Critical Care of the Solid Organ Transplant Patient, An Issue of Critical Care Clinics, Volume 35-1

Description:

This issue of Critical Care Clinics, Guest Edited by Dr. Kenneth McCurry and Dr. Ali Al-Khafaji, focuses on Critical Care of the Solid Organ Transplant Patient. Dr. McCurry’s section of the issue is devoted to Heart and Lung Transplants and includes the following topics: Long term outcomes of transplantation; Mechanical ventilation; Pulmonary hypertension therapy; Extracorporeal membrane oxygenation; Perioperative management of the lung graft following lung transplantation; Perioperative management of the heart graft following heart transplantation; Renal complications following lung and heart transplantation; and Infection and other complications following transplanation. Dr. Al-Khafaji’s section of the issue is devoted to Liver, Kidney, and Small Bowel Transplants and includes the following topics: The immediate postoperative period; Live donor liver transplant; Graft dysfunction and management; Extracorporeal devices; Infectious complication following solid organ transplants; and Cardiac, renal, neurological, and gastrointestinal complications.

·  Section I: Heart & Lung

·  Preface

·  Brief Overview of Lung, Heart, and Heart-Lung Transplantation

·  Key points

·  Introduction

·  Historical aspects of development of cardiothoracic transplantation and current trends

·  Recipient selection and outcomes

·  Immunosuppression

·  Summary

·  Bridging to Lung Transplantation

·  Key points

·  Introduction

·  Summary/discussion

·  Summary

·  Perioperative Management of the Lung Graft Following Lung Transplantation

·  Key points

·  Introduction

·  Primary graft dysfunction

·  Ventilatory strategies of the transplanted lungs

·  Hemodynamic management in the perioperative period

·  Perioperative fluid administration and cardiac output management

·  Postoperative considerations unique to patients with lung transplantation

·  Perioperative considerations in patients with different underlying disease presenting for lung transplantation

·  Gaps of knowledge and future directions in the perioperative care of the lung transplant patient

·  Perioperative Management of the Cardiac Transplant Recipient

·  Key points

·  Introduction

·  Hemodynamic monitoring

·  Coagulopathy, bleeding, and product administration

·  Vasoplegia

·  Inotropic and chronotropic support

·  Right ventricular failure and pulmonary hypertension

·  Arrhythmia

·  Ventilator support

·  Renal and volume status

·  Management of primary graft dysfunction

·  Renal Complications Following Lung Transplantation and Heart Transplantation

·  Key points

·  Introduction

·  Epidemiology, risk factors, and pathogenesis

·  Impact of renal failure

·  Diagnosis and management

·  Management of chronic renal impairment

·  Kidney transplantation after heart or lung transplantation

·  Summary

·  Infections in Heart and Lung Transplant Recipients

·  Key points

·  Introduction

·  Epidemiology

·  Risk factors

·  Specific clinical syndromes

·  Opportunistic infections

·  Section II: Liver, Kidney, and Small Bowel

·  Preface

·  Perioperative Management of the Liver Transplant Recipient

·  Key points

·  Overview

·  Process

·  Candidate selection: too sick for transplant?

·  Goals of care

·  Postoperative management

·  Hemodynamics

·  Neurologic

·  Respiratory

·  Renal

·  Gastrointestinal and nutrition

·  Infection

·  Hematologic considerations

·  Rehabilitation

·  Summary

·  Critical Care Management of Living Donor Liver Transplants

·  Key points

·  Introduction

·  The surgical procedure

·  The donor

·  The recipient

·  Summary

·  Graft Dysfunction and Management in Liver Transplantation

·  Key points

·  Introduction

·  Vascular issues

·  Primary nonfunction (and primary graft dysfunction)

·  Rejection

·  Post–liver transplant cholestasis

·  Intrahepatic cholestasis

·  Extrahepatic cholestasis

·  Donor factors affecting graft function

·  Extracorporeal Devices

·  Key points

·  Introduction

·  Critical care rational for extracorporeal liver support devices

·  Extracorporeal liver support systems

·  Bioartificial extracorporeal liver support in acute liver failure

·  Summary and challenges

·  Infectious Complications Following Solid Organ Transplantation

·  Key points

·  Introduction

·  Bloodstream infections/sepsis

·  Respiratory tract infections

·  Neurologic infections

·  Hepatobiliary infections

·  Enterocolitis

·  Genitourinary infections

·  Summary

·  Complications of Solid Organ Transplantation: Cardiovascular, Neurologic, Renal, and Gastrointestinal

·  Key points

·  Background

·  Cardiovascular complications

·  Neurologic complications after solid organ transplantation

·  Renal complications after solid organ transplantation

·  Gastrointestinal complications after solid organ transplantation