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  • 20800lei 175.00 lei

     

    Efficiently master essential cell and molecular biology information!
    Now in its second edition, Lippincott Illustrated Reviews: Cell and Molecular Biology continues to provide a highly visual presentation of essential cell and molecular biology, focusing on topics related to human health and disease. It offers all the most popular features of the bestselling Lippincott Illustrated Reviews series, including abundant full-color, annotated illustrations, chapter overviews, an expanded outline format, chapter summaries, and review questions that link basic science to real-life clinical situations.

    • Master all the latest cell and molecular biology knowledge, thanks to revisions throughout, including updated unit overviews and chapter summaries, which set goals for understanding and re-emphasize essential concepts from each chapter.
    • Understand the practical applications with clinical boxes that reinforce key concepts by direct application to real-world scenarios, now with expanded information on specific cellular processes.
    • Visualize key concepts more clearly with the aid of nearly 250 full-color, annotated illustrations.
    • Extend your learning online with access to new animations and an interactive question bank.

     

  • 220.00 lei

     

    Description:


     Now over 70,000 copies sold!

    This comprehensively revised edition of Clinical Biochemistry offers essential reading for today’s students of medicine and other health science disciplines - indeed, anyone who requires a concise, practical introduction to the subject. Topics are clearly presented in a series of double-page ‘learning units’, each covering a particular aspect of clinical biochemistry. Four sections provide a core grounding in the subject:

    • Introducing clinical biochemistry gives an insight into how modern hospital laboratories work, and includes an entirely new series of learning units on the interpretation of test results
    • Core biochemistry covers the bulk of routine analyses, and their relevance to the clinical setting
    • Endocrinology provides an overview of endocrine investigations as well as a practical approach to thyroid, adrenal, pituitary and gonadal function testing
    • Specialised investigations embraces an assortment of other topics that students may encounter

    This edition represents the most radical revision of the book to date. Every learning unit has been examined and updated to reflect current developments and clinical best practice. Entirely new material includes a series of learning units on interpretation and analytical aspects of clinical biochemistry. Coverage of fluid biochemistry is now more comprehensive. New "Want to know more?" links throughout the book point readers to relevant further information.


     

    Table Of Contents:

    Part 1: Introducing clinical biochemistry

    1 The clinical biochemistry laboratory

    2 The use of the laboratory

    3 Interpretation of results: general

    4 Interpretation of results: diagnosis

    5 Interpretation of results: monitoring

    6 Analytical aspects

    Part 2: Core biochemistry

    7 Fluid and electrolytes: basic concepts

    8 Water and sodium balance: physiological mechanisms

    9 Hyponatraemia: pathophysiology

    10 Hyponatraemia: assessment and management

    11 Hypernatraemia

    12 Hyperkalaemia

    13 Hypokalaemia

    14 Intravenous fluid therapy

    15 Investigation of renal function (1)

    16 Investigation of renal function (2)

    17 Urinalysis

    18 Proteinuria

    19 Acute kidney injury

    20 Chronic kidney disease

    21 Acid-base: concepts and vocabulary

    22 Metabolic acid-base disorders

    23 Respiratory and mixed acid-base disorders

    24 Acid-base disorders: diagnosis and management

    25 Proteins and enzymes

    26 Immunoglobulins

    27 Myocardial infarction

    28 Liver function tests

    29 Jaundice

    30 Liver disease

    31 Glucose metabolism and diabetes mellitus

    32 Diagnosis and monitoring of diabetes mellitus

    33 Diabetic ketoacidosis

    34 Hypoglycaemia

    35 Calcium regulation and hypocalcaemia

    36 Hypercalcaemia

    37 Phosphate and magnesium

    38 Metabolic bone disease

    39 Osteoporosis and fragility fractures

    Part 3: Endocrinology

    40 Endocrine control

    41 Dynamic function tests

    42 Pituitary function

    43 Growth disorders and acromegaly

    44 Thyroid pathophysiology

    45 Hypothyroidism

    46 Hyperthyroidism

    47 Adrenocortical pathophysiology

    48 Hypofunction of the adrenal cortex

    49 Hyperfunction of the adrenal cortex

    50 Gonadal function

    51 Subfertility

    Part 4: Specialized investigations

    52 Nutritional assessment

    53 Nutritional support

    54 Parenteral nutrition

    55 The metabolic response to injury

    56 Gastrointestinal disorders

    57 Iron

    58 Zinc and copper

    59 Therapeutic drug monitoring

    60 Toxicology

    61 Metal poisoning

    62 Alcohol

    63 Ascites

    64 Pleural fluid

    65 Cerebrospinal fluid

    66 Identification of body fluids

    67 Lipoprotein metabolism

    68 Clinical disorders of lipid metabolism

    69 Hypertension

    70 Cancer and its consequences

    71 Tumour markers

    72 Multiple endocrine neoplasia

    73 Hyperuricaemia

    74 Myopathy

    75 Fetal monitoring and prenatal diagnosis

    76 Pregnancy

    77 Antenatal screening

    78 Screening the newborn for disease

    79 Paediatric biochemistry

    80 Inborn errors of metabolism

    81 Selected inherited disorders

    Case history comments

    Online self-assessment

       

     

  • 24400lei 225.00 lei

     

    Description:

    Concise writing, a focus on clinical applications, and superb illustrations make Netter’s Essential Biochemistry, by Peter Ronner, PhD, the perfect choice for a basic understanding of biochemistry.. A single expert voice, informed by the insights of a team of reviewers, provides continuity throughout the text, presenting essentials of biochemical principles step by step. Summary diagrams help you grasp key concepts quickly, and end-of-chapter questions reinforce key concepts.



    Features:

    • Provides a highly visual, reader-friendly approach to the challenging area of biochemistry.
    • Integrates the clinical perspective throughout the text, giving context and meaning to biochemistry.
    • Frames every chapter with helpful synopses and summaries, and ends each chapter with review questions that reinforce major themes.
    • Illustrates key concepts with beautifully clear drawings and diagrams of biochemical processes which are supplemented with art from the renowned Netter collection, bridging basic sciences with clinical practice.

    Table Of Contents:

     

    1. The Human Karyotype and the Structure of DNA
    2. DNA Repair and Therapy of Cancer
    3. DNA Replication
    4. Clinical Tests Based on DNA or RNA
    5. Basic Genetics for Biochemistry
    6. Transcription and RNA processing
    7. Protein Synthesis and Posttranslational Protein Processing
    8. Cell Cycle and Cancer
    9. The Structure of Proteins and Protein Aggregates in Degenerative Diseases
    10. Enzymes and Consequences of Enzyme Deficiencies
    11. Biological Membranes
    12. Collagen, Collagenopathies, and Diseases of Mineralization
    13. Pathologic Alterations of the Extracellular Matrix that Involve Fibrillin, Elastin, or Proteoglycans
    14. Heme Metabolism, Porphyrias, and Hyperbilirubinemia
    15. Iron Metabolism: Iron-Deficiency Anemia and Iron Overload
    16. Erythropoiesis, Hemoglobin Function, and the CBC
    17. Hemoglobinopathies
    18. Carbohydrate Transport, Carbohydrate Malabsorption, and Lactose Intolerance
    19. Glycolysis and its Regulation by Hormones and Hypoxia
    20. Fructose and Galactose Metabolism: Hereditary Fructose Intolerance and Galactosemia
    21. Pentose Phosphate Pathway, Oxidative Stress, and Glucose 6-Phosphate Dehydrogenase Deficiency
    22. Citric Acid Cycle and Thiamine Deficiency
    23. Oxidative Phosphorylation and Mitochondrial Diseases
    24. Glycogen Metabolism and Glycogen Storage Diseases
    25. Gluconeogenesis and Fasting Hypoglycemia
    26. Insulin and Counterregulatory Hormones
    27. Fatty acids, Ketone Bodies, and Ketoacidosis
    28. Triglycerides and Hypertriglyceridemia
    29. Cholesterol Metabolism and Hypercholesterolemia
    30. Metabolism of Ethanol and the Consequences of Alcohol Dependence Syndrome
    31. Steroid Hormones and Vitamin D
    32. Eicosanoids
    33. Signaling
    34. Digestion of Dietary Protein and Net Synthesis of Protein in the Body
    35. Protein degradation, Amino Acid Metabolism, and Nitrogen Balance
    36. One-Carbon Metabolism, Folate Deficiency, and Cobalamin Deficiency
    37. Pyrimidine Nucleotides and Chemotherapy
    38. Gout and Other Diseases Related to the Metabolism of Purine Nucleotides
    39. Diabetes
       

     

  • 230.00 lei

     

    Description:

    Praised by faculty and students for more than two decades, Lippincott® Illustrated Reviews: Biochemistry is the long-established go-to resource for mastering the essentials of biochemistry. This best-selling text helps students quickly review, assimilate, and integrate large amounts of critical and complex information, with unparalleled illustrations that bring concepts to life. Like other titles in the popular Lippincott® Illustrated Review Series, this text follows an intuitive outline organization and boasts a wealth of study aids that clarify challenging information and strengthen retention and understanding. This updated and revised edition emphasizes clinical application and features new exercises, questions, and accompanying digital resources to ready students for success on exams and beyond.

     

    Table of Contents:

     

    Unit I: Protein Structure and Function

    Chapter 1: Amino Acids and the Role of pH

    I. Overview

    II. Structure

    III. Acidic and Basic Properties

    IV. Chapter Summary

    Chapter 1: Interactive Questions

    Chapter 2: Protein Structure

    I. Overview

    II. Primary Structure

    III. Secondary Structure

    IV. Tertiary Structure

    V. Quaternary Structure

    VI. Protein Misfolding

    VII. Chapter Summary

    Chapter 2: Interactive Questions

    Chapter 3: Globular Proteins

    I. Overview

    II. Globular Hemeproteins

    III. Globin Gene Organization

    IV. Hemoglobinopathies

    V. Chapter Summary

    Chapter 3: Interactive Questions

    Chapter 4: Fibrous Proteins

    I. Overview

    II. Collagen

    III. Elastin

    IV. Chapter Summary

    Chapter 4: Interactive Questions

    Chapter 5: Enzymes

    I. Overview

    II. Nomenclature

    III. Properties

    IV. Mechanism of Enzyme Action

    V. Factors Affecting Reaction Velocity

    VI. Michaelis–Menten Kinetics

    VII. Enzyme Inhibition

    VIII. Enzyme Regulation

    IX. Enzymes in Human Blood

    X. Chapter Summary

    Chapter 5: Interactive Questions

    Unit II: Bioenergetics and Carbohydrate Metabolism

    Chapter 6: Bioenergetics and Oxidative Phosphorylation

    I. Overview

    II. Free Energy

    III. Free Energy Change

    IV. ATP: An Energy Carrier

    V. Electron Transport Chain

    VI. Phosphorylation of ADP to ATP

    VII. Chapter Summary

    Chapter 6: Interactive Questions

    Chapter 7: Introduction to Carbohydrates

    I. Overview

    II. Classification and Structure

    III. Dietary Carbohydrate Digestion

    IV. Chapter Summary

    Chapter 7: Interactive Questions

    Chapter 8: Introduction to Metabolism and Glycolysis

    I. Metabolism Overview

    II. Metabolism Regulation

    III. Glycolysis Overview

    IV. Glucose Transport into Cells

    V. Glycolysis Reactions

    VI. Hormonal Regulation

    VII. Alternate Fates of Pyruvate

    VIII. Chapter Summary

    Chapter 8: Interactive Questions

    Chapter 9: Tricarboxylic Acid Cycle and Pyruvate Dehydrogenase Complex

    I. Cycle Overview

    II. Cycle Reactions

    III. Energy Produced by the Cycle

    IV. Cycle Regulation

    V. Chapter Summary

    Chapter 9: Interactive Questions

    Chapter 10: Gluconeogenesis

    I. Overview

    II. Substrates

    III. Reactions

    IV. Regulation

    V. Chapter Summary

    Chapter 10: Interactive Questions

    Chapter 11: Glycogen Metabolism

    I. Overview

    II. Structure and Function

    III. Synthesis (Glycogenesis)

    IV. Degradation (Glycogenolysis)

    V. Glycogenesis and Glycogenolysis Regulation

    VI. Glycogen Storage Diseases

    VII. Chapter Summary

    Chapter 11: Interactive Questions

    Chapter 12: Monosaccharide and Disaccharide Metabolism

    I. Overview

    II. Fructose Metabolism

    III. Galactose Metabolism

    IV. Lactose Synthesis

    V. Chapter Summary

    Chapter 12: Interactive Questions

    Chapter 13: Pentose Phosphate Pathway and Nicotinamide Adenine Dinucleotide Phosphate

    I. Overview

    II. Irreversible Oxidative Reactions

    III. Reversible Nonoxidative Reactions

    IV. Uses of NADPH

    V. G6PD Deficiency

    VI. Chapter Summary

    Chapter 13: Interactive Questions

    Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins

    I. Glycosaminoglycan Overview

    II. Structure

    III. Synthesis

    IV. Degradation

    V. Mucopolysaccharidoses

    VI. Glycoprotein Overview

    VII. Oligosaccharide Structure

    VIII. Glycoprotein Synthesis

    IX. Lysosomal Glycoprotein Degradation

    X. Chapter Summary

    Chapter 14: Interactive Questions

    Unit III: Lipid Metabolism

    Chapter 15: Dietary Lipid Metabolism

    I. Overview

    II. Digestion, Absorption, Secretion, and Utilization

    III. Chapter Summary

    Chapter 15: Interactive Questions

    Chapter 16: Fatty Acid, Triacylglycerol, and Ketone Body Metabolism

    I. Overview

    II. Fatty Acid Structure

    III. Fatty Acid De Novo Synthesis

    IV. Fat Mobilization and Fatty Acid Oxidation

    V. Ketone Bodies: Alternative Fuel for Cells

    VI. Chapter Summary

    Chapter 16: Interactive Questions

    Chapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism

    I. Phospholipid Overview

    II. Phospholipid Structure

    III. Phospholipid Synthesis

    IV. Phospholipid Degradation

    V. Glycolipid Overview

    VI. Glycosphingolipid Structure

    VII. Glycosphingolipid Synthesis and Degradation

    VIII. Eicosanoids: Prostaglandins, Thromboxanes, and Leukotrienes

    IX. Chapter Summary

    Chapter 17: Interactive Questions

    Chapter 18: Cholesterol, Lipoprotein, and Steroid Metabolism

    I. Overview

    II. Cholesterol Structure

    III. Cholesterol Synthesis

    IV. Cholesterol Degradation

    V. Bile Acids and Bile Salts

    VI. Plasma Lipoproteins

    VII. Steroid Hormones

    VIII. Chapter Summary

    Chapter 18: Interactive Questions

    Unit IV: Nitrogen Metabolism

    Chapter 19: Amino Acids: Nitrogen Disposal

    I. Overview

    II. Overall Nitrogen Metabolism

    III. Dietary Protein Digestion

    IV. Nitrogen Removal from Amino Acids

    V. Urea Cycle

    VI. Ammonia Metabolism

    VII. Chapter Summary

    Chapter 19: Interactive Questions

    Chapter 20: Amino Acids: Degradation and Synthesis

    I. Overview

    II. Glucogenic and Ketogenic Amino Acids

    III. Amino Acid Carbon Skeleton Catabolism

    IV. Folic Acid and Amino Acid Metabolism

    V. Biosynthesis of Nonessential Amino Acids

    VI. Amino Acid Metabolism Disorders

    VII. Chapter Summary

    Chapter 20: Interactive Questions

    Chapter 21: Amino Acids: Conversion to Specialized Products

    I. Overview

    II. Porphyrin Metabolism

    III. Other Nitrogen-Containing Compounds

    IV. Chapter Summary

    Chapter 21: Interactive Questions

    Chapter 22: Nucleotide Metabolism

    I. Overview

    II. Structure

    III. Purine Nucleotide Synthesis

    IV. Deoxyribonucleotide Synthesis

    V. Purine Nucleotide Degradation

    VI. Pyrimidine Synthesis and Degradation

    VII. Chapter Summary

    Chapter 22: Interactive Questions

    Unit V: Integration of Metabolism

    Chapter 23: Metabolic Effects of Insulin and Glucagon

    I. Overview

    II. Insulin

    III. Glucagon

    IV. Hypoglycemia

    V. Chapter Summary

    Chapter 23: Interactive Questions

    Chapter 24: The Feed–Fast Cycle

    I. Overview of the Absorptive State

    II. Regulatory Mechanisms

    III. Liver: Nutrient Distribution Center

    IV. Adipose Tissue: Energy Storage Depot

    V. Resting Skeletal Muscle

    VI. Brain

    VII. Overview of the Fasted State

    VIII. Liver in Fasting

    IX. Adipose Tissue in Fasting

    X. Resting Skeletal Muscle in Fasting

    XI. Brain in Fasting

    XII. Kidney in Long-Term Fasting

    XIII. Chapter Summary

    Chapter 24: Interactive Questions

    Chapter 25: Diabetes Mellitus

    I. Overview

    II. Type 1 Diabetes

    III. Type 2 Diabetes

    IV. Chronic Effects and Prevention

    V. Chapter Summary

    Chapter 25: Interactive Questions

    Chapter 26: Obesity

    I. Overview

    II. Assessment

    III. Body Weight Regulation

    IV. Molecular Influences

    V. Metabolic Effects

    VI. Obesity and Health

    VII. Weight Reduction

    VIII. Chapter Summary

    Chapter 26: Interactive Questions

    Unit VI: Medical Nutrition

    Chapter 27: Nutrition: Overview and Macronutrients

    I. Overview

    II. Dietary Reference Intakes

    III. Energy Requirement in Humans

    IV. Acceptable Macronutrient Distribution Ranges

    V. Dietary Fats

    VI. Dietary Carbohydrates

    VII. Dietary Protein

    VIII. Nutrition Tools

    IX. Nutrition and the Life Stages

    X. Chapter Summary

    Chapter 27: Interactive Questions

    Chapter 28: Micronutrients: Vitamins

    I. Overview

    II. Folic Acid (Vitamin B9)

    III. Cobalamin (Vitamin B12)

    IV. Ascorbic Acid (Vitamin C)

    V. Pyridoxine (Vitamin B6)

    VI. Thiamine (Vitamin B1)

    VII. Niacin (Vitamin B3)

    VIII. Riboflavin (Vitamin B2)

    IX. Biotin (Vitamin B7)

    X. Pantothenic Acid (Vitamin B5)

    XI. Vitamin A

    XII. Vitamin D

    XIII. Vitamin K

    XIV. Vitamin E

    XV. Chapter Summary

    Chapter 28: Interactive Questions

    Chapter 29: Micronutrients: Minerals

    I. Overview

    II. Macrominerals

    III. Trace Minerals (Microminerals)

    IV. Ultratrace Minerals

    V. Chapter Summary

    Chapter 29: Interactive Questions

    Unit VII: Storage and Expression of Genetic Information

    Chapter 30: DNA Structure, Replication, and Repair

    I. Overview

    II. DNA Structure

    III. Steps in Prokaryotic DNA Replication

    IV. Eukaryotic DNA Replication

    V. Eukaryotic DNA Organization

    VI. DNA Repair

    VII. Chapter Summary

    Chapter 30: Interactive Questions

    Chapter 31: RNA Structure, Synthesis, and Processing

    I. Overview

    II. RNA Structure

    III. Prokaryotic Gene Transcription

    IV. Eukaryotic Gene Transcription

    V. Posttranscriptional Modification of RNA

    VI. Chapter Summary

    Chapter 31: Interactive Questions

    Chapter 32: Protein Synthesis

    I. Overview

    II. The Genetic Code

    III. Components Required for Translation

    IV. Codon Recognition by Transfer RNA

    V. Steps in Translation

    VI. Co- and Posttranslational Modifications

    VII. Chapter Summary

    Chapter 32: Interactive Questions

    Chapter 33: Regulation of Gene Expression

    I. Overview

    II. Regulatory Sequences and Molecules

    III. Regulation of Prokaryotic Gene Expression

    IV. Regulation of Eukaryotic Gene Expression

    V. Chapter Summary

    Chapter 33: Interactive Questions

    Chapter 34: Biotechnology and Human Disease

    I. Overview

    II. Restriction Endonucleases

    III. DNA Cloning

    IV. Probes

    V. Southern Blotting

    VI. Restriction Fragment Length Polymorphism

    VII. Polymerase Chain Reaction

    VIII. Gene Expression Analysis

    IX. Gene Therapy

    X. Transgenic Animals

    XI. Chapter Summary

    Chapter 34: Interactive Questions

    Chapter 35: Blood Clotting

    I. Overview

    II. Secondary Hemostasis—Fibrin Meshwork Formation

    III. Limiting Clotting

    IV. Primary Hemostasis—Platelet Plug Formation

    V. Chapter Summary

    Chapter 35: Interactive Questions

    Appendix

    Index

    Figure Sources

     

  • 250.00 lei

    Description:

    Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Practical, approachable, and perfect for today’s busy medical students and practitioners, BRS Biochemistry, Molecular Biology, and Genetics, Seventh Edition helps ensure excellence in class exams and on the USMLE Step 1. The popular Board Review Series outline format keeps content succinct and accessible for the most efficient review, accompanied by bolded key terms, detailed figures, quick-reference tables, and other aids that highlight important concepts and reinforce understanding.   This revised edition is updated to reflect the latest perspectives in biochemistry, molecular biology, and genetics, with a clinical emphasis essential to success in practice. New Clinical Correlation boxes detail the real-world application of chapter concepts, and updated USMLE-style questions with answers test retention and enhance preparation for board exams and beyond.

     

    Table of Contents:

     

    1. Fuel Metabolism and Nutrition: Basic Principles

    Overview

    I. Metabolic Fuels and Dietary Components

    II. The Fed or Absorptive State

    III. Fasting

    IV. Prolonged Fasting (Starvation)

    Review Test

    2. Basic Aspects of Biochemistry: Organic Chemistry, Acid–Base Chemistry, Amino Acids, Protein Structure and Function, and Enzyme Kinetics

    Overview

    I. A Brief Review of Organic Chemistry

    II. Acids, Bases, and Buffers

    III. Amino Acids and Peptide Bonds

    IV. Protein Structure

    V. Enzymes

    Review Test

    3. Gene Expression (Transcription), Synthesis of Proteins (Translation), and Regulation of Gene Expression

    Overview

    I. Nucleic Acid Structure

    II. Synthesis of DNA (Replication)

    III. Synthesis of RNA (Transcription)

    IV. Protein Synthesis (Translation of mRNA)

    V. Regulation of Protein Synthesis

    VI. Recombinant DNA and Medicine

    Review Test

    4. Cell Biology, Signal Transduction, and the Molecular Biology of Cancer

    Overview

    I. Compartmentation in Cells: Cell Biology and Biochemistry

    II. Cell Signaling by Chemical Messengers

    III. The Molecular Biology of Cancer

    IV. Cancer and Apoptosis

    V. Cancer Requires Multiple Mutations

    VI. Viruses and Human Cancer

    Review Test

    5. Generation of Atp from Metabolic Fuels and Oxygen Toxicity

    Overview

    I. Bioenergetics

    II. Properties of Adenosine Triphosphate

    III. Electron Carriers and Vitamins

    IV. Tricarboxylic Acid Cycle

    V. Electron Transport Chain and Oxidative Phosphorylation

    VI. Oxygen Toxicity and Free-Radical Injury

    Review Test

    6. Carbohydrate Metabolism

    Overview

    I. Carbohydrate Structure

    II. Proteoglycans, Glycoproteins, and Glycolipids

    III. Digestion of Carbohydrates

    IV. Glycogen Structure and Metabolism

    V. Glycolysis

    VI. Gluconeogenesis

    VII. Fructose and Galactose Metabolism

    VIII. Pentose Phosphate Pathway

    IX. Maintenance of Blood Glucose Levels

    Review Test

    7. Lipid and Ethanol Metabolism

    Overview

    I. Lipid Structure

    II. Membranes

    III. Digestion of Dietary Triacylglycerol

    IV. Fatty Acid and Triacylglycerol Synthesis

    V. Formation of Triacylglycerol Stores in Adipose Tissue

    VI. Cholesterol and Bile Salt Metabolism

    VII. Blood Lipoproteins

    VIII. Fate of Adipose Triacylglycerols

    IX. Fatty Acid Oxidation

    X. Ketone Body Synthesis and Utilization

    XI. Phospholipid and Sphingolipid Metabolism

    XII. Metabolism of the Eicosanoids

    XIII. Ethanol Metabolism

    Review Test

    8. Nitrogen Metabolism: Amino Acids, Purines, Pyrimidines, and Products Derived from Amino Acids

    Overview

    I. Protein Digestion and Amino Acid Absorption

    II. Addition and Removal of Amino Acid Nitrogen

    III. Urea Cycle

    IV. Synthesis and Degradation of Amino Acids

    V. Interrelationships of Various Tissues in Amino Acid Metabolism

    VI. Tetrahydrofolate, Vitamin B12, and S-Adenosylmethionine

    VII. Special Products Derived from Amino Acids

    Review Test

    9 Molecular Endocrinology and an Overview of Tissue Metabolism

    Overview

    I. Synthesis of Hormones

    II. General Mechanisms of Hormone Action

    III. Regulation of Hormone Levels

    IV. Actions of Specific Hormones

    V. Biochemical Functions of Tissues

    Review Test

    10. Human Genetics—An Introduction

    Overview

    I. Mendelian Inheritance Patterns

    II. Genes

    III. Mutations

    IV. Inheritance Patterns

    V. A Summary of Inheritance Patterns

    VI. Cytogenetics

    VII. Population Genetics

    VIII. Multifactorial Diseases (Complex Traits)

    IX. Triplet Repeat Expansions

    X. Imprinting

    XI. Epigenetics

    XII. The Genetics of Tumor Suppressors

    XIII. Metabolic Genetic Disorders Involving Carbohydrate and Lipid Pathways

    Review Test

    Comprehensive Examination

    Index

     

     

     


  • 38000lei 260.00 lei

    Table of Contents

    Preface
    SECTION I Structures & Functions of Proteins & Enzymes
    1 Biochemistry & Medicine
    2 Water & pH
    3 Amino Acids & Peptides
    4 Proteins: Determination of Primary Structure
    5 Proteins: Higher Orders of Structure
    SECTION II Enzymes: Kinetics, Mechanism, Regulation, & Role of Transition Metals
    6 Proteins: Myoglobin & Hemoglobin
    7 Enzymes: Mechanism of Action
    8 Enzymes: Kinetics
    9 Enzymes: Regulation of Activities
    10 The Biochemical Roles of Transition Metals
    SECTION III Bioenergetics
    11 Bioenergetics: The Role of ATP
    12 Biologic Oxidation
    13 The Respiratory Chain & Oxidative Phosphorylation
    SECTION IV Metabolism of Carbohydrates
    14 Overview of Metabolism & the Provision of Metabolic Fuels
    15 Carbohydrates of Physiological Significance
    16 The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid, & Amino Acid Metabolism
    17 Glycolysis & the Oxidation of Pyruvate
    18 Metabolism of Glycogen
    19 Gluconeogenesis & the Control of Blood Glucose
    20 The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism
    SECTION V Metabolism of Lipids
    21 Lipids of Physiologic Significance
    22 Oxidation of Fatty Acids: Ketogenesis
    23 Biosynthesis of Fatty Acids & Eicosanoids
    24 Metabolism of Acylglycerols & Sphingolipids
    25 Lipid Transport & Storage
    26 Cholesterol Synthesis, Transport, & Excretion
    SECTION VI Metabolism of Proteins & Amino Acids
    27 Biosynthesis of the Nutritionally Nonessential Amino Acids
    28 Catabolism of Proteins & of Amino Acid Nitrogen
    29 Catabolism of the Carbon Skeletons of Amino Acids
    30 Conversion of Amino Acids to Specialized Products
    31 Porphyrins & Bile Pigments
    SECTION VII Structure, Function, & Replication of Informational Macromolecules
    32 Nucleotides
    33 Metabolism of Purine & Pyrimidine Nucleotides
    34 Nucleic Acid Structure & Function
    35 DNA Organization, Replication, & Repair
    36 RNA Synthesis, Processing, & Modification
    37 Protein Synthesis & the Genetic Code
    38 Regulation of Gene Expression
    39 Molecular Genetics, Recombinant DNA, & Genomic Technology
    SECTION VIII Biochemistry of Extracellular & Intracellular Communication
    40 Membranes: Structure & Function
    41 The Diversity of the Endocrine System
    42 Hormone Action & Signal Transduction
    SECTION IX Special Topics (A)
    43 Nutrition, Digestion, & Absorption
    44 Micronutrients: Vitamins & Minerals
    45 Free Radicals & Antioxidant Nutrients
    46 Glycoproteins
    47 Metabolism of Xenobiotics
    48 Clinical Biochemistry
    SECTION X Special Topics (B)
    49 Intracellular Traffic & Sorting of Proteins
    50 The Extracellular Matrix
    51 Muscle & the Cytoskeleton
    52 Plasma Proteins & Immunoglobulins
    53 Red Blood Cells
    54 White Blood Cells
    SECTION XI Special Topics (C)
    55 Hemostasis & Thrombosis
    56 Cancer: An Overview
    57 The Biochemistry of Aging
    58 Biochemical Case Histories
    The Answer Bank
    Index

     


  • 280.00 lei

     

    Description:

    Clinical Chemistry considers what happens to the body’s chemistry when affected by disease. It provides introductory coverage of the scientific basis for biochemistry tests routinely used in medicine - including tests for the assessment of organ function, diagnosis and monitoring disease activity and therapy efficacy. Each topic area begins with a concise description of the underlying physiological and biochemical principles and then applies them to patient investigation and management. The regular use of case histories helps further emphasise clinical relevance and chapter key points, as well as provide a useful starting point for examination revision.

    The clear and engaging writing style appreciated by generations of readers has been retained in this latest (ninth) edition, while the content has been thoroughly updated throughout. The approach and scope of this trusted text makes it ideal for integrated medical curricula, for medical training and for students and practitioners of clinical and biomedical science.

    Updated to incorporate the latest changes in practice - including new tests and the most recent evidence-based guidance

    ‘Light bulb’ sections give practical advice and clarify difficult concepts or potential pitfalls

    New ‘Red flag’ boxes highlight the results which should cause immediate concern to clinicians

    Updated references to core guidelines reflect latest best practice

    Also BONUS materials - interactive clinical cases and MCQs - to reinforce interpretive skills, check understanding and aid exam preparation

     


    Table Of Contents:

     

    1. An Introduction to Biochemistry and Cell Biology


    2. Biochemical Investigations in Clinical Medicine


    3. Water, Sodium and Potassium


    4. Hydrogen Ion Homoeostasis and Blood Gases


    5. The Kidneys


    6. The Liver


    7. The Gastrointestinal Tract


    8. Clinical Nutrition


    9. The Hypothalamus and the Pituitary Gland


    10. The Adrenal Glands


    11. The Thyroid Gland


    12. The Gonads


    13. Disorders of Carbohydrate Metabolism


    14. Calcium, Phosphate and Magnesium


    15. Bones and Joints


    16. Plasma Proteins and Enzymes


    17 Lipids, Lipoproteins and Cardiovascular Disease


    18. Muscles, Nerves and Psychiatric?Disorders


    19. Inherited Metabolic Diseases


    20. Disorders of Haemoproteins, Porphyrins and Iron


    21. Metabolic Aspects of Malignant Disease


    22. Therapeutic Drug Monitoring and Chemical Aspects of Toxicology


    23. Clinical Chemistry at the Extremes of Age

       

     


  • 320.00 lei

    With this ninth edition, the Textbook of Biochemistry for Medical Students is entering in the 24th year of existence, the contents is now suitable for undergraduate students. Rapid advances in the area of molecular biology have been incorporated. Specific Learning Objectives provided at the beginning of each chapter to specify what student should learn from that chapter. NEW: Color coding used to represent enzyme names instead of numbers for better readability. NEW: Major pathways have been collated at a single place to make it more reader friendly. NEW: Important classifications, facts, tables, cyclic reactions, etc. have been depicted as Key Concepts at the end of chapters for quick revision. Relevant and significant mechanisms and theories are explained with the help of schematic diagrams and graphs. Chapters on clinical chemistry have been extensively updated and clinically relevant points are added. A major attraction of this edition is the incorporation of Clinical Case Studies in almost all the chapters to help students identify the clinical relevance of biochemistry. For integrated learning and early clinical exposure (which is a major highlight of the new curriculum), clinical chemistry and applied aspects are incorporated in Boxes, which are "nice to know" for students. Chapter summary is provided at the end of each chapter for quick recapitulation For last minute revision, Essay Questions, Short Answer Questions, Multiple Choice Questions and Viva Voce Questions are given at the end of each chapter which are compiled from the question papers of various universities from the last decade and have been rephrased as per the new curriculum. NEW: New Figures have been added for better reproducibility. Appendices provide useful information on abbreviations, normal reference values, conversion chart, recommended daily allowance of essential nutrients, and composition of nutrients in selected common food materials. 1200 figures, 200 tables and 200 boxes altogether making the book more student-friendly.

  • 35900lei 330.00 lei

     

    Description:

    Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine.

    You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions.

    Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the ‘-omics’. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine.

    Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today’s integrated courses.

    • Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer
    • Download the enhanced, interactive digital version (that comes with the printed book) for unique bonus content and anytime access to the complete contents - extras include:

    - a glossary for quick reference review of difficult concepts

    - additional clinical images, text and case studies to further relate essential concepts to modern practice

    - links to important further resources - including videos, databases, key guidelines and related literature

    - 150+ multiple-choice and USMLE-style questions to test your understanding and aid exam preparation

    Table Of Contents:

     

    Section 1: Introduction

    Chapter 1 : Introduction

    Section 2: Molecules and Cells

    Chapter 2 : Amino Acids and Proteins

    Chapter 3 : Carbohydrates and Lipids

    Chapter 4 : Membranes and Transport

    Section 3: Metabolism

    Chapter 5 : Hemoglobin and oxygen transport

    Chapter 6 : Catalytic Proteins - Enzymes

    Chapter 7 : Vitamins and Minerals

    Chapter 8 : Bioenergetics and Oxidative Metabolism

    Chapter 9 : Anaerobic metabolism of glucose carbohydrates in the red blood cell

    Chapter 10: The Tricarboxylic Acid Cycle

    Chapter 11: Oxidative Metabolism of Lipids in Liver and Muscle

    Chapter 12 : Biosynthesis and Storage of Carbohydrates in Liver and Muscle

    Chapter 13: Biosynthesis and Storage of Fatty Acids

    Chapter 14: Biosynthesis of Cholesterol and Steroids

    Chapter 15: Biosynthesis and Degradation of Amino Acids

    Chapter 16: Biosynthesis and Degradation of Nucleotides

    Chapter 17: Complex Carbohydrates: Glycoproteins

    Chapter 18: Complex Lipids

    Chapter 19: The Extracellular Matrix

    Section 4: Molecular basis of inheritance

    Chapter 20: Deoxyribonucleic Acid

    Chapter 21: Ribonucleic Acid

    Chapter 22: Protein Synthesis and Turnover

    Chapter 23: Regulation of Gene Expression: Basic Mechanisms

    Chapter 24: Genomics, Proteomics and Metabolomics

    Section 5: Signalling and Growth

    Chapter 25: Membrane Receptors and Signal Transduction

    Chapter 26: Neurotransmitters

    Chapter 27: Biochemical Endocrinology

    Chapter 28: Cellular Homeostasis: Cell Growth and Cancer

    Chapter 29: Aging

    Section 6: Fuels Nutrients and Minerals

    Chapter 30: Digestion and Absorption of Nutrients: The Gastrointestinal Tract

    Chapter 31: Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus

    Chapter 32: "Nutrients and diets"

    Chapter 33: Lipoprotein Metabolism and Atherogenesis

    Section 7: Specialized Tissues and Their Function

    Chapter 34: The Role of Liver in Metabolism

    Chapter 35: Water and Electrolytes Homeostasis

    Chapter 36: Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance)

    Chapter 37: Muscle: Energy Metabolism and Contraction Exercise

    Chapter 38: Bone Metabolism and Calcium Homeostasis

    Chapter 39: Neurochemistry

    Section 8: Blood and Immunity. Clinical Biochemistry

    Chapter 40: Blood and Plasma Proteins

    Chapter 41: Haemostasis and Thrombosis

    Chapter 42: Oxidative stress and inflammation

    Chapter 43: The Immune Response: Innate and adaptive immunity

    Appendix 1: Selected Clinical laboratory reference ranges

    Appendix 2: Case Studies

       

     

  • 505.00 lei

     

    CARTE NEPUBLICATA INCA!

     

     

    Plant Biochemistry, Fifth Edition, enables students to gain basic knowledge of the entire field, from photosynthesis to genetic engineering and its many commercial applications. Topics include cell structure and function of isoprenoids, phenylpropanoids and other secondary metabolites, and plant growth regulation and development. The text covers recent research findings and identifies areas of future research. This book is suitable for graduate students and advanced undergraduates in plant physiology, plant pathology, plant cell biology, and other plant sciences, researchers in industries actively involved in agribusiness, other biotechnology enterprises, and researchers in agronomy, agriculture, plant development and related areas.

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