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  • 11600lei 100.00 lei

    Fluid therapy is one of the most basic interventions spanning across all medical and surgical disciplines. Physicians need to understand the physiology of fluids and electrolytes before they can evaluate the extent to which disease pathophysiology has altered the balance, enabling them to determine the type and quantity of intravenous fluids required for treatment. This new edition is a practical guide to intravenous fluids and their administration to surgical patients. Divided into sixteen sections, the text begins with an overview of normal water balance and distribution of body fluid. The next sections cover the pharmacology of different types of intravenous fluid, followed by discussion on fluid therapy in different medical circumstances, and concluding with a chapter on fluid calculation. The second edition has been fully revised to provide the latest information in the field, and features new topics including fluid choice in the perioperative period and surgery and stress response. Key points Fully revised, new edition presenting latest information on intravenous fluids in surgery Discusses different types of fluid and their application in different circumstances Second edition includes several new topics Previous edition (9789350903957) published in 2013

  • 20000lei 160.00 lei

     Anesteziologia este o specialitate medicala interventionala complexa, in care inducerea farmacodinamica a conditiilor pe baza de analgezice, sedare sau somn si relaxare sunt imbinate cu masurile de reanimare si reechilibrare necesare mentinerii homeostazei.


    Cuprins:

    Cap. I- Introducere
    Cap. II- Anatomo-fiziologie celulara
    Cap. III- Celula nervoasa
    Cap. IV- Farmacocinetica anestezicelor
    Cap. V- Modul de actiune al anestezicelor generale asupra neuronilor si a SNC
    Cap. VI- Schema anatomo-functionala a sistemului nervos
    Cap. VII- Analgezia
    Cap. VIII- Somnul
    Cap. IX- Relaxarea
    Cap. X- Homeostazia
    Cap. XI- Aparatul de anestezie
    Cap. XII- Hemeostazia in chirurgie
    Cap. XIII- Bibliografie

  • Anesthesia Secrets
    La comanda in aproximativ 4 saptamani
    21000lei 185.00 lei

     

    Description:

     

    For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Anesthesia Secrets, 6th Edition offers practical, up-to-date coverage of the full range of essential topics in the practice of anesthesiology. This bestselling resource features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable.

    The proven Secrets Series® format gives you the most return for your time – succinct, easy to read, engaging, and highly effective.

    Fully revised and updated throughout, including protocols and guidelines that are continuously evolving and that increasingly dictate best practices.

    New chapters on Electrocardiogram Interpretation, Cardiac Physiology, Vasoactive Agents, Volume Assessment, Blood Pressure Disturbances, Mechanical Ventilation Strategies, Perioperative Point-of-Care Ultrasound and Echocardiography, Neuraxial Techniques, Peripheral Nerve and Trunk Blocks, Patient Safety, and Medical Ethics.  

    Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams.

    Features bulleted lists, mnemonics, practical tips from leaders in the field – all providing a concise overview of important board-relevant content.

    Portable size makes it easy to carry with you for quick reference or review anywhere, anytime.

     

     

    Table of Contents:

     

    Top 100 Secrets

    1: Fundamentals of Anesthetic Care

    Chapter 1: Introduction to anesthesia

    Chapter 2: Pre-operative evaluation

    Question/Answers

    Chapter 3: Airway management

    Chapter 4: Autonomic nervous system

    Questions/Answers

    Chapter 5: Cardiac physiology

    Chapter 6: Pulmonary physiology

    Chapter 7: Arterial blood gas analysis

    Chapter 8: Volume regulation and fluid replacement

    Chapter 9: Electrolytes

    Questions: Electrolytes

    Chapter 10: Coagulation

    Chapter 11: Transfusion therapy

    Chapter 12: Perioperative patient safety

    Allergic Reactions

    Operating Room Fires

    Patient Positioning

    Ophthalmic Complications

    Venous Air Embolism

    Chapter 13: Perioperative medical ethics

    2: Pharmacology

    Chapter 14: Inhaled anesthetics

    Questions/Answers

    Chapter 15: Intravenous anesthetics

    Chapter 16: Opioids

    Chapter 17: Neuromuscular blocking agents

    Chapter 18: Local anesthetics

    Chapter 19: Vasoactive agents

    3: Patient Monitoring and Procedures

    Chapter 20: Pulse oximetry

    Chapter 21: Capnography

    Chapter 22: Blood pressure monitoring and arterial catheterization

    Chapter 23: Central venous catheterization

    Chapter 24: Perioperative point-of-care ultrasound and echocardiography

    Chapter 25: Volume assessment

    Chapter 26: The anesthesia machine

    Chapter 27: Mechanical ventilation strategies

    Chapter 28: Electrocardiogram

    RBBB

    LBBB

    Frontal Plane

    QRS Morphology in Precordial Leads

    Rhythm

    Chapter 29: Pacemakers and internal cardioverter defibrillators

    4: Perioperative Problems

    Chapter 30: Blood pressure disturbances

    Chapter 31: Pulmonary complications

    Aspiration

    Laryngospasm

    Bronchospasm

    Extubation

    Chapter 32: Awareness during anesthesia

    Chapter 33: Temperature disturbances

    Chapter 34: Post-anesthetic care

    5: Anesthesia and Select Systemic Disease

    Chapter 35: Coronary artery disease and perioperative myocardial infarction

    Chapter 36: Heart failure

    Chapter 37: Valvular heart disease

    Chapter 38: Pulmonary hypertension

    Chapter 39: Obstructive lung disease: asthma and chronic obstructive pulmonary disease

    Chapter 40: Acute respiratory distress syndrome

    Chapter 41: Hepatic dysfunction and liver transplantation

    Chapter 42: Renal function and anesthesia

    Chapter 43: Intracranial and cerebrovascular disease

    Chapter 44: Intracranial hypertension and traumatic brain injury

    Chapter 45: Malignant hyperthermia and other myopathies

    Chapter 46: Degenerative neurological diseases and neuropathies

    Chapter 47: Diabetes mellitus

    Chapter 48: Nondiabetic endocrine disease

    Chapter 49: Obesity and obstructive sleep apnea

    Chapter 50: Alcohol and substance abuse

    6: Anesthesia and Select Patient Populations

    Chapter 51: Neonatal anesthesia

    Chapter 52: Pediatric anesthesia

    Chapter 53: Congenital heart disease

    Chapter 54: Fundamentals of obstetric anesthesia

    Chapter 55: Obstetric analgesia and anesthesia

    Chapter 56: High-risk obstetrics

    Chapter 57: Trauma anesthesia

    Chapter 58: The burned patient

    Chapter 59: Geriatric anesthesia

    7: Anesthesia and Select Surgical Procedures

    Chapter 60: Laparoscopic surgery

    Chapter 61: Major vascular surgery

    Chapter 62: Cardiac surgery: cardiopulmonary bypass

    Chapter 63: Thoracic surgery: lung isolation techniques

    Chapter 64: Spine surgery

    Chapter 65: Craniotomy

    Chapter 66: Shoulder operations

    Chapter 67: Electroconvulsive therapy

    8: Regional Anesthesia and Pain Management

    Chapter 68: Fundamentals of regional anesthesia

    Chapter 69: Peripheral nerve and trunk blocks

    Chapter 70: Nerve blocks for the head and neck

    Chapter 71: Neuraxial anesthesia and analgesia

    Chapter 72: Acute pain management

    Chapter 73: Chronic pain management

    Index

     

  • 22600lei 200.00 lei

    Top of Form

     

    Description:

    For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Critical Care Secrets, 6th Edition, features the Secrets’ popular question-and-answer format that also includes lists, tables, and an easy-to-read style - making reference and review quick, easy, and enjoyable.

    Table Of Contents:

    I. General ICU Care

    1. Glycemic Control in the ICU

    2. Early Mobility

    3. Sedation, Analgesia, Delirium

    4. Pain Management in the ICU

    5. Ethics and Palliative Care

    6. Fluid Therapy

    7. Nutrition in Critically Ill Patients

    8. Mechanical Ventilation

    9. Noninvasive Respiratory Support

    10. Weaning from Mechanical Ventilation and Extubation

    11. Quality Assurance and Patient Safety in the ICU

    II. Monitoring

    12. Pulse Oximetry, Capnography, and Blood Gas Analysis

    13. Hemodynamic Monitoring

    14. Neuromonitoring

    III. Procedures

    15. Cardiopulmonary resuscitation

    16. Arterial and Central Venous Catheters

    17. Critical Care Ultrasound

    18. Ventricular Assist Device

    19. Percutaneous Assist Devices

    20. Intra-Aortic Balloon Pumps

    21. Extracorporeal Membrane Oxygenation (ECMO)

    22. Tracheal Intubation and Airway Management

    23. Tracheotomy and Upper Airway Obstruction

    24. Chest Tubes and Pneumothorax

    25. Bronchoscopy

    26. Pacemakers and Defibrillators

    IV. Pulmonary

    27. Acute Pneumonia

    28. Asthma

    29. Chronic Obstructive Pulmonary Disease

    30. Acute Respiratory Failure/ARDS

    31. Hemoptysis

    32. Venous Thromboembolism and Fat Embolism

    V. Cardiology

    33. Heart Failure and Valvular Heart Disease

    34. Acute Myocardial Infarction

    35. Cardiac Arrhythmia

    36. Aortic Dissection

    37. Pericardial Disease (Pericardial Tamponade and Pericarditis)

    VI. Infectious Disease

    38. Sepsis and Septic Shock

    39. Endocarditis

    40. Meningitis and Encephalitis in the Intensive Care Unit

    41. Disseminated Fungal Infections

    42. Multidrug-Resistant Bacteria

    43. Skin and Soft Tissue Infections

    44. H1N1/Influenza

    45. Immunocompromised Host

    VII. Renal Disease

    46. Hypertensive Crises

    47. Acute Kidney Injury

    48. Renal Replacement Therapy and Rhabdomyolysis

    49. Hypokalemia and Hyperkalemia

    50. Hyponatremia and Hypernatremia

    VIII. Gastroenterology

    51. Upper and Lower Gastrointestinal Bleeding in the Critically Ill Patient

    52. Acute Pancreatitis

    53. Hepatitis and Cirrhosis

    IX. Endocrinology

    54. Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State

    55. Adrenal Insufficiency in the Intensive Care Unit

    56. Thyroid Disease in the ICU

    X. Hematology/Oncology

    57. Blood Products and Coagulation

    58. Thrombocytopenia and Platelets

    59. Disseminated Intravascular Coagulation

    XI. Neurology

    60. Coma

    61. Brain Death

    62. Status Epilepticus

    63. Stroke and Subarachnoid Hemorrhage

    64. Guillain-Barré Syndrome and Myasthenia Gravis

    65. Alcohol Withdrawal

    XII. Surgery and Trauma

    66. Burns and Frostbite

    67. Thoracic Trauma (Flail Chest and Pulmonary & Myocardial Contusion)

    68. Acute Abdomen and Peritonitis

    69. Organ Donation

    XIII. Emergency Medicine

    70. Disaster Medicine, Bioterrorism and Ebola

    71. Allergy and Anaphylaxis

    72. Hypothermia

    73. Heat Stroke

    XIV. Toxicology

    74. General Approach to Poisonings

    75. Analgesics and Antidepressants

    76. Toxic Alcohol Poisoning

    77. Cardiovascular Medications

    78. Neuroleptic Malignant Syndrome

    XV. Unique Patient Populations

    79. Care of the Critically Ill Pregnant Patient

    80. Care of the Obese patient

    81. Oncologic Emergencies

    82. Post-Intensive Care Syndrome & Chronic Critical Illness

    83. ICU Survivors

    XVI. Emerging Therapies

    84. Sepsis: Emerging Therapies

       

    Bottom of Form

     

  • Oxford Handbook of Critical Care
    La comanda in aproximativ 4 saptamani
    200.00 lei

    The fully revised, third edition of this bestselling Handbook describes best practice of critical care in a succinct, concise and clinically-orientated way. Covering the principles of general management, it includes therapeutic and monitoring devices, specific disorders of organ systems, as well as detailed information on drugs and fluids. New material has been added on key areas such as airway maintenance, dressing techniques, infection control, echocardiography, tissue perfusion monitoring, coma and more. With up-to-date references and invaluable clinical advice, there is also plenty of space to add notes or amend sections to suit local protocols.

    Patient-centred and practical, it will serve the consultant, trainee, nurse or other allied health professionals as both a reference and aide memoir. This is the indispensable Oxford Handbook for all those working within critical care.

  • Pocket Anesthesia (Pocket Notebook)
    La comanda in aproximativ 4 saptamani
    25200lei 205.00 lei

     

    Description:

     

    Providing fast access to the most relevant, evidence-based information in all areas of anesthesiology, Pocket Anesthesia, Fourth Edition, is a practical, up-to-date resource for residents, anesthesiologists, CRNAs, and medical students—both on the wards and in the operating room. This concise handbook, now spiral-bound, is designed for portability and quick reference, with information presented in a bulleted, outline format throughout. The Pocket Notebook Series format is ideal for today's fast-paced health care environment. Information is presented in a schematic, outline format, with diagrams and tables for quick, easy reference.

     

     

    Table of Contents:

     

    CONTENTS

    PREOPERATIVE PATIENT EVALUATION

    INTRODUCTION

    PREOPERATIVE PHYSICAL EXAMINATION

    PREOPERATIVE LABORATORY TESTING

    ELECTROCARDIOGRAM (ECG) TESTING

    CARDIAC RISK STRATIFICATION

    INFECTIVE ENDOCARDITIS (IE) ANTIBIOTIC PROPHYLAXIS

    PERIOPERATIVE β-BLOCKER THERAPY

    STATINS

    STENTS & ANTIPLATELET AGENTS

    CONDITIONS WHICH MAY REQUIRE DELAY OF SURGERY FOR OPTIMIZATION

    MEDICATIONS REQUIRING SPECIAL CONSIDERATIONS IN THE PERIOPERATIVE PERIOD

    INHALED ANESTHETICS

    INTRODUCTION

    INHALED ANESTHETIC UPTAKE

    MAJOR FACTORS AFFECTING UPTAKE

    Solubility

    Cardiac Output

    Alveolar–Venous Concentration Gradient

    OTHER FACTORS INFLUENCING UPTAKE

    Factors That Speed Rate of Induction (↑ Fa/Fi)

    ELIMINATION/RECOVERY

    DIFFUSION HYPOXIA

    MINIMUM ALVEOLAR CONCENTRATION (MAC)

    CLINICAL CONSIDERATIONS OF INHALED ANESTHETICS

    SYSTEMIC EFFECTS OF INHALED AGENTS

    INHALATIONAL ANESTHETICS, SPECIFIC COMMENTS

    Nitrous Oxide (N2O)

    Isoflurane

    Desflurane

    Sevoflurane

    Halothane

    Heliox (Helium–Oxygen Combination)

    INTRAVENOUS ANESTHETICS

    INTRODUCTION

    GENERAL PRINCIPLES

    PROPOFOL (DIPRIVAN)

    ETOMIDATE (AMIDATE)

    SODIUM THIOPENTAL (PENTOTHAL)

    METHOHEXITAL (BREVITAL)

    KETAMINE (KETALAR)

    DEXMEDETOMIDINE

    BENZODIAZEPINES (SEE TABLE—PHARMACOLOGY OF COMMONLY ENCOUNTERED BENZODIAZEPINES)

    ANALGESICS

    OPIOIDS (SEE ALSO CHAPTER 13, ACUTE PAIN MANAGEMENT)

    General Comments

    Fentanyl (Sublimaze IV, Fentora Buccal, Actiq Lozenge, Duragesic Transdermal)

    Remifentanil (Ultiva)

    Sufentanil (Sufenta)

    Alfentanil (Alfenta)

    Morphine (Astramorph, Duramorph, MS Contin, Others)

    Hydromorphone (Dilaudid)

    Meperidine (Demerol)

    Methadone (Dolophine)

    Oxycodone

    Codeine

    NMDA RECEPTOR ANTAGONIST & OPIATE AGONISTS

    Ketamine (Ketalar)

    Tramadol (Ultram)

    OPIATE ANTAGONISTS (SEE CHAPTER 2H)

    TRANSDERMAL/TOPICAL MEDICATIONS

    Fentanyl Transdermal (Duragesic)

    Lidocaine Patch, 5% (Lidoderm)

    NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS)

    NONSELECTIVE COX INHIBITORS

    Acetaminophen (Tylenol, Paracetamol, Ofirmev)

    Propionic Acid Derivatives: Ibuprofen, Naproxen, Ketoprofen, Diclofenac

    Ketorolac (Toradol)

    Aspirin, Acetylsalicylic Acid

    SELECTIVE COX-2 INHIBITORS

    Celecoxib (Celebrex)

    LOCAL ANESTHETICS

    MECHANISM OF ACTION

    STRUCTURE & CLASSIFICATION

    PHARMACODYNAMICS

    SPECIFIC CONSIDERATIONS

    Chloroprocaine

    Lidocaine

    Bupivacaine

    Liposomal Bupivacaine (Exparel®)

    Ropivacaine

    Tetracaine

    Cocaine

    Topical Anesthesia for Minor Procedures (Pediatric IV Placement)

    ADDITIVES TO ENHANCE LOCAL ANESTHETICS

    LOCAL ANESTHETIC SYSTEMIC TOXICITY (LAST)

    LA Toxicity Treatment

    Methemoglobinemia (Normal Hemoglobin Oxidized to Methemoglobin)

    NEUROMUSCULAR BLOCKING DRUGS AND REVERSAL AGENTS

    MECHANISM

    Nondepolarizing: Aminosteroids

    Nondepolarizing: Benzylisoquinolines

    Depolarizing: Succinylcholine

    ANTAGONISM OF NONDEPOLARIZING NEUROMUSCULAR BLOCKADE

    Cholinesterase Inhibitors

    Physostigmine

    Sugammadex (Bridion®)

    VASOACTIVE, AUTONOMIC, AND CARDIOVASCULAR DRUGS

    INTRODUCTION

    ADRENERGIC AGONISTS AND VASOPRESSORS

    Dobutamine (Dobutrex)

    Dopamine (Intropin)

    Ephedrine (Generic)

    Epinephrine (Adrenaline)

    Isoproterenol (Isuprel)

    Phenylephrine (Neosynephrine)

    Norepinephrine (Levarterenol, Levophed)

    Vasopressin (Antidiuretic Hormone [ADH], Pitressin)

    Angiotensin II (Giapreza)

    PHOSPHODIESTERASE INHIBITORS

    Amrinone (Inocor, Inamrinone)

    Milrinone (Primacor)

    ADRENERGIC ANTAGONISTS

    α-Blockers

    Phenoxybenzamine (Dibenzyline)

    Phentolamine (Regitine, OraVerse)

    β-Blockers

    Labetalol (Normodyne, Trandate)

    Metoprolol (Lopressor, Toprol XL extended release)

    Esmolol (Brevibloc)

    Propranolol (Inderal)

    α-AGONISTS

    Clonidine (Catapres)

    Methyldopa (Aldomet)

    CALCIUM CHANNEL BLOCKERS (CCB)

    Diltiazem (Cardizem)

    Verapamil (Isoptin, Calan)

    Nicardipine (Cardene)

    Nifedipine (Procardia)

    Clevidipine (Cleviprex)

    VASODILATORS

    Fenoldopam (Corlopam)

    Hydralazine (Apresoline)

    Isosorbide Dinitrate (Isordil)

    Nitroglycerin (Tridil, Glycerol Trinitrate, Nitrostat, Nitrol, Nitro-Bid, Nitrolingual)

    Nitroprusside Sodium (Nipride, Nitropress)

    ANTIARRHYTHMICS

    Adenosine (Adenocard)

    Amiodarone (Cordarone)

    Lidocaine (Xylocaine)

    Procainamide (Pronestyl)

    HEART FAILURE

    Digoxin (Lanoxin)

    Nesiritide (B-Type Natriuretic Peptide, BNP, Natrecor)

    PHARMACOLOGY: ANTIBIOTICS AND HERBAL MEDICINES

    KEY POINTS

    ANTIBIOTICS FOR SURGICAL SITE INFECTION PROPHYLAXIS (PREINCISION DOSING)

    PROCEDURE-SPECIFIC SURGICAL PROPHYLACTIC ANTIBIOTIC RECOMMENDATIONS

    HERBAL MEDICINES AND SIDE EFFECTS

    OTHER DRUGS RELEVANT TO PRACTICE OF ANESTHESIA

    5HT3 ANTAGONISTS (ONDANSETRON, GRANISETRON, DOLASETRON)

    AMISULPRIDE

    ABCIXIMAB (REOPRO)

    ACARBOSE (PRECOSE)

    ACETAZOLAMIDE (DIAMOX)

    ALBUTEROL (PROVENTIL, VENTOLIN)

    ALVIMOPAN (ENTEREG)

    AMINOCAPROIC ACID (AMICAR)

    ANDEXANET ALFA (ANDEXXA; RECOMBINANT FACTOR XA)

    APIXABAN (ELIQUIS)

    ARGATROBAN (ACOVA)

    ATROPINE SULFATE

    BICARBONATE (SODIUM BICARBONATE)

    BICITRA (SODIUM CITRATE/CITRIC ACID)

    BIVALIRUDIN (ANGIOMAX)

    BOSENTAN (TRACLEER)

    BUMETANIDE (BUMEX)

    BUPRENORPHINE + NALOXONE (SUBOXONE)

    CALCIUM CHLORIDE (CaCl2); CALCIUM GLUCONATE (KALCINATE)

    CANAGLIFLOZIN (INVOKANA)

    CARBOPROST TROMETHAMINE (HEMABATE, 15-METHYL PROSTAGLANDIN F2α)

    CLOPIDOGREL (PLAVIX)

    CHLORAL HYDRATE (SOMNOTE)

    CHLOROTHIAZIDE (DIURIL)

    DABIGATRAN (PRADAXA)

    DALTEPARIN (FRAGMIN)

    DANTROLENE (DANTRIUM)

    DESMOPRESSIN ACETATE (DDAVP)

    DEXAMETHASONE (DECADRON)

    DIPHENHYDRAMINE (BENADRYL)

    DOLASETRON (ANZEMET)

    DROPERIDOL (INAPSINE)

    ENOXAPARIN (LOVENOX, LMWH)

    EPINEPHRINE, RACEMIC (VAPONEFRIN)

    EPOPROSTENOL (FLOLAN, PROSTACYCLIN, PROSTAGLANDIN I2 [PGI2])

    EPTIFIBATIDE (INTEGRILIN)

    ETHACRYNIC ACID (EDECRIN)

    EXENATIDE (BYETTA)

    FACTOR VIIA (NOVOSEVEN)

    FAMOTIDINE (PEPCID)

    FLUMAZENIL (MAZICON)

    FUROSEMIDE (LASIX)

    GLIPIZIDE (GLUCOTROL)

    GLUCAGON (GLUCAGEN)

    GLYBURIDE (DIABETA)

    GLYCOPYRROLATE (ROBINUL)

    GRANISETRON (GRANISOL, KYTRIL)

    HALOPERIDOL (HALDOL)

    HEPARIN, UNFRACTIONATED (UFH)

    HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART)

    HYDROCHLOROTHIAZIDE (HCTZ, MICROZIDE)

    HYDROCORTISONE (SOLU-CORTEF)

    HYDROXYZINE (VISTARIL, ATARAX)

    IDARUCIZUMAB (PRAXBIND)

    INDIGO CARMINE

    INDOCYANINE GREEN (CARDIO-GREEN)

    INSULIN, REGULAR

    IPRATROPIUM BROMIDE (ATROVENT)

    LEVETIRACETAM (KEPPRA)

    LEVOTHYROXINE (SYNTHROID, T4)

    LIRAGLUTIDE (VICTOZA)

    MAGNESIUM SULFATE (MgSO4)

    MANNITOL (OSMITROL)

    METFORMIN (GLUCOPHAGE)

    METHYLERGONOVINE (METHERGINE)

    METHYLENE BLUE (METHYLTHIONINE CHLORIDE, UROLENE BLUE)

    METHYLPREDNISOLONE (SOLU-MEDROL)

    METHYLNALTREXONE (RELISTOR)

    METOCLOPRAMIDE (REGLAN)

    Naloxone (Narcan)

    NITRIC OXIDE, INHALED (NO, iNO, INOMAX)

    OCTREOTIDE (SANDOSTATIN)

    OMEPRAZOLE (PRILOSEC)

    ONDANSETRON (ZOFRAN)

    ANTIDIABETICS

    OXYTOCIN (PITOCIN)

    PHENYTOIN (DILANTIN)

    PHOSPHORUS (PHOSPHO-SODA, NEUTRA-PHOS)

    PHYSOSTIGMINE (ANTILIRIUM)

    PIOGLITAZONE (ACTOS)

    POTASSIUM CHLORIDE (KCl, KDUR)

    PRASUGREL (EFFIENT)

    PROCHLORPERAZINE (COMPAZINE)

    PROMETHAZINE (PHENERGAN)

    PROSTAGLANDIN E1 (ALPROSTADIL, PROSTIN VR)

    PROTAMINE SULFATE

    RECOMBINANT FACTOR VIIA (NOVOSEVEN)

    REPAGLINIDE (PRANDIN)

    RIVAROXABAN (XARELTO)

    ROSIGLITAZONE (AVANDIA)

    SCOPOLAMINE PATCH (TRANSDERM SCÓP)

    SCOPOLAMINE INJECTION (HYOSCINE)

    SILDENAFIL (VIAGRA, REVATIO)

    SITAGLIPTIN (JANUVIA)

    SPIRONOLACTONE (ALDACTONE)

    THAM

    TISSUE PLASMINOGEN ACTIVATOR (ALTEPLASE, ACTIVASE, TPA)

    TRANEXAMIC ACID/TXA (CYKLOKAPRON)

    TROMETHAMINE (THAM ACETATE)

    VITAMIN K (PHYTONADIONE, AQUAMEPHYTON)

    WARFARIN (COUMADIN)

    ANESTHESIA EQUIPMENT

    GAS SUPPLY

    Oxygen: Path of Hospital Supply to Patient

    ANESTHESIA MACHINE (1SEE APPENDIX B FOR CHECKOUT RECOMMENDATIONS)

    BREATHING CIRCUIT: CONNECTS ANESTHESIA MACHINE TO PATIENT

    Closed-Circuit Anesthesia

    Airway Pressures

    Management of Increased Airway Pressures

    Open Breathing Systems (Historical, Not Typically Used in Modern Medicine)

    Mapleson Breathing Circuits A to E: Five Systems Described in 1950s

    Bain Circuit: Modification of Mapleson D

    ELECTRICAL SAFETY IN THE OR

    Electrosurgery

    Risk of Electrocution

    Ungrounded Power & Protection from Electric Shock

    AIRWAY MANAGEMENT

    INTRODUCTION

    AIRWAY ASSESSMENT

    AIRWAY DEVICES

    AIRWAY MANAGEMENT: OROTRACHEAL INTUBATION

    AIRWAY MANAGEMENT: NASOTRACHEAL INTUBATION

    AIRWAY MANAGEMENT: AWAKE FLEXIBLE FIBEROPTIC INTUBATION

    TRANSTRACHEAL PROCEDURES

    TECHNIQUES OF EXTUBATION

    DIFFICULT AIRWAY ALGORITHM

    ANESTHESIA TECHNIQUES

    INTRODUCTION

    PATIENT INTERVIEW AND EVALUATION

    PREMEDICATION

    ANESTHESIA TECHNIQUES: (GOALS)

    MONITORED ANESTHESIA CARE VS. GENERAL ANESTHESIA: ASA DEFINITIONS

    FLUMAZENIL (FOR ANTAGONISM OF BENZODIAZEPINE EFFECTS)

    INHALATIONAL INDUCTION

    Pediatric Technique

    Adult Inhalational Induction

    INTRAMUSCULAR INDUCTION

    RECTAL INDUCTION

    Characteristics

    Technique

    COMPONENTS OF ANESTHESIA

    “BALANCED ANESTHETIC” TECHNIQUE

    MONITORING OF NEUROMUSCULAR BLOCKADE/PARALYSIS

    Technique

    Train of Four

    Tetanic Stimulation

    Double-Burst Stimulation

    Post-tetanic Count

    Phase II Blockade with Succinylcholine

    AWARENESS

    Frequency of Awareness (from Prospective Study of 11,785 General Anesthetics)

    BRAIN FUNCTION MONITORING, DEPTH OF ANESTHESIA, AND AWARENESS

    BRAIN FUNCTION MONITORING & ANALGESIA

    TOTAL INTRAVENOUS ANESTHESIA (TIVA)

    GUIDELINES FOR USING PROPOFOL

    Induction of General Anesthesia

    Maintenance of General Anesthesia

    Sedation

    EXTUBATION & EMERGENCE

    Deep Extubation

    REGIONAL ANESTHESIA

    PERIPHERAL NERVE BLOCKS

    Introduction

    Preparation and Materials

    Contraindications—Similar to Those for Neuraxial Blockade

    Complications—Common to All Nerve Blocks

    General Considerations for Quality Improvement and Safety without US

    Ultrasound Basics

    Transducer Selection

    Imaging Plane

    Sonographic Appearance of Nerves

    General Considerations for Quality Improvement and Safety

    SUPERFICIAL CERVICAL PLEXUS (SCP) AND DEEP CERVICAL PLEXUS (DCP) BLOCKS

    BRACHIAL PLEXUS BLOCKS

    Interscalene Brachial Plexus Block

    Indications

    Supraclavicular Brachial Plexus Block

    Infraclavicular Brachial Plexus Block

    Axillary Brachial Plexus Block

    Distal Blocks of Peripheral Nerves of Upper Extremity (see Figure 6-2 for anatomy)

    DIGITAL NERVE BLOCK (UPPER EXTREMITY)

    LOWER-EXTREMITY BLOCKS

    Lumbar Plexus Block

    Femoral Nerve Block

    Obturator Nerve Block

    Lateral Femoral Cutaneous Block

    Adductor Canal Block

    Sciatic Nerve Block (Classic, Anterior, Subgluteal)

    Popliteal Block of Sciatic Nerve

    Saphenous Nerve Block

    Ankle Block (Fig. 6-4)

    INTRAVENOUS REGIONAL ANESTHESIA (BIER BLOCK)

    TRUNCAL BLOCKS OF PERIPHERAL NERVES

    Intercostal Nerve Blocks

    Transversus Abdominis Plane Block (TAP Block)

    Thoracic Paravertebral Block (PVB)

    SPINAL/EPIDURAL ANESTHESIA

    Neuraxial Anatomy (also see Figure 6-5)

    Physiologic Effects

    Contraindications to Placing a Neuraxial Block

    Patient Positioning for Block Placement

    SPINAL ANESTHESIA

    Continuous Spinal Anesthesia (CSA)

    EPIDURAL ANESTHESIA

    COMBINED SPINAL–EPIDURAL (CSE) TECHNIQUE

    CAUDAL ANESTHESIA

    POINT-OF-CARE ULTRASOUND (POCUS)

    POINT-OF-CARE ULTRASOUND (POCUS)

    FOCUSED CARDIAC ULTRASOUND

    Parasternal Long Axis (Fig. 7-1)

    Parasternal Short Axis (Fig. 7-2)

    Apical Four Chamber (Fig. 7-3)

    Subcostal Views (2)

    LUNG ULTRASOUND

    Ultrasound Artifact Analysis (and Pathology)

    Interstitial or Alveolar Disease (e.g., Pulmonary Edema, Consolidation, Contusion)

    Pneumothorax

    Pleural Effusion

    FOCUSED ASSESSMENT WITH SONOGRAPHY IN TRAUMA (FAST)

    ULTRASOUND-GUIDED VASCULAR ACCESS

    Indications

    Ultrasound Views

    AIRWAY ULTRASOUND (SEE Fig. 7-7)

    PERIOPERATIVE MONITORING

    PULSE OXIMETRY

    Information in Pulse Oximeter Waveform

    NONINVASIVE SPECTROPHOTOMETRIC HEMOGLOBIN MONITORING (e.g., MASIMO® RADICAL-7®)

    NEAR-INFRARED CORTICAL SPECTROPHOTOMETRY (e.g., MEDTRONIC INVOSTM, CASMED FORE-SIGHT ELITE®, MASIMO-O3®)

    NONINVASIVE BLOOD PRESSURE MONITORING (OSCILLOMETRIC SPHYGMOMANOMETRY)

    Causes of Artifacts in NIBP Monitoring

    Complications

    NONINVASIVE CONTINUOUS BLOOD PRESSURE, SV, SVV, SVR, AND CARDIAC OUTPUT MONITORING (EDWARDS CLEARSIGHT™)

    Potential Causes of Artifacts in Noninvasive Continuous Monitoring

    Complications

    TEMPERATURE MONITORING

    Complications of Hyperthermia

    Complications of Hypothermia (below 36°C)

    Artifacts

    Hazards

    Placement

    Malignant Hyperthermia

    ARTERIAL BLOOD PRESSURE (ABP) MONITORING

    SAFELY FLUSHING AN ARTERIAL LINE

    HAZARDS OF ARTERIAL LINE MONITORING

    CENTRAL VENOUS LINES & CENTRAL VENOUS PRESSURE (CVP) MONITORING

    Hazards of Central Line Placement

    Artifacts

    NORMAL CVP & CORRESPONDING ECG WAVEFORM (Fig. 8.2)

    INTRAVASCULAR VOLUME MONITORING BY DYNAMIC RESPONSE OF PULSE PRESSURE VARIATION (PPV): PULSION™ PICCO®; AND STROKE VOLUME VARIATION (SVV): EDWARDS™ VIGILEO®, FLO-TRAC® (USING PERIPHERAL ARTERIAL CATHETER, OPTIONAL CENTRAL VENOUS CATHETER)

    MEASUREMENT OF CARDIAC OUTPUT (ALSO SEE APPENDIX A)

    CONSIDERATIONS FOR PA THERMODILUTION CATHETER INSERTION & MONITORING

    NORMAL PA WAVEFORMS AS CATHETER IS PASSED FROM CVP (RA) TO RV TO PA TO PCWP

    “V” WAVES IN A WEDGE TRACING

    VENTILATION TECHNIQUES

    INTRODUCTION AND OVERVIEW

    Common Ventilation Modes: Continuous Mandatory Ventilation

    MANY ADVANTAGES OF SPONTANEOUS BREATHING VS. POSITIVE-PRESSURE VENTILATION WHILE INTUBATED

    CAPNOGRAPHY

    Hazards of Capnography

    CAPNOGRAPHS (FIG. 9-2)

    FLOW–VOLUME LOOPS (FIG. 9-3)

    MECHANICAL VENTILATION: PROTECTIVE STRATEGIES

    Current Strategies to Prevent Volutrauma, Barotrauma, Atelectrauma, Tracheal Ischemia, & O2 Toxicity

    Specific Settings

    PRONE VENTILATION FOR SEVERE ARDS

    NONINVASIVE VENTILATION (NIV): CPAP VS. BIPAP VS. HIGH-FLOW NASAL CANNULA

    DISCONTINUING MECHANICAL VENTILATION (ALSO CALLED WEANING OR LIBERATING FROM MV)

    SIMV Plus PS is a Common Weaning Mode in Many ICUs

    FLUIDS, ELECTROLYTES, & TRANSFUSION THERAPY

    FLUID MANAGEMENT

    Fluid Compartments

    Assessing Volume Status

    Volume Deficits

    Volume Replacement

    Crystalloids & Colloids

    Notes on Specific Fluids

    APPROACH TO ACID–BASE ANALYSIS

    Strong Ion Difference (Stewart Acid/Base)

    ELECTROLYTES

    Hyponatremia (Na+ <135 mEq/L)

    Hypernatremia (Na+ >145 mEq/L)

    Hypokalemia (K <3.5 mEq/L)

    Hyperkalemia (K+ >5.5 mEq/L)

    Hypocalcemia (Ca2+ <8.4 mg/dL)

    Hypercalcemia (Ca2+ >10.3 mg/dL)

    Hypomagnesemia (Mg2+ <1.3 mEq/L)

    Hypermagnesemia (Mg2+ >2.5 mEq/L)

    Hypophosphatemia (PO43- 2.8 mg/dL)

    Hyperphosphatemia (PO43- >4.5 mg/dL)

    TRANSFUSION THERAPY

    Blood Typing Tests

    Emergency Transfusion

    COMMON BLOOD PRODUCTS

    Red Blood Cells (RBC)

    Packed Red Blood Cells (PRBC)

    Equation for Arterial O2 Content in Blood

    Calculating Allowable Blood Loss

    Whole Blood

    Platelets

    Fresh Frozen Plasma (FFP)

    Cryoprecipitate

    Factor VII (NovoSeven, eptacog alfa)

    DDAVP

    4-Factor Prothrombin Complex Concentrates

    TRANSFUSION COMPLICATIONS

    Infectious Complications

    Coagulopathic Complications

    Transfusion Reactions

    Metabolic Complications

    Immune Complications—Transfusion-Related Immunomodulation (TRIM)

    COAGULATION

    Disorders of Coagulation

    Coagulation Studies

    Platelet Inhibitors

    Bleeding Disorders (Coagulopathies)

    Hyperfibrinolysis

    Heparin-Induced Thrombocytopenia (HIT)

    Disseminated Intravascular Coagulation (DIC)

    Vitamin K Deficiency

    COMMON INTRAOPERATIVE PROBLEMS

    HYPOXIA

    Actions (Fig. 11-1)

    Additional Diagnostic Tests

    BRONCHOSPASM

    Causes

    Investigations

    Management

    HYPOTENSION

    Differential Diagnosis

    Investigations

    Treatment Options

    HYPERTENSION

    Differential Diagnosis

    Investigations/Treatment Options

    HYPERCARBIA

    Differential Diagnosis

    Investigations/Treatment Options

    HYPOCARBIA

    Differential Diagnosis

    Investigations/Treatment Options

    ↑ PEAK AIRWAY PRESSURES

    Differential Diagnosis

    Treatment

    OLIGURIA

    Differential Diagnosis

    Investigations/Treatment Options

    MYOCARDIAL ISCHEMIA/INFARCTION

    Etiology

    Investigations

    Treatment Options

    MALIGNANT HYPERTHERMIA

    BRADYCARDIA

    Differential Diagnosis

    Investigations/Treatment

    TACHYCARDIA

    Differential Diagnosis

    Treatment Options

    DELAYED EMERGENCE

    Differential Diagnosis

    Investigations/Treatment Options

    ANAPHYLAXIS

    Differential Diagnosis

    Clinical Manifestations

    Treatment Options

    Prevention

    LATEX ALLERGY

    Incidence/Risk Factors

    Mechanism

    Preoperative Evaluation

    Equipment/Drug Considerations

    Anesthetic Considerations

    Treatment

    GASTRIC ACID ASPIRATION OR VOMITING UPON INDUCTION OF ANESTHESIA

    Clinical Manifestations

    Management

    COMPLICATIONS OF LARYNGOSCOPY AND INTUBATION

    Causes

    General Complications

    Specific Complications

    PROCEDURES IN ANESTHESIA

    PERIPHERAL VENOUS ACCESS

    Indications

    Technique

    Complications

    RAPID INFUSION CATHETER (RIC LINE)

    Indications

    Technique

    ARTERIAL ACCESS (ALSO SEE CHAPTER 8, ON PERIOPERATIVE MONITORING)

    Indications

    Technique: Radial Artery

    Technique: Brachial Artery

    Technique: Axillary Artery

    Contraindications

    Complications

    CENTRAL VENOUS ACCESS (ALSO SEE CHAPTER 8, ON PERIOPERATIVE MONITORING)

    Indications

    Contraindications

    Technique: Internal Jugular Vein (IJ)

    Technique: Subclavian Vein (SC)

    Technique: Femoral Vein (Fem)

    Complications

    Ultrasound-Guided Central Line Placement

    One-look technique

    Real-Time Visualization of IJ

    Real-Time Visualization of SC

    INSERTION OF A PULMONARY ARTERY CATHETER (PAC) (ALSO SEE CHAPTER 8, ON PERIOPERATIVE MONITORING)

    Indications

    Contraindications

    Technique

    Complication: PA Perforation

    DECOMPRESSION OF A PNEUMOTHORAX (NEEDLE THORACOSTOMY)

    Indication

    Technique (Fig. 12-3)

    Complications

    INSERTION OF A NASOGASTRIC TUBE (NGT)

    Indication

    Contraindications

    Technique

    Complications

    ACUTE PAIN MANAGEMENT

    INTRODUCTION

    DEFINITIONS

    NORMAL PAIN MECHANISMS & PAIN PATHWAYS

    Pain Pathways

    PAIN ASSESSMENT & MEASUREMENT

    History & Physical Exam (see also Fig. 32-1)

    Pain Measurement

    ACUTE PAIN MANAGEMENT

    Treatment

    ANALGESIC DELIVERY SYSTEMS

    PO

    SC/IM

    IV

    Patient-Controlled Analgesia (PCA)

    Neuraxial Analgesia

    Epidural Opioids

    Troubleshooting Epidural Catheter Infusions

    Intrathecal Opioids

    MANAGING SIDE EFFECTS

    ACUTE ON CHRONIC PAIN

    Opioid Receptor Mixed Agonists/Antagonists

    Definitions

    PACU MANAGEMENT AND DISCHARGE

    HYPOTENSION

    Initial Diagnosis & Management

    Management of Specific Conditions

    Bleeding

    HYPERTENSION

    Diagnosis and Management

    RESPIRATORY AND AIRWAY PROBLEMS

    Respiratory Insufficiency: Diagnosis & Management

    Respiratory Insufficiency: Management of Specific Conditions

    NEUROLOGIC PROBLEMS

    Common Problems

    POSTOPERATIVE NAUSEA AND VOMITING (PONV)

    PACU DISCHARGE CRITERIA

    Guidelines for Discharge from Phase 2

    Common Discharge Issues

    COMPLICATIONS OF ANESTHESIA

    INTRODUCTION

    PERIPHERAL NERVE INJURY

    Classification of Peripheral Nerve Lesions

    Anesthesia-related Causes

    Duration of Ischemia

    Other Factors Impacting Peripheral Nerves

    AIRWAY/DENTAL COMPLICATIONS

    Airway Complications

    Dental Injuries

    Burns

    Electrocautery/Electrosurgical Unit

    Magnetic Resonance Imaging

    Perioperative Blindness

    ENHANCED RECOVERY AFTER SURGERY (ERAS)

    TRAUMA, BURN, AND CRITICAL CARE MANAGEMENT

    INTRODUCTION

    AIRWAY MANAGEMENT FOR TRAUMA

    Intubation Indications

    Intubation Considerations

    Induction Considerations

    Acute Spinal Cord Injury (ASCI)

    Intraoperative Trauma Management

    Emergence/Transport

    Fluid Resuscitation

    Nutrition

    Total Parenteral Nutrition (TPN)

    Glycemic Control in ICU Patients

    BURN MANAGEMENT

    Pathophysiology

    INTRAOPERATIVE MANAGEMENT: GENERAL CONSIDERATIONS

    Anesthesia for Burn Surgery

    SEPSIS AND SEPTIC SHOCK

    Screening for Early Sepsis

    Acute Physiology and Chronic Health Evaluation (APACHE) II Score

    Associated Problems in Sepsis

    Early Quantitative Fluid Resuscitation

    Markers of Resuscitation in Sepsis

    MANAGEMENT OF SEPSIS

    An Approach to Sedation of ICU Patients

    Transfusion of Red Blood Cells (RBCs) in the Critically-Ill Patient

    CARDIAC SURGERY

    NORMAL CARDIOVASCULAR PHYSIOLOGY

    Cardiac Cycle: Definitions & Equations

    COMMON DISEASE STATES AFFECTING THE HEART

    Determinants of Myocardial Perfusion

    Hypertension (HTN)

    Valvular Disease

    HEART BLOCKS/ARRHYTHMIAS (SEE CHAPTER 35, ELECTROCARDIOGRAM [ECG] INTERPRETATION)

    Bradyarrhythmias—HR <60 bpm

    Tachyarrhythmias—HR >100 bpm

    Intra-aortic Balloon Pump

    CARDIOVASCULAR IMPLANTABLE ELECTRONIC DEVICE (CIED)

    Anesthetic Considerations for Pacemakers

    Implantable Cardiac Defibrillator (ICD)

    CARDIOPULMONARY BYPASS MACHINE

    Cardiopulmonary Bypass Preanesthetic Management

    Potential Catastrophes During Bypass

    Alpha Stat Vs. pH Stat

    Postop Complications

    TRANSESOPHAGEAL ECHOCARDIOGRAPHY (TEE)

    CARDIAC PHARMACOLOGY (SEE CHAPTER 2F, VASOACTIVE, AUTONOMIC, AND CARDIOVASCULAR DRUGS)

    TRANSCATHETER AORTIC VALVE IMPLANTATION (TAVI)/ REPLACEMENT (TAVR)

    THORACIC SURGERY

    PREOPERATIVE EVALUATION FOR THORACIC SURGERY

    COMMON DISEASE STATES OF THE LUNG

    COPD

    Asthma

    Pulmonary Edema

    ARDS (see also Chapter 17, Trauma, Burn, and Critical Care Management)

    Restrictive Lung Disease

    Pulmonary Hypertension Management

    LUNG ISOLATION AND ONE-LUNG VENTILATION (OLV)

    Double-Lumen Tubes (DLTs)

    Bronchial Blockers

    Physiology of 1-Lung Ventilation

    Anesthesia for 1-Lung Ventilation

    Anesthetic Techniques—Specific Surgical Procedures

    GENERAL SURGERY

    INTRODUCTION

    ANESTHETIC CONSIDERATIONS IN ABDOMINAL SURGERY

    Preoperative Evaluation

    Anesthetic Management

    ALCOHOL ABUSE

    Preop Evaluation

    Anesthetic Considerations

    Postop Considerations

    ANESTHETIC MANAGEMENT: LIVER SURGERY

    General Considerations

    Management of Portal Hypertension

    Monitoring

    Anesthetic Technique

    Postop Care

    ANESTHETIC MANAGEMENT: LAPAROSCOPIC SURGERY

    General Considerations

    Anesthetic Technique: Laparoscopic Surgery

    Monitoring

    Postop Care

    LARGE INTESTINAL SURGERY

    Indications

    Preop Evaluation

    Anesthetic Management: Large Intestinal Surgery

    Postop Complications

    SMALL INTESTINAL SURGERY

    Indications

    Carcinoid Tumors/Carcinoid Syndrome

    Monitoring

    Anesthetic Management

    Postop Care

    PANCREATIC SURGERY

    Indications

    Monitoring

    Anesthetic Management

    Postop Care

    SPLENIC SURGERY

    Indications

    Preop Preparation

    Anesthetic Management

    Postop Care

    HEMORRHOIDECTOMY & DRAINAGE OF PERIRECTAL ABSCESS

    Anesthetic Management

    Postop Care

    INGUINAL HERNIORRHAPHY

    Anesthetic Management

    VENTRAL HERNIORRHAPHY

    Preop Considerations

    Monitoring

    Anesthetic Management

    APPENDECTOMY

    Preop Evaluation

    Anesthetic Management

    Postop Care

    CHOLECYSTECTOMY

    Anesthetic Management

    Postop Care

    Anesthesia for Aesthetic Surgery

    Practice Advisory on Liposuction

    BARIATRIC SURGERY

    ANESTHETIC MANAGEMENT: BARIATRIC SURGERY

    Types of Bariatric Surgery

    Preanesthetic Considerations

    Anesthetic Technique

    Airway Management

    Monitoring

    Postop Complications

    VASCULAR SURGERY

    OPEN VASCULAR PROCEDURES

    Abdominal Aortic Aneurysm (AAA) Repair

    Thoracoabdominal Aortic Aneurysm (TAAA) Repair

    Carotid Endarterectomy

    ENDOVASCULAR PROCEDURES

    Endovascular AAA Repair (EVAR)

    Carotid Stent Placement

    Distal Angioplasty/Thrombectomy

    PERIPHERAL VASCULAR SURGERY

    NEUROSURGERY AND ECT

    BASIC PRINCIPLES OF NEUROPHYSIOLOGY

    Cerebral Metabolic Rate (CMR), Cerebral Blood Flow (CBF), and Autoregulation (Fig. 23-1)

    Intracranial Pressure (ICP)

    CRANIOTOMY

    Anesthetic Management

    Awake Craniotomy

    INTRACRANIAL VASCULAR SURGERY: ANEURYSM CLIPPING & RESECTION OF ARTERIOVENOUS MALFORMATIONS (AVMS)

    Preoperative Evaluation

    Induction & Pinning

    Maintenance

    VENTRICULOPERITONEAL SHUNT PLACEMENT/OMMAYA RESERVOIR

    EPIDURAL, SUBDURAL, & INTRACEREBRAL HEMORRHAGE (ICH)

    TRAUMATIC BRAIN INJURY

    ELECTROCONVULSIVE THERAPY (ECT)

    Goals

    Agents

    Management

    INTERVENTIONAL RADIOLOGY

    Central Intra-arterial Thrombolysis/Thrombectomy

    SPECIFIC NEUROLOGIC DISORDERS

    Myasthenia Gravis (MG)

    Multiple Sclerosis

    Guillain–Barré Syndrome

    Parkinson Disease

    OTOLARYNGOLOGY (ENT) AND OPHTHALMOLOGY

    PROCEDURES IN OTOLARYNGOLOGY

    Functional Endoscopic Sinus Surgery (FESS)

    CSF Leak Repair

    Microdirect/Suspension Laryngoscopy (MDL) & Transbronchoscope ENT Procedures

    Medialization Thyroplasty (Vocal Cord Medialization)

    PROCEDURES ON THE INNER EAR AND MASTOID

    Indications

    Special Considerations

    Anesthetic Management

    Stapedectomy

    Myringotomy Tube Placement (Placement of Ear Tubes)

    TONSILLECTOMY/PAROTIDECTOMY/UVULOPALATOPHARYNGOPLASTY

    Tonsillectomy and Adenoidectomy

    Parotidectomy

    Uvulopalatopharyngoplasty (UPPP)

    TRACHEOSTOMY

    Indications

    Special Considerations

    Anesthetic Management

    Management of Existing Tracheostomy

    Management of Mature Tracheostomy (>7 d)

    Management of Fresh Tracheostomy

    PROCEDURES IN OPHTHALMOLOGY

    Special Considerations

    Special Medications in Ophthalmologic Population

    Cataract Surgery: Clear Corneal Phacoemulsification

    Strabismus Surgery

    Other Procedures

    Peribulbar Block (25G–27G, 25-mm needle)

    Retrobulbar Block (25G–27G, 3-cm needle)

    Subtenon’s Block (25G needle)

    RENAL SYSTEM AND UROLOGIC SURGERY

    EVALUATION OF RENAL FUNCTION

    Acute Kidney Injury

    Chronic Renal Failure

    ANESTHESIA FOR PATIENTS WITH RENAL DISEASE

    Effects of Anesthesia on Renal Function

    Indirect Effects of Anesthesia

    Direct Effects of Anesthesia

    MEDICATIONS TO AVOID OR USE WITH CAUTION IN RENAL FAILURE

    UROLOGIC SURGERY

    Cystoscopy/Ureteroscopy/TURBT

    ORTHOPEDIC SURGERY

    GENERAL VS. REGIONAL ANESTHESIA

    POSITIONING

    SPINE SURGERY

    Cervical Spine Surgery

    Thoracic/Lumbar Spine Surgery

    NEUROMONITORING (ALSO SEE CHAPTER 23, NEUROSURGERY AND ECT)

    Types of Monitoring

    Factors Affecting Monitoring

    COMPLICATIONS IN ORTHOPEDIC SURGERY

    ENDOCRINE SURGERY

    THYROID GLAND

    Hyperthyroidism

    Hypothyroidism

    PARATHYROID GLANDS

    Hyperparathyroidism

    Hypoparathyroidism

    Pheochromocytoma

    DIABETES MANAGEMENT

    ADRENAL INSUFFICIENCY

    Anesthesia for Adrenal Insufficiency

    Excess of Corticosteroids (Cushing Syndrome)

    Hyperaldosteronism (Conn Syndrome)

    POSTERIOR PITUITARY GLAND

    Diabetes Insipidus (DI)

    Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Secretion

    OBSTETRIC AND GYNECOLOGIC ANESTHESIA

    INTRODUCTION

    Labor Analgesia and Anesthesia for Cesarean Delivery

    Labor Analgesia

    Anesthetic Considerations in Labor

    Anesthesia for Cesarean Delivery

    APGAR SCORE

    POSTDURAL PUNCTURE HEADACHE (PDPH)

    ANTEPARTUM HEMORRHAGE

    Postpartum Hemorrhage (PPH)

    DRUGS USED ON THE LABOR AND DELIVERY UNIT

    HYPERTENSIVE DISORDERS OF PREGNANCY

    Preeclampsia

    Nonobstetric Surgery in Pregnancy

    ANESTHESIA FOR GYNECOLOGIC SURGERY

    PEDIATRIC ANESTHESIA

    ANATOMY

    Upper Airway

    Vascular Access

    PHYSIOLOGY

    Transition from Fetal to Neonatal Circulation

    Respiratory

    Cardiovascular

    Renal

    Hepatic

    Gastrointestinal

    Hematopoietic

    Neurologic

    Temperature Regulation

    PHARMACOLOGY

    Body Fluid Composition

    Organ System Maturity

    Protein Binding

    Receptors

    PREOPERATIVE EVALUATION

    Psychological Assessment

    Neurotoxicity of Anesthetic Agents

    OR EQUIPMENT AND SETUP

    Intravenous Fluids

    Emergency Drugs

    ANESTHESIA TECHNIQUES

    Induction

    Maintenance

    CLINICAL CONDITIONS

    Respiratory

    Secondary Smoke Exposure

    Cardiac

    Atrial & Ventricular Septal Defects (ASD/VSD)

    Metabolic

    Gastrointestinal

    Pediatric Congenital Syndromes

    NEONATAL & PEDIATRIC RESUSCITATION

    Neonatal Resuscitation Algorithm

    Pediatric Advanced Cardiac Life Support (Also see Chapter 37, Emergency Algorithms)

    POSTOPERATIVE NAUSEA & VOMITING

    OUTSIDE OF THE OPERATING ROOM ANESTHESIA

    GENERAL CONSIDERATIONS AND SAFETY

    CT AND MRI

    CT: General Considerations

    Special Procedures in the CT Suite

    MRI: General Considerations

    INTERVENTIONAL NEURORADIOLOGY

    General Considerations

    ENDOSCOPY AND ERCP

    General Considerations

    CHRONIC PAIN MANAGEMENT

    INTRODUCTION

    LOW BACK PAIN (LBP)

    Strength Testing

    Sensory Testing

    Interventional Pain Treatment

    LUMBAR SPINAL CANAL STENOSIS

    Pathophysiology

    Evaluation

    Treatment

    FAILED BACK SURGERY SYNDROME (FBSS)

    Pathophysiology

    Evaluation

    Treatment

    OSTEOARTHRITIS VS. RHEUMATOID ARTHRITIS

    PERIPHERAL NEUROPATHIC PAIN

    ALGORITHM FOR MANAGEMENT OF NEUROPATHIC PAIN

    Peripheral Neuropathy

    POSTHERPETIC NEURALGIA (PHN)

    Symptoms

    Evaluation

    Treatment

    TRIGEMINAL NEURALGIA

    Incidence

    Etiology

    Symptoms

    Evaluation

    Treatment

    COMPLEX REGIONAL PAIN SYNDROME (CRPS)

    Signs and Symptoms of CRPS

    Treatment

    OCCIPITAL NEURALGIA

    Etiology

    Symptoms

    Evaluation

    Treatment

    HEADACHE

    PHANTOM LIMB PAIN

    Incidence

    Etiology

    Treatment

    VISCERAL PAIN

    Incidence

    Symptoms

    Evaluation

    FIBROMYALGIA

    Incidence

    Etiology

    Symptoms

    Evaluation

    Treatment

    CANCER PAIN

    Treatment

    ORGAN TRANSPLANTATION

    NONLIVING DONORS

    Cadaveric Organ Grafts

    Non–Heart Beating Organ Donors (NHBD) = Donation after Cardiac Death (DCD)

    Organ Preservation Techniques

    Intraoperative Management of Procurement

    LIVING KIDNEY DONOR

    Donor Criteria and Evaluation

    Anesthetic Considerations

    Surgical Procedure

    LIVING LIVER DONOR

    Donor Criteria

    Pediatric Recipients

    Morbidity & Mortality

    Surgical Procedure

    Anesthetic Considerations

    LIVING LUNG DONOR

    Morbidity & Mortality

    Anesthetic Considerations

    Surgical Procedure

    ANESTHESIA FOR KIDNEY TRANSPLANTATION

    Indications

    Preoperative Evaluation

    Intraoperative Management

    Induction & Maintenance

    Surgical Procedure

    Specific Intraoperative Considerations

    Postoperative Management

    ANESTHESIA FOR PANCREAS TRANSPLANTATION

    Indications

    Preoperative Evaluation

    Intraoperative Management

    Induction & Maintenance

    Specific Intraoperative Considerations

    Postoperative Management

    ANESTHESIA FOR LIVER TRANSPLANTATION (ALSO SEE CHAPTER 20, GENERAL SURGERY)

    General

    Preoperative Evaluation

    Intraoperative Management

    Induction and Maintenance

    Postoperative Management

    ANESTHESIA FOR LUNG TRANSPLANTATION

    Indications

    Indications for Heart–Lung Transplantation (HLT)

    Bilateral Sequential Lung Transplantation (BSLT)

    Living Donor Lung Transplantation (LDLT)

    Preoperative Evaluation

    Intraoperative Considerations

    Induction and Maintenance

    Surgical Procedure for Single-Lung Transplantation

    Specific Intraoperative Considerations

    Postoperative Management

    ANESTHESIA FOR HEART TRANSPLANTATION

    General Information

    Most Common Indications

    Preoperative Assessment

    Intraoperative Management

    Surgical Procedure

    Specific Intraoperative Considerations

    GERIATRIC ANESTHESIA

    GENERAL CONCERNS & CONSIDERATIONS

    EFFECTS OF AGING ON PHYSIOLOGY

    Cardiovascular System

    Pulmonary System

    Renal System

    Nervous System

    Assessing Frailty and Low Physiologic Reserve

    PHARMACOLOGY IN THE ELDERLY

    Factors Complicating Drug Administration

    Anesthetic Agent Selection and Administration

    ADDITIONAL PERIOPERATIVE CONSIDERATIONS

    Neuraxial/Regional Blocks

    Elderly Cognitive Assessment

    Postop Delirium (POD) and Periop Neurocognitive Disorder (PND)

    ELECTROCARDIOGRAM (ECG) INTERPRETATION

    ECG LEAD PLACEMENT & UTILITY

    STEPS FOR ECG INTERPRETATION

    ATRIOVENTRICULAR CONDUCTION SYSTEM

    VENTRICULAR ARRHYTHMIAS

    ETHICAL ISSUES & EVENT DISCLOSURE

    END-OF-LIFE ISSUES

    Pediatric/Minor (<18 y) Patients

    JEHOVAH’S WITNESSES (JW)

    DISCLOSURE AND APOLOGY—COMMUNICATING ABOUT UNANTICIPATED EVENTS

    EMERGENCY ALGORITHMS

    ADVANCED CARDIAC LIFE SUPPORT (ACLS)

    C-A-B (Chest compressions, Airway, Breathing)

    Specific Details (Also see Fig. 37-1)

    PEDIATRIC ADVANCED LIFE SUPPORT (PALS) (ALSO SEE CHAPTER 29, PEDIATRIC ANESTHESIA)

    RECOGNIZE THE NEED OF CPR

    Ventricular Fibrillation/Ventricular Tachycardia (Pulseless)

    Asystole and PEA

    Bradycardia with Cardiorespiratory Compromise

    Tachycardia with Cardiorespiratory Compromise

    Acute coronary syndromes: see Figure 37-5

    VASCULAR ACCESS/DRUG ADMINISTRATION

    COMMON MEDICAL PHRASES IN SPANISH

    INTRODUCTION

    APPENDIX

    APPENDIX A: FORMULAE AND QUICK REFERENCE

    CARDIOLOGY

    Fick Cardiac Output

    Shunts

    Valve Area

    Coronary Artery Anatomy (see Fig. A-1)

    PULMONARY

    NEPHROLOGY

    HEMATOLOGY

    OTHER

    SENSITIVITY AND SPECIFICITY CALCULATIONS

    Appendix B: ANESTHESIA MACHINE CHECKOUT & SETTING UP THE OR

    ANESTHESIA MACHINE CHECKOUT

    SETTING UP THE OR FOR A CASE: “SOAP M”

    S: Suction

    O: Oxygen

    A: Airway

    P: Pharmacy

    M: Machine/Monitors

    APPENDIX C: MANAGEMENT OF MALIGNANT HYPERTHERMIA (ALSO SEE CHAPTER 11)

    DIAGNOSIS VS. ASSOCIATED PROBLEMS

    Signs of MH

    Sudden/Unexpected Cardiac Arrest in Young Patients

    Trismus or Masseter Spasm with Succinylcholine

    ACUTE PHASE TREATMENT

    POSTACUTE PHASE

    APPENDIX D: COVID-19† CONSIDERATIONS

    INTRODUCTION

    POOR PROGNOSTIC INDICATORS

    PERIOPERATIVE CONSIDERATIONS

    AIRWAY RECOMMENDATIONS (OR AND OUT-OF-OR)

    INDEX

     

  • 29500lei 270.00 lei

    Now reflecting a greater focus on today's multidisciplinary approach to care, Critical Care Handbook of the Massachusetts General Hospital, 6th Edition, remains your go-to guide for practical, complete, and current information on medical and surgical critical care. The user-friendly, outline format is designed for rapid reference, providing reliable, hospital-tested protocols that reflect today's most advanced critical care practices. Key Features*Heavily revised to reflect today's need to include all care providers to optimize treatment*New section on Health Care Services, with chapters on handovers and transitions, long-term outcomes of ICU patients, EICU and electronic systems, quality improvement, and more*New chapters on critical care management of Ebola virus disease, ECMO and ventricular assist devices, and critical care of the obstetrical patient*New videos available online*Complete, concise, full-color coverage of this rapidly enlarging field*Convenient pocket size for on-the-go referenceNow with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:*Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

  • 30500lei 275.00 lei

    Apply today's best practices in anesthesiology! Relied on for over 30 years by practicing anesthesiologists and residents as well as nurse anesthetists, Clinical Anesthesia Procedures of the Massachusetts General Hospital offers you current, comprehensive, concise, consistent, and clinically relevant guidelines on all facets of anesthesia, perioperative care, critical care, and pain management from a host of seasoned experts. Key Features *Find the answers you need effortlessly through an easy-to-scan outline format that progresses intuitively from preoperative evaluation through administration of anesthesia to perioperative issues for each subject.*Focus on the clinical fundamentals needed for the safe delivery of anesthesia and perioperative care.*Achieve excellent outcomes using proven procedures from the internationally recognized Department of Anesthesia, Critical Care, and Pain Medicine at the Massachusetts General Hospital.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:*Complete content with enhanced navigation* A powerful search that pulls results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

  • 33500lei 280.00 lei

    Sharpen your clinical decision-making skills with this concise handbook of anesthesia care for children Written by the pediatric anesthesia faculty at Columbia University Medical Center, "Handbook of Pediatric Anesthesia" is a succinct guide to the practice of clinical anesthesia in neonates, infants, children, and adolescents. Each of the 89 chapters is devoted to a specific illness or disorder and is presented in a consistent, easy-access design. Every chapter includes a case description, perioperative considerations, anesthetic management, postoperative considerations, controversies, and surgical concerns for the illness discussed. Covering the entire breadth of the specialty, "Handbook of Pediatric Anesthesia" is an outstanding introductory text and an essential review for pediatric anesthesia board certification and recertification. It is especially valuable to residents and trainees as well as practicing anesthesiologists who do not manage pediatric cases on a regular basis. The book concludes with detailed appendices, including a Pediatric Critical Event Checklist and a Pediatric Drug Guide.

  • 38500lei 345.00 lei

    Description:

    This issue of Critical Care Clinics, Guest Edited by Dr. Kenneth McCurry and Dr. Ali Al-Khafaji, focuses on Critical Care of the Solid Organ Transplant Patient. Dr. McCurry’s section of the issue is devoted to Heart and Lung Transplants and includes the following topics: Long term outcomes of transplantation; Mechanical ventilation; Pulmonary hypertension therapy; Extracorporeal membrane oxygenation; Perioperative management of the lung graft following lung transplantation; Perioperative management of the heart graft following heart transplantation; Renal complications following lung and heart transplantation; and Infection and other complications following transplanation. Dr. Al-Khafaji’s section of the issue is devoted to Liver, Kidney, and Small Bowel Transplants and includes the following topics: The immediate postoperative period; Live donor liver transplant; Graft dysfunction and management; Extracorporeal devices; Infectious complication following solid organ transplants; and Cardiac, renal, neurological, and gastrointestinal complications.

     

    ·  Section I: Heart & Lung

    ·  Preface

    ·  Brief Overview of Lung, Heart, and Heart-Lung Transplantation

    ·  Key points

    ·  Introduction

    ·  Historical aspects of development of cardiothoracic transplantation and current trends

    ·  Recipient selection and outcomes

    ·  Immunosuppression

    ·  Summary

    ·  Bridging to Lung Transplantation

    ·  Key points

    ·  Introduction

    ·  Summary/discussion

    ·  Summary

    ·  Perioperative Management of the Lung Graft Following Lung Transplantation

    ·  Key points

    ·  Introduction

    ·  Primary graft dysfunction

    ·  Ventilatory strategies of the transplanted lungs

    ·  Hemodynamic management in the perioperative period

    ·  Perioperative fluid administration and cardiac output management

    ·  Postoperative considerations unique to patients with lung transplantation

    ·  Perioperative considerations in patients with different underlying disease presenting for lung transplantation

    ·  Gaps of knowledge and future directions in the perioperative care of the lung transplant patient

    ·  Perioperative Management of the Cardiac Transplant Recipient

    ·  Key points

    ·  Introduction

    ·  Hemodynamic monitoring

    ·  Coagulopathy, bleeding, and product administration

    ·  Vasoplegia

    ·  Inotropic and chronotropic support

    ·  Right ventricular failure and pulmonary hypertension

    ·  Arrhythmia

    ·  Ventilator support

    ·  Renal and volume status

    ·  Management of primary graft dysfunction

    ·  Renal Complications Following Lung Transplantation and Heart Transplantation

    ·  Key points

    ·  Introduction

    ·  Epidemiology, risk factors, and pathogenesis

    ·  Impact of renal failure

    ·  Diagnosis and management

    ·  Management of chronic renal impairment

    ·  Kidney transplantation after heart or lung transplantation

    ·  Summary

    ·  Infections in Heart and Lung Transplant Recipients

    ·  Key points

    ·  Introduction

    ·  Epidemiology

    ·  Risk factors

    ·  Specific clinical syndromes

    ·  Opportunistic infections

    ·  Section II: Liver, Kidney, and Small Bowel

    ·  Preface

    ·  Perioperative Management of the Liver Transplant Recipient

    ·  Key points

    ·  Overview

    ·  Process

    ·  Candidate selection: too sick for transplant?

    ·  Goals of care

    ·  Postoperative management

    ·  Hemodynamics

    ·  Neurologic

    ·  Respiratory

    ·  Renal

    ·  Gastrointestinal and nutrition

    ·  Infection

    ·  Hematologic considerations

    ·  Rehabilitation

    ·  Summary

    ·  Critical Care Management of Living Donor Liver Transplants

    ·  Key points

    ·  Introduction

    ·  The surgical procedure

    ·  The donor

    ·  The recipient

    ·  Summary

    ·  Graft Dysfunction and Management in Liver Transplantation

    ·  Key points

    ·  Introduction

    ·  Vascular issues

    ·  Primary nonfunction (and primary graft dysfunction)

    ·  Rejection

    ·  Post–liver transplant cholestasis

    ·  Intrahepatic cholestasis

    ·  Extrahepatic cholestasis

    ·  Donor factors affecting graft function

    ·  Extracorporeal Devices

    ·  Key points

    ·  Introduction

    ·  Critical care rational for extracorporeal liver support devices

    ·  Extracorporeal liver support systems

    ·  Bioartificial extracorporeal liver support in acute liver failure

    ·  Summary and challenges

    ·  Infectious Complications Following Solid Organ Transplantation

    ·  Key points

    ·  Introduction

    ·  Bloodstream infections/sepsis

    ·  Respiratory tract infections

    ·  Neurologic infections

    ·  Hepatobiliary infections

    ·  Enterocolitis

    ·  Genitourinary infections

    ·  Summary

    ·  Complications of Solid Organ Transplantation: Cardiovascular, Neurologic, Renal, and Gastrointestinal

    ·  Key points

    ·  Background

    ·  Cardiovascular complications

    ·  Neurologic complications after solid organ transplantation

    ·  Renal complications after solid organ transplantation

    ·  Gastrointestinal complications after solid organ transplantation

  • 36500lei 345.00 lei

    This issue of Critical Care Clinics, guest edited by Dr. Mitchell M. Levy, focuses on Biomarkers in Critical Care. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: The History of Biomarkers; Biomarkers for Identifying Infection; Procalcitonin: Where Are We Now?; Soluble TREM-1: Diagnosis or Prognosis?; Lubricin as a Biomarker in Sepsis; Check Point Inhibitors and Their Role in Immunosuppression in Sepsis; Metabolomics and the Microbiome as Biomarkers in Sepsis; Lactate: Where Are We Now?; Predicting Renal Dysfunction; Biomarkers in the Evolution of ARDS; Biomarkers and RV Dysfunction; Biomarkers and Precision Medicine: State of the Art; The Use of Biomarkers for Population Homogeneity in Clinical Trials; and The Future of Biomarkers.

  • 39400lei 345.00 lei

    This issue of Critical Care Clinics focuses on Rapid Response Systems and Fluid Resuscitation, with topics including: RRS Now; Triggering Criteria: Big Data; Triggering Criteria: Continuous Monitoring; Measuring instability; Surgery/Trauma RRT; Obstetric RRT; Difficult airway rapid response teams; and Sepsis rapid response teams.

    ·  Section I: Rapid Response Systems Edited By: Michael A. DeVita

    ·  Preface

    ·  The Afferent Limb of Rapid Response Systems: Continuous Monitoring on General Care Units

    ·  Key points

    ·  Introduction

    ·  Continuous monitoring

    ·  Alarm management

    ·  Discussion

    ·  Trigger Criteria: Big Data

    ·  Key points

    ·  Introduction

    ·  Big data in the hospital wards

    ·  Big data, event prediction, and event detection

    ·  Medical emergency teams and risk stratification of hospitalized patients

    ·  Summary

    ·  Surgical Rescue in Medical Patients: The Role of Acute Care Surgeons as the Surgical Rapid Response Team

    ·  Key points

    ·  Introduction

    ·  Failure to rescue: principles and applications to the medical population

    ·  Surgical rescue in medical patients

    ·  Surgical pathology in medical patients

    ·  A partnership for rescue

    ·  Crisis Teams for Obstetric Patients

    ·  Key points

    ·  Background and justification

    ·  Design and introduction

    ·  Usage of Condition O at Magee-Women’s Hospital and discussion

    ·  Summary

    ·  A Decade of Difficult Airway Response Team: Lessons Learned from a Hospital-Wide Difficult Airway Response Team Program

    ·  Key points

    ·  Introduction

    ·  Difficult Airway Response Team program: goals and design

    ·  Difficult Airway Response Team program: results

    ·  Lessons learned

    ·  Discussion

    ·  Sepsis Rapid Response Teams

    ·  Key points

    ·  Background

    ·  Sepsis rapid response teams: what are they? how are they different from other rapid response teams?

    ·  Outcomes after implementation of sepsis rapid response team/medical emergency team

    ·  The use of clinical assessment tools

    ·  Barriers in health care

    ·  Intensivist Presence at Code Events Is Associated with High Survival and Increased Documentation Rates

    ·  Key points

    ·  Introduction

    ·  Process

    ·  Results

    ·  Discussion

    ·  Summary

    ·  Section II: Fluid Resuscitation Edited By: Andrew D. Shaw and Sean M. Bagshaw

    ·  Preface

    ·  Applied Physiology of Fluid Resuscitation in Critical Illness

    ·  Key points

    ·  Introduction

    ·  Cardiovascular physiology 101

    ·  Fluids

    ·  Crystalloids

    ·  Colloids

    ·  Summary

    ·  Does Fluid Type and Amount Affect Kidney Function in Critical Illness?

    ·  Key points

    ·  Introduction

    ·  Measuring renal dysfunction in critical illness

    ·  How useful is urine output?

    ·  Are fluids a required component of renal resuscitation?

    ·  Mechanisms of renal injury related to type of fluid

    ·  Sodium, chloride, and balanced solutions

    ·  Albumin solutions

    ·  Hydroxyethyl starch

    ·  Gelatin solutions

    ·  Summary

    ·  Blood Product Administration in the Critical Care and Perioperative Settings

    ·  Key points

    ·  Introduction

    ·  Overview of the critical care setting

    ·  Overview of the perioperative setting

    ·  Management in critical illness

    ·  Perioperative management

    ·  Perspective

     


  • 39400lei 350.00 lei

    Description:

    This issue of Critical Care Clinics, Guest Edited by Dr. Rinaldo Bellomo, focuses on Modern Critical Care Endocrinology. Article topics include: Diabetes insipidus and SIADH in the ICU; Estrogen therapy in ICU patients; The angiotensin family, ACE and ACE 2; Angiotensin II in vasodilatory shock; Vasopressin in vasodilatory shock; Hydrocortisone in vasodilatory shock; Erythropoietin in trauma and critical illness; HbA1c and permissive hyperglycemia in diabetic ICU patients; Osteoporosis and the critically ill patient; New oral agents for the treatment of diabetes; Melatonin in critical care; The incretins in ICU patients; Hepcidin; Thyroid hormone therapy in the ICU; and Hormonal therapy in organ donors.

     

    ·  Diabetes Insipidus and Syndrome of Inappropriate Antidiuretic Hormone in Critically Ill Patients

    ·  Key points

    ·  Introduction

    ·  Diabetes insipidus

    ·  Fluid resuscitation and hypernatremia correction

    ·  Nephrogenic diabetes insipidus

    ·  The syndrome of inappropriate antidiuretic hormone secretion

    ·  Summary

    ·  Hormone Therapy in Trauma Patients

    ·  Key points

    ·  Glucocorticoids therapy

    ·  Safety concerns

    ·  Other hormones therapies

    ·  Summary

    ·  Classic and Nonclassic Renin-Angiotensin Systems in the Critically Ill

    ·  Key points

    ·  Introduction

    ·  The circulating classic renin-angiotensin system

    ·  Physiology of the circulating classic renin-angiotensin system

    ·  The nonclassic renin-angiotensin system

    ·  Renin-angiotensin systems and the immune system

    ·  Angiotensin II in vasodilatory shock and sepsis

    ·  Angiotensin-converting enzymes in acute respiratory distress syndrome

    ·  Place of renin-angiotensin systems in acute kidney injury

    ·  Integration of renin-angiotensin system physiology in critical illness

    ·  Summary

    ·  Angiotensin II in Vasodilatory Shock

    ·  Key points

    ·  Introduction

    ·  Vasodilatory shock

    ·  Hemodynamic targets for management of vasodilatory shock

    ·  Angiotensin II physiology

    ·  Angiotensin II use in vasodilatory shock

    ·  Angiotensin II safety profile

    ·  Angiotensin II and special populations

    ·  Illustrative case and concepts on the practical application of angiotensin II

    ·  Summary

    ·  Vasopressin in Vasodilatory Shock

    ·  Key points

    ·  Introduction

    ·  Mechanisms of vasodilatory shock and vasoplegia

    ·  Vasopressin

    ·  Vasopressin and Vasodilatory Shock

    ·  Summary

    ·  Hydrocortisone in Vasodilatory Shock

    ·  Key points

    ·  Regulation of vascular smooth muscle tone and vasoplegia of sepsis

    ·  Clinical trials of hydrocortisone in septic shock

    ·  Practice recommendations

    ·  Summary and future questions

    ·  Erythropoietin in Critical Illness and Trauma

    ·  Key points

    ·  Introduction

    ·  History of erythropoietin

    ·  Structure of erythropoietin and mechanism of enhanced erythropoiesis

    ·  Anemia in critical illness

    ·  Erythropoietin as a red blood cell transfusion-sparing agent in critical illness

    ·  Erythropoietin—more than just erythropoiesis

    ·  Endogenous erythropoietin has protective effects following tissue injury

    ·  Exogenous erythropoietin may improve survival and reduces severe disability in trauma patients

    ·  Meta-analysis of randomized controlled trials of erythropoietin in critically ill trauma patients

    ·  Erythropoietin—the most protective dose, route, and frequency of administration in the critically ill

    ·  Erythropoietin—is it safe in critically ill trauma patients?

    ·  Nonerythropoietin ligands of the innate repair receptor

    ·  Summary

    ·  Hemoglobin A1c and Permissive Hyperglycemia in Patients in the Intensive Care Unit with Diabetes

    ·  Key points

    ·  Introduction

    ·  Assessing chronic glycemia in critically ill patients

    ·  Glycated hemoglobin A1c, acute hyperglycemia, and outcome

    ·  Glycated hemoglobin A1c, hypoglycemia, and outcome

    ·  Glycated hemoglobin A1c, glucose variability, and outcome

    ·  Permissive hyperglycemia

    ·  Summary

    ·  Osteoporosis and the Critically Ill Patient

    ·  Key points

    ·  Introduction

    ·  Summary

    ·  New Agents for the Treatment of Type 2 Diabetes

    ·  Key points

    ·  Introduction

    ·  Sodium-glucose cotransporter-2 inhibitors

    ·  Glucagon-like peptide-1 agonists

    ·  Dipeptidyl peptidase-4 inhibitors

    ·  Summary

    ·  Melatonin in Critical Care

    ·  Key points

    ·  Introduction

    ·  Sleep disorders and delirium in critically ill patients

    ·  Sepsis

    ·  Sedation and analgesia

    ·  Neuroprotection

    ·  Treatment and prevention of stress-induced gastric ulcers

    ·  Summary

    ·  Incretin Physiology and Pharmacology in the Intensive Care Unit

    ·  Key points

    ·  Incretin physiology

    ·  Incretins in type 2 diabetes

    ·  Recommendations for incretin-based therapies in the critically ill

    ·  Incretins in intensive care unit

    ·  Summary

    ·  Therapeutic Opportunities for Hepcidin in Acute Care Medicine

    ·  Key points

    ·  Introduction

    ·  History of discovery

    ·  Hepcidin mechanism of action

    ·  Catalytic free iron in acute illness

    ·  Hepcidin as an agent for siderotherapy

    ·  Use of hepcidin in acute illness

    ·  Summary

    ·  Thyroid Hormones in Critical Illness

    ·  Key points

    ·  Thyroid hormone physiology

    ·  Physiologic effects of thyroid hormone

    ·  Low triiodothyronine syndrome

    ·  Mechanism of the low triiodothyronine syndrome

    ·  Triiodothyronine treatment in critical illness

    ·  Summary

    ·  Hormonal Therapy in Organ Donors

    ·  Key points

    ·  Introduction

    ·  Brain death and sequelae

    ·  Hormonal therapy

    ·  Recommendations

    ·  Recommendations

    ·  Recommendations

    ·  Summary

  • 39400lei 350.00 lei

    This issue of Critical Care Clinics, edited by Dr. Kianoush Kashani in collaboration with Consulting Editor Dr. John Kellum, is focused on Intensive Care Unit Telemedicine. Topics in this issue include: ICU telemedicine program administration: from start to full implementation; ICU telemedicine multidisciplinary care teams; ICU telemedicine technology; Impact of ICU telemedicine on outcomes; Quality assurance of ICU telemedicine; ICU telemedicine cost-effectiveness and financial analyses; ICU telemedicine care models; ICU telemedicine in the era of big data, artificial intelligence, and computer clinical decision support systems; ICU Telemedicine: Innovations and Limitations; ICU telemedicine: provider-patient satisfaction; and ICU telemedicine services beyond medical management: Tele-pharmacy, tele-procedure, tele-dialysis, tele-stroke: evidence, benefits, risks, and legal ramifications.

     Table of contents:

    ·  Important Administrative Aspects of Critical Care Telemedicine Programs

    ·  Key points

    ·  Introduction

    ·  Discussion

    ·  Summary

    ·  TeleICU Interdisciplinary Care Teams

    ·  Key points

    ·  Introduction

    ·  The essential TeleICU team structure

    ·  TeleICU team members

    ·  Getting teams to work together: the Synergy Model

    ·  Communication is key

    ·  Varying intensive care unit environments

    ·  Potential team extensions

    ·  One or multiple hub sites?

    ·  Additional uses of the TeleICU team/technology

    ·  Summary

    ·  Tele-ICU Technologies

    ·  Key points

    ·  Introduction

    ·  History and evolving technology of telemedicine in the intensive care unit

    ·  Tele-ICU technology

    ·  Hardware and software specifications

    ·  Regulations and cybersecurity

    ·  Health information technology standards and interoperability

    ·  Vendors and Tele-ICU technologies

    ·  Technology is important, but it is not everything

    ·  Impact of Intensive Care Unit Telemedicine on Outcomes

    ·  Key points

    ·  Meta-analysis

    ·  Process of care outcomes

    ·  Association of intensive care unit and intensive care unit telemedicine integration with results

    ·  Hospital impacts

    ·  Patients and providers

    ·  Final thoughts

    ·  Quality Improvement and Telemedicine Intensive Care Unit: A Perfect Match

    ·  Key points

    ·  Introduction

    ·  Medical errors in the intensive care unit and increasing safety in tele-intensive care using quality improvement tools

    ·  Quality improvement methodology examples: plan–do–study–act cycles, define–measure–analyze–improve–control, and lean

    ·  Tele-intensive care and its role in enhancing intensive care unit quality of care

    ·  Continuous quality improvement by tele-intensive care

    ·  Leveraging current and future knowledge to enhance intensive care unit metrics by tele-intensive care

    ·  Resource use and project prioritization

    ·  Diffusion of best practices across all intensive care units

    ·  Impact of quality improvement by tele-intensive care on interhospital transfers

    ·  Continuous quality improvement use in tele-intensive care

    ·  Handoff communication

    ·  Summary

    ·  Evolution of the Intensive Care Unit Telemedicine Value Proposition

    ·  Key points

    ·  Early warning systems

    ·  Intensive care unit telemedicine patient monitoring systems

    ·  Automated acuity and transfer readiness

    ·  Communication for team harmony and patient safety

    ·  Intensive care unit telemedicine sign-in and -out procedures enhance situational awareness

    ·  Delivering medical management and documentation services: more than advice

    ·  Pathways for escalation

    ·  Workforce leveraging

    ·  Incremental staffing resources for nascent physiologic instability

    ·  Teamwork for continuous management

    ·  An interprofessional approach to logistical support

    ·  Decreased time to rescue

    ·  Logistical support to increased access to care

    ·  Financial performance: a matter of perspective

    ·  Summary

    ·  Intensive Care Unit Telemedicine Care Models

    ·  Key points

    ·  Introduction

    ·  Basic principles

    ·  Intensity of the care models

    ·  Quality improvement

    ·  Intensive care unit telemedicine as a model for medical education

    ·  Summary

    ·  Intensive Care Unit Telemedicine in the Era of Big Data, Artificial Intelligence, and Computer Clinical Decision Support Systems

    ·  Key points

    ·  Introduction

    ·  History

    ·  State of clinical decision support systems in the telemedicine intensive care unit

    ·  Future telemedicine intensive care unit applications of machine learning

    ·  Telemedicine intensive care unit clinical decision support system considerations

    ·  Summary

    ·  Intensive Care Unit Telemedicine: Innovations and Limitations

    ·  Key points

    ·  Introduction

    ·  Recent innovations in intensive care unit telemedicine

    ·  Opportunities for intensive care unit telemedicine innovation

    ·  Limitations

    ·  Summary

    ·  Satisfaction in Intensive Care Unit Telemedicine Programs

    ·  Key points

    ·  Introduction

    ·  Tools for evaluating patient and provider satisfaction in an intensive care unit telemedicine program

    ·  Factors that affect satisfaction

    ·  Standards for measuring satisfaction in an intensive care unit telemedicine program

    ·  Summary

    ·  Appendix 1. Teamwork Climate Scale and Safety Climate Scale items

    ·  Expansion of Telemedicine Services: Telepharmacy, Telestroke, Teledialysis, Tele–Emergency Medicine

    ·  Key points

    ·  Introduction

    ·  Telepharmacy

    ·  Telestroke

    ·  Teledialysis

    ·  Tele–emergency medicine

    ·  Other telehealth services


  • 39400lei 350.00 lei

    Description:

    This issue of Critical Care Clinics, guest edited by Drs. Marie Baldisseri, Mary Reed, and Randy Wax, in collaboration with Consulting Editor John Kellum, is devoted to Intensive Care Unit in Disaster. Topics in this issue include: Intensive care role in disaster management; Preparing the ICU for disaster; Augmenting capacity; Triage; Natural disasters; Biological/pandemic disasters; Chemical disasters; Radiation; Anthropogenic (terrorist/criminal act) disasters; Special populations (i.e., chronically ill, morbidly obese, pregnant); Pediatrics; Austere environments; Hospital as disaster Ground Zero; and Special considerations (i.e., mental health, ethics, public relations).

     Table of contents:

    ·  Intensive Care Role in Disaster Management Critical Care Clinics

    ·  Key points

    ·  Defining disaster

    ·  Why critical care medicine is important in disaster preparedness

    ·  How critical care expertise is integral in disaster preparedness and response

    ·  Summary

    ·  Preparing the Intensive Care Unit for Disaster

    ·  Key points

    ·  For what disaster should we prepare?

    ·  Who should be involved in hospital critical care disaster planning and how can they contribute?

    ·  How can we teach, test, and tweak the critical care disaster plan?

    ·  Summary

    ·  Augmenting Critical Care Capacity in a Disaster

    ·  Key points

    ·  Introduction

    ·  Preparation

    ·  Personnel

    ·  Supplies

    ·  Space

    ·  Structure

    ·  Virtual critical care

    ·  Summary

    ·  Triage

    ·  Key points

    ·  What is triage?

    ·  When to triage

    ·  Different types of disaster triage

    ·  How to triage and who should do it

    ·  What are the ethics of triage and how to govern triage?

    ·  What research is required on triage?

    ·  Summary

    ·  Natural Disasters

    ·  Key points

    ·  Introduction

    ·  Natural disaster aftermath

    ·  Disruption of the initial emergency response: the rescue stage

    ·  Summary

    ·  Intensive Care Unit Preparedness During Pandemics and Other Biological Threats

    ·  Key points

    ·  Introduction

    ·  Intensive care unit planning for pandemics

    ·  Planning for pandemics

    ·  Summary

    ·  Disasters Resulting from Radiologic and Nuclear Events

    ·  Key points

    ·  Introduction

    ·  Basic radiation physics

    ·  Patterns of injury from radiation

    ·  Initial assessment and management

    ·  Decontamination

    ·  Dose estimation/triage

    ·  Management of internal contamination

    ·  Initial assessment for internal contamination

    ·  Treatment of internal radiation contamination

    ·  Hospital and critical care management

    ·  Management issues of the patient with radiation injury and trauma

    ·  Disaster planning/all-hazard preparedness

    ·  Summary

    ·  Chemical Agents in Disaster: Care and Management in the Intensive Care Unit

    ·  Key points

    ·  Introduction

    ·  Lung agents

    ·  Nerve agents

    ·  Vesicants

    ·  Blood agents

    ·  Summary

    ·  Anthropogenic Disasters

    ·  Key points

    ·  Introduction

    ·  Blast trauma

    ·  Penetrating trauma

    ·  Blunt trauma

    ·  Penetrating trauma: stab wounds

    ·  Wildfire

    ·  Summary

    ·  Appendix 1: agents of natural and manmade disasters

    ·  Provision of Care for Critically Ill Children in Disasters

    ·  Key points

    ·  Introduction

    ·  Essentials of formulating a pediatric disaster plan

    ·  Special clinical considerations

    ·  Chemical, biologic, radiation, nuclear, and explosive disasters

    ·  Ethics

    ·  Summary

    ·  Special Populations: Disaster Care Considerations in Chronically Ill, Pregnant, and Morbidly Obese Patients

    ·  Key points

    ·  Introduction

    ·  Defining the problem

    ·  Special population planning and care

    ·  A framework for planning and response to disaster

    ·  Future directions

    ·  Summary

    ·  Principles and Practices of Establishing a Hospital-Based Ebola Treatment Unit

    ·  Key points

    ·  Introduction

    ·  Historical care and isolation of patients with ebola

    ·  Rationale for establishing a hospital-based ebola treatment unit

    ·  Clinical presentation of ebola

    ·  Key principles and practices for establishing a hospital-based establishment of treatment units

    ·  Summary

    ·  Supplementary data

    ·  Battling Superstorm Sandy at Lenox Hill Hospital: When the Hospital Is Ground Zero

    ·  Key points

    ·  Hypothesis

    ·  Introduction

    ·  Methods

    ·  Results

    ·  Internal medicine

    ·  Intensive care

    ·  Pulmonary

    ·  Surgery

    ·  Pathology

    ·  Summary

    ·  Disaster Ethics: Shifting Priorities in an Unstable and Dangerous Environment

    ·  Key points

    ·  Introduction

    ·  Principlism and theories of justice

    ·  Disasters and ethical challenges to systems as usual (organizational ethics)

  • 38500lei 350.00 lei

    The fully updated third edition of this popular handbook provides a concise summary of perioperative management of high-risk surgical patients. Written by an international group of senior clinicians, chapters retain the practical nature of previous editions, with concise text in a bulleted format offering rapid access to key facts and advice. Several new chapters cover topics including: anesthetic mortality; cardiopulmonary exercise testing; perioperative optimization; obstructive sleep apnea and obesity hypoventilation syndrome; smoking, alcohol and recreational drug abuse; intraoperative ventilatory management; the role of simulation in managing the high-risk patient; anesthesia, surgery and palliative care; anesthesia and cancer surgery; neurotrauma and other high-risk neuro cases; anesthesia for end-stage renal and liver disease; and transplant patients. Essential reading for trainee anesthesiologists managing seriously ill patients during surgery or studying for postgraduate examinations, this is also a valuable refresher for anesthesiologists and intensivists looking for an update on the latest evidence-based care.

  • Examination Anaesthesia
    La comanda in aproximativ 4 saptamani
    40400lei 350.00 lei

    The updated guide to the Australian and New Zealand College of Anaesthetists final fellowship examination The format of the Australian and New Zealand College of Anaesthetists (ANZCA) final examination has evolved in recent years. This updated exam guide keeps pace with these developments and assists anaesthetic trainees in preparation for the exam. Examination Anaesthesia, 2nd Edition is a comprehensive study guide that focuses solely on the anaesthetic exam, eliminating confusion between this and the intensive care exams. This invaluable medical text itemises all requirements of the Fellow of the Australian and New Zealand College of Anaesthetists (FANZCA) training scheme. Components of the final examination are also detailed, including a breakdown of the marking scheme and recent results. Helpful resources outlined in Examination Anaesthesia, 2nd Edition include new developments on the ANZCA website, textbooks, journals and exam courses along with a broad list of anaesthesia reference and review articles. Trainees will also benefit from separate chapters based on the major components of the written and clinical ANZCA examinations, plus practical strategies for restructuring life around exam preparation.

  • 39400lei 350.00 lei

    This issue of Critical Care Clinics focuses on Mechanical Ventilation and Ventricular Assist Devices, with topics including: Targeted management approach to cardiogenic shock; Prevention and treatment of right heart failure during left ventricular assist device support therapy; Complications of durable left ventricular assist device support therapy; Patient and device management on left ventricular assist device support therapy; Challenges and future directions in left ventricular assist device support therapy; Monitoring global and regional mechanics; Asynchrony consequences and management; Determinants and prevention of ventilator-induced lung injury; Extracorporeal gas exchange; Non-invasive options; Mobilization and VIDD avoidance; Initiating and discontinuing invasive support; and Automation of ventilation.

    ·  Section I: Mechanical Ventilation

    ·  Preface

    ·  Critical Care Airway Management

    ·  Key points

    ·  Introduction

    ·  Complications of urgent endotracheal intubation

    ·  Identification of the difficult airway in urgent endotracheal intubation

    ·  Rapid sequence intubation versus graded sedation intubation for urgent endotracheal intubation

    ·  Direct laryngoscopy versus video laryngoscopy for urgent endotracheal intubation

    ·  Preoxygenation techniques for urgent endotracheal intubation

    ·  Gastric ultrasonography

    ·  Improving the safety of urgent endotracheal intubation

    ·  Summary

    ·  Asynchrony Consequences and Management

    ·  Key points

    ·  Introduction: what is dyssynchrony and why does it matter?

    ·  Dyssynchrony: definitions and mechanistic classification

    ·  Association with poor outcome

    ·  Management

    ·  Summary

    ·  Determinants and Prevention of Ventilator-Induced Lung Injury

    ·  Key points

    ·  Introduction

    ·  Definition of ventilator-induced lung injury

    ·  The nature of ventilator-induced lung injury

    ·  The assessment of ventilator-induced lung injury

    ·  Ventilator-induced lung injury in clinical practice

    ·  How best to prevent ventilator-induced lung injury

    ·  Avoiding Respiratory and Peripheral Muscle Injury During Mechanical Ventilation: Diaphragm-Protective Ventilation and Early Mobilization

    ·  Key points

    ·  Introduction

    ·  Definition and epidemiology

    ·  Clinical significance: impact on outcomes

    ·  Mechanisms of muscle injury and weakness during critical illness

    ·  Prevention and treatment

    ·  Summary

    ·  Automation of Mechanical Ventilation

    ·  Key points

    ·  Introduction

    ·  Definitions

    ·  Proposed advantages

    ·  Automated control of mechanical ventilation

    ·  Adaptive support ventilation

    ·  Summary

    ·  Noninvasive Options

    ·  Key points

    ·  Introduction

    ·  Noninvasive ventilation and continuous positive airway pressure

    ·  Noninvasive ventilation and high-flow nasal cannula oxygenation

    ·  Interfaces of noninvasive ventilation

    ·  Carbon dioxide rebreathing during noninvasive ventilation

    ·  Asynchrony during noninvasive ventilation

    ·  Main indications for noninvasive ventilation

    ·  Other applications of noninvasive ventilation

    ·  Practical advice

    ·  Intensity of inspiratory efforts and lung stretching during noninvasive ventilation

    ·  Summary

    ·  Extracorporeal Gas Exchange

    ·  Key points

    ·  Introduction

    ·  Evidence and indications for mid- to high-flow extracorporeal gas exchange

    ·  Evidence and indications for low flow extracorporeal gas exchange

    ·  Low-flow extracorporeal gas exchange to avoid intubation in acute respiratory failure

    ·  Low-flow extracorporeal gas exchange to facilitate lung-protective ventilation

    ·  Low-flow extracorporeal gas exchange to facilitate weaning

    ·  Actual status and outlook

    ·  Section II: Ventricular Assist Devices

    ·  Preface

    ·  A Targeted Management Approach to Cardiogenic Shock

    ·  Key points

    ·  Introduction

    ·  Etiology

    ·  Pathophysiology

    ·  Evaluation of a patient in cardiogenic shock

    ·  Risk stratification and clinical outcomes

    ·  Treatment

    ·  Summary

    ·  Prevention and Treatment of Right Ventricular Failure During Left Ventricular Assist Device Therapy

    ·  Key points

    ·  Introduction

    ·  Definition of right ventricular failure

    ·  Mechanisms of right ventricular failure

    ·  Prevention of right ventricular failure

    ·  Treatment of right ventricular failure

    ·  Summary

    ·  Device Management and Flow Optimization on Left Ventricular Assist Device Support

    ·  Key points

    ·  Introduction

    ·  Principles of left ventricular assist device function and normal left ventricular assist device physiology

    ·  Power, flow, and pulsatility

    ·  Decreased left ventricular assist device flow

    ·  Increased left ventricular assist device flow

    ·  Ramp study for assessment of device function and speed optimization

    ·  Evidence-based heart failure therapy

    ·  Summary

    ·  Complications of Durable Left Ventricular Assist Device Therapy

    ·  Key points

    ·  Introduction

    ·  Complications related to pump-patient interface

    ·  Complications related to the patient

    ·  Summary

    ·  Challenges and Future Directions in Left Ventricular Assist Device Therapy

    ·  Key points

    ·  Introduction

    ·  Focus on evolving indications

    ·  Focus on patient-centered care and quality of life

    ·  Focus on myocardial recovery and role of concomitant medical therapy

    ·  Focus on risk stratification

    ·  Focus on pulsatility and flow

    ·  Focus on cost-effectiveness of durable left ventricular assist devices

    ·  Focus on minimally invasive implantation techniques

    ·  Focus on durable biventricular support

    ·  Focus on fully implantable systems


  • 39400lei 350.00 lei

    This issue of Critical Care Clinics focuses on Post-intensive Care Syndrome & Chronic Critical Illness, with topics including: Chronic Critical Illness; Chronic Critical Illness and Predicting Outcomes; Persistent Critical Illness; Rehospitalization and Preventing CCI; Measuring Post-Intensive Care Syndrome; Post-Intensive Care Syndrome and teh Role of the ICU Clinician; Frailty and the Association between Long-Term Recovery After ICU; The Role of the Muscles in Post-Intensive Care Syndrome; Intensive Care Nutrition and Post-Intensive Care Recovery; Early mobilization in the ICU to Improve Long Term Recovery; The Use of Sedation in the ICU and Long-Term Outcomes; Cognitive Function after Critical Illness; Anxiety and Depression after ICU; and Family and Support Networks after ICU.

    ·  Section 1: Chronic Critical Illness

    ·  Patient and Population-Level Approaches to Persistent Critical Illness and Prolonged Intensive Care Unit Stays

    ·  Key points

    ·  The epidemiology of long stays in the intensive care unit

    ·  Patient-level differential diagnosis

    ·  Population impact

    ·  Implications of a persistent critical illness framework

    ·  Preventing Chronic Critical Illness and Rehospitalization: A Focus on Sepsis

    ·  Key points

    ·  Introduction

    ·  Medical setbacks and hospital readmission

    ·  Prevention, mitigation, and rehabilitation strategies

    ·  Summary

    ·  Section 2: Post-Intensive Care Syndrome

    ·  Measuring Outcomes After Critical Illness

    ·  Key points

    ·  Introduction

    ·  Outcome domains after critical illness

    ·  Functional status

    ·  Linking diseases with impairments and disabilities

    ·  Summary

    ·  Frailty and the Association Between Long-Term Recovery After Intensive Care Unit Admission

    ·  Key points

    ·  Introduction to frailty

    ·  Pathophysiology of frailty

    ·  Measurement of frailty

    ·  Frailty and critical illness

    ·  Outcomes of frailty in critical illness

    ·  Strategies and interventions

    ·  Addressing knowledge gaps with future work

    ·  Summary

    ·  The Pathophysiology of Neuromuscular Dysfunction in Critical Illness

    ·  Key points

    ·  Introduction

    ·  The condition

    ·  Risk factors

    ·  Mechanisms

    ·  Time frame

    ·  Summary

    ·  Early Mobilization in the Intensive Care Unit to Improve Long-Term Recovery

    ·  Key points

    ·  Introduction

    ·  Summary

    ·  Intensive Care Nutrition and Post–Intensive Care Recovery

    ·  Key points

    ·  Introduction

    ·  To feed or not to feed?

    ·  Is early supplementation of insufficient enteral nutrition with parenteral nutrition beneficial?

    ·  Is early enteral nutrition better than early parenteral nutrition?

    ·  Is early full enteral nutrition beneficial?

    ·  Do high doses of amino acids provide benefit?

    ·  Is indirect calorimetry–based feeding superior to calculation-based feeding?

    ·  Is there a role of adding immunonutrients?

    ·  Mechanisms explaining the absence of a benefit of early full feeding

    ·  Nutrition during recovery and after intensive care unit stay

    ·  Summary

    ·  Sedation, Delirium, and Cognitive Function After Critical Illness

    ·  Key points

    ·  Introduction

    ·  Sedation during critical illness

    ·  Delirium during critical illness

    ·  Cognition after critical illness

    ·  Summary

    ·  Psychiatric Morbidity After Critical Illness

    ·  Key points

    ·  What is meant by psychiatric morbidity?

    ·  How is psychiatric morbidity measured?

    ·  Why is psychiatric morbidity relevant to critical illness?

    ·  How often do critical illness survivors develop psychiatric morbidity?

    ·  Which patient factors are associated with psychiatric morbidity after critical illness?

    ·  What intensive care unit and early postintensive care unit factors are associated with later psychiatric morbidity?

    ·  Which interventions are effective in decreasing postcritical illness psychiatric morbidity?

    ·  What if patients have substantial psychiatric morbidity at follow-up visits?

    ·  Summary

    ·  Family and Support Networks Following Critical Illness

    ·  Key points

    ·  Introduction

    ·  Psychosocial outcomes of informal caregivers across the care arc

    ·  Outcome measurement

    ·  Interventional research to improve caregiver psychosocial outcomes

    ·  Innovative approaches to rapidly build social support networks


  • 42000lei 360.00 lei

    Encompassing all anesthesia topics from basic to advanced, Miller's Anesthesia Review, 3rd Edition, by Drs. Lorraine M. Sdrales and Ronald D. Miller, is an ideal study guide to assess your knowledge and deepen your understanding. This easy-to-use resource is conveniently cross-referenced to the newest edition of Miller & Pardo: Basics of Anesthesia. Hundreds of questions cover everything from physiologic and pharmacologic principles through anesthetic machine systems, anesthetic delivery in a variety of settings, and anesthesia administration for a full range of disease states. Corresponds to Miller & Pardo's Basics of Anesthesia to help you make the most of your study time and learn more efficiently. Provides immediate feedback with detailed answers to each question at the end of every chapter, cross-referenced to specific pages in Basics of Anesthesia. Includes new chapters on Neurotoxicity of Anesthesia, Palliative Care, Sleep Medicine, and Perioperative Surgical Home. Brings you fully up to date with revised questions throughout, progressing logically from basic to advanced topics. Covers hot topics such as Implantable Cardiac Pulse Generators, Anesthesia for Robotic Surgery, Perioperative Blindness, Human Performance and Patient Safety, and Civil, Chemical, and Biological Warfare. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

  • Kaplan s Essentials of Cardiac Anesthesia
    La comanda in aproximativ 4 saptamani
    42000lei 380.00 lei

    Authored by the same stellar editors and contributors responsible for Kaplan's Cardiac Anesthesia, this title presents today's most essential clinical knowledge in cardiac anesthesia in a practical, user-friendly format. A manageable size and affordable price makes this an ideal purchase for every clinician who would like an economical yet dependable resource in cardiac anesthesia. Trusted authorities deliver the key cardiac anesthesia knowledge you need to know. A concise, user-friendly format and key points boxes in each chapter help you quickly locate crucial information. Annotated references guide you to the most practical additional resources. A portable size and clinical emphasis facilitates and enhances bedside patient care. Designed as a companion to Kaplan's Cardiac Anesthesia. Includes new topics vital to the current practice of cardiac anesthesiologists, such as transesophageal echocardiography; percutaneous valve procedures; new pacemakers and automatic internal defibrillators used for cardiac resynchronization therapy; left ventricular assist devices and extracorporeal membrane oxygenation therapy of heart failure; and patient safety issues. Focuses on today's most current and relevant therapies, including New Cardiac Drugs, and Heart Mate, Heart Ware, and Impella LVADs. Describes care of the cardiac patient in Hybrid Operating Rooms, Catheterization Laboratories, and Electrophysiology Laboratories, as well as the Cardiac Operating Rooms. Perfectly suited for residents, fellows, nurse anesthetists and anesthesiologists in practice.

  • 42000lei 380.00 lei

    Practical Ambulatory Anesthesia covers all aspects of sedation, anesthesia, and pain relief for patients undergoing day (ambulatory) surgery. Written and edited by leading clinical anesthesiologists from the USA and Europe, it provides clear guidance on how to handle particular patients in particular situations. Comprehensive in scope, each chapter summarizes major studies and review papers, followed by practical advice based on the authors' and editors' clinical and scientific expertise. This combination of authoritative evidence-based guidance and personal advice ensures the reader benefits from the latest scientific knowledge and the authors' wealth of experience. Chapters discuss how to plan, equip and staff an ambulatory unit, pharmacology, key concepts of ambulatory care, pre- and post-operative issues, quality assurance, and current controversies. There are also dedicated chapters for topics including regional anesthesia for ambulatory surgery and pediatric ambulatory anesthesia. This text provides a much-needed comprehensive and evidence-based guide for clinical anesthesiologists

  • Basics of Anesthesia, 7e
    La comanda in aproximativ 4 saptamani
    42000lei 400.00 lei

    The undisputed leading text in its market, Basics of Anesthesia, 7th Edition, provides comprehensive coverage of both basic science and clinical topics in anesthesiology. Drs. Manuel C. Pardo, Jr. and Ronald D. Miller, in conjunction with many new contributors, have ensured that all chapters are thoroughly up to date and reflect the latest advances in today's practice. Unparalleled authorship, concise text, easy-to-read chapters, and a user-friendly format make this text the #1 primer on the scope and practice of anesthesiology. Presents the combined expertise of two of the most prolific and renowned anesthesia experts worldwide, along with more than 80 expert contributing authors. Uses a concise, at-a-glance format to cover both the basic science and essential clinical aspects of the field, including pathophysiology, pharmacology, regional anesthesia, anesthetic management, and special problems and patient groups. Features high-quality images that offer a detailed visual understanding of regional anesthesiology and much more. Includes new topics and chapters on Neurotoxicity of Anesthesia, Palliative Care, Sleep Medicine, Perioperative Surgical Home, Trauma, and Natural/Human-Induced Disasters. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

  • 47300lei 405.00 lei

     

    Description:

    Offering complete, up-to-date coverage of everything from basic science through current clinical practice, Hall Anesthesia: A Comprehensive Review, 6th Edition, provides 1,000 review questions that help you improve your mastery of anesthesiology. You’ll reinforce your current knowledge, identify areas that require more study, and improve your long-term retention of the material – all while preparing for certification and re-certification examinations as well as clinical practice.

    • Provides 1,000 completely updated review questions (more than 100 are brand-new) with explanations in the answers. Every question has been reviewed by at least one additional author and vetted by Mayo residents to ensure a consistent level of difficulty.
    • Familiarizes you with the current ABA exam content and format, with challenging board review questions and answers covering the latest discoveries and techniques in physics, biochemistry, and anesthesia equipment; the newest drugs and drug categories; and the most recent information on all anesthesia subspecialties.
    • Offers discussions after each question, along with corresponding page references to major anesthesia texts so it’s easy to find more information on any subject.

     

    Table of Contents:

     

    1.    Part 1: Basic Sciences

    2.    Chapter 1: Anesthesia Equipment and Physics

    3.    Anesthesia Equipment and Physics

    4.    Chapter 2: Respiratory Physiology and Critical Care Medicine

    5.    Respiratory Physiology and Critical Care Medicine

    6.    Chapter 3: Pharmacology and Pharmacokinetics of Intravenous Drugs

    7.    Abstract

    8.    Pharmacology and Pharmacokinetics of Intravenous Drugs

    9.    Chapter 4: Pharmacology and Pharmacokinetics of Volatile Anesthetics

    10.  Pharmacology and Pharmacokinetics of Volatile Anesthetics

    11.  Part 2: Clinical Sciences

    12.  Chapter 5: Blood Products, Transfusion, and Fluid Therapy

    13.  Blood Products, Transfusion, and Fluid Therapy

    14.  Chapter 6: General Anesthesia

    15.  General Anesthesia

    16.  Chapter 7: Pediatric Physiology and Anesthesia

    17.  Abstract

    18.  Pediatric Physiology and Anesthesia

    19.  Chapter 8: Obstetric Physiology and Anesthesia

    20.  Obstetric Physiology and Anesthesia

    21.  Chapter 9: Neurologic Physiology and Anesthesia

    22.  Neurologic Physiology and Anesthesia

    23.  Chapter 10: Anatomy, Regional Anesthesia, and Pain Management

    24.  Abstract

    25.  Anatomy, Regional Anesthesia, and Pain Management

    26.  Chapter 11: Cardiovascular Physiology and Anesthesia

    27.  Cardiovascular Physiology and Anesthesia

    28.  Index

     

  • 44000lei 410.00 lei

    Get a quick, expert overview of the many key facets of neuropathic pain syndromes with this concise, practical resource by Drs. Mitchell Freedman, Jeff Gehret, George Young, and Leonard Kamen. This easy-to-read reference presents a summary of today's best evaluation methods and evidence-based treatment options for complex regional pain syndrome as well as other challenging syndromes. Covers key topics such as: Evidence Based Approach to Many Uncommon and Difficult Neuropathic Pain Syndromes Review of Pathophysiology of Pain Approach to Chronic Pain Syndromes Work Up and Treatments for Complex Regional Pain Syndromes Consolidates today's available information and experience in this multifaceted area into one convenient resource.

  • 52000lei 420.00 lei

     Written and edited by experts in the field, the Handbook of Clinical Anaesthesia provides all the essential practical knowledge required by anaesthetists on co-existing medical conditions, operative procedures, and techniques. The fourth edition retains the concise and comprehensive nature of the third, giving readers all they need to know about each part of the FRCA syllabus in short, digestible, practical entries.

     

    The first part covers Patient Conditions; the second Surgical Procedures; and the third Anaesthetic Factors. Each part is subdivided into chapter on each organ system, and each chapter is divided into bite-sized entries. These are in alphabetical order, and cover all common and rare conditions that anaesthetists will encounter within their practice. Avoiding prolonged discussion and multiple references, this is the ideal book to ‘dip into’ either for specific advice or general education, providing quick and reliable information. 

     

    This is the most thorough handbook to cover the entire FRCA syllabus in a consistent and instructive manner. It continues to be accessible and relevant to all anaesthetists from middle grade trainee up to consultant/specialist.

  • A Practical Approach to Pediatric Anesthesia
    La comanda in aproximativ 4 saptamani
    50000lei 420.00 lei

    Part of the highly popular Practical Approach to Anesthesia series, this new edition combines the comprehensive depth of a textbook and the user-friendly features of a practical handbook. Focusing on clinical issues in pediatric anesthesia, it contains the in-depth information you need for daily practice and study, presented in a concise, bulleted format for quick reference. With its emphasis on developmental aspects of pediatric anesthesia, numerous illustrations and tables, and methodical approach to decision making, this updated reference is an invaluable resource for anyone involved with anesthesia of children. Key Features * Features new chapters on vascular biology and vascular anomalies, healing and recovery in pediatric surgery, and training and education in pediatric anesthesia. All existing chapters have been fully updated to keep you up to date.* Covers key issues of growth and development - anatomic, physiologic, and pharmacologic - that form the basis for a better understanding of pediatric anesthesia.* Discusses the approach to the pediatric patient, clinical and operational aspects of pediatric anesthesia, anesthetic management of normalities and abnormalities of each organ system, and special situations such as fetal surgery, anesthesia outside the operating room, and trauma.* Provides a clear understanding of anomalies, embryology, anatomy, and surgery so that you're well prepared to choose the best induction, maintenance, and emergence techniques, as well as make informed monitoring and equipment decisions.* Presents information in a bulleted, outline format for easy reference and review.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:*Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

  • 46000lei 430.00 lei

    Apply the latest advances in regional anesthesia and acute pain medicine! Originally authored by Michael F. Mulroy, MD, this respected title has helped practitioners provide effective regional anesthesia for nearly 30 years. Now it has been retitled A Practical Approach to Regional Anesthesiology and Acute Pain Medicine to reflect the Accreditation Council for Graduate Medical Education's recent establishment of Regional Anesthesiology and Acute Pain Medicine as an anesthesiology fellowship. This clinical reference has evolved with the many changes in this subspecialty to continue bringing you the up-to-date, clinically focused, hands-on guidance you need to offer your patients the best possible care. Master the latest advances in the field with expanded coverage of truncal blocks, systems-based practice, acute pain medicine, and much more.Make optimal use of ultrasound guidance as a nerve localization tool for peripheral nerve blocks, thanks to updated and expanded coverage as well as many new and improved illustrations.The techniques, approaches, and systems-based practices covered in 5th edition will enhance the application and role of regional anesthesia in Enhanced Recovery After Surgery (ERAS) pathways and the perioperative surgical home. Easily find and apply the answers you need thanks to a highly readable, focused, richly illustrated format that provides balanced discussions of indications, complications, and techniques.Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offlinePowerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooksMultiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive designThe ability to highlight text and add notes with one clickSee the inside front cover to find out how to access your eBook!

  • 45800lei 430.00 lei

    Approach any critical care challenge using a practical, consistent strategy based on best practices with Evidence-Based Practice of Critical Care, 3rd Edition. Unique, question-based chapters cover the wide variety of clinical options in critical care, examine the relevant research, and provide recommendations based on a thorough analysis of available evidence. Drs. Clifford S. Deutschman and Patrick J. Nelligan, along with nearly 200 critical-care experts, provide a comprehensive framework for translating evidence into practice, helping both residents and practitioners obtain the best possible outcomes for critically ill patients. Covers a full range of critical care challenges, from routine care to complicated and special situations. Helps you think through each question in a logical, efficient manner, using a practical, consistent approach to available management options and guidelines. Features revised and updated information based on current research, and includes all-new cases on key topics and controversies such as the use/overuse of antibiotics, drug resistance in the ICU, non-invasive mechanical ventilation, frequency of transfusions, and duration of renal replacement therapies. Provides numerous quick-reference tables that summarize the available literature and recommended clinical approaches. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

  • 58700lei 470.00 lei

     

    Description:

    This highly successful textbook is internationally renowned as a core text for trainee anaesthetists and is essential reading for candidates for the Fellowship of Royal College of Anaesthetists and similar examinations. The previous 6th edition was awarded First Prize at the BMJ Medical Book awards.

    The book provides full coverage of the sciences underpinning practice in anaesthesia, critical care and pain management together with details of clinical anaesthesia and perioperative care. In combining these aspects, anaesthetists new to the specialty have found the textbook particularly useful during the first few years of training as well as when preparing for professional examinations. It has also proved a valuable day-to-day reference for allied professionals such as operating department practitioners and physician assistants who need an understanding of clinical practice in anaesthesia and related specialties.

    The goal for this Seventh Edition has remained to equip the reader with the basic knowledge and practical considerations required to administer anaesthesia and perioperative care for a whole range of surgical conditions in patients with all common medical comorbidities. Reflecting the expanding role of anaesthesia beyond the operating theatre it also includes essential material related to safety and quality assurance, consent, resuscitation, intensive care medicine, pre-hospital care and chronic pain management.

    • This book’s scope includes the full range of clinical practice, from anaesthetic equipment and pre-operative assessment through to post-operative care, local anaesthesia, anaesthesia for individual specialties and the management of chronic pain.
    • The text covers the principles of pharmacology, anaesthetic agents and physics for the anaesthetist.
    • Thirty new contributors provide a new perspective or contribute new chapters to this edition
    • This edition has been restructured into four sections: Basic Sciences; Physics and Apparatus; Fundamentals of Anaesthesia and Perioperative Medicine; and Clinical Anaesthesia.
    • Four new chapters have been added, both to reflect the UK postgraduate anaesthetic examination syllabus and changes in clinical practice. There are: The older patient; Anaesthesia in low and middle-income areas; Management of critical incidents; and Data analysis, clinical trials and statistics.
    • This edition makes extensive use of new line drawings and diagrams and, for the first time, many of these are available in colour.
    • Chapters have been extensively cross-referenced to aid the reader and avoid repetition to include substantially more information without increasing the overall size of the book.

     

    Table of Contents:

     

    1.    Section 1 Basic sciences

    2.    Chapter 1 General principles of pharmacology

    3.    Basic principles

    4.    How do drugs act?

    5.    How does the body process drugs (pharmacokinetics)?

    6.    Pharmacokinetic principles

    7.    Pharmacological variability

    8.    Pharmacogenetics

    9.    Drug interactions and adverse drug effects

    10.  Self-assessment questions and answers

    11.  Answer 1

    12.  Question 2

    13.  Answer 2

    14.  Question 3

    15.  Answer 3

    16.  Question 4

    17.  Answer 4

    18.  Chapter 2 Data, statistics and clinical trials

    19.  Types of data

    20.  Summarising data

    21.  Sampling

    22.  Probability

    23.  Data distributions

    24.  Bias

    25.  Testing

    26.  Predictive testing and scoring systems

    27.  Types of error

    28.  Bayesian statistics

    29.  Clinical trials

    30.  Specific aspects of trial conduct

    31.  Evidence-based medicine

    32.  Audit, research and service evaluation

    33.  References/Further reading

    34.  Self-assessment questions and answers

    35.  Chapter 3 Inhalational anaesthetic agents and medical gases

    36.  Kinetics of inhaled anaesthetic agents

    37.  Mechanism of action

    38.  Minimum alveolar concentration

    39.  Pharmacokinetics of inhaled anaesthetic agents

    40.  Individual anaesthetic agents

    41.  Medical gases

    42.  Self-assessment questions and answers

    43.  Answer 1

    44.  Question 2

    45.  Answer 2

    46.  Question 3

    47.  Answer 3

    48.  Chapter 4 Intravenous anaesthetic agents and sedatives

    49.  Intravenous anaesthetic drugs

    50.  Mechanism of action

    51.  Pharmacokinetics

    52.  Offset of hypnotic effect

    53.  Precautions when using i.v. anaesthetics

    54.  Pharmacology of individual intravenous anaesthetic drugs

    55.  Maintenance of anaesthesia using i.v. agents

    56.  Practical techniques for i.v. maintenance of anaesthesia

    57.  Sedative and anxiolytic drugs

    58.  Drugs used as sedatives

    59.  Non-benzodiazepine hypnotics (Z-drugs)

    60.  α2-Adrenoceptor agonists

    61.  Opioids

    62.  Antipsychotics

    63.  Miscellaneous

    64.  References/Further reading

    65.  Self-assessment questions and answers

    66.  Answer 1

    67.  Question 2

    68.  Answer 2

    69.  Question 3

    70.  Answer 3

    71.  Question 4

    72.  Answers 4

    73.  Question 5

    74.  Answers 5

    75.  Chapter 5 Local anaesthetic agents

    76.  Mechanism of action of local anaesthetics

    77.  The voltage-activated Na+ channel

    78.  Pain fibres

    79.  Local anaesthetic structure

    80.  Pharmacological properties of local anaesthetics

    81.  Differential sensory and motor blockade

    82.  Pharmacokinetics

    83.  Clinical preparation of local anaesthetics

    84.  Enantiomer pharmacology

    85.  Pharmacology of individual local anaesthetics

    86.  Local anaesthetic toxicity

    87.  Management of severe local anaesthetic toxicity

    88.  Self-assessment questions and answers

    89.  Answer 1

    90.  Question 2

    91.  Answer 2

    92.  Question 3

    93.  Answer 3

    94.  Question 4

    95.  Answer 4

    96.  Chapter 6 Physiology and pharmacology of pain

    97.  Mechanisms of pain

    98.  Pharmacology of analgesic drugs

    99.  Opioids

    100.               Mixed agonist–antagonist opioids

    101.               Partial agonists

    102.               Opioid antagonists

    103.               New developments in opioid pharmacology

    104.               Paracetamol

    105.               Non-steroidal anti-inflammatory drugs (NSAIDs)

    106.               COX-2–specific inhibitors

    107.               Conclusion

    108.               References/Further reading

    109.               Self-assessment questions and answers

    110.               Chapter 7 Postoperative nausea and vomiting

    111.               Definitions

    112.               Mechanisms of nausea and vomiting

    113.               Adverse effects of PONV

    114.               Identifying patients at risk

    115.               Pharmacology

    116.               Management

    117.               References/Further reading

    118.               Self-assessment questions and answers

    119.               Chapter 8 Muscle function and neuromuscular blockade

    120.               Physiology of neuromuscular transmission

    121.               Pharmacology of neuromuscular transmission

    122.               Depolarising neuromuscular blocking agents

    123.               Reversal agents

    124.               Neuromuscular monitoring

    125.               References/Further reading

    126.               Self-assessment questions and answers

    127.               Chapter 9 Cardiovascular system

    128.               Cardiovascular physiology

    129.               Cardiovascular pharmacology

    130.               References/Further reading

    131.               Self-assessment questions and answers

    132.               Chapter 10 Respiratory system

    133.               Control of breathing

    134.               Respiratory system mechanics

    135.               Pulmonary circulation

    136.               Regional ventilation and perfusion

    137.               Oxygen and carbon dioxide transport

    138.               Respiratory effects of general anaesthesia

    139.               Positive pressure ventilation

    140.               Respiratory physiology at high altitude

    141.               Self-assessment questions and answers

    142.               Chapter 11 Renal physiology

    143.               Renal anatomy

    144.               Glomerular anatomy, filtration and tubular feedback

    145.               Renin–angiotensin–aldosterone system and vasopressin

    146.               Pharmacology of drugs acting on the kidney

    147.               Assessment of renal function

    148.               Acute kidney injury and contrast nephropathy

    149.               Intrinsic renal injury

    150.               References/Further reading

    151.               Self-assessment questions and answers

    152.               Chapter 12 Fluid, electrolyte and acid–base balance

    153.               Physiology of electrolytes and water balance

    154.               Basic definitions

    155.               Compartmental distribution of total body water

    156.               Solute composition of body fluid compartments

    157.               Water homeostasis

    158.               Practical fluid balance

    159.               Sodium, potassium, chloride, phosphate and magnesium

    160.               Acid–base balance

    161.               Self-assessment questions and answers

    162.               Answer 1

    163.               Chapter 13 Metabolism, the stress response to surgery and perioperative thermoregulation

    164.               Metabolism

    165.               Carbohydrates

    166.               Proteins

    167.               Lipids

    168.               Basic nutritional requirements

    169.               Starvation

    170.               The effects of chronic malnutrition on anaesthesia

    171.               The stress response to surgery

    172.               Thermoregulation and anaesthesia

    173.               References/Further reading

    174.               Self-assessment questions and answers

    175.               Answer 1

    176.               Question 2

    177.               Answer 2

    178.               Question 3

    179.               Answer 3

    180.               Question 4

    181.               Answer 4

    182.               Question 5

    183.               Answer 5

    184.               Chapter 14 Blood, coagulation and transfusion

    185.               The physiology of blood

    186.               Interventional procedures and regional anaesthesia in coagulopathic patients

    187.               Thrombosis and acute ischaemic events

    188.               Blood products and blood transfusion

    189.               Major haemorrhage and massive transfusion protocols

    190.               References/Further reading

    191.               Self-assessment questions and answers

    192.               Answer 1

    193.               Question 2

    194.               Answer 2

    195.               Question 3

    196.               Answer 3

    197.               Question 4

    198.               Answer 4

    199.               Section 2 Physics and apparatus

    200.               Chapter 15 Basic physics for the anaesthetist

    201.               Basic definitions

    202.               Basic mathematical functions

    203.               Fluids

    204.               Gas regulators

    205.               The Venturi, the injector and Bernoulli

    206.               Heat

    207.               Vaporisation

    208.               Humidity and humidification

    209.               Solubility of gases

    210.               Electricity

    211.               Electrical safety

    212.               Radiation

    213.               Magnetic resonance imaging

    214.               Ultrasound

    215.               Lasers

    216.               Optical fibres

    217.               Fires and explosions

    218.               References/Further reading

    219.               Self-assessment questions and answers

    220.               Chapter 16 Anaesthetic apparatus

    221.               Gas supplies

    222.               Cylinders

    223.               The anaesthetic machine

    224.               Safety features of modern anaesthetic machines

    225.               Breathing systems

    226.               Ventilators

    227.               Scavenging

    228.               Reservoir bags