmic, deductive approach to the interpretation of this complicated procedure, covering all technical methods used for diagnosis. This new edition includes an authoritative chapter on digital renal pathology, a topic inadequately covered in current literature.

    All chapters have been extensively revised in light of major advances in the understanding of the pathogenesis and clinicopathological features of renal disease. Written for practising pathologists and nephrologists, this text encompasses the entire spectrum of medical renal diseases in both pediatric and adult populations. Its numerous diagnostic algorithms provide a convenient overview and a helpful guide into the detailed text, directing the reader to major patterns of interest. Including online access to over 1000 photomicrographs and diagrams, this book is also of interest to trainees in nephrology and pathology.

    o     Situated on the midpoint between encyclopaedic and summary coverage

    o     Includes a 'clinical and pathologic' classification scheme, which does not require prior knowledge of what the diagnosis is to find the relevant entry

    o     Extensively revised to incorporate major advances in the pathogenesis, classification and molecular genetics of renal diseases in both native and transplant kidneys

    Table of Contents

    Foreword
    Preface to the first edition
    Preface to the second edition
    1. Renal development and anatomy William L. Clapp
    2. Renal biopsy: the nephrologist's viewpoint Samir V. Parikh, Alejandro Diez, Isabelle Ayoub, Anthony Alvarado and Brad H. Rovin
    3. Algorithmic approach to the interpretation of renal biopsy Xin Jin (Joseph) Zhou, Zoltan G. Laszik, Tibor Nadasdy and Vivette D. D'Agati
    4. Glomerular diseases associated with nephrotic syndrome and proteinuria Michael B. Stokes, Glen S. Markowitz and Vivette D. D'Agati
    5. Glomerular diseases associated primarily with asymptomatic or gross hematuria Xin Jin (Joseph) Zhou and Ramesh Saxena
    6. Infection-related glomerulonephritis, membranoproliferative pattern of glomerulonephritis and nephritic syndrome Xin Jin (Joseph) Zhou, Michael Kuperman, Nilum Rajora and Ramesh Saxena
    7. Glomerular diseases associated with crescentic glomerulonephritis (rapidly progressive glomerulonephritis) Anjali A. Satoskar and Tibor Nadasdy
    8. Systemic lupus erythematosus and other autoimmune diseases (mixed connective tissue disease, rheumatoid arthritis, and Sjogren's syndrome) Michael B. Stokes, Samih H. Nasr and Vivette D. D'Agati
    9. Metabolic diseases of the kidney Kuang-Yu Jen and Zoltan G. Laszik
    10. Thrombotic microangiopathies Zoltan G. Laszik
    11. Renal diseases associated with hematopoietic disorders or organized deposits Guillermo A. Herrera
    12. Tubulointerstitial diseases Shane M. Meehan and Tibor Nadasdy
    13. Hypertension and vascular diseases of the kidney Kuang-Yu Jen and Jean L. Olson
    14. Cystic and developmental diseases of the kidney Xin Jin (Joseph) Zhou and Ramesh Saxena
    15. The ageing kidney and end stage renal disease Xin Jin (Joseph) Zhou and Ramesh Saxena
    16. Pathology of renal transplantation Tibor Nadasdy, Anjali Satoskar and Gyongyi Nadasdy
    17. Digital renal pathology Anthony J. Demetris, Andrew Lesniak and Kumiko Isse
    Index.

  • 730.00 lei

     

    This is the first book to focus entirely on the role of pathology in cardiac transplantation, linked to the clinical perspective through clinical–pathological correlation, multidisciplinary team working, and collaborative research. It provides a scientific framework with up-to-date pathological protocols and classification schemes and guides the reader through the chronological phases of the transplant process in a step-by-step approach. Topics include end-stage heart failure with pathologies encountered in the native heart, current issues surrounding donor selection, the multiple faces of rejection pathology correlated with clinical management and immunology, other post-transplant complications, details of pediatric and combined heart/other organ transplantation, and a useful practical appendix. Many high-quality images and illustrative cases are presented, along with learning points and ample references.

    Transplantation medicine today is continuously changing as collaborative research into novel diagnostic techniques and immunosuppressive therapies translates into improved recipient management and survival. This book is aimed at practicing transplant pathologists and specialist trainees. It will also appeal to general pathologists and to physicians and surgeons involved in cardiac transplantation who need to understand the role of pathology in the clinical management of transplant recipients.

     

    Table of contents (25 chapters)

     

    • Cardiac Transplantation and the Contribution of Pathology

    Pages 3-10

    Burke, Margaret, MB, FRCPath (et al.)

    • Advanced End-Stage Heart Failure: Epidemiology and Management

    Pages 13-20

    Parissis, John (et al.)

    • Mechanical Circulatory Support in End-Stage Heart Failure: Bridge to Transplantation and Destination Therapy

    Pages 21-32

    Stepanenko, Alexander, MD (et al.)

    • Clinical Indications for Heart Transplantation

    Pages 33-40

    Tona, Francesco, MD, PhD (et al.)

    • Pathologies Encountered in Explanted Native Hearts

    Pages 41-99

    Leone, Ornella (et al.)

    • Pretransplant Endomyocardial Biopsy: When and Why