Lippincott Illustrated Reviews: Biochemistry, Eighth edition, International Edition

 

Description:

Praised by faculty and students for more than two decades, Lippincott® Illustrated Reviews: Biochemistry is the long-established go-to resource for mastering the essentials of biochemistry. This best-selling text helps students quickly review, assimilate, and integrate large amounts of critical and complex information, with unparalleled illustrations that bring concepts to life. Like other titles in the popular Lippincott® Illustrated Review Series, this text follows an intuitive outline organization and boasts a wealth of study aids that clarify challenging information and strengthen retention and understanding. This updated and revised edition emphasizes clinical application and features new exercises, questions, and accompanying digital resources to ready students for success on exams and beyond.

 

 

Table of Contents:

 

 

 

Unit I: Protein Structure and Function

 

Chapter 1: Amino Acids and the Role of pH

I. Overview

II. Structure

III. Acidic and Basic Properties

IV. Chapter Summary

Chapter 1: Interactive Questions

Chapter 2: Protein Structure

I. Overview

II. Primary Structure

III. Secondary Structure

IV. Tertiary Structure

V. Quaternary Structure

VI. Protein Misfolding

VII. Chapter Summary

Chapter 2: Interactive Questions

Chapter 3: Globular Proteins

I. Overview

II. Globular Hemeproteins

III. Globin Gene Organization

IV. Hemoglobinopathies

V. Chapter Summary

Chapter 3: Interactive Questions

Chapter 4: Fibrous Proteins

I. Overview

II. Collagen

III. Elastin

IV. Chapter Summary

Chapter 4: Interactive Questions

Chapter 5: Enzymes

I. Overview

II. Nomenclature

III. Properties

IV. Mechanism of Enzyme Action

V. Factors Affecting Reaction Velocity

VI. Michaelis–Menten Kinetics

VII. Enzyme Inhibition

VIII. Enzyme Regulation

IX. Enzymes in Human Blood

X. Chapter Summary

Chapter 5: Interactive Questions

Unit II: Bioenergetics and Carbohydrate Metabolism

Chapter 6: Bioenergetics and Oxidative Phosphorylation

I. Overview

II. Free Energy

III. Free Energy Change

IV. ATP: An Energy Carrier

V. Electron Transport Chain

VI. Phosphorylation of ADP to ATP

VII. Chapter Summary

Chapter 6: Interactive Questions

Chapter 7: Introduction to Carbohydrates

I. Overview

II. Classification and Structure

III. Dietary Carbohydrate Digestion

IV. Chapter Summary

Chapter 7: Interactive Questions

Chapter 8: Introduction to Metabolism and Glycolysis

I. Metabolism Overview

II. Metabolism Regulation

III. Glycolysis Overview

IV. Glucose Transport into Cells

V. Glycolysis Reactions

VI. Hormonal Regulation

VII. Alternate Fates of Pyruvate

VIII. Chapter Summary

Chapter 8: Interactive Questions

Chapter 9: Tricarboxylic Acid Cycle and Pyruvate Dehydrogenase Complex

I. Cycle Overview

II. Cycle Reactions

III. Energy Produced by the Cycle

IV. Cycle Regulation

V. Chapter Summary

Chapter 9: Interactive Questions

Chapter 10: Gluconeogenesis

I. Overview

II. Substrates

III. Reactions

IV. Regulation

V. Chapter Summary

Chapter 10: Interactive Questions

Chapter 11: Glycogen Metabolism

I. Overview

II. Structure and Function

III. Synthesis (Glycogenesis)

IV. Degradation (Glycogenolysis)

V. Glycogenesis and Glycogenolysis Regulation

VI. Glycogen Storage Diseases

VII. Chapter Summary

Chapter 11: Interactive Questions

Chapter 12: Monosaccharide and Disaccharide Metabolism

I. Overview

II. Fructose Metabolism

III. Galactose Metabolism

IV. Lactose Synthesis

V. Chapter Summary

Chapter 12: Interactive Questions

Chapter 13: Pentose Phosphate Pathway and Nicotinamide Adenine Dinucleotide Phosphate

I. Overview

II. Irreversible Oxidative Reactions

III. Reversible Nonoxidative Reactions

IV. Uses of NADPH

V. G6PD Deficiency

VI. Chapter Summary

Chapter 13: Interactive Questions

Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins

I. Glycosaminoglycan Overview

II. Structure

III. Synthesis

IV. Degradation

V. Mucopolysaccharidoses

VI. Glycoprotein Overview

VII. Oligosaccharide Structure

VIII. Glycoprotein Synthesis

IX. Lysosomal Glycoprotein Degradation

X. Chapter Summary

Chapter 14: Interactive Questions

Unit III: Lipid Metabolism

Chapter 15: Dietary Lipid Metabolism

I. Overview

II. Digestion, Absorption, Secretion, and Utilization

III. Chapter Summary

Chapter 15: Interactive Questions

Chapter 16: Fatty Acid, Triacylglycerol, and Ketone Body Metabolism

I. Overview

II. Fatty Acid Structure

III. Fatty Acid De Novo Synthesis

IV. Fat Mobilization and Fatty Acid Oxidation

V. Ketone Bodies: Alternative Fuel for Cells

VI. Chapter Summary

Chapter 16: Interactive Questions

Chapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism

I. Phospholipid Overview

II. Phospholipid Structure

III. Phospholipid Synthesis

IV. Phospholipid Degradation

V. Glycolipid Overview

VI. Glycosphingolipid Structure

VII. Glycosphingolipid Synthesis and Degradation

VIII. Eicosanoids: Prostaglandins, Thromboxanes, and Leukotrienes

IX. Chapter Summary

Chapter 17: Interactive Questions

Chapter 18: Cholesterol, Lipoprotein, and Steroid Metabolism

I. Overview

II. Cholesterol Structure

III. Cholesterol Synthesis

IV. Cholesterol Degradation

V. Bile Acids and Bile Salts

VI. Plasma Lipoproteins

VII. Steroid Hormones

VIII. Chapter Summary

Chapter 18: Interactive Questions

Unit IV: Nitrogen Metabolism

Chapter 19: Amino Acids: Nitrogen Disposal

I. Overview

II. Overall Nitrogen Metabolism

III. Dietary Protein Digestion

IV. Nitrogen Removal from Amino Acids

V. Urea Cycle

VI. Ammonia Metabolism

VII. Chapter Summary

Chapter 19: Interactive Questions

Chapter 20: Amino Acids: Degradation and Synthesis

I. Overview

II. Glucogenic and Ketogenic Amino Acids

III. Amino Acid Carbon Skeleton Catabolism

IV. Folic Acid and Amino Acid Metabolism

V. Biosynthesis of Nonessential Amino Acids

VI. Amino Acid Metabolism Disorders

VII. Chapter Summary

Chapter 20: Interactive Questions

Chapter 21: Amino Acids: Conversion to Specialized Products

I. Overview

II. Porphyrin Metabolism

III. Other Nitrogen-Containing Compounds

IV. Chapter Summary

Chapter 21: Interactive Questions

Chapter 22: Nucleotide Metabolism

I. Overview

II. Structure

III. Purine Nucleotide Synthesis

IV. Deoxyribonucleotide Synthesis

V. Purine Nucleotide Degradation

VI. Pyrimidine Synthesis and Degradation

VII. Chapter Summary

Chapter 22: Interactive Questions

Unit V: Integration of Metabolism

Chapter 23: Metabolic Effects of Insulin and Glucagon

I. Overview

II. Insulin

III. Glucagon

IV. Hypoglycemia

V. Chapter Summary

Chapter 23: Interactive Questions

Chapter 24: The Feed–Fast Cycle

I. Overview of the Absorptive State

II. Regulatory Mechanisms

III. Liver: Nutrient Distribution Center

IV. Adipose Tissue: Energy Storage Depot

V. Resting Skeletal Muscle

VI. Brain

VII. Overview of the Fasted State

VIII. Liver in Fasting

IX. Adipose Tissue in Fasting

X. Resting Skeletal Muscle in Fasting

XI. Brain in Fasting

XII. Kidney in Long-Term Fasting

XIII. Chapter Summary

Chapter 24: Interactive Questions

Chapter 25: Diabetes Mellitus

I. Overview

II. Type 1 Diabetes

III. Type 2 Diabetes

IV. Chronic Effects and Prevention

V. Chapter Summary

Chapter 25: Interactive Questions

Chapter 26: Obesity

I. Overview

II. Assessment

III. Body Weight Regulation

IV. Molecular Influences

V. Metabolic Effects

VI. Obesity and Health

VII. Weight Reduction

VIII. Chapter Summary

Chapter 26: Interactive Questions

Unit VI: Medical Nutrition

Chapter 27: Nutrition: Overview and Macronutrients

I. Overview

II. Dietary Reference Intakes

III. Energy Requirement in Humans

IV. Acceptable Macronutrient Distribution Ranges

V. Dietary Fats

VI. Dietary Carbohydrates

VII. Dietary Protein

VIII. Nutrition Tools

IX. Nutrition and the Life Stages

X. Chapter Summary

Chapter 27: Interactive Questions

Chapter 28: Micronutrients: Vitamins

I. Overview

II. Folic Acid (Vitamin B9)

III. Cobalamin (Vitamin B12)

IV. Ascorbic Acid (Vitamin C)

V. Pyridoxine (Vitamin B6)

VI. Thiamine (Vitamin B1)

VII. Niacin (Vitamin B3)

VIII. Riboflavin (Vitamin B2)

IX. Biotin (Vitamin B7)

X. Pantothenic Acid (Vitamin B5)

XI. Vitamin A

XII. Vitamin D

XIII. Vitamin K

XIV. Vitamin E

XV. Chapter Summary

Chapter 28: Interactive Questions

Chapter 29: Micronutrients: Minerals

I. Overview

II. Macrominerals

III. Trace Minerals (Microminerals)

IV. Ultratrace Minerals

V. Chapter Summary

Chapter 29: Interactive Questions

Unit VII: Storage and Expression of Genetic Information

Chapter 30: DNA Structure, Replication, and Repair

I. Overview

II. DNA Structure

III. Steps in Prokaryotic DNA Replication

IV. Eukaryotic DNA Replication

V. Eukaryotic DNA Organization

VI. DNA Repair

VII. Chapter Summary

Chapter 30: Interactive Questions

Chapter 31: RNA Structure, Synthesis, and Processing

I. Overview

II. RNA Structure

III. Prokaryotic Gene Transcription

IV. Eukaryotic Gene Transcription

V. Posttranscriptional Modification of RNA

VI. Chapter Summary

Chapter 31: Interactive Questions

Chapter 32: Protein Synthesis

I. Overview

II. The Genetic Code

III. Components Required for Translation

IV. Codon Recognition by Transfer RNA

V. Steps in Translation

VI. Co- and Posttranslational Modifications

VII. Chapter Summary

Chapter 32: Interactive Questions

Chapter 33: Regulation of Gene Expression

I. Overview

II. Regulatory Sequences and Molecules

III. Regulation of Prokaryotic Gene Expression

IV. Regulation of Eukaryotic Gene Expression

V. Chapter Summary

Chapter 33: Interactive Questions

Chapter 34: Biotechnology and Human Disease

I. Overview

II. Restriction Endonucleases

III. DNA Cloning

IV. Probes

V. Southern Blotting

VI. Restriction Fragment Length Polymorphism

VII. Polymerase Chain Reaction

VIII. Gene Expression Analysis

IX. Gene Therapy

X. Transgenic Animals

XI. Chapter Summary

Chapter 34: Interactive Questions

Chapter 35: Blood Clotting

I. Overview

II. Secondary Hemostasis—Fibrin Meshwork Formation

III. Limiting Clotting

IV. Primary Hemostasis—Platelet Plug Formation

V. Chapter Summary

Chapter 35: Interactive Questions

Appendix

Index

Figure Sources

 

An aparitie	9 Feb. 2021
Autor	Emine E. Abali, Susan D. Cline, David S. Franklin, Dr. Susan M. Viselli Ph.D.
Dimensiuni	27.6 x 3 x 21.4 cm
Editura	LWW
Format	Paperback
ISBN	9781975155117
Limba	Engleza
Nr pag	649