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  • 92.00 lei

    Almost daily we hear news stories, advertisements, and scientific reports that promise genetic medicine will make us live longer, enable doctors to identify and treat diseases before they start, and individualize our medical care. But surprisingly, a century ago eugenicists were making the same promises. The "Science of Human Perfection" traces the history of the promises of medical genetics and of the medical dimension of eugenics. The book also considers social and ethical issues that cast troublesome shadows over these fields. Keeping his focus on America, science historian Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and sceptically, lest pernicious interests trump our own.

  • 98.00 lei

    PKU (phenylketonuria) is a genetic disorder that causes severe cognitive impairment if it is not detected and treated with a strict and difficult diet. In a lifetime of practice, most physicians will never encounter a single case of PKU, yet every physician in the industrialized world learns about the disease in medical school and, since the early 1960s, the newborn heel stick test for PKU has been mandatory in many countries. Diane B. Paul and Jeffrey P. Brosco's beautifully written book explains this paradox. The development of state programs for early detection of and treatment for PKU is deservedly considered a great public health success story. Advocates have traded on this success to urge expanded newborn screening, to defend basic research in genetics, and to confront proponents of genetic determinism. When deployed for these purposes, treatment for PKU is typically represented as a simple matter of adhering to a low-phenylalanine diet. In reality, the challenges of living with PKU are daunting. In this first general history of PKU, a historian and a pediatrician explore how a rare genetic disease became the object of an unprecedented system for routine testing. "The PKU Paradox" is informed by interviews with scientists, clinicians, policy makers, and individuals who live with the disease. The questions it raises touch on ongoing controversies about newborn screening and what happens to blood samples collected at birth.

  • Story Within. Personal Essays on Genetics and Identity
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    98.00 lei

    In "The Story Within", authors share powerful experiences of living with genetic disorders. Their stories illustrate the complexities involved in making decisions about genetic diseases: whether to be tested, who to tell, whether to have children, and whether and how to treat children medically, if treatment is available. More broadly, they consider how genetic information shapes the ways we see ourselves, the world, and our actions within it. People affected by genetic disease respond to such choices in varied and personal ways. These writers reflect that breadth of response, yet they share the desire to challenge a restricted sense of what "health" is or whose life has value. They write hoping to expand conversations about genetics and identity – to deepen debate and generate questions. Whether they or their families are affected by Huntington's disease, Alzheimer's disease, cancer, genetic deafness or blindness, schizophrenia, cystic fibrosis, Tay-Sachs, hypertrophic cardiomyopathy, fragile X, or Fanconi anemia, their stories remind us that genetic health is complicated, dynamic, and above all, deeply personal.

  • 190.00 lei

    How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation? Cell Biology by the Numbers explores these questions―and dozens of others―providing a richly illustrated and handy reference for students and researchers in molecular and cell biology, chemistry, and biophysics. The book features question-driven vignettes and "back of the envelope" calculations that investigate some of the key numbers in cell biology. Readers will learn about the sizes, concentrations, rates, energies, and other numbers that describe and drive the living world.

  • 291.00 lei

    The sequencing of the human genome has been hailed as the most ground-breaking scientific event of our time. It will, in equal measure, offer insight into our collective history and our individual identities, and open up untold possibilities for the diagnosis, treatment and prevention of disease. Not since Crick and Watson's discovery of the structure of DNA has a scientific publication been greeted with such fanfare and expectation. In this fascinating and beautifully illustrated account, written and compiled by Carina Dennis and Richard Gallagher of Nature, the genome project is made uniquely accessible for a general readership. It offers an introduction to the basic biology and techniques, a guide to the main players and events in the history of genetic science, and a range of viewpoints on its impact and reception around the world, in addition to the full text of the research paper itself. An indispensable companion to the human genome, this will stand as the definitive reference guide, commemorating one of humankind's greatest achievements.

  • 654.00 lei

    This book addresses the biological, moral and legal issues around prenatal testing of late onset neurogenetic disease. The contributors focus specifically on Huntington's Disease, which is used as a model for other late onset neurogenetic diseases. The et

  • 94000lei 760.00 lei

    This is the only book that presents clinical cases to illuminate basic concepts of cardiovascular genetics and genomics as practitioners encounter them in day-to-day practice. The unique use of real-world case discussions facilitates the memorization and understanding of basic principles, which can be more readily applied to actual cases.

  • 777.00 lei

    This book provides the only comprehensive treatise available on Fanconi Anemia. It gives a detailed analysis from the clinical to the molecular levels of the disorder. It also allows insight into the mechanisms of responses to DNA damage, and the complex interactions of several previously unknown proteins. The book will give research students a platform for further investigation, and act as a source of information regarding experimental design.

  • 1,10300lei 1045.00 lei

    Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, Seventh Edition is the eagerly awaited new edition of the discipline–leading text that has been at the forefront of diagnosis, prevention, and treatment of fetal genetic disorders for over 36 years. The seventh edition continues the long–established tradition of excellence that has become synonymous with this text. The book builds on the foundations of preconception and prenatal genetic counseling and the original pillars of prenatal diagnosis while also providing authoritative coverage of exciting developments in non–invasive genetic testing and rapidly developing molecular techniques, including microarray analysis and next generation sequencing, that are revolutionizing the field. Chapters are once again authored by internationally recognized authorities in the field of prenatal diagnosis. The editors have added three entirely new chapters to this edition to complement the complete revision of existing content. The three new chapters focus on non–invasive prenatal screening, placental genetics, and the psychology of prenatal and perinatal grief. The broad–ranging coverage and international scope will ensure that the new edition maintains its role as the major repository for information on all aspects of prenatal diagnosis. The editors have brought together an invaluable collection of evidence–based facts bolstered by knowledge and decades of experience in the field. Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, 7th Edition is a timely update to this world–leading text.

  • 1570.00 lei

    Beicher & MacKay's Obstetrics, Gynaecology and the Newborn, 4th Edition is an update of the highly acclaimed Obstetrics and the Newborn, 3rd Edition and Illustrated Textbook of Gynaecology. It is the most up-to-date resource in Obstetrics and Gynaecology targetting those with fundamental understanding of this subject area and is written from the Australian perspective with incorporation of the latest RANZCOG guidelines. Experts throughout Australia and New Zealand have contributed content on the most prevalent topics encountered by obstetricians; gynaecologists and neonatologists today, ranging from global and indigenous reproductive health; sexual assault; gynaecological oncology through to neonatal assessment, malformations and transport.

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