pe pagina
  • 68.00 lei

    We have all experienced itch, whether from insect bites or dry skin, but millions of people worldwide have chronic or even intractable itch. Just like chronic pain, chronic itch interferes with function – even with quality of life. "Living with Itch" offers relief, drawing on the authors' vast knowledge of itch, the suffering it causes, and available treatments. Itch researchers and clinicians Drs. Gil Yosipovitch and Shawn G. Kwatra explain what itch is and the cascade of physiological events that cause us to experience it. They describe the many skin diseases, from atopic dermatitis (also known as eczema) to psoriasis, and conditions like chronic kidney disease, lymphoma, HIV, and neuropathies that cause itch. "Living with Itch" provides information on preventing itch as well as topical and systemic therapies, regardless of what's causing the itch. Patient and parent narratives explain how itch affects their lives and how they cope with a symptom that can, with medical and social support, be managed.

  • 132.00 lei

    This book represents a new and hopeful paradigm for treatment of diseases that are spreading globally as countries adopt Western lifestyles and standards of living. It describes the phenomenal science and clinical efficacy of the work of Dr Xiu-Min Li across a broad array of immune and inflammatory diseases. These include food allergies, asthma, eczema, "new" diseases such as mast cell disorders, obesity, and mental health problems that are part of a worldwide "epidemic of progress". The most allergic people are caught in a cycle of medication, steroid dependency, emergency hospitalization, and curtailing their activities and diets to avoid triggers. Children are "losing their childhoods." They are fighting a battle against diet, climate change, and environmental degradation. Dr Li offers them hope by healing the entire immune system, not just address symptoms. In her practice Dr Li treats complex combinations of allergic diseases for all ages, from infancy through adulthood, bringing relief to people who have suffered terribly from oozing, bleeding skin, desperate breathing disorders, and life-threatening food allergies. She uses her vast knowledge of biochemistry to improve on the traditional decoctions to create refined versions suitable for modern tastes and lifestyles. In contrast with Western pharmaceuticals, which are the study of "one molecule's effects on one other molecule" Dr Li's work shows the effects of multiple molecules on multiple other molecules. Increasing numbers of scientists are beginning to see the possibilities for their own research, with the prospects for more collaborations with prestigious institutions around the world.

  • 138.00 lei

    Systematic lupus erythematosus is an autoimmune disease that can affect any system and organ in the body. For the 1.4 million people in the United States who have lupus, their overactive immune system senses that different parts of the body do not belong

  • 144.00 lei

    Posing the questions that anyone with food allergies will think to ask – and then some – "Food Allergies" provides practical, emotional, and scientific guidance on the topics that affect your life. Allergy expert Scott H. Sicherer addresses the full spectrum of food allergies, from mild to life threatening, from single foods to food families, clearing up misconceptions along the way. He explains how exposure to foods can bring about an allergic response, describes the symptoms of food allergy, and illuminates how food allergies develop. He also recommends tests for diagnosing both food allergies and chronic health problems caused by food allergies – such as eczema, hives, and respiratory and gastrointestinal symptoms. "Food Allergies" thoroughly explains how to prevent exposure to a known allergen at home, at school, in restaurants, and elsewhere and what to do if exposure occurs, including how to handle an anaphylactic emergency. Dr. Sicherer also reviews food reactions that are not allergic (such as lactose intolerance), advises how to get adequate nutrition when you must avoid dietary staples, and discusses whether allergies ever go away (they do – and then sometimes they return).

  • 160.00 lei

    Lippincott's Illustrated Reviews: Immunology offers a highly visual presentation of essential immunology material, with all the popular features of the series: more than 300 full-color annotated illustrations, an outline format, chapter summaries, review questions, and case studies that link basic science to real-life clinical situations. Lippincott's Illustrated Reviews: Immunology can be used as a review text for a short immunology course, or paired with Lippincott's Illustrated Reviews: Microbiology for a combined microbiology/immunology course.

  • 18500lei 165.00 lei

    Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible. The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Clinical Immunology gives the new biomedical scientist an insight into the function of the immune system, the front line of defence against pathological disease, and the diagnostic techniques used to identify associated malfunctions and disorders. By examining the key immunological principles and scientific basis of laboratory techniques with a focus on the biomedical scientist's role in the diagnostic laboratory, the reader is provided with everything needed to prepare for a specialist qualification in immunology. Current tests, the rationale behind their use, the technologies employed, and the quality measures applied are illustrated by specific case studies showing how the clinician interprets the results to help the patient. Online Resource Centre The Online Resource Centre to accompany Clinical Immunology features: For registered adopters of the book: - Figures from the book, available to download For students: - Answers to self-check and end of chapter questions - Video podcasts including interviews with practicing biomedical scientists and 'in the lab' footage showing biomedical science in practice

  • 185.00 lei

    The Oxford Handbook of Clinical Immunology and Allergy is a unique, practical and clinically relevant guide for clinicians and laboratory staff to assist with the diagnosis and management of immunological/allergic disease, and the correct selection and interpretation of immunological tests. Now fully updated for the third edition, the handbook has been expanded to include the latest developments, drugs, diagnostic tests, and therapy options in the field. 

    With concise, bullet-point coverage of the entire breadth of immunological and allergic disease, this handbook has been specially written to ensure the information you need is always at your fingertips. The first section covers clinical diseases, giving guidance on test selection and interpretation for both diagnosis and monitoring. The second section covers diagnostic tests, summarizing the methodology and pros and cons of each. Expertly written, reviewed by specialists, and fully up-to-date, you can be sure that the Oxford Handbook of Clinical Immunology and Allergy provides all the vital information you will need to assist you in effective practice.

  • 210.00 lei

    Un panorama complet et abordable des concepts essentiels de l'immunologie ! Grâce à une présentation synthétique et claire des principes clés du fonctionnement du système immunitaire, ce manuel vous accompagne dans l'assimilation des bases de l'immunologie moderne. Cette 5e édition intègre les avancées les plus récentes dans la compréhension du système immunitaire et leurs applications cliniques pour le traitement des maladies associées à ses dérégulations, notamment l'immunothérapie du cancer, qui connaît un développement remarquable. Une édition indispensable aux étudiants : les différents types de mécanismes qui déclenchent et gouvernent les réponses immunitaires ; 200 illustrations en couleurs ; des cas cliniques détaillés pour mieux comprendre l'application des principes aux maladies les plus communes ; des résumés des points clés de chaque chapitre ; un contrôle des connaissances à la fin de chaque chapitre vous offre la possibilité de vous tester ; en annexe, un récapitulatif présente les familles et structures moléculaires, les fonctions connues ou supposées, les effets biologiques, et autres spécificités des différentes cytokines et des molécules CD traitées dans l'ouvrage ; un glossaire des termes techniques en français et en anglais.

  • Immunology: A Short Course
    La comanda in aprox. 4 saptamani
    24800lei 223.00 lei

    A Short Course, 7th Edition introduces all the critical topics of modern immunology in a clear and succinct yet comprehensive fashion. The authors offer uniquely–balanced coverage of classical and contemporary approaches and basic and clinical aspects. The strength of Immunology: A Short Course is in providing a complete review of modern immunology without the burden of excessive data or theoretical discussions. Each chapter is divided into short, self–contained units that address key topics, illustrated by uniformly drawn, full–color illustrations and photographs. This new edition of Immunology: A Short Course: Has been fully revised and updated, with a brand new art program to help reinforce learning Includes a new chapter on Innate Immunity to reflect the growth in knowledge in this area Highlights important therapeutic successes resulting from targeted antibody therapies Includes end of chapter summaries and review questions, a companion website at featuring interactive flashcards, USMLE–style interactive MCQs, figures as PowerPoint slides, and case–based material to help understand clinical applications

  • 29500lei 265.00 lei

    Review of Medical Microbiology and Immunology is a succinct, high-yield review of the medically important aspects of microbiology and immunology. It covers both the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology and also discusses important infectious diseases using an organ system approach. The book emphasizes the real-world clinical application of microbiology and immunology to infectious diseases and offers a unique mix of narrative text, color images, tables and figures, Q&A, and clinical vignettes. Content valuable to any study objective or learning style: · 650 USMLE-style practice questions test your knowledge and understanding · 50 clinical cases illustrate the importance of basic science information in clinical diagnosis · A complete USMLE-style practice exam consisting of 80 questions helps you prepare for the exam · Pearls impart important basic science information helpful in answering questions on the USMLE · Concise summaries of medically important organisms · Self-assessment questions with answers appear at the end of each chapter · Color images depict clinically important findings, such as infectious disease lesions · Gram stains of bacteria, electron micrographs of viruses, and microscopic images depict fungi, protozoa, and worms · Chapters on infectious diseases from an organ system perspective Sections Include: Basic Bacteriology, Clinical Bacteriology, Basic Virology, Clinical Virology, Mycology, Parasitology, Immunology, Ectoparasites, Infectious Diseases, Brief Summaries of Medically Important Organisms, Clinical Cases, Pearls for the USMLE, USMLE Practice Questions, USMLE Practice Examination.

  • 29600lei 265.00 lei

    This third edition of the essential guide has been extensively revised and updated and includes additional color illustrations. It reflects the rapid expansion in knowledge of the subject due to progress in the chemical, immunological, and clinical fields.

  • 33600lei 300.00 lei

    This book is a quick guide for clinicians, specialists, and residents. It provides a concise overview of the practical aspects of contact dermatitis, supplying the tools to allow a fast and reliable diagnosis. The book describes the clinical features of contact dermatitis, explains how to make an exposure assessment and covers other essentials in the diagnostic work. Information is presented on testing with patients’ own products and overviews are provided on the allergens contained in various products. In addition, a helpful list of the most frequent allergens is included. The authors are leading practitioners in the field, and their expertise has enabled the compilation of an approachable text supplemented by a large number of full color illustrations, tables and check lists. This book will help the reader to gain a better understanding of the subject and to achieve greater competence in everyday practice.

  • 34500lei 315.00 lei

    The top required and recommended immunology text worldwide, Cellular and Molecular Immunology by Drs. Abul K. Abbas, Andrew H. H. Lichtman, and Shiv Pillai, is a clear, well-written, and superbly illustrated introduction to the field. The 9th Edition retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging information in this challenging area. Highlights the implications of immunologic science for the management of human disease, emphasizing clinical relevance throughout. Provides a highly visual, full-color description of the key immunologic and molecular processes with a fully updated, comprehensive, and consistent art program. Helps readers grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. Includes summary boxes that assist with rapid review and mastery of key material. Student ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references and animations, designed to produce a more rounded learning experience. Features updates from cover to cover, including tumor immunity (tumor antigens, cancer immunotherapy), immune checkpoints, cytosolic sensors for DNA, non-canonical inflammasomes, prionization as a signaling mechanism, monogenic defects in immunity, and more.

  • 315.00 lei

    Mount Sinai Expert Guides: Allergy and Clinical Immunology will provide trainees in allergy and immunology with an extremely clinical and accessible handbook covering the major disorders and symptoms, their diagnosis and clinical management. Perfect as a point-of-care resource on the hospital wards and also as a refresher for board exam preparation, the focus throughout is on providing rapid reference, essential information on each disorder to allow for quick, easy browsing and assimilation of the must-know information. All chapters follow a consistent template including the following features: · An opening bottom-line/key points section · Classification, pathogenesis and prevention of disorder · Evidence-based diagnosis, including relevant algorithms, laboratory and imaging tests, and potential pitfalls when diagnosing a patient · Disease management including commonly used medications with dosages, management algorithms and how to prevent complications · How to manage special populations, ie, in pregnancy, children and the elderly · The very latest evidence-based results, major society guidelines and key external sources to consult In addition, the book comes with a companion website housing extra features such as case studies with related questions for self-assessment, key patient advice and ICD codes. Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be. If you're specialising in allergy and immunology and require concise, practical and clinical guidance from one of the world's leading institutions in this field, then this is the perfect book for you.

  • 320.00 lei

    Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. In print and online with additional resources, this reference is the up-to-date and readable textbook you need to master the complex subject of immunology.

    New to this edition
    • Stay abreast of the latest advances in immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more.

    • Visualize immunologic processes more effectively through a completely revised art program with redrawn figures, a brighter color palette, and more 3-dimensional art.


    • Find information more quickly and easily through a reorganized chapter structure and a more logical flow of material.

  • 37500lei 340.00 lei

    With all the complex issues of acceptance or rejection of a transplanted organ, immunology is a key subject for all transplantation clinicians. During recent years, there has been an explosion of research and knowledge in this area. Produced in association with the American Society of Transplantation, and written by experts within the field, Transplant Immunology provides a comprehensive overview of the topic in relation to clinical transplantation. Starting with the basic functionality of the immune system, it then moves on to cover the very latest developments in immunosuppressive drugs and protocols, as well as a look at all emerging technologies in the field.

  • 70600lei 365.00 lei

    Allergy is developing into one of the most prevalent diseases affecting individuals in the very early days of life. While the cause of this epidemic is still unclear, it appears that the westernized life style is playing an important role, which includes nutrition, possibly air pollution as well as hygienic conditions. While epidemiologic studies were able to narrow down these factors, basic research discovered novel mechanisms that control the organism´s tolerance against allergens. Particularly interesting is the role of microorganisms that colonize or infect a host and thereby cause damage and immunological activation followed by sensitization or exacerbation of already existing sensitizations. However at the same time microbial activation of the immune system can help to generate a protective immunity that prevents allergen sensitization. The current book is collecting these evidences and connects epidemiologic and clinical mechanistic knowledge. Only the synthesis of this knowledge will help to find solutions to the ongoing allergy epidemic in terms of public health activities, prevention and therapy.

  • 45200lei 407.00 lei

    This highly practical, easy-to-read, fully updated and expanded resource offers a wide range of targeted guidelines and insights in allergy medicine. Written by a leading allergy clinician -- along with a renowned group of nationally recognized expert contributors in allergy and immunology, pulmonary, and infectious diseases -- this title is a proven resource for front-line general practitioners, especially primary care physicians. The most clinically relevant information is provided on the pathophysiology, diagnosis, treatment, and prevention of all major allergic disorders. Each chapter has a section on “Evidence-Based Medicine” that introduces one to two recent research publications on the subject, and several chapters have been written by new authors. Covering the entire scope of adult and pediatric allergy and asthma and organized by specific organ which guides the reader to diagnostic and therapeutic solutions quickly and easily, the book offers a wealth of outstanding illustrations, key concepts, management protocols, and updated references. An invaluable contribution to the field, Allergy and Asthma: Practical Diagnosis and Management, 2nd Edition will be of immense value not only to primary care physicians, but also to fellows in training, residents, nurses, nurse practitioners, and medical and allied health students.

  • 47500lei 425.00 lei

    Description: The third edition of Pediatric Allergy continues this title's steadfast tradition of providing comprehensive, authoritative guidance on the day-to-day diagnosis and management of pediatric allergic and immunologic diseases. You'll have the most up-to-date research at hand thanks to an easily accessible full-color format that highlights a host of new chapters, extensive updates, and clinically focused coverage. Whether you're a student, resident, pediatrician or allergist, you'll appreciate this user-friendly and versatile source for providing optimal care!
    • Includes diagnostic tests available for asthma, upper respiratory allergy, and more.
    • Equips you with an understanding of the immune mechanisms underlying allergic diseases.
    • Features coverage of drug allergies and cross-reactivity.
    • Highlights clinical pearls discussing the best approaches to the care and treatment of pediatric patients.
    • Appendices listing common food allergies and autoantibodies in autoimmune diseases make for quick reference to essential material.
    New To This Edition:
    • Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.
    • Revised asthma section examines current asthma guidelines; school-centered asthma programs; exercise-induced asthma; and new directions in asthma therapy.
    • Includes the most current knowledge relating to emerging asthma within young children, medication adherence, and the impact of infection on the natural history of asthma.
    • New information on gene therapy, stem-cell therapy, and a host of new immunodeficiency diseases helps you obtain the best results from the therapeutics for pediatric allergic and immunologic diseases.
    • Features brand-new chapters on immunopathology; diagnostics and management; potential immunotherapeutic strategies for treating food allergies; current status of immunotherapy for food allergy; and biologic therapies.
    • Focused coverage of today's hot topics in pediatric allergy includes the use of targeted biologics to treat specific activation pathways leading to severe allergic diseases; defects of innate immunity; rheumatic diseases of childhood; and inflammatory disorders.
    • Discusses new studies examining potential etiologies for the increase in food allergy and examines potential immunotherapeutic strategies for treating food allergies.
    • New evidence-based principles of medical care help you make the best use of available medications for your patients.

  • 47000lei 425.00 lei

    The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs. The tolerance mechanisms include both tissue repair and immune regulatory effects. These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis. In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation.

  • 430.00 lei

    For decades, health care practitioners have relied on Middleton's Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton's Allergy Essentials, by Drs. Robyn E. O'Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that's both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management.

  • 52800lei 475.00 lei

    This volume opens by providing a comprehensive overview of the use and regulation of metals in our society, metal properties, and available testing methodologies. Common and uncommon metal allergens and sources of exposure are then reviewed in depth, detailing allergic responses and paying special consideration to select patient populations. In the general population, the prevalence of metal allergy is high. Environmental sources of metal exposure include jewelry, clothing, electronic devices, coins, leather, diet, and occupational exposure. Metal allergy may result in allergic contact dermatitis and systemic contact dermatitis, as well as several less common manifestations. Further, metal allergy has been associated with device failure and/or dermatitis following implantation of medical devices and dental implants. As metals are ubiquitous, this book will be indispensable for a wide range of clinicians and investigators. This handy reference will meet the needs of all health professionals and investigators who are interested in metal allergy and its diagnosis and management.

  • 52800lei 475.00 lei

    The book introduces the bioinformatics resources and tools available for the study of allergenicity. Allergy symptoms affect more than 25% of the population in industrialized countries. At the same time, biotechnology is a rapidly developing field, which often involves the introduction of potentially allergenic novel proteins into drugs or foods. It is essential to avoid transferring a gene that encodes a major allergenic protein (from any source) into a drug/food crop that did not previously contain that protein. Accurately distinguishing candidate genes from allergens before transferring them into a drug or food would aid preventive efforts to curb the rising incidence of allergies. Several public databases have been created in response to increasing allergen data. The resources provided by these databases have paved the way for the creation of specialized bioinformatics tools that allow allergenicity to be predicted. The book is a useful resource for biologists and biomedical informatics scientists, as well as clinicians. Dr. Ailin Tao is the chief of Guangdong Province Key Laboratory of Allergy & Clinical Immunology, Principal Investigator of the State Key Laboratory of Respiratory Disease, the Second Affiliated Hospital of Guangzhou Medical University; Dr. Prof. Eyal Raz is a Professor of Medicine at University of California, San Diego, La Jolla, California, USA.

  • 53300lei 480.00 lei

    Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world. As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention. Summarizes the current knowledge of the epidemiological, genetic, and cellular basis of allergic diseases Ideal reference for the study of allergies in young children, atopic dermatitis, allergic rhinitis, childhood asthma, and food allergies Provides landmark findings in the field of immunology and allergy development Fulfills the need for a book that focuses on primary and secondary allergy prevention, especially during the first years of life Unites key, global experts in the field who summarize their collective, and current, knowledge, along with novel ideas for potential options of prevention

  • 57200lei 515.00 lei

     When a biological drug patent expires, alternative biosimilar products are developed. The development of biosimilar products is complicated and involves numerous considerations and steps. The assessment of biosimilarity and interchangeability is also complicated and difficult.Biosimilar Drug Product Development presents current issues for the development of biosimilars and gives detailed reviews of its various stages and contributing factors as well as relevant regulatory pathways and pre- and post-approval issues.

  • 520.00 lei

    Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world. As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention. * Summarizes the current knowledge of the epidemiological, genetic, and cellular basis of allergic diseases* Ideal reference for the study of allergies in young children, atopic dermatitis, allergic rhinitis, childhood asthma, and food allergies* Provides landmark findings in the field of immunology and allergy development* Fulfills the need for a book that focuses on primary and secondary allergy prevention, especially during the first years of life* Unites key, global experts in the field who summarize their collective, and current, knowledge, along with novel ideas for potential options of prevention

  • 57700lei 520.00 lei

    Providing a unique A-Z guide to antibodies for immunohistology, this is an indispensable source for pathologists to ensure the correct application of immunohistochemistry in daily practice. Each entry includes commercial sources, clones, descriptions of stained proteins/epitopes, the full staining spectrum of normal and tumor tissues, staining pattern and cellular localization, the range of conditions of immunoreactivity, and pitfalls of the antibody's immunoprofile, giving pathologists a truly thorough quick-reference guide to sources, preparation and applications of specific antibodies. Appendices provide useful quick-reference tables of antibody panels for differential diagnoses, as well as summaries of diagnostic applications. Expanded from previous editions with over forty new entries, this handbook for diagnostic, therapeutic, prognostic and research applications of antibodies is an essential desktop book for practicing pathologists as well as researchers, residents and trainees.
      • The third edition of the Manual of Diagnostic Antibodies for Immunohistology, fully updated with over forty new entries, outlining the specificities of monoclonal and antisera antibodies and their key uses
      • Highlights caveats and how to avoid the most common problems in practical application of immunohistochemistry
      • Each entry follows a standard structure for quick and easy access and retrieval of information

  • 58700lei 530.00 lei

    To celebrate the 40th anniversary of the discovery of Natural Killer (NK) cells, this volume focuses on the recent advances in our understanding of NK cell development and differentiation and their acquisition of functional properties, as well as the latest models for NK-cell analysis in mice and applications in clinical medicine. NK cells have travelled a circuitous path from their initial description as ‘spontaneous killers’ (for some simply an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of action in immune defense and an important mediator of immune reactivity in health and disease. Together, these reviews provide a timely and concise picture of the evolution of NK cells as essential agents in immunity and as potent weapons against disease. This book offers an appealing and insightful resource for scientists and clinicians.

  • 64600lei 580.00 lei

    This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.

  • 70600lei 635.00 lei

    This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.

  • 73300lei 660.00 lei

    This book explores the recent advances and integrations in molecular technology in food research platforms, which have revolutionized the way we discover and trace potential allergens in our food and drugs and how we utilize that for diagnosis and management. These different technologies for global allergenomic profiling in different kinds of food are discussed, including mass spectrometry, chromatography, and nuclear magnetic resonance. The book also addresses multiomics research with bioinformatics strategies in food allergy in terms of allergen characterization and quantitation, and covers applications in food allergy research from discovery to routine analysis.

  • 820.00 lei

    The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world.

          The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

    Table of contents (10 chapters)


    ·         Introduction on Primary Immunodeficiency Diseases

    Rezaei, Nima (et al.)

    Pages 1-81

    ·         Combined T- and B-Cell Immunodeficiencies

    Deist, Françoise (et al.)

    Pages 83-182

    ·         Predominantly Antibody Deficiencies

    Aghamohammadi, Asghar (et al.)

    Pages 183-244

    ·         Phagocytes Defects

    Wintergerst, Uwe (et al.)

    Pages 245-294

    ·         Genetic Disorders of Immune Regulation

    Speckmann, Carsten (et al.)

    Pages 295-338

    ·         Defects in Intrinsic and Innate Immunity: Receptors and Signaling Components

    Parvaneh, Nima (et al.)

    Pages 339-392

    ·         Autoinflammatory Disorders

    Berg, Stefan (et al.)

    Pages 393-435

    ·         Complement Deficiencies

    Mahmoudi, Maryam (et al.)

    Pages 437-460

    ·         Other Well-Defined Immunodeficiencies

    Gennery, Andrew R. (et al.)

    Pages 461-517

    ·         Syndromic Immunodeficiencies

    Ming, Jeffrey E. (et al.)

    Pages 519-551

  • 1,08000lei 900.00 lei

    The Atlas of Sexually Transmitted Diseases and Differential Diagnosis is a complete course through the most important sexual diseases. Counting with about 1000 figures, this atlas focuses on the peculiar characteristics of each of these diseases and in the relevant aspects for a proper differential diagnosis. It is authored by MDs with a deep knowledge in the field, providing a very comprehensive casuistry. Throughout the book the reader will have access to hundreds of pictures discussing about the most important sexually transmitted diseases. Each chapter will approach a different disease, providing a broad sort of images, since a microscopic perspective until the most classical genital lesions and characteristics, considering also systemic manifestations. Every figure is presented with a descriptive and instructive legend, providing the reader with all possible related information. Additionally, every chapter begins with an explanatory and introductory text disclosing about key aspects of the disease, such as etiopathogenesis; clinical manifestation; clinical, laboratorial and differential diagnosis; treatment and prevention.

  • Laboratory Models for Foodborne Infections
    La comanda in aprox. 4 saptamani
    1,06300lei 955.00 lei

     Resulting from ingestion of inappropriately prepared or stored foods containing pathogenic viruses, bacteria, fungi and parasites, foodborne infections have become a significant source of human morbidity and mortality worldwide in recent decades. This may be largely attributable to the remarkable popularity of convenient, ready-to-eat food products, the dramatic expansion of international food trades, and the continuing growth of immuno-suppressed population groups. Although anti-microbial treatments have played a crucial part in the control of foodborne infections in the past, the emergence and spread of anti-microbial resistance render the existing treatments ineffective. Additionally, our limited understanding of the molecular mechanisms of foodborne infections has thwarted our efforts in the development of efficacious vaccines for foodborne pathogens. 

    Given the obvious benefits of laboratory models in foodborne disease research, a great number of experiments have been conducted toward the elucidation of host-pathogen interactions in and pathogenic mechanisms of foodborne infections. Forming part of the Food Microbiology series, Laboratory Models for Foodborne Infections presents a state-of-the-art review of laboratory models that have proven valuable in deciphering the life cycle, epidemiology, immunobiology, and other key aspects of foodborne pathogens. 

    Written by scientists with respective expertise in foodborne pathogen research, each chapter includes a contemporary summary of a particular foodborne viral, bacterial, fungal, or parasitic infection in relation to its life cycle, epidemiology, clinical features, pathogenesis, host-pathogen interactions, and other related aspects. Besides providing a trustworthy source of information for undergraduates and postgraduates in food microbiology, Laboratory Models for Foodborne Infections offers an invaluable guide for scientists and food microbiologists with interest in exploiting laboratory models for detailed study of foodborne infections.

  • 1,23400lei 1110.00 lei

    Mucosal Immunology, now in its fourth edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. Most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes, making this subject an area of singular importance in the field of immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective, and excellent organization. It covers immune system topics, such as inductive and effector tissues and cells, and development and physiology of the mucosal barrier; diseases in the digestive system, respiratory tract, and genitourinary tract; and immunodeficiency. The most comprehensive text on mucosal immunology from internationally recognized experts in the field Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases Contains nine new chapters and an expanded appendix