pe pagina
  • 70.00 lei

    This book is intended to be concise yet highly informative and user friendly. It provides quick information of drug doses, adverse effects, contraindications of use and special precautions which has to be undertaken during therapy. The contents will be especially helpful not only for the students, but also for the busy practitioners. The clinical pearls and the comparative study of drugs discussed at the end of the chapters are for instant overview. This book precisely covers almost all important chapters of Pharmacology and would provide important at hand information for postgraduate aspirants too for their entrance examinations.

  • 115.00 lei



    Lippincott’s Photo Atlas of Medication Administration uses the nursing process format to provide step-by-step nursing skills with rationales. In addition to comprehensive photographs to illustrate steps, the Photo Atlas also contains documentation guidelines and samples, and Unexpected Situations, which explain how to respond to unanticipated outcomes. Topics include preparing medications as well as administering medications by various routes.


    Table of Contents:


    Skill 1 Administering Oral Medications

    Skill 2 Administering Medications via a Gastric Tube

    Skill 3 Removing Medication From an Ampule

    Skill 4 Removing Medication From a Vial

    Skill 5 Mixing Medications From Two Vials in One Syringe

    Skill 6 Administering an Intradermal Injection

    Skill 7 Administering a Subcutaneous Injection

    Skill 8 Administering an Intramuscular Injection

    Skill 9 Administering a Continuous Subcutaneous Infusion: Applying an Insulin Pump

    Skill 10 Administering Medications by Intravenous Bolus or Push Through an Intravenous Infusion

    Skill 11 Administering a Piggyback Intermittent Intravenous Infusion of Medication

    Skill 12 Administering an Intermittent Intravenous Infusion of Medication via a Mini-Infusion Pump

    Skill 13 Administering Medications by Intravenous Bolus or Push Through a Medication or Drug-Infusion Lock

    Skill 14 Administering Medication via a Metered-Dose Inhaler (MDI)

    Skill 15 Administering Medication via a Dry Powder Inhaler

    Skill 16 Administering Medication via a Small-Volume Nebulizer

    Skill 17 Administering Eye Drops

    Skill 18 Administering Ear Drops

    Skill 19 Administering a Nasal Spray 111


  • 125.00 lei

    A full-color manual derived from Goodman & Gilman's The Pharmacological Basis of Therapeutics. Goodman & Gilman's The Manual of Pharmacology and Therapeutics offers concise, authoritative coverage of class-specific and disease-specific drugs, organized primarily by organ/system. Derived from Goodman & Gilman's Pharmacological Basis of Therapeutics, Twelfth Edition and further updated, this streamlined text focuses on the principles of medical pharmacology and drug therapy and delivers coverage of all major drug classes. More than a pocket drug guide, this powerful resource covers: General Principles; Neuropharmacology; Modulation of Cardiovascular, Pulmonary, and Renal Function; Inflammation, Immunomodulation, and Hematopoiesis; Hormones and Hormone Antagonists; Drugs Affecting Gastrointestinal Function; Chemotherapy of Microbial Diseases; Chemotherapy of Neoplastic Diseases; and Special Systems Pharmacology, including Environmental Toxicology. The text explains the physiology and pathophysiology of major organ systems and pathogens with respect to pharmacotherapy and the mechanisms of drug action. With a new full color design and numerous tables, charts, and illustrations that highlight, explain, and summarize important information, Goodman & Gilman's Manual of Pharmacology and Therapeutics is essential wherever knowledge of drug actions and interactions is required

  • 18800lei 160.00 lei



    Covering the essential basic science and principles of pharmacology using concise text and diagrams, Dale’s Pharmacology Condensed, 3rd Edition, presents the key facts and concepts that are key to understanding how drugs work and their underlying pathophysiological processes. Each chapter provides an organized, consistent approach to efficient learning and retention of complex information. This concise text is an ideal companion volume to Rang and Dale’s Pharmacology, as well as a stand-alone condensed textbook or review book for exams.

    Table Of Contents:

    Section 1: Pharmacology and Drug Use

    1 Preface

    2 Pharmacology, Drug Names, and Classification


    Section 2: Fundamentals of Pharmacology

    3 General Principles of Drug Action

    4 Molecular Aspects of Drug Action

    5 Pharmacokinetic and Other Factors Influencing Drug Action

    6 Pharmacodynamics and the Measurement of Drug Action

    Section 3: Drug Development

    7 Drug Discovery and the Development of Small Molecules

    8 Drug Discovery and the Development of Biologicals

    9 Drug Safety, Toxicology, and Pharmacovigilance

    10 Regulation of Drug Use

    Section 4: Drug Actions on Body Systems

    11 Outline of Transmission and Drug Action in the Nervous System

    12 Drugs and Neurological Disorders

    13 Drugs and Pain

    14 Drugs and the Cardiovascular System

    15 Drugs and Blood: Haematopoiesis and Haemostasis

    16 Drugs and the Inflammatory and Immune Response

    17 Drugs and the Endocrine and Metabolic Systems

    18 Drugs and the Renal System

    19 Drugs and the Pulmonary System

    20 Drugs and the Musculoskeletal System

    21 Drugs and the Gastrointestinal System

    22 Drugs and the Kidney and Genitourinary System

    23 Drugs and the Skin

    24 Drugs and the Eye

    25 Drugs and the Ear

    26 Drugs Used in Anaesthesia

    27 Drug Use in Disorders of Nutrition

    28 Drug Use in Dentistry

    Section 5: Drugs to Treat Infectious Diseases and Neoplasms

    29 Antiviral Drugs

    30 Antibacterial Drugs

    31 Antifungal Drugs

    32 Drugs and Parasites: Anti-protozoal and Antihelminthic Drugs

    33 Drugs and Cancer

    Section 6: Drugs in the Community

    34 Prescribing and Personalising Drug Treatments

    35 Venoms, Toxins, Poisons, and Herbs

    36 Drug Dependence and Drug Abuse



  • 17700lei 170.00 lei



    Organized in conjunction with Rang and Dale’s Pharmacology 9th editionRang & Dale's Pharmacology Flashcards helps you review what you learn in class and reinforce essential information. One side of each flashcard features a diagram of the pathophysiological processes including the drug class at the top of the card. The back of the card details essential information for that drug class including actions, mechanism of action, pharmacokinetic aspects, adverse effects, the names of related drugs and important aspects of clinical use.

    Completely updated with the latest knowledge in pharmacology and clinical use.

    New chapter on drugs used for eye and skin conditions, new coverage of clinical use of biopharmaceuticals in a wide range of conditions, and a concise explanation of the rapidly growing impact of pharmacogenetics.

    Clinical correlations help you apply information to real-life situations.

    Compact and efficient size make it easy to carry selected cards with you and study on the go.

    A perfect study aid and complement to Rang & Dale’s Pharmacology, 9th Edition–—ideal for exam preparation.


    Table of Contents:


    Section I Cholinergic pharmacology

    1.01 Muscarinics – Eye

    1.02 Antimuscarinics – Eye

    1.03 Antimuscarinics – Gastrointestinal

    1.04 Antimuscarinics – Bladder

    1.05 Neuromuscular Blocker

    1.06 Neuromuscular Blocker

    1.07 Peripheral Anticholinesterases

    1.08 Nicotinic Partial Agonists

    Section II Noradrenergic pharmacology

    2.01 β2-Receptor Agonist

    2.02 β1-Receptor Antagonist

    2.03 α- and β-Receptor Agonists

    2.04 α1-Receptor Antagonist

    2.05 β1-Receptor Agonist

    2.06 α1-Receptor Agonist

    2.07 Drugs That Release Noradrenaline

    2.08 Selective β3-Adrenoceptor Agonist

    2.09 α2-Agonist Prodrug

    2.10 DOPA Decarboxylase Inhibitor

    Section III Inflammation and anti-inflammatory drugs

    3.01 NSAIDs

    3.02 NSAIDs

    3.03 NSAIDs

    3.04 COX-2 Inhibitors

    3.05 DMARDs

    3.06 DMARDs

    3.07 DMARDs

    3.08 Uricosuric Agents

    3.09 Antigout: Colchicine


    Section IV Drugs affecting the immune response

    4.01 Calcineurin Inhibitors

    4.02 Antiproliferative Immunosuppressant

    4.03 Antiproliferative Immunosuppressant

    4.04 Antiproliferative Antibiotic

    4.05 Glucocorticoids

    4.06 TNF Inhibitors

    4.07 Antibodies Against CD20

    4.08 Monoclonal Antibodies (non-CD20)

    4.09 Interleukin Inhibitors

    4.10 JAK

    4.11 Non-Sedating Antihistamines

    4.12 Sedating Antihistamine

    4.13 Drugs Affecting the Immune Response

    Section V Antidysrhythmic drugs

    5.01 Class Ia Antidysrhythmic

    5.02 Class Ic Antidysrhythmic

    5.03 Class II Antidysrhythmic

    5.04 Class III Antidysrhythmic

    5.05 Class IV Antidysrhythmic

    5.06 Adenosine Receptor Agonists

    5.07 Cardiac Glycoside

    Section IV The vascular system

    6.01 ACE Inhibitors

    6.02 Angiotensin Antagonists

    6.03 Calcium Channel Blockers

    6.04 Potassium Channel Activator

    6.05 Hydralazine

    6.06 Endothelin Antagonist

    Section VII The heart

    7.01 Nitrates

    7.02 Ivabradine

    7.03 Ranolazine

    Section VIII Drugs for eye and skin conditions

    8.01 Glaucoma Eyedrops


    8.02 VEGF Inhibitors


    8.03 Retinoids

    8.04 Treatment of Psoriasis


    8.05 Skin Parasites


    Section IX Atherosclerosis and lipoprotein metabolism

    9.01 HMG-CoA Reductase Inhibitors

    9.02 Fibrates

    9.03 PCSK9 Inhibitors

    9.04 Cholesterol-Absorption Inhibitors

    9.05 Cholesterol-Absorption Inhibitors

    Section X Haemostasis and thrombosis

    10.01 Irreversible COX-1 Inhibitor

    10.02 Adenosine (P2Y12) Antagonists

    10.03 GPIIb/IIIa Receptor Antagonists

    10.04 Other Antiplatelets Drugs

    10.05 Plasminogen Activators

    10.06 Plasminogen Inhibitor

    10.07 Anticoagulants

    10.08 Anticoagulants

    10.09 Anticoagulants

    10.10 Direct Oral Anticoagulants

    Section XI Haemopoietic system and treatment of anaemia

    11.01 Haematinic Agents

    11.02 Haematinic Agents

    11.03 Haematinic Agents

    11.04 Haemopoietic Growth Factors

    11.05 Haemopoietic Growth Factors

    Section XII Respiratory system

    12.01 β2-Receptor Agonists

    12.02 Xanthines

    12.03 Leukotriene Antagonists

    12.04 Inhaled Muscarinic Antagonists

    12.05 Inhaled Glucocorticoids

    12.06 Inhibitor of Mast Cells

    12.07 Inhibition of Interleukin-5

    12.08 Anti-Fibrotic Agents


    Section XIII Kidney

    13.01 Loop Diuretics

    13.02 Thiazide Diuretics

    13.03 Potassium-Sparing Diuretics

    13.04 Osmotic Diuretic

    Section XIV Gastrointestinal tract drugs

    14.01 H2 Antagonist

    14.02 Proton Pump Inhibitors

    14.03 Mucosal Protectants

    14.04 Antacids

    14.05 Prostaglandin E Agonist

    14.06 5-HT3 Antagonists – Antiemetics

    14.07 Other Antiemetics

    14.08 Osmotic Laxatives

    14.09 Bulk Laxatives

    14.10 Stimulant Laxatives

    14.11 Faecal Softeners

    14.12 Other Drugs for Constipation

    14.13 Antidiarrhoeal Agent

    14.14 Other Drugs That Reduce GI Motility

    Section XV The control of blood glucose and drug treatment of diabetes mellitus

    15.01 Insulin

    15.02 Sulfonylureas

    15.03 Biguanides

    15.04 Meglitinides

    15.05 Glucagon-Like Peptide-1 Agonists

    15.06 Dipeptidyl Peptidase Inhibitors

    15.07 SGLT-2 Inhibitors

    15.08 α-Glucosidase Inhibitors

    15.09 Glucagon

    Section XVI The pituitary and the adrenal cortex

    16.01 Hypothalamic Hormones

    16.02 Hypothalamic Hormones

    16.03 Anterior Pituitary Hormones

    16.04 Posterior Pituitary Hormones

    16.05 Mineralocorticoid

    Section XVII The thyroid

    17.01 Thyroid Hormone Suppression

    17.02 Thyroid Hormone Replacement

    Section XVIII Bone metabolism

    18.01 Antiresorptive Drugs

    18.02 Antiresorptive Drugs

    18.03 Antiresorptive Drugs

    18.04 Antiresorptive Drugs

    18.05 Anabolic Agents

    18.06 Vitamin D Preparations

    Section XIX Reproductive system

    19.01 Oestrogens and Anti-Oestrogens

    19.02 Progestogens and Anti-Progestogens

    19.03 Combined Oral Contraceptive Pill

    19.04 Gonadotrophins

    19.05 Uterine Stimulants

    19.06 Uterine Stimulants

    19.07 Uterine Stimulants

    19.08 Oxytocin Antagonist

    19.09 Male Sex Hormone

    19.10 Anti-Androgens

    19.11 Phosphodiesterase Type V Inhibitors

    Section XX Neurodegenerative disorders

    20.01 Drugs Used in Parkinson's Disease

    20.02 Drugs Used in Parkinson's Disease

    20.03 Drugs Used in Parkinson's Disease

    20.04 Drugs Used in Parkinson's Disease

    20.05 Drugs Used in Parkinson's Disease

    20.06 Drugs Used in Parkinson's Disease

    20.07 Drugs Used in Alzheimer's Disease

    20.08 Drugs Used in Alzheimer's Disease

    20.09 Drugs Used in Multiple Sclerosis


    Section XXI General anaesthetics

    21.01 Inhalational Agents

    21.02 Inhalational Agents

    21.03 Intravenous Anaesthesia

    Section XXII Anxiolytics and hypnotic drugs

    22.01 Benzodiazepines

    22.02 Z-drugs

    22.03 Partial Serotonin Agonist

    22.04 Other Insomnia Drugs


    Section XXIII Antipsychotic drugs

    23.01 First-Generation Antipsychotics

    23.02 First-Generation Antipsychotics

    23.03 First-Generation Antipsychotics

    23.04 Second-Generation Antipsychotics

    23.05 Second-Generation Antipsychotics

    23.06 Second-Generation Antipsychotics

    23.07 Second-Generation Antipsychotics

    23.08 Second-Generation Antipsychotics

    Section XXIV Antidepressant drugs

    24.01 Tricyclics

    24.02 SSRIs

    24.03 SNRIs

    24.04 Noradrenaline Reuptake Inhibitor

    24.05 Monoamine Oxidase Inhibitors

    24.06 α-Adrenoceptor & 5-HT Receptor Antagonist

    24.07 Dopamine Reuptake Inhibitor

    24.08 Drugs for Bipolar Disorder

    24.09 Drugs for Bipolar Disorder


    Section XXV Antiepileptic drugs

    25.01 Sodium Channel Inhibitors

    25.02 T-Type Calcium Channel Blockers

    25.03 Broad-Spectrum Antiepileptic

    25.04 Benzodiazepines

    25.05 Barbiturates

    25.06 Broad-Spectrum Antiepileptic

    25.07 Broad-Spectrum Antiepileptic

    25.08 AMPA Receptor Blockers

    25.09 Broad-Spectrum Antiepileptic

    25.10 Other Anticonvulsants

    Section XXVI Analgesic drugs

    26.01 Opioid Drugs

    26.02 Opioid Drugs

    26.03 Opioid Drugs

    26.04 Opioid Drugs

    26.05 Drugs Used for Neuropathic Pain

    26.06 Drugs Used for Neuropathic Pain

    26.07 Drugs Used for Neuropathic Pain

    26.08 Other Analgesic Drugs


    Section XXVII Psychoactive drugs

    27.01 Psychomotor Stimulants

    27.02 Psychomotor Stimulants

    27.03 Psychomotor Stimulants

    27.04 CNS Depressants

    27.05 Other Psychoactive Drugs


    27.06 Major Psychedelic Drugs

    Section XXVIII Local anaesthetics

    28.01 Rapid-Onset LAs

    28.02 Slow- and Medium-Onset LAs

    28.03 Topical LA

    Section XXIX Antibacterial drugs

    29.01 Beta-Lactam Antibiotics

    29.02 Beta-Lactam Antibiotics

    29.03 Beta-Lactam Antibiotics

    29.04 Blockers of Peptidoglycan Synthesis

    29.05 Bacterial Protein Synthesis Blockers

    29.06 Bacterial Protein Synthesis Blockers

    29.07 Bacterial Protein Synthesis Blockers

    29.08 Bacterial Protein Synthesis Blockers

    29.09 Bacterial Protein Synthesis Blockers

    29.10 Antibiotics Affecting Topoisomerase

    29.11 Blockers of Folate Synthesis/Action

    29.12 Other Antibacterial Drugs


    29.13 Antimycobacterials for Tuberculosis


    29.14 Antimycobacterials for Leprosy


    Section XXX Antiviral drugs

    30.01 Reverse Transcriptase Inhibitors

    30.02 Reverse Transcriptase Inhibitors

    30.03 Protease Inhibitors

    30.04 DNA Polymerase Inhibitors

    30.05 Neuraminidase Inhibitors

    30.06 Biopharmaceutical Antivirals


    30.07 Drugs Used in HIV


    30.08 Drugs Used in Hepatitis


    Section XXXI Antiprotozoal drugs

    31.01 Blood Schizonticides – Malaria

    31.02 Tissue Schizonticide – Malaria

    31.03 Folate Inhibitors – Malaria

    31.04 Artemisinin Derivatives – Malaria

    31.05 Treatment of Amoebiasis

    31.06 Other Antiprotozoal Drugs

    Section XXXII Antifungal drugs

    32.01 Antifungal Antibiotics

    32.02 Synthetic Antifungal Drugs – Azoles

    32.03 Other Antifungal Drugs

    Section XXXIII Mebendazole

    33.01 Anthelminthic Drugs

    33.02 Anthelminthic Drugs

    33.03 Anthelminthic Drugs

    33.04 Anthelminthic Drugs

    33.05 Anthelminthic Drugs

    33.06 Anthelminthic Drugs

    33.07 Anthelminthic Drugs

    Section XXXIV Anticancer drugs

    34.01 Alkylating Agents and Similar Drugs

    34.02 Antimetabolites

    34.03 Cytotoxic Antibiotics

    34.04 Plant Derivatives

    34.05 Hormones

    34.06 Protein Kinase Inhibitors

    34.07 Monoclonal Antibodies

    34.08 Anticancer Drugs

    Section XXXV General principles

    35.01 Agonists and Antagonists

    35.02 Affinity

    35.03 Efficacy

    35.04 Competitive Antagonism

    Section XXXVI Genetic variation and personalized medicine

    36.01 Drug Efficacy

    36.02 Drug Safety

    36.03 Pharmacokinetics

    Section XXXVII Absorption and distribution of drugs

    37.01 Lipid Solubility and Ionization

    37.02 Routes of Drug Administration

    37.03 Bioavailability

    37.04 Measurement of Bioavailability

    37.05 Non-Target Binding of Drugs

    37.06 Volume of Distribution, Vd

    Section XXXVIII Drug metabolism and excretion

    38.01 Phase I and Phase II Metabolism

    38.02 Cytochrome P450 System

    38.03 P450 Induction and Inhibition

    38.04 Renal Excretion of Drugs

    38.05 Other Routes of Excretion

    Section XXXIX Pharmacokinetics

    39.01 First-Order Elimination

    39.02 Zero-Order Elimination

    39.03 Plasma Half-Life

    39.04 Clearance

    Drug Index


  • Pass the Preregistration Pharmacy Exam
    La comanda in aproximativ 4 saptamani
    170.00 lei

    Se tipareste doar la comanda !


    A revision book to help pharmacist students prepare for the pre-registration exam of the Royal Pharmaceutical Society of Great Britain (RPSGB) and other similar exams. It consists of over 400 multiple choice questions (MCQs), with explanatory answers, as well as an introductory chapter on exam preparation and four useful appendixes of abbreviations and symbols used in pharmacy. All the MCQs are written in the same style as the RPSGB pre-registration exam. The topics covered are core aspects of any pharmacy curriculum, making the book suitable for pharmacy students preparing for undergraduate exam and similar pre-registration exams in all parts of the world.


    • Over 400 multiple-choice questions cover all the topics in the pre-registration exam of the RPSGB.
    • All questions are written in the style of the RPSGB exam.
    • Four types of multiple-choice questions are given, covering all three parts of the pre-registration RPSGB — all in the same style as the exam.
    • Questions are grouped according to core pharmacy topics.
    • Explanations are thorough and helpful.
    • Four appendices provide helpful summaries of abbreviations and symbols used in pharmacy.

    Table Of Contents:

    1. Introduction to the Pre-registration exam
    2. Clinical pharmacy and therapeutics - closed and open book questions
    3. Pharmacy practice - closed and open book questions
    4. Pharmacy law and ethics - closed and open book questions
    5. Responding to symptoms - closed and open book questions
    6. Calculations - closed and open book questions
    7. Answers
    8. Appendices:
    I. Abbreviations of health and pharmacy organisations and technical terms
    II. Symbols used in pharmacy
    III. Latin terms and abbreviations
    IV. Abbreviations used in medical notes



  • Pharmacology Flash Cards
    La comanda in aproximativ 4 saptamani
    21500lei 190.00 lei


    Completely revised to correlate to Brenner and Stevens’ Pharmacology, 5th Edition, these beautifully illustrated flash cards cover the essential pharmacology concepts you need to know for course exams and the USMLE Step 1. Perfect for individual or group study, they’re ideal for quickly mastering must-know information in this challenging field.


    • Full-color cards cover hundreds of the most commonly used drugs, including name and pronunciation, drug class, mechanism of action (MOA), clinical use, special considerations, adverse effects, interactions, and similar drugs (generic and trade names).
    • Provides "need to know" information on every card and points you directly to where more detailed information can be found in the Brenner and Stevens’ textbook.
    • Content can be easily customized with your own notes or highlighting.
    • Student Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references to produce a more rounded learning experience.

    New To This Edition:

    NEW! 30 additional cards and comparison charts available on Student Consult™.

    Table Of Contents:

    Pharmacology Flash Cards
    Fourth Edition

    Section I: Autonomic, Autacoid, and Neuromuscular Drugs
    Section II: Cardiovascular Drugs
    Section III: Lipid, Coagulation, and Hematopoiesis Drugs
    Section IV: Central Nervous System Depressant Drugs
    Section V: Psychotherapeutic Drugs
    Section VI: Analgesic and Antimigraine Drugs
    Section VII: Neurodegenerative Disease Drugs and Antidotes
    Section VIII: Anesthetic Drugs
    Section IX: Gastrointestinal Drugs
    Section X: Respiratory Drugs and Antihistamines
    Section XI: Musculoskeletal Drugs
    Section XII: Endocrine Drugs
    Section XIII: Antibacterial Drugs
    Section XIV: Antifungal, Antiviral, and Antiparasitic Drugs
    Section XV: Antineoplastic And Immunosuppressant Drugs



  • 21500lei 190.00 lei

    Complementing the guidelines in the British National Formulary, the third edition of the Oxford Handbook of Clinical Pharmacy remains the indispensable guide to clinical pharmacy, providing all the information needed for practising and student pharmacists. It presents handy practical guidance in a quick-reference, bullet-point format to give the reader the knowledge and confidence needed to provide a clinical pharmacy service.

    Including key information on controlled drugs, adverse drug reactions, interactions, communication skills, and confidentiality, this extensively revised addition to the bestselling Oxford Handbook series is the fundamental pharmacy reference tool. It features chapters on adherence, anaphylaxis, clinical trials, herbal medicines, palliative care, patient management, pharmaceutical calculations, research, policy, and therapy related issues.

    Thoroughly revised and updated, the Oxford Handbook of Clinical Pharmacy includes brand new topics, including content on health coaching, residency and on-call, HIV and TB and mental health.

  • 23000lei 190.00 lei

    The 26th edition provides practical, evidence-based recommendations from the experts in antimicrobial therapy for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices. Drug descriptions cover pediatric-appropriate antimicrobial agents available today and include complete information about dosing regimens. New in the 26th edition: First pediatric approval of beta-lactam/beta-lactamase inhibitor for CRE (carbapenem-resistant enteric bacilli), ceftazidime-avibactam Replacement antibiotics for cefotaxime (lack of availability in the US), including ceftriaxone and cefepime (for neonates) Situations in which ceftaroline is preferred over vancomycin by the Editors for MRSA infections Updates on management of influenza, including baloxavir (now approved for children >12 years) New approaches to treatment of mucomycosis New recommendations for malaria More than 150 new references!

  • 24700lei 200.00 lei



    Every three years, The Harriet Lane Handbook is carefully updated by residents, edited by chief residents, and reviewed by expert faculty at The Johns Hopkins Hospital. Easy to use, concise, and complete, this essential manual keeps you current with new guidelines, practice parameters, pharmacology, and more. The 22nd Edition of this portable reference continues to be the #1 source of pediatric point-of-care clinical information for pediatric residents, students, nurses, and all healthcare professionals who treat young patients.


    Table of Contents:





    Part I. Pediatric Acute Care


    Chapter 1. Emergency and Critical Care Management

    I. Approach to the Unresponsive Child

    II. Management of Shock3,5,7,11

    III. Management of Common Emergencies

    IV. Critical Care Reference Data

    Chapter 2. Traumatic Injuries

    I. Components of the Trauma Assessment

    II. Head and Neck Trauma

    III. Concussion

    IV. Thoracic and Abdominal Trauma Evaluation18

    V. Orthopedic/Long Bone Trauma

    VI. Dental Trauma

    VII. Ophthalmologic Trauma26

    VIII. Animal Bites

    IX. Burns

    X. Nonaccidental Trauma

    XI. Resources

    Color Plates

    Chapter 3. Toxicology

    I. Initial Evaluation

    II. Toxidromes

    III. Ingestions and Antidotes

    IV. Acetaminophen Overdose7

    V. Lead Poisoning8

    VI. Web Resources

    Chapter 4. Procedures

    I. General Guidelines

    II. Ultrasound for Procedures

    III. Neurologic Procedures: Lumbar Puncture2,3

    IV. Otolaryngologic Procedures

    V. Cardiovascular Procedures

    VI. Pulmonary Procedures

    VII. Gastrointestinal Procedures

    VIII. Genitourinary Procedures

    IX. Musculoskeletal Procedures

    X. Skin/Dermatologic Procedures

    XI. Online Content

    Part II. Diagnostic and Therapeutic Information


    Chapter 5. Adolescent Medicine

    I. Adolescent Health Maintenance

    II. Sexual Health

    III. Transitioning Adolescents Into Adult Care51

    IV. Web Resources

    Chapter 6. Analgesia and Procedural Sedation

    I. Pain Assessment

    II. Analgesics1

    III. Patient-Controlled Analgesia (PCA)

    IV. Opioid Tapering

    V. Procedural Sedation1,9–12,19–21

    VI. Web Resources

    Chapter 7. Cardiology

    I. Physical Examination

    II. Electrocardiography

    III. Congenital Heart Disease

    IV. Acquired Heart Disease

    V. Imaging

    VI. Procedures

    VII. Common Cardiac Complaints

    VIII. Exercise Recommendations for Patients With Congenital Heart Disease

    IX. Lipid Monitoring Recommendations

    X. Cardiovascular Screening

    XI. Web Resources

    Chapter 8. Dermatology

    I. Evaluation and Clinical Descriptions of Skin Findings

    II. Vascular Anomalies1

    III. Infections

    IV. Hair Loss (Figs. 8.18–8.20, Color Plates)

    V. Acne Vulgaris

    VI. Common Neonatal Dermatologic Conditions (Fig. 8.21; Figs. 8.22–8.30, Color Plates)

    VII. Autoimmune and Allergic Dermatologic Conditions (Figs. 8.31–8.38, Color Plates)

    X. Online Content

    Color Plates

    Chapter 9. Development, Behavior, and Developmental Disability

    I. Developmental Definitions1,2

    II. Guidelines for Normal Development and Behavior

    III. Developmental Screening and Evaluation of Developmental Disorders

    IV. Specific Disorders of Development

    V. Longitudinal Care of Children With Developmental Disorders and Disabilities

    VI. Transitions From Pediatric to Adult Care for Youth With Developmental Disabilities

    VII. Web Resources

    Chapter 10. Endocrinology

    I. Diabetes

    II. Thyroid Gland14-16

    III. Parathyroid Gland and Vitamin D22-24

    IV. Adrenal Gland25-29

    V. Disorders of So dium and Water Regulation35

    VI. Growth35-37

    VII. Sexual Development39-45

    VIII. Neonatal Hypoglycemia Evaluation51,52

    IX. Additional Normal Values

    X. Web Resources

    Chapter 11. Fluids and Electrolytes

    I. Introduction

    II. Fluid Resuscitation

    III. Electrolyte Management

    IV. Algorithm for Evaluating Acid-Base Disturbances7,17,18

    Chapter 12. Gastroenterology

    I. Gastrointestinal Emergencies

    II. Conditions of the Gastrointestinal Tract

    III. Conditions of the Liver

    IV. Pancreatitis30-32

    V. Web Resources

    Chapter 13. Genetics: Metabolism and Dysmorphology

    I. Metabolism1-7

    II. Newborn Metabolic Screening7

    III. Dysmorphology7,11-14

    IV. Patterns of Dysmorphologic Conditions11,14

    V. Etiologies of Dysmorphic Features (Fig. 13.5)11,14,29

    VI. Consent and Disclosure of Genetic Testing

    VII. Web Resources


    VIII. Online Content

    Chapter 14. Hematology

    I. Anemia

    II. Neutropenia

    III. Thrombocytopenia and Impaired Platelet Function

    IV. Coagulation

    V. Blood Component Replacement

    VI. Additional Resources

    VII. Online Content

    Chapter 15. Immunology and Allergy

    I. Allergic Rhinitis1–6

    II. Food Allergy7–12

    III. Drug Allergy13,14

    IV. Evaluation of Suspected Immunodeficiency

    V. Immunoglobulin Therapy22–25

    VI. Immunologic Reference Values

    Chapter 16. Immunoprophylaxis

    I. Immunization Schedules

    II. Immunization Guidelines

    III. Postexposure Prophylaxis (Table 16.5)

    V. Counseling and Communication about Vaccines16-26

    VI. Web Resources27-33

    VII. Online Content

    Chapter 17. Microbiology and Infectious Disease

    I. Common Neonatal and Pediatric Infections: Guidelines for Diagnosis and Initial Management

    II. Microbiology

    III.Spectra of Activity for Commonly Used Antibiotics (Fig. 17.6)

    IV. Exposures to Blood Borne Pathogens and Prophylaxis

    Chapter 18. Neonatology

    I. Newborn resuscitation

    II. Routine Newborn Care of a Term Infant

    III. Newborn Assessment

    IV. Fluids, Electrolytes, and Nutrition

    V. Cyanosis in the Newborn

    VI. Respiratory Diseases

    VII. Apnea and Bradycardia

    VIII. Cardiac Diseases

    IX. Hematologic Diseases

    X. Gastrointestinal Diseases

    XI. Neurologic Diseases

    XII. Urologic Disorders

    XIII. Retinopathy of Prematurity34

    XIV. Commonly Used Medications in the Neonatal Intensive Care Unit

    XV. Web Resources

    XVI. Online Content

    Chapter 19. Nephrology

    I. Urinalysis1: Table 19.1

    II. Kidney Function Tests

    III. Chronic Hypertension5-7

    IV. Urinary Tract Infections8-13

    V. Proteinuria14–16

    VI. Hematuria18

    VII. Acute Kidney Injury19,20

    VIII. Chronic Kidney Disease23

    IX. Dialysis

    X. Tubular Disorders

    XI. Nephrolithiasis27-30

    XII. Web Resources

    Chapter 20. Neurology

    I. Neurologic Examination

    II. Headaches1–11

    III. Seizures12–25

    IV. Hydrocephalus26–28

    V. Ataxia29,30

    VI. Stroke31–33

    VII. Encephalopathy/Altered Mental Status34–37

    VIII. Neuromuscular Disorders38–45

    IX. Web Resources

    Chapter 21. Nutrition and Growth

    I. Assessment of Growth

    II. Management of Overweight and Obese Children

    III. Malnutrition in Infants and Children

    IV. Re-Feeding Syndrome

    V. Nutritional Needs of Healthy Children

    VI. Breastfeeding and the Use of Human Milk

    VII. Enteral Nutrition

    VIII. Parenteral Nutrition

    IX. Web Resources

    Chapter 22. Oncology

    I. Overview of Pediatric Malignancies1-4

    II.Pediatric Hematologic Malignancies1-2 (TABLE 22.1)

    V. Oncologic Emergencies2,9-16

    VI. Commonly Used Chemotherapeutic Drugs and Associated Acute Toxicities (TABLE 22.4)

    VIII. Antimicrobial Prophylaxis in Oncology Patients (TABLE 22.6)17-19

    IX. Hematopoietic Stem Cell Transplantation (HSCT)1,2,20

    X. Complications of hsct1,2,20-22

    XI. Cancer survivorship3,23-25

    XII. Web Resources

    XIII. Online content

    Chapter 23. Palliative Care

    I. Introduction to Hospice and Palliative Medicine

    II. Communication and Decision Making

    III. Care of the Dying Child

    IV. Web Resources

    Chapter 24. Psychiatry

    I. Overview

    II. Postpartum Depression

    III. Common Psychiatric Conditions in Children (2 To 12 Years)

    IV. Common Psychiatric Conditions in Adolescents

    V. Psychiatric Emergencies

    VI. Web Resources

    Chapter 25. Pulmonology and Sleep Medicine

    I. Evaluation of Pulmonary Gas Exchange

    II. Pulmonary Function Tests (PFT)

    III. Asthma12,18

    IV. Bronchiolitis19-23

    V. Bronchopulmonary Dysplasia (BPD)24-27

    VI. Cystic Fibrosis28-37

    VII. Obstructive Sleep Apnea Syndrome (OSAS)38-42

    VIII. Infant and Child Sleep43-46

    IX. Brief Resolved Unexplained Event (BRUE)47,48

    X. Web Resources


    XI. Online Content

    Chapter 26. Radiology

    I. General Pediatric Principles

    II. Choosing the Right Study

    III. Head

    IV. Neck and Airway

    V. Chest

    VI. Heart (see Chapter 7)

    VII. Abdomen

    VIII. Genitourinary Tract

    IX. Musculoskeletal

    X. Confirming Tube Placement and Line Insertion

    XII. Web Resources

    Chapter 27. Rheumatology

    I. Brief Overview of Clinical Characteristics of Rheumatologic Diseases

    II. Interpretation of Laboratory Studies Used in the Diagnosis and Monitoring of Rheumatologic Diseases

    III. Primary Care Management of Rheumatologic Diseases363839

    IV. Web Resources

    Part III. Reference


    Chapter 28. Blood Chemistry and Body Fluids

    I. Reference Values

    II. Evaluation of Body Fluids

    III. Conversion Formulas

    Chapter 29. Biostatistics and Evidence-Based Medicine

    I. Evidence-Based Medicine

    II. Biostatistics and Epidemiology

    III. Web Resources

    Part IV. Formulary


    Chapter 30. Drug Dosages

    I. Note to Reader

    III. Explanation of Breastfeeding Categories

    IV. Explanation of Pregnancy Categories

    V. Nomogram and Equation for Body Surface Area

    VI. Drug Index

    Chapter 31. Drugs in Renal Failure

    I. Dose Adjustment Methods

    II. Antimicrobials Requiring Adjustment in Renal Failure

    III. Nonantimicrobials Requiring Adjustment in Renal Failure




    Pediatric Cardiac Arrest



  • 210.00 lei


    Students’ favorite review resource for studying the essentials of medical pharmacology, Lippincott® Illustrated Reviews: Pharmacology , Seventh Edition, presents up-to-date drug information in an accessible format ideal for a fast, effective refresher.

    Part of the popular Lippincott® Illustrated Reviews series, this concise resource features clear, effective writing and hundreds of illustrations that break down complex information for rapid review. Sequential images present mechanisms of action and focus on showing rather than telling students how drugs work, and review questions with answers deliver powerful, practical exam preparation.

    Updated drug information reflects the most current, clinically relevant pharmacology material.

    Approachable outline format distills complex information for easier review.

    High-quality illustrations reinforce understanding in vibrant detail.

    Enhanced review questions with answers test students’ understanding and identify areas for further study.




  • 23600lei 215.00 lei

    The Fifth Edition of Luellmann's Color Atlas of Pharmacology has been extensively revised to include all recent advances and new drugs, and the illustrations have been optimized and updated. Each two-page spread presents concise text on the left complemented by detailed full-color illustrations on the right to help users quickly digest important facts and concepts.

    Color-coded sections provide readers with a helpful framework with which to approach the latest developments in pharmacology.

    • Part 1, General Pharmacology, explains basic aspects, such as drug absorption, distribution, and elimination, along with the molecular mechanisms of drug actions
    • Part 2, Systems Pharmacology, presents the different groups of drugs, emphasizing their functional and therapeutic aspects
    • Part 3, Therapy of Selected Diseases, provides all the relevant information regarding the pharmacological treatment of a large number of conditions

    Key features:

    • User-friendly format ideal for study and review, self-assessment, and quick reference
    • Completely revised and updated, with 174 color plates
    • New glossary of important and interesting pharmacological terms
    • Updated detailed drug indexes containing current information on drugs listed by both generic and brand names

    The Fifth Edition of Color Atlas of Pharmacology is an essential study guide and reference for every student, nurse, and practicing physician needing to keep up to date with recent advances in the field.

  • 240.00 lei



    Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals.
    The mathematics involved is notoriously difficult, but this much-praised and well established textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students.


    Worked calculation examples and self-assessment test questions aid continuous learning reinforcement throughout

    Frequent use of figures and diagrams clarify points made in the text

    Practical examples are used to show the application of techniques

    Key points boxes summarise the need to know information for each topic

    Focuses on the most relevant and frequently used techniques within the field

    Table Of Contents:

    Chapter 1 Control of the quality of analytical methods
    Chapter 2 Physical and chemical properties of drug molecules
    Chapter 3 Titrimetric and chemical analysis methods
    Chapter 4 Ultraviolet and visible spectroscopy
    Chapter 5 Infrared spectrophotometry
    Chapter 6 Atomic spectrophotometry
    Chapter 7 Molecular emission spectroscopy
    Chapter 8 Nuclear magnetic resonance spectroscopy
    Chapter 9 Mass spectrometry
    Chapter 10 Chromatographic theory
    Chapter 11 Gas chromatography
    Chapter 12 High-performance liquid chromatography
    Chapter 13 Thin-layer chromatography
    Chapter 14 High-performance capillary electrophoresis
    Chapter 15 Extraction methods in pharmaceutical analysis
    Chapter 16 Methods used in the quality control of biotechnologically produced drugs
    Chapter 17 Electrochemical biosensors



  • 26000lei 240.00 lei


    The most up-to-date, comprehensive, and authoritative pharmacology text in health medicine--enhanced by a new full-color illustrations

    Organized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, Fourteenth Edition covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors' many years' experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.

    To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations (many new to this edition), Basic & Clinical Pharmacologyfeatures numerous summary tables and diagrams that encapsulate important information.

    - Student-acclaimed summary tables conclude each chapter
    - Everything students need to know about the science of pharmacology and its application to clinical practice 
    - Strong emphasis on drug groups and prototypes 
    - NEW! 100 new drug tables
    - Includes 330 full-color illustrations, case studies, and chapter-ending summary tables 
    - Organized to reflect the syllabi of pharmacology courses 
    - Descriptions of important new drugs


    Table of Contents:


    Chapter 1: Introduction: The Nature of Drugs & Drug Development & Regulation

    Chapter 2: Drug Receptors & Pharmacodynamics

    Chapter 3: Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action

    Chapter 4: Drug Biotransformation

    Chapter 5: Pharmacogenomics


    Chapter 6: Introduction to Autonomic Pharmacology

    Chapter 7: Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs

    Chapter 8: Cholinoceptor-Blocking Drugs

    Chapter 9: Adrenoceptor Agonists & Sympathomimetic Drugs

    Chapter 10: Adrenoceptor Antagonist Drugs


    Chapter 11: Antihypertensive Agents

    Chapter 12: Vasodilators & the Treatment of Angina Pectoris

    Chapter 13: Drugs Used in Heart Failure

    Chapter 14: Agents Used in Cardiac Arrhythmias

    Chapter 15: Diuretic Agents


    Chapter 16: Histamine, Serotonin, & the Ergot Alkaloids

    Chapter 17: Vasoactive Peptides

    Chapter 18: The Eicosanoids: Prostaglandins, Thromboxanes,Leukotrienes, & Related Compounds

    Chapter 19: Nitric Oxide

    Chapter 20: Drugs Used in Asthma


    Chapter 21: Introduction to the Pharmacology of CNS Drugs

    Chapter 22: Sedative-Hypnotic Drugs

    Chapter 23: The Alcohols

    Chapter 24: Antiseizure Drugs

    Chapter 25: General Anesthetics

    Chapter 26: Local Anesthetics

    Chapter 27: Skeletal Muscle Relaxants

    Chapter 28: Pharmacologic Management of Parkinsonism &Other Movement Disorders

    Chapter 29: Antipsychotic Agents & Lithium

    Chapter 30: Antidepressant Agents

    Chapter 31: Opioid Agonists & Antagonists

    Chapter 32: Drugs of Abuse


    Chapter 33: Agents Used in Cytopenias; Hematopoietic Growth Factors

    Chapter 34: Drugs Used in Disorders of Coagulation

    Chapter 35: Agents Used in Dyslipidemia

    Chapter 36: Nonsteroidal Anti-Inflammatory Drugs,Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout


    Chapter 37: Hypothalamic & Pituitary Hormones

    Chapter 38: Thyroid & Antithyroid Drugs

    Chapter 39: Adrenocorticosteroids & Adrenocortical Antagonists

    Chapter 40: The Gonadal Hormones & Inhibitors

    Chapter 41: Pancreatic Hormones & Antidiabetic Drugs

    Chapter 42: Agents That Affect Bone Mineral Homeostasis


    Section VIII: Chemotherapeutic Drugs: Introduction

    Chapter 43: Beta-Lactam & Other Cell Wall- &Membrane-Active Antibiotics

    Chapter 44: Tetracyclines, Macrolides, Clindamycin,Chloramphenicol, Streptogramins, & Oxazolidinones

    Chapter 45: Aminoglycosides & Spectinomycin

    Chapter 46: Sulfonamides, Trimethoprim, & Quinolones

    Chapter 47: Antimycobacterial Drugs

    Chapter 48: Antifungal Agents

    Chapter 49: Antiviral Agents

    Chapter 50: Miscellaneous Antimicrobial Agents;Disinfectants, Antiseptics, & Sterilants

    Chapter 51: Clinical Use of Antimicrobial Agents

    Chapter 52: Antiprotozoal Drugs

    Chapter 53: Clinical Pharmacology of the Antihelminthic Drugs

    Chapter 54: Cancer Chemotherapy

    Chapter 55: Immunopharmacology


    Chapter 56: Introduction to Toxicology: Occupational &Environmental

    Chapter 57: Heavy Metal Intoxication & Chelators

    Chapter 58: Management of the Poisoned Patient


    Chapter 59: Special Aspects of Perinatal & Pediatric Pharmacology

    Chapter 60: Special Aspects of Geriatric Pharmacology

    Chapter 61: Dermatologic Pharmacology

    Chapter 62: Drugs Used in the Treatment of Gastrointestinal Diseases

    Chapter 63: Therapeutic & Toxic Potential of Over-the-Counter Agents

    Chapter 64: Dietary Supplements & Herbal Medications

    Chapter 65: Rational Prescribing & Prescription Writing

    Chapter 66: Important Drug Interactions & Their Mechanisms

    Appendix: Vaccines, Immune Globulins, & Other Complex Biologic Products


  • 29000lei 240.00 lei

    Catastrophes under anesthesia have focused attention on the interaction between drugs, including prescribed and non-prescribed medications, including interactions with vitamins, herbal preparations, traditional remedies, and food supplements. This book summarizes the adverse effects of a large range of drugs used in anesthesia.

  • 250.00 lei



    Instrument util pentru luarea deciziilor terapeutice adecvate

    Realizat intr-un format usor de utilizat, Manualul de Farmaco­terapie, Editia a zecea este un ghid util atat pentru profesionistii din farmacii, laboratoare, clinici, cat si pentru medicii, studentii si rezidentii din domeniu.

    Pentru ca farmacistul sa devina un furnizor de servicii de asistența de sanatate, este necesara dez­voltarea competențelor, in cadrul pregatirii postuniversitare, atat prin rezidentiat si prin programe de educatie continua, cat si prin studiu individual. Accesul la surse de informare obiective este esential pentru o educatie de calitate, iar Manualul de Farmacoterapie poate fi un real sprijin in procesul de formare continua.

    Ghidul ofera informatia esențiala pentru peste 140 de boli si afectiuni intalnite cel mai frecvent in practica clinica. Informatiile sunt prezentate sub forma de text, tabele, figuri sau algoritmi de tratament, totul pentru a facilita utilizarea si ințelegerea acestora.


    Fiecare capitol este organizat intr‑o maniera similara, consecventa:

                 • Definirea starii de boala

                 • Prezentarea concisa a elementelor de fiziopatologie relevante

                 • Tablou clinic

                 • Diagnostic

                 • Tratament

                 • Evaluarea rezultatelor terapiei


    Reactiile alergice si alte tulburari induse de medicamente, cum sunt cele hematologice, hepatice, pulmonare si renale sunt prezentate sub forma tabelara, in cinci anexe: Alergia la medicamente, Afectare hematologica indusă de medicamente, Afectare hepatica indusa de medicamente, Afectare pulmonara indusa de medicamente si Afectare renala indusa de medicamente. O alta anexa, de asemenea in format tabelar, include informatii privind managementul farmaco­terapiei la varstnici.


    Traducerea si ingrijirea materialului a fost realizata de o echipa de 70 de profesionisti din domeniul farmaceutic, care include cadre didactice ale facultatilor de farmacie din tara (UMF Cluj, UMF Iasi, UMF Bucuresti), far­macisti specialisti in specialitatea farmacie clinica, medici si farmacisti rezidenti.





    1. Guta si hiperuricemia

    2. Artroza

    3. Osteoporoza

    4. Artrita reumatoida



    5. Sindroamele coronariene acute

    6. Aritmiile

    7. Stopul cardiac

    8. Dislipidemiile

    9. Insuficiența cardiaca

    10. Hipertensiunea arteriala

    11. Boala cardiaca ischemica

    12. Socul

    13. Accidentul vascular cerebral

    14. Tromboembolismul venos



    15. Acneea vulgara

    16. Reactii dermatologice ale medicamentelor si afectiuni cutanate frecvente

    17. Psoriazisul



    18. Afectiunile glandei suprarenale

    19. Diabetul zaharat

    20. Afectiunile glandei tiroide



    21. Ciroza si hipertensiunea portală

    22. Constipatia

    23. Diareea

    24. Boala de reflux gastroesofagian

    25. Hepatitele virale

    26. Boala inflamatorie intestinala

    27. Greata si varsaturile

    28. Pancreatita

    29. Ulcerul gastroduodenal



    30. Contraceptia

    31. Terapia hormonala in menopauza, perimenopauza si postmenopauza

    32. Sarcina si alaptarea: consideratii terapeutice



    33. Anemiile

    34. Siclemia



    35. Alegerea regimului antimicrobian

    36. Infectiile sistemului nervos central

    37. Endocardita infectioasa

    38. Infecțtile fungice invazive

    39. Infectiile gastrointestinale

    40. Infectia cu virusul imunodeficientei umane

    41. Gripa

    42. Infectiile intraabdominale

    43. Infectiile tractului respirator inferior

    44. Infectiile tractului respirator superior

    45. Sepsisul si socul septic

    46. Bolile cu transmitere sexuala

    47. Infectiile cutanate si ale tesuturilor moi

    48. Profilaxia antibiotica in chirurgie

    49. Tuberculoza

    50. Infectiile tractului urinar

    51. Vaccinuri, toxoizi si alte imunobiologice



    52. Boala Alzheimer

    53. Epilepsia

    54. Cefaleea: migrena si cefaleea de tip tensional

    55. Managementul durerii

    56. Boala Parkinson

    57. Statusul epileptic



    58. Obezitatea

    59. Evaluare nutriționala si suport



    60. Cancerul mamar

    61. Cancerul colorectal

    62. Cancerul pulmonar

    63. Limfoamele

    64. Cancerul de prostata



    65. Glaucomul



    66. Tulburarea de anxietate generalizata, tulburarea de panica si tulburarea de stres posttraumatic

    67. Tulburarea bipolara

    68. Tulburarea depresiva majora

    69. Schizofrenia

    70. Tulburarile ciclului somn‑veghe

    71. Tulburarile cauzate de consumul de substante



    72. Dezechilibrele acido‑bazice

    73. Insuficienta renala acuta

    74. Boala renala cronica

    75. Homeostazia electrolitica



    76. Rinita alergica

    77. Astmul bronsic

    78. Bronhopneumopatia obstructiva cronica




    79. Hiperplazia benigna de prostata

    80. Disfunctia erectila

    81. Incontinenta urinara



    ANEXA 1. Alergia la medicamente

    ANEXA 2. Geriatrie

    ANEXA 3. Afectare hematologica indusa de medicamente

    ANEXA 4. Afectare hepatica indusa de medicamente

    ANEXA 5. Afectare pulmonara indusa de medicamente

    ANEXA 6. Afectare renala indusa de medicamente







    Coordonatorul editiei in limba romana

    Adina Popa

    Conferentiar dr., Disciplina de Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hatieganu”, Cluj‑Napoca


    Colectivul de verificare si validare

    Corina Bricis

    Sef de lucrari dr., Disciplina de Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hatieganu”, Cluj‑Napoca

    Diana Negru

    Farmacist dr., MUSO SRL Romania

    Cristina Pop

    Sef de lucrari dr., Disciplina de Farmacologie, Fiziologie si Fiziopatologie, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hatieganu”, Cluj‑Napoca

    Daniela Primejdie

    Sef de lucrari dr., Disciplina de Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hatieganu”, Cluj‑Napoca


    Colectivul de traducere

    Capitolul 1 Cosmina Vircan, Farmacist specialist farmacie clinica, Farmacia Veroli, Cluj‑Napoca

    Capitolul 2 Irina Cazacu, Asistent universitar dr., Disciplina de Farmacologie, Fiziologie si Fiziopatologie, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolul 3 Denisa Baica, Farmacist specialist farmacie clinica, Terapia SA, Cluj‑Napoca

    Capitolele 4 și 55 Veronica Bild, Profesor universitar dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Grigore T. Popa”, Iasi

    Capitolele 5 și 69 Imola Borcsa, Farmacist, Farmacia Ambrosia, Targu Secuiesc

    Capitolul 6 Oana Cristina Șeremet, Sef de lucrari dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Alexandra Mihaela Tanase, Asistent universitar, Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Capitolul 7 Cristina Elena Zbarcea, Conferentiar dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie, „Carol Davila”, Bucuresti

    Capitolul 8 Diana Negru, Farmacist dr., MUSO SRL, Romania

    Capitolele 9, 74 și 78 Alina Grecu, Farmacist specialist farmacie clinica, Farmacia Astra, Brasov

    Capitolul 10 Simona Negres, Profesor universitar dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Cornel Chirița, Profesor universitar dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Capitolul 11 Cristina Daniela Marineci, Asistent universitar, Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Capitolele 12 și 79 Oana Rad, Farmacist specialist farmacie clinica, Farmacia Veroli, Cluj‑Napoca

    Capitolul 13 Anca Zanfirescu, Sef de lucrari dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Capitolul 14 Bruno Velescu, Conferentiar universitar dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Emil Ștefanescu, Sef de lucrari dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Carol Davila”, Bucuresti

    Capitolele 15, 16 și 17 Mirela Moldovan, Conferentiar universitar, Disciplina de Dermatofarmacie si Cosmetologie, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolul 18 Adriana Vidican, Farmacist specialist farmacie clinica, Spitalul Clinic Municipal „Dr. G. Curteanu”, Oradea

    Capitolul 19 Anamaria Cristina, Asistent universitar, Disciplina de Farmacologie, Fiziologie si Fiziopatologie, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolul 20 Ana Varadi, Farmacist, Farmacia Yucca Bodesti, Neamt

    Capitolul 21 Andreea Pricopie, Farmacist specialist farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolele 22 și 26 Alexandra Cristina Epure, Farmacist specialist farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolele 23, 27 și Anexele 1, 5, 6 Ligia Hui, Farmacist specialist farmacie clinica, Spitalul Clinic Municipal Cluj‑Napoca

    Capitolul 24 Ingrid Telecan, Farmacist, ProductLife Group Romania

    Capitolul 25 și Anexa 3 Adina Torje, GP clinical pharmacist, Lea Vale Medical Group Luton, Marea Britanie

    Capitolele 28 și 38 Teodora Curean, Farmacist, ProductLife Group Romania

    Capitolul 29 Laura Todea, Farmacist specialist farmacie clinica, Pharmafarm Cluj

    Capitolele 30, 31 și 80 Cristina Pop, Sef de lucrari dr., Disciplina de Farmacologie, Fiziologie si Fiziopatologie, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hatieganu”, Cluj‑Napoca

    Capitolul 32 Corina Briciu, Sef de lucrari dr., Disciplina de Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolul 33 Adela Cozlac, Farmacist specialist farmacie clinica, Farmacia Ducfarm, Cluj‑Napoca

    Capitolele 34 și 50 Liana Moise, Farmacist, Richter Gedeon Romania

    Capitolul 35 și Anexa 2 Daniela Primejdie, Sef de lucrari dr., Disciplina de Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hatieganu”, Cluj‑Napoca

    Capitolele 36 și 47 Amalia Cosma, Farmacist specialist farmacie clinică, Clinical data coordinator Medpace, Leuven, Belgia

    Capitolul 37 Gabriel Marc, Asistent universitar, Disciplina de Chimie farmaceutica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolul 39 Laura Aldea-David, Farmacist specialist farmacie clinica, Sciformix a Covance Company, Romania

    Capitolele 40 și 49 Roxana Dobrota, Farmacist specialist farmacie clinica, Farmacia Elmafarm, Cluj‑Napoca

    Capitolul 41 Ioana Docea, Farmacist specialist farmacie clinica, Spitalul de Pneumoftiziologie, Aiud

    Capitolul 42 Andrada Mirișan, Farmacist specialist farmacie clinica, Spitalul Judeţean de Urgenţa „Dr. Constantin Opris”, Baia Mare

    Capitolul 43 Denisa Grozav, Farmacist specialist farmacie clinica, Farmacia Elmafarm, Cluj‑Napoca

    Capitolul 44 Monica Ciornei, Farmacist rezident farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolele 45 și 73 Iulia Anghel, Farmacist specialist farmacie clinica, Farmacia Elmafarm, Cluj‑Napoca

    Capitolul 46 Sándor Szabó, Farmacist specialist farmacie clinica, Training manager, Farmaciile Ropharma

    Capitolul 48 Iulia Popica, Farmacist specialist farmacie clinica, Farmacia Biofarm Șelimbar, Sibiu

    Capitolul 51 Codruta Heghes, Sef de lucrari dr., Disciplina de Analiza Medicamentului, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolele 52 și 56 Florentina Ban, Farmacist specialist farmacie clinica

    Capitolul 53 Mirela Voicu, Sef de lucrari dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Victor Babes”, Timisoara

    Cristiana Mabda, Asistent universitar, Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Victor Babes”, Timisoara

    Capitolul 54 și Anexa 4 Oana Bodea, Farmacist specialist farmacie clinica, ELC Group, Cluj‑Napoca

    Capitolul 57 Maria Suciu, Sef de lucrari dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Victor Babes”, Timişoara

    Valentina Buda, Asistent universitar, Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicină si Farmacie „Victor Babes”, Timişoara

    Capitolul 58 Eugenia Moldovan, Farmacist specialist farmacie clinica, Löwen Apotheke Esens, Germania

    Capitolul 59 Dalma Badar-Fülöp, Farmacist specialist farmacie clinica, Farmacia Ducfarm, Cluj‑Napoca

    Capitolul 60 Laura Budau, Farmacist, Centrul de Radioterapie Amethyst, Cluj‑Napoca

    Capitolul 61 Alexandra Zahan, Farmacist specialist farmacie clinica, Centrul Medical Cardiomed, Cluj‑Napoca

    Capitolul 62 Mariana Sipos, Farmacist specialist farmacie clinica, ProductLife Group România

    Capitolul 63 Andreea Vieru, Farmacist specialist farmacie clinica, Farmacia Napofarm, Cluj‑Napoca

    Capitolul 64 Sinziana Cetean, Asistent universitar dr., Disciplina de Chimie generala si anorganica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolul 65 Oana Ghinea, Farmacist specialist farmacie clinica, Farmacia Richter Gedeon, Campia Turzii

    Capitolele 66, 70 și 71 Maria Bonea, Asistent universitar, Disciplina de Psihiatrie si Psihiatrie pediatrica, Facultatea de Medicina, Universitatea de Medicina si Farmacie „Iuliu Hațieganu”, Cluj‑Napoca

    Capitolele 67 și 68 Ioana Nonn, Farmacist, Farmacia Victor Babes, Cluj‑Napoca

    Capitolul 72 Cristiana Arcălean, Farmacist specialist farmacie clinica, Spitalul Regina Maria, Cluj‑Napoca

    Capitolele 75 și 81 Aura Blendea, Farmacist specialist farmacie clinica, Spitalul Clinic Județean de Urgenta, Cluj‑Napoca

    Capitolul 76 Maria Brudiu, Farmacist specialist farmacie clinica, Spitalul Judetean de Urgența. Alba Iulia

    Capitolul 77 Carmen Cristescu, Profesor universitar dr., Disciplina de Farmacologie si Farmacie clinica, Facultatea de Farmacie, Universitatea de Medicina si Farmacie „Victor Babes”, Timisoara







  • 260.00 lei

     Pharmacotherapy Handbook, Tenth Edition delivers the essential  information students and practitioners need to quickly and confidently make drug therapy decisions for more than 140 of the diseases and disorders most commonly encountered in a clinical setting. Featuring a convenient alphabetized presentation, this handy guide utilizes text, tables, figures, and treatment algorithms to make important drug data readily accessible and easily understood.

    The consistent chapter organization consists of:

    • Disease state definition
    • Concise review of relevant pathophysiology
    • Clinical presentation
    • Diagnosis
    • Treatment
    • Evaluation of Therapeutic Outcomes

    Appendices include Allergic and Pseudoallergic Drug Reactions, Geriatrics, Drug-Induced Hematologic Disorders, Drug-Induced Liver Disease, Drug-Induced Pulmonary Disease, Drug-Induced Kidney Disease.

    You will find this to be the ideal carry-anywhere companion to Pharmacotherapy: A Pathophysiologic Approach, Tenth Edition by Joseph DiPiro

  • 26600lei 260.00 lei

    What do we do if different studies appear to give different answers? When applying research to questions for individual patients or for health policy, one of the challenges is interpreting such apparently conflicting research. A systematic review is a method to systematically identify relevant research, appraise its quality, and synthesize the results. The last two decades have seen increasing interest and developments in methods for doing high quality systematic reviews. Part I of this book provides a clear introduction to the concepts of reviewing, and lucidly describes the difficulties and traps to avoid. A unique feature of the book is its description, in Part II, of the different methods needed for different types of health care questions: frequency of disease, prognosis, diagnosis, risk, and management. As well as illustrative examples, there are exercises for each of the sections. This is essential reading for those interested in synthesizing health care research.

  • 30600lei 270.00 lei

     The Oxford Specialist Handbook of Urological Surgery returns fully updated for a second edition to guide the reader step-by-step through all types of urological operations. Including both background information on key urological problems and alternative surgical options, this Handbook is designed to guide the trainee through all aspects of urological surgery, from gaining clear and accurate consent to examining risks and complications of procedures.

    With each chapter written by subspecialty experts, this Handbook is packed with tips and tricks that offer practical and theatre-based advice gleaned over years of theatre experience to aid the reader. It also includes helpful pointers on aspects of surgery including patient positioning, indications and contraindications, types of incisions, and choice of ideal instrument, alongside aftercare and follow-up for the patient.

    Fully updated in accordance with new European guidelines and NICE clinical guidance, with extra topics on technological developments including robotic assisted surgery and a brand new chapter on female urology and incontinence, the Oxford Specialist Handbook of Urological Surgery is an essential resource for all urological trainees and junior doctors.

  • 30000lei 270.00 lei

    This spin-off from Stephen M. Stahl's new, completely revised, and fully updated sixth edition of the Prescriber's Guide covers the most important drugs in use today for treating depression. Now established as the indispensable formulary in psychopharmacology, easy to navigate and easy to use, the Prescriber's Guide combines evidence-based information with clinically informed guidance to support clinicians in making the most effective prescribing decisions for the good of their patients. Incorporating information on the newest indications, new formulations, new recommendations and new safety data, this edition continues to provide the essential practical support required by anyone prescribing in the field of mental health.

  • 31200lei 280.00 lei



    From reviews of the previous edition:

    ‘This new edition of Clinical Pharmacy and Therapeutics was really very helpful when I was doing an MSc course in Advancing Pharmacy Practice and it was really very helpful in all the clinical diseases I have to read for my PBL. I also used it as one of my most reliable reference books for the in-course simulation ward rounds and other clinical case studies. It is a great book to have as a practising clinical or hospital pharmacist or even community pharmacist. It will also be of great use to anyone doing a course in pharmacotherapy. This book will always be of use to you throughout your studentship or when practising after graduation. It is also more portable than most other pharmacotherapy textbooks with the same amount of information.’

    Now in its sixth edition, this best-selling, multi-disciplinary textbook continues to draw on the skills of pharmacists, clinicians and nurses to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of the pathophysiological processes, clinical pharmacy and the evidence base. Each chapter is co-written by a pharmacist and a clinician, and each chapter begins with key points and ends with cases to test understanding. The sixth edition is now on StudentConsult for the first time, giving online access to the full text.


    • Key points boxes at the beginning of each chapter
    • Case-study boxes throughout the chapters
    • Each chapter co-written by a pharmacist and a clinician
    • In-depth treatment of therapeutics to support pharmaceutical prescribing
    • Logical order and format: key points, epidemiology, aetiology, disease, clinical manifestations, investigations and treatment, drugs used in treatment.
    • Dosage reference sources given where appropriate, along with useful websites and further reading for each chapter.
    • Organised by body system

    New To This Edition:

    • New co-editor, Karen Hodson
    • Over 10 new authors
    • Now in 4-colour
    • On StudentConsult for the first time
    • New chapter on Dementia
    • Many new and revised illustrations
    • Chapters revised to include advances in therapeutics and changes to dose regimens and licensed indications
    • Updated case studies

    Table Of Contents:

    Section 1: General

    1. Clinical pharmacy process
    2. Prescribing
    3. Practical pharmacokinetics
    4. Drug interactions
    5. Adverse drug reactions
    6. Laboratory data
    7. Parenteral nutrition
    8. Pharmacoeconomics

    Section 2: Life stages

    1. Neonates
    2. Paediatrics
    3. Geriatrics

    Section 3: TherapeuticsGastrointestinal disorders

    1. Peptic ulcer disease
    2. Inflammatory bowel disease
    3. Constipation and diarrhoea
    4. Adverse effects of drugs on the liver
    5. Liver disease.
    6. Acute kidney injury
    7. Chronic kidney disease and end-stage renal disease
    8. Hypertension
    9. Coronary heart disease
    10. Chronic heart failure
    11. Arrhythmias
    12. Thrombosis
    13. Dyslipidaemia
    14. Asthma
    15. Chronic obstructive pulmonary disease
    16. Insomnia
    17. Anxiety disorders
    18. Affective disorders
    19. Schizophrenia
    20. Epilepsy
    21. Parkinson's disease
    22. Dementia
    23. Pain
    24. Nausea and vomiting
    25. Respiratory infections
    26. Urinary tract infections
    27. Gastrointestinal infections
    28. Infective meningitis
    29. Surgical site infection and antimicrobial prophylaxis
    30. Tuberculosis
    31. HIV infection.
    32. Fungal infections
    33. Thyroid and parathyroid disorders
    34. Diabetes mellitus
    35. Menstrual cycle disorders
    36. Menopause
    37. Drugs in pregnancy and lactation
    38. Prostate disease.
    39. Anaemia.
    40. Leukaemia
    41. Lymphomas
    42. Solid tumours.
    43. Rheumatoid arthritis and osteoarthritis
    44. Gout and hyperuricaemia
    45. Glaucoma
    46. Drug-induced skin disorders
    47. Eczema and psoriasis
    48. Wounds.

    Section 4: Appendices.



  • 32000lei 290.00 lei




    ‘The very last thing a drug regulator wishes to be able to say is, like Lord Byron (1788-1824), on the publication of his poem Childe Harold’s Pilgrimage, ‘I awoke one morning and found myself famous.’

    The twelfth edition of this long-established textbook of clinical pharmacology (first published in 1960) continues its fine tradition of balancing science and practice for improved evidence-based drug therapy and good prescribing in therapeutic settings increasingly complicated by intercurrent disease and polypharmacy.


    Coverage of all major therapeutic topics by body system.

    Introductory sections give brief chapter synopses.

    Case studies where relevant.

    Covers the needs of the developing world with a focus on practical prescribing and health technology assessment.

    Definition, tips, brief explanation boxes throughout.

    Interesting histories, etymologies and provenances of terms throughout.

    Entertaining footnotes throughout.

    New To This Edition:

    Fully updated throughout.

    New co-editor: Fraz Mir, Addenbrooke’s Hospital and Department of Medicine, University of Cambridge.

    Now with free e-book on StudentConsult.

    Table Of Contents:

    Section 1: General

    1 Clinical pharmacology

    2 Topics in drug therapy

    3 Discovery and development of drugs

    4 Evaluation of drugs in humans

    5 Health Technology Assessment

    6 Regulation of medicines

    7 Classification and naming of drugs

    Section 2: From Pharmacology to Toxicology

    8 General pharmacology

    9 Unwanted effects and adverse drug reactions

    10 Poisoning, overdose, antidotes

    11 Drug dependence

    Section 3: Infection and Inflammation

    12 Chemotherapy of infections

    13 Antibacterial drugs

    14 Chemotherapy of bacterial infections

    15 Viral, fungal, protozoal and helminthic infections

    16 Drugs for inflammation and joint disease

    17 Drugs and the skin

    Section 4: Nervous System

    18 Pain and analgesics

    19 Anaesthesia and neuromuscular block

    20 Psychotropic drugs

    21 Neurological disorders - epilepsy, Parkinson’s disease, and multiple sclerosis

    Section 5: Cardiorespiratory and Renal Systems

    22 Cholinergic and antimuscarinic (anticholinergic) mechanisms and drugs

    23 Adrenergic mechanisms and drugs

    24 Arterial hypertension, angina pectoris, myocardial infarction and heart failure

    25 Cardiac arrhythmia

    26 Hyperlipidaemias

    27 Kidney and genitourinary tract

    28 Respiratory system

    Section 6: Blood and Neoplastic Disease

    29 Drugs and haemostasis

    30 Cellular disorders and anaemias

    31 Neoplastic disease and immunosuppression

    Section 7: Gastrointestinal System

    32 Oesophagus, stomach and duodenum

    33 Intestines

    34 Liver, biliary tract, pancreas

    Section 8: Endocrine System, Metabolic Conditions

    35 Adrenal corticosteroids, antagonists, corticotropin

    36 Diabetes mellitus, insulin, oral antidiabetes agents, obesity

    37 Thyroid hormones, antithyroid drugs

    38 Hypothalamic, pituitary and sex hormones

    39 Vitamins, calcium, bone



  • 32000lei 300.00 lei



    World-renowned coverage of today’s pharmacology at your fingertips

    Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more.

    Includes access to unique features, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment.

    Features a color-coded layout for faster navigation and cross-referencing.

    Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout.


    Table of Contents:


    Rang and Dale's Pharmacology Ninth Edition Preface


    Section 1 General principles

    1 What is pharmacology?

    What Is a Drug?

    Origins and Antecedents

    Pharmacology in the 20Th and 21St Centuries

    References and Further Reading

    2 How drugs act


    Protein Targets for Drug Binding

    Desensitisation and Tolerance

    Quantitative Aspects of Drug–Receptor Interactions

    The Nature of Drug Effects

    References and Further Reading

    3 How drugs act

    Protein Targets for Drug Action

    Receptor Proteins

    Ion Channels as Drug Targets

    Control of Receptor Expression

    Receptors and Disease

    References and Further Reading

    4 How drugs act

    Regulation of Intracellular Calcium


    Muscle Contraction

    Release of Chemical Mediators

    Epithelial Ion Transport

    References and Further Reading

    5 How drugs act


    Protein and Oligonucleotide Biopharmaceuticals


    Gene Therapy

    Safety and Societal Issues

    Therapeutic Applications

    Concluding Remarks

    References and Further Reading

    6 Cell proliferation, apoptosis, repair and regeneration

    Cell Proliferation


    Apoptosis and Cell Removal

    Pathophysiological Implications

    Therapeutic Prospects

    References and Further Reading

    7 Cellular mechanisms


    The Innate Immune Response

    The Adaptive Immune Response

    Systemic Responses in Inflammation

    References and Further Reading

    8 Method and measurement in pharmacology


    Animal Models of Disease

    Pharmacological Studies in Humans

    Clinical Trials

    References and Further Reading

    9 Absorption and distribution of drugs


    Physical Processes Underlying Drug Disposition

    Drug Absorption and Routes of Administration

    Distribution of Drugs in the Body

    Special Drug Delivery Systems

    References and Further Reading

    10 Drug metabolism and elimination


    Drug and Metabolite Excretion

    References and Further Reading

    11 Pharmacokinetics

    Introduction: Definition and Uses of Pharmacokinetics

    Drug Elimination Expressed as Clearance

    Single-Compartment Model

    More Complicated Kinetic Models

    Population Pharmacokinetics

    Limitations of Pharmacokinetics

    References and Further Reading

    12 Individual variation, pharmacogenomics and personalised medicine


    Epidemiological Factors and Inter-Individual Variation of Drug Response

    Genetic Variation in Drug Responsiveness

    Therapeutic Drugs and Clinically Available Pharmacogenomic Tests


    References and Further Reading

    Section 2 Chemical mediators

    13 Chemical mediators and the autonomic nervous system

    Historical Aspects

    The Autonomic Nervous System

    Some General Principles of Chemical Transmission

    Basic Steps in Neurochemical Transmission: Sites of Drug Action

    References and Further Reading

    14 Cholinergic transmission

    Muscarinic and Nicotinic Actions of Acetylcholine

    Acetylcholine Receptors

    Nicotinic Receptors

    Physiology of Cholinergic Transmission

    Effects of Drugs on Cholinergic Transmission

    References and Further Reading

    15 Noradrenergic transmission


    Classification of Adrenoceptors

    Physiology of Noradrenergic Transmission

    Drugs Acting on Noradrenergic Transmission

    References and Further Reading

    16 5-Hydroxytryptamine and the pharmacology of migraine


    Migraine and Other Clinical Conditions in Which 5-HT Plays a Role

    References and Further Reading

    17 Purines


    Purinergic Receptors

    Adenosine as a Mediator

    ADP as a Mediator

    ATP as a Mediator

    Future Prospects

    References and Further Reading

    18 Local hormones 1


    What Is a ‘Mediator’?




    Other Important Fatty Acid Derivatives

    Platelet-Activating Factor

    Concluding Remarks

    References and Further Reading

    19 Local hormones 2


    General Principles of Protein and Peptide Pharmacology

    Biosynthesis and Regulation of Peptides




    Proteins and Peptides That Down-Regulate Inflammation

    Concluding Remarks

    References and Further Reading

    20 Cannabinoids

    Plant-Derived Cannabinoids and Their Pharmacological Effects

    Cannabinoid Receptors


    Synthetic Cannabinoids

    Clinical Applications

    References and Further Reading

    21 Nitric oxide and related mediators


    Biosynthesis of Nitric Oxide and Its Control

    Degradation and Carriage of Nitric Oxide

    Effects of Nitric Oxide

    Therapeutic Aspects

    Clinical Conditions in Which Nitric Oxide May Play A Part

    Related Mediators

    References and Further Reading

    Section 3 Drugs affecting major organ systems

    22 The heart


    Physiology of Cardiac Function

    Autonomic Control of the Heart

    Cardiac Natriuretic Peptides

    Ischaemic Heart Disease

    Drugs That Affect Cardiac Function

    References and Further Reading

    23 The vascular system


    Vascular Structure and Function

    Control of Vascular Smooth Muscle Tone

    Vasoactive Drugs

    Clinical Uses of Vasoactive Drugs

    References and Further Reading

    24 Atherosclerosis and lipoprotein metabolism



    Lipoprotein Transport

    Prevention of Atheromatous Disease

    Lipid-Lowering Drugs

    References and Further Reading

    25 Haemostasis and thrombosis


    Blood Coagulation

    Drugs That Act on the Coagulation Cascade

    Platelet Adhesion and Activation

    Fibrinolysis (Thrombolysis)

    References and Further Reading

    26 Haematopoietic system and treatment of anaemia


    The Haematopoietic System

    Types of Anaemia

    Haematinic Agents

    Haematopoietic Growth Factors

    Haemolytic Anaemia

    References and Further Reading

    27 Anti-inflammatory and immunosuppressant drugs


    Cyclo-Oxygenase Inhibitors

    Antirheumatoid Drugs

    Anticytokine Drugs and Other Biopharmaceuticals

    Drugs Used in Gout

    Antagonists of Histamine

    Possible Future Developments IN ANTIINFLAMMATORY THERAPY

    References and Further Reading

    28 Skin


    Structure of Skin

    Common Diseases of the Skin

    Drugs Acting on Skin

    Principal Drugs Used in Skin Disorders

    Agents Acting by Other Mechanisms

    Concluding Remarks

    References and Further Reading

    29 Respiratory system

    The Physiology of Respiration

    Pulmonary Disease and Its Treatment

    References and Further Reading

    30 The kidney and urinary system


    Outline of Renal Function

    The Structure and Function of the Nephron

    Drugs Acting on the Kidney

    Drugs That Alter the pH of the Urine

    Drugs That Alter the Excretion of Organic Molecules

    Drugs Used in Renal Failure

    Drugs Used in Urinary Tract Disorders

    References and Further Reading

    31 The gastrointestinal tract

    The Innervation and Hormones of the Gastrointestinal Tract

    Gastric Secretion


    The Motility of the GI Tract

    Drugs for Chronic Bowel Disease

    Drugs Affecting the Biliary System

    Future Directions

    References and Further Reading

    32 The control of blood glucose and drug treatment of diabetes mellitus


    Control of Blood Glucose

    Pancreatic Islet Hormones

    Diabetes Mellitus

    References and Further Reading

    33 Obesity


    Obesity as a Health Problem

    Homeostatic Mechanisms Controlling Energy Balance

    The Pathophysiology of Human Obesity

    Pharmacological Approaches to the Problem of Obesity

    New Approaches to Obesity Therapy

    References and Further Reading

    34 The pituitary and the adrenal cortex

    The Pituitary Gland

    The Adrenal Cortex

    New Directions in Glucocorticoid Therapy

    References and Further Reading

    35 The thyroid

    Synthesis, Storage and Secretion of Thyroid Hormones

    Regulation of Thyroid Function

    Actions of the Thyroid Hormones

    Transport and Metabolism of Thyroid Hormones

    Abnormalities of Thyroid Function

    Drugs Used in Diseases of the Thyroid

    References and Further Reading

    36 The reproductive system


    Endocrine Control of Reproduction

    Drugs Affecting Reproductive Function

    Drugs Used for Contraception

    The Uterus

    Erectile Dysfunction

    References and Further Reading

    37 Bone metabolism


    Bone Structure and Composition

    Bone Remodelling

    Disorders of Bone

    Drugs Used in Bone Disorders

    Potential New Therapies

    References and Further Reading

    Section 4 Nervous system

    38 Chemical transmission and drug action in the central nervous system


    Chemical Signalling in the Nervous System

    Targets for Drug Action

    Drug Action in the Central Nervous System

    The Classification of Psychotropic Drugs

    References and Further Reading

    39 Amino acid transmitters

    Excitatory Amino Acids


    γ-Aminobutyric Acid (GABA)


    Concluding Remarks

    References and further reading

    40 Other transmitters and modulators








    Other CNS Mediators

    A Final Message

    References and Further Reading

    41 Neurodegenerative diseases

    Protein Misfolding and Aggregation in Chronic Neurodegenerative Diseases

    Mechanisms of Neuronal Death

    Ischaemic Brain Damage

    Alzheimer's Disease

    Parkinson's Disease

    Huntington's Disease

    Amyotrophic Lateral Sclerosis

    Spinal Muscular Atrophy

    Multiple Sclerosis

    References and Further Reading

    42 General anaesthetic agents


    Mechanism of Action of Anaesthetic Drugs

    Intravenous Anaesthetic Agents

    Inhalation Anaesthetics

    Individual Inhalation Anaesthetics

    Balanced Anaesthesia

    References and Further Reading

    43 Analgesic drugs

    Neural Mechanisms of Pain

    Analgesic Drugs

    References and further reading

    44 Local anaesthetics and other drugs affecting sodium channels

    Local Anaesthetics

    Other Drugs That Affect Sodium Channels

    References and Further Reading

    45 Anxiolytic and hypnotic drugs

    The Nature of Anxiety and Its Treatment

    Measurement of Anxiolytic Activity

    Drugs Used to Treat Anxiety

    Delayed Anxiolytic Effect of SSRIs and Buspirone

    Drugs Used to Treat Insomnia (Hypnotic Drugs)

    References and Further Reading

    46 Antiepileptic drugs


    The Nature of Epilepsy

    Antiepileptic Drugs

    Muscle Spasm and Muscle Relaxants

    References and Further Reading

    47 Antipsychotic drugs


    The Nature of Schizophrenia

    Antipsychotic Drugs

    Future Developments

    References and Further Reading

    48 Antidepressant drugs

    The Nature of Depression

    Theories of Depression

    Antidepressant Drugs

    Clinical Effectiveness of Antidepressant Treatments

    Future Antidepressant Drugs

    Brain Stimulation Therapies

    Drug Treatment of Bipolar Disorder

    References and Further Reading

    49 Psychoactive drugs


    Psychomotor Stimulants

    Cognition-Enhancing Drugs

    Psychedelic Drugs

    Ketamine and Related Drugs


    Tolerance and Dependence

    Synthetic Cannabinoids

    References and Further Reading

    50 Drug abuse and dependence

    Drug Use and Abuse

    References and Further Reading

    Section 5 Drugs used for the treatment of infections and cancer

    51 Basic principles of antimicrobial chemotherapy


    The Molecular Basis of Chemotherapy

    Resistance to Antibacterial Drugs

    Current Status of Antibiotic Resistance in Bacteria

    References and Further Reading

    52 Antibacterial drugs


    Antibacterial Agents That Interfere With Folate Synthesis or Action

    β-Lactam Antibiotics and Other Agents That Interfere With Bacterial Wall or Membrane Synthesis

    Antimicrobial Agents Affecting Bacterial Protein Synthesis

    Antimicrobial Agents Affecting Topoisomerase

    Miscellaneous Antibacterial Agents

    Antimycobacterial Agents

    Possible New Antibacterial Drugs

    References and Further Reading

    53 Antiviral drugs

    Background Information About Viruses

    The Host–Virus Interaction

    HIV and AIDS

    Antiviral Drugs

    Combination Therapy for HIV

    Prospects for New Antiviral Drugs

    References and further reading

    54 Antifungal drugs

    Fungi and Fungal Infections

    Drugs Used to Treat Fungal Infections

    Future Developments

    References and Further Reading

    55 Antiprotozoal drugs


    Host–Parasite Interactions

    Malaria and Antimalarial Drugs

    Amoebiasis and Amoebicidal Drugs

    Trypanosomiasis and Trypanocidal Drugs

    Other Protozoal Infections and Drugs Used to Treat Them

    Future Developments

    References and Further Reading

    56 Antihelminthic drugs

    Helminth Infections

    Antihelminthic Drugs

    Resistance to Antihelminthic Drugs

    Vaccines and Other Novel Approaches

    References and Further Reading

    57 Anticancer drugs


    The Pathogenesis of Cancer

    General Principles of Cytotoxic Anticancer Drugs

    Anticancer Drugs

    Future Developments

    References and Further Reading

    Section 6 Special topics

    58 Harmful effects of drugs


    Classification of Adverse Drug Reactions

    Drug Toxicity

    Immunological Reactions to Drugs

    References and further reading

    59 Lifestyle and drugs in sport

    What Are Lifestyle Drugs?

    Classification of Lifestyle Drugs

    Drugs and Sex

    Drugs in Sport


    References and Further Reading

    60 Drug discovery and development

    The Stages of a Project


    Commercial Aspects

    Future Prospects

    A Final Word

    References and Further Reading



  • 34000lei 300.00 lei


    Designed to help you learn and retain key information in pharmacology, this foundational text takes you from course exams and the USMLE Step 1 right through to clinical practice. Brenner and Stevens’ Pharmacology, 5th Edition, focuses on the essential principles you need to know, in a concise yet comprehensive manner that’s easy to understand. Highly illustrated and formatted for quick reference, it’s your go-to text for the must-know aspects of pharmacology you’ll need for clinical problem solving and decision making.


    • Teaches the fundamental aspects of pharmacology using full-color illustrations, detailed explanations, and a consistent format to present classification of drugs for each system/disease.
    • Features useful tables, drug classifications boxes, case studies, and self-assessments in each chapter to help you review and prepare for course exams and Step 1.
    • Student Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and animations, designed to produce a more rounded learning experience. You’ll also find an additional glossary, chapter-by-chapter summaries and case studies, a full list of featured drugs, 150 USMLE-style questions, and more.

    New To This Edition:

    • Includes the latest pharmacologic mechanisms and applications with new and updated drug information throughout.

    Table Of Contents:

    Brenner and Stevens’ Pharmacology
    Fifth Edition

    Section I: Principles of Pharmacology
    Chapter 1 Introduction to Pharmacology
    Chapter 2 Pharmacokinetics
    Chapter 3 Pharmacodynamics
    Chapter 4 Drug Development and Safety
    Chapter 5 Toxicology and the Treatment of Poisoning

    Section II: Autonomic and Neuromuscular Pharmacology
    Chapter 6 Peripheral Neuropharmacology and Acetylcholine Agonists
    Chapter 7 Acetylcholine Receptor Antagonists
    Chapter 8 Sympathetic Neurotransmission and Adrenoceptor Agonists
    Chapter 9 Adrenoceptor Antagonists

    Section III: Cardiovascular, Renal, and Hematologic Pharmacology
    Chapter 10 Antihypertensive Drugs
    Chapter 11 Antianginal Drugs
    Chapter 12 Drugs for Heart Failure
    Chapter 13 Diuretics
    Chapter 14 Drugs for Cardiac Dysrhythmia
    Chapter 15 Drugs for Hyperlipidemia
    Chapter 16 Antithrombotic and Thrombolytic Drugs
    Chapter 17 Hematopoietic Drugs

    Section IV: Central Nervous System Pharmacology
    Chapter 18 Introduction to Central Nervous System Pharmacology
    Chapter 19 Sedative-Hypnotic and Anxiolytic Drugs
    Chapter 20 Antiepileptic Drugs
    Chapter 21 Local and General Anesthetics
    Chapter 22 Psychotherapeutic Drugs
    Chapter 23 Opioid Analgesics and Antagonists
    Chapter 24 Drugs for Neurodegenerative Diseases
    Chapter 25 Drugs of Abuse

    Section V: Pharmacology of Respiratory and Other Systems
    Chapter 26 Autacoid Drugs
    Chapter 27 Respiratory Pharmacology
    Chapter 28 Gastrointestinal Pharmacology
    Chapter 29 Drugs for Headache Disorders
    Chapter 30 Drugs for Pain, Inflammation, and Arthritic Disorders

    Section VI: Endocrine Pharmacology
    Chapter 31 Hypothalamic and Pituitary Drugs
    Chapter 32 Thyroid Drugs
    Chapter 33 Adrenal Steroids and Related Drugs
    Chapter 34 Drugs Affecting Fertility and Reproduction
    Chapter 35 Drugs for Diabetes
    Chapter 36 Drugs Affecting Calcium and Bone

    Section VII: Chemotherapy
    Chapter 37 Principles of Antimicrobial Chemotherapy
    Chapter 38 Inhibitors of Bacterial Cell Wall Synthesis
    Chapter 39 Inhibitors of Bacterial Protein Synthesis
    Chapter 40 Quinolones, Antifolate Drugs, and Other Antimicrobial Agents
    Chapter 41 Antimycobacterial Drugs
    Chapter 42 Antifungal Drugs
    Chapter 43 Antiviral Drugs
    Chapter 44 Antiparasitic Drugs
    Chapter 45 Antineoplastic and Immunomodulating Drugs

    Answers and Explanations to Review Questions



  • 310.00 lei



    Master key pharmacological concepts and practices with the most comprehensive, authoritative guide available Presented in full-color and packed with hundreds of illustrations, Basic and Clinical Pharmacology is the wide-ranging, engaging guide students have counted on for decades. Organized to reflect the course sequence in many pharmacology courses and in integrated curricula, the guide covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs Delivers the knowledge and insight needed to excel in every facet of pharmacology!. Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters New chapter on the increasingly relevant topic of cannabis pharmacology Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription Includes descriptions of important new drugs released through May 2019 New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters


    Table of Contents:


    Section I Basic Principles

    1. Introduction: The Nature of Drugs & Drug Development & Regulation

    2. Drug Receptors & Pharmacodynamics

    3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the time Course of Drug Action

    4. Drug Biotransformation

    5. Pharmacogenomics

    Section II Autonomic Drugs

    6. Introduction to Autonomic Pharmacology

    7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs

    8. Cholinoceptor-Blocking Drugs

    9. Adrenoceptor Agonists & Sympathomimetic Drugs

    10. Adrenoceptor Antagonist Drugs

    Section III Cardiovascular-Renal Drugs

    11. Antihypertensive Agents

    12. Vasodilators & the Treatment of Angina Pectoris

    13. Drugs Used in Heart Failure

    14. Agents Used in Cardiac Arrhythmias

    15. Diuretic Agents

    Section IV Drugs with Important Actions on Smooth Muscle

    16. Histamine, Serotonin, & the Ergot Alkaloids

    17. Vasoactive Peptides

    18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds

    19. Nitric Oxide

    20. Drugs Used in Asthma & Chronic Obstructive Pulmonary Disease

    Section V Drugs That Act in the Central Nervous System

    21. Introduction to the Pharmacology of CNS Drugs

    22. Sedative-Hypnotic Drugs

    23. The Alcohols

    24. Antiseizure Drugs

    25. General Anesthetics

    26. Local Anesthetics

    27. Skeletal Muscle Relaxants

    28. Pharmacologic Management of Parkinsonism & Other Movement Disorders

    29. Antipsychotic Agents & Lithium

    30. Antidepressant Agents

    31. Opioid Agonists & Antagonists

    32. Drugs of Abuse

    Section VI Drugs Used to Treat Diseases of the Blood, Inflammation, & Gout

    33. Agents Used in Cytopenias; Hematopoietic Growth Factors

    34. Drugs Used in Disorders of Coagulation

    35. Agents Used in Dyslipidemia

    36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout

    Section VII Endocrine Drugs

    37. Hypothalamic & Pituitary Hormones

    38. Thyroid & Antithyroid Drugs

    39. Adrenocorticosteroids & Adrenocortical Antagonists

    40. The Gonadal Hormones & Inhibitors

    41. Pancreatic Hormones & Glucose-Lowering Drugs

    42. Agents That Affect Bone Mineral Homeostasis

    Section VIII Chemotherapeutic Drugs

    43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics

    44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, Oxazolidinones, & Pleuromutilins

    45. Aminoglycosides & Spectinomycin

    46. Sulfonamides, Trimethoprim, & Quinolones

    47. Antimycobacterial Drugs

    48. Antifungal Agents

    49. Antiviral Agents

    50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants

    51. Clinical Use of Antimicrobial Agents

    52. Antiprotozoal Drugs

    53. Pharmacology of the Antihelminthic Drugs

    54. Cancer Chemotherapy

    55. Immunopharmacology

    Section IX Toxicology

    56. Introduction to Toxicology: Occupational & Environmental

    57. Heavy Metal Intoxication & Chelators

    58. Management of the Poisoned Patient

    Section X Special Topics

    59. Special Aspects of Perinatal & Pediatric Pharmacology

    60. Special Aspects of Geriatric Pharmacology

    61. Dermatologic Pharmacology

    62. Drugs Used in the Treatment of Gastrointestinal Diseases

    63. Cannabinoid Drugs

    64. Therapeutic & Toxic Potential of Over-the-Counter Agents

    65. Dietary Supplements & Herbal Medications

    66. Rational Prescribing & Prescription Writing

    67. Important Drug Interactions & Their Mechanisms

    Appendix: Vaccines, Immune Globulins, & Other Complex Biologic Products



  • 35700lei 320.00 lei



    Focusing on the essential aspects of pharmacology you need to know, Brody‘s Human Pharmacology, 6th Edition, keeps you fully up to date with all that’s new in the field. Streamlined content, a new organizational approach, enhanced online components, and thoroughly updated information ensure your grasp of key concepts and prepare you for exams. Nearly 500 full-color illustrations explain important processes, while color-coded boxes for major drugs, therapeutic overviews, clinical problems, and trade names reinforce your mastery of the information.

    Table Of Contents:

    Section 1 Mechanisms of Drug Action and Therapeutic Principles

    1. Introduction, Terminology

    2. Pharmacodynamics: Drug Targets (Receptors, Enzymes, DNA, etc)

    3. Pharmacokinetics

    4. Pharmacogenomics

    5. Drug Discovery, Development, and Regulation

    Section 2 Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses

    6. Introduction to the Peripheral Nervous Systems and Drugs for Peripheral Disorders

    Cholinergic Drugs

    7. Muscarinic Agonists and Their Clinical Uses

    8. Muscarinic Antagonists and Their Clinical Uses

    9. Nicotinic Agonists and Their Clinical Uses

    10. Nicotinic Antagonists and Neuromuscular Blocking Drugs

    Adrenergic Drugs

    11. Adrenergic Agonists and Their Clinical Uses

    12. Adrenergic Antagonists and Their Clinical Uses

    Section 3 Drug Treatment for Disorders Affecting the Central Nervous System

    13. Introduction to the CNS and Drugs Affecting the Brain

    Neurodegenerative Disorders

    14. Drug Therapy for Alzheimer's Disease and Other Cognitive Disorders/Dementias

    15. Pharmacotherapy of Basal Ganglia Disorders: Parkinson's Disease and Huntington's Disease

    16. Drug Therapy for Psychoses and Bipolar Disorder

    17. Drug Therapy for Depression and Anxiety

    18. Drug Therapy for the Management of Attention Deficit Hyperactivity Disorder

    19. Drug Therapy for Insomnia and the Hypersomnias

    20. Drug Therapy for Managing Obesity and Eating Disorders

    21. Treatment of Seizure Disorders

    22. Drug Therapy to Control Spasticity Disorders

    23. Ethanol, Other Alcohols, and Drugs for Alcohol Use Disorder

    24. Illicit Psychoactive Compounds and Substance Use Disorder

    Section 4 Drug Therapy for Pain Management

    25. Introduction

    26. General Anesthetics

    27. Local Anesthetics

    28. Opioid Analgesics

    29. Nonsteroidal Anti-inflammatory Agents and Acetaminophen

    30. Cannabinoids

    Section 5 Treatment of Inflammatory, Allergic and Immunologic Disorders

    31. Drug Therapy for Migraine Headache

    32. Drug Therapy for Gout and Hyperuricemia

    33. Drug Treatment for Allergic Reactions

    34. Immunosuppressants for Autoimmune Disorders and Organ Transplantation

    35. Drug Therapy for Rheumatoid Arthritis

    Section 6 Drug Treatment for Cardiovascular Diseases

    36. Introduction to The Cardiovascular System and the Regulation of Blood Pressure and Heart Rate

    37. Overview of Hypertension Management and Drugs that Decrease Sympathetic Tone

    38. Diuretics and Drugs that Affect Volume and Electrolyte Content

    39. Drugs Affecting the Renin-Angiotensin-Aldosterone System

    40. Calcium Channel Blockers

    41. Vasodilators

    42. Drug Therapy for Hyperlipidemias and Atherosclerotic Cardiovascular Disease

    43. Drug Therapy for Myocardial Ischemia and Angina Pectoris

    44. Treatment of Heart Failure: Cardiac Glycosides, Phosphodiesterase Inhibitors and Other Agents

    45. Antiarrhythmic Drugs

    46. Anticoagulant, Antiplatelet and Thrombolytic Agents

    47. Drug Therapy for Hemophilia and the Anemias

    Section 7 Treatment of Endocrine Disorders

    48. Introduction to Endocrine Pharmacology

    49. Treatment of Hypothalamic and Pituitary Disorders

    50. Treatment of Adrenalcorticosteroid Disorders

    51. Female Hormone Regulation

    52. Androgens, antiandrogens and their clinical uses

    53. Drug Therapy for the Management of Diabetes

    54. Drug Therapy for the Management of Thyroid Disorders

    55. Calcium Regulating Hormones and Agents Affecting Bone

    Section 8 Chemotherapy

    Infectious Diseases

    56. Principles of Antimicrobial Use

    57. Bacterial Cell Wall Synthesis Inhibitors

    58. Inhibitors of Protein Synthesis

    59. Drugs that Target DNA

    60. Antimycobacterial Drugs and the Treatment of Tuberculosis and Leprosy

    61. Drug Therapy for Resistant Organisms

    Parasitic Diseases

    62. Antifungal Agents

    63. Antimalarial and Other Antiprotozoal Agents

    64. Antihelmintics


    65. Drug Therapy for non-HIV Viral Infections

    66. Drugs for HIV and Related Opportunistic Infections


    67. Introduction and Therapeutic Principles

    68. Cytotoxic Agents

    69. Targeted Agents

    Section 9 Special Considerations

    70. Therapeutic Use of Hematopoietic Growth Factors, Vitamins and Minerals

    71. Gastrointestinal Disorders and Their Treatment

    72. Pharmacological Treatment of Asthma and COPD

    73. The Role of Neutraceuticals and Natural Products

    74. Essentials of Toxicology

    75. Therapeutic Considerations for Pregnant, Pediatric, Geriatric and Obese Individuals




  • 40000lei 330.00 lei


    The foremost text in this complex and fast-changing field, Medical Microbiology, 9th Edition, provides concise, up-to-date, and understandable explanations of key concepts in medical microbiology, immunology, and the microbes that cause human disease. Clear, engaging coverage of basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology help you master the essentials of microbiology―effectively preparing you for your coursework, exams, and beyond.

    Features significant new information on the human microbiome and its influence on the immune and other body systems, and new developments in microbial diagnosis, treatment, diseases, and pathogens.

    Updates every chapter with state-of-the-art information and current literature citations.

    Summarizes detailed information in tabular format rather than in lengthy text.

    Provides review questions at the end of each chapter that correlate basic science with clinical practice.

    Features clinical cases that illustrate the epidemiology, diagnosis, and treatment of infectious diseases.

    Introduces microbe chapters with summaries and trigger words for easy review.

    Highlights the text with clear, colorful figures, clinical photographs, and images that help you visualize the clinical presentation of infections.

    Offers additional study features online, including 200 self-assessment questions, microscopic images of the microbes, videos, and a new integrating chapter that provides hyperlinks between the microbes, the organ systems that they affect, and their diseases.


    Table of Contents:


    Section 1. Introduction

    1. Introduction to Medical Microbiology

    Historical Perspective






    Diagnostic Microbiology

    Microbiology and Immunology in the Clinic


    2. Human Microbiome in Health and Disease

    Human Microbiome Project

    Core Microbiome

    Evolution of the Microbiome and Normal Flora

    Role of the Microbiome in Disease

    Diagnostics and Therapeutics



    3. Sterilization, Disinfection, and Antisepsis




    Mechanisms of Action

    Section 2. General Principles of Laboratory Diagnosis

    4. Microscopy and In Vitro Culture


    In Vitro Culture

    5. Molecular Diagnosis

    Nonamplified Nucleic Acid Probes

    Nucleic Acid Analysis

    Protein Analysis

    6. Serologic Diagnosis


    Methods of Detection

    Immunoassays for Cell-Associated Antigen (Immunohistology)

    Immunoassays for Antibody and Soluble Antigen


    Section 3. Basic Concepts in the Immune Response

    7. Elements of Host Protective Responses

    Soluble Activators and Stimulators of Innate and Immune Functions

    Cells of the Immune Response

    8. Innate Host Responses

    Barriers to Infection

    Soluble Components of Innate Responses

    Cellular Components of Innate Responses

    Activation of Innate Cellular Responses

    Normal Flora–Associated Responses


    Bridge to Antigen-Specific Immune Responses

    9. Antigen-Specific Immune Responses

    Immunogens, Antigens, and Epitopes

    T Cells

    Cell-Surface Receptors of T Cells

    Development of T Cells

    Initiation of T-Cell Responses

    Activation of CD4 T Cells and Their Response to Antigen

    CD8 T Cells

    INNATE T Cells

    B Cells and Humoral Immunity

    B cells

    Immunoglobulin Types and Structures


    Antibody Response

    10. Immune Responses to Infectious Agents

    Antibacterial Responses

    Antiviral Responses

    Specific Immune Responses to Fungi

    Specific Immune Responses to Parasites

    Other Immune Responses


    Autoimmune Responses


    11. Antimicrobial Vaccines

    Types of Immunizations

    Immunization Programs

    Section 4. Bacteriology

    12. Bacterial Classification, Structure, and Replication

    Differences between Eukaryotes and Prokaryotes

    Bacterial Classification

    Bacterial Structure

    Structure and Biosynthesis of the Major Components of the Bacterial Cell Wall

    Cell Division


    13. Bacterial Metabolism and Genetics

    Bacterial Metabolism

    Human Bacterial Metabolism

    Bacterial Genes and Expression

    Bacterial Genetics

    14. Mechanisms of Bacterial Pathogenesis

    Entry into the Human Body

    Colonization, Adhesion, and Invasion

    Pathogenic Actions of Bacteria


    Mechanisms for Escaping Host Defenses


    15. Role of Bacteria in Disease

    16. Laboratory Diagnosis of Bacterial Diseases

    Specimen Collection, Transport, and Processing

    Bacterial Detection and Identification

    Antimicrobial Susceptibility Tests

    17. Antibacterial Agents

    Inhibition of Cell Wall Synthesis

    Inhibition of Protein Synthesis

    Inhibition of Nucleic Acid Synthesis

    Other Antibiotics

    18. Staphylococcus and Related Gram-Positive Cocci

    Physiology and Structure

    Pathogenesis and Immunity


    Clinical Diseases

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    19. Streptococcus and Enterococcus

    Streptococcus pyogenes

    Streptococcus agalactiae

    Other β-Hemolytic Streptococci

    Viridans Streptococci

    Streptococcus pneumoniae


    20. Bacillus

    Bacillus anthracis

    Bacillus cereus

    21. Listeria and Related Gram-Positive Bacteria

    Listeria monocytogenes

    Erysipelothrix rhusiopathiae

    Corynebacterium diphtheriae

    22. Mycobacterium and Related Acid-Fast Bacteria

    • Physiology and Structure of Mycobacteria

    • Mycobacterium Tuberculosis

    • Other Slow-Growing Mycobacteria

    • Rapidly Growing Mycobacteria

    • Nocardia

    • Other Weakly Acid-Fast Bacteria

    23. Neisseria and Related Genera

    Neisseria gonorrhoeae and Neisseria meningitidis

    Other Neisseria Species

    24. Haemophilus and Related Bacteria


    25. Enterobacteriaceae

    General Properties

    Escherichia coli




    Other Enterobacteriaceae

    Other General Properties

    26. Vibrio and Related Bacteria



    27. Pseudomonas and Related Bacteria



    Stenotrophomonas maltophilia



    28. Campylobacter and Helicobacter



    29. Miscellaneous Gram-Negative Rods



    Other Bordetella Species






    30. Clostridium

    Clostridium difficile

    Clostridium perfringens

    Clostridium tetani

    Clostridium botulinum

    Other Clostridial Species

    31. Non–Spore-Forming Anaerobic Bacteria

    Anaerobic Gram-Positive Cocci


    Anaerobic Gram-Positive Rods

    Anaerobic Gram-Negative Cocci

    Anaerobic Gram-Negative Rods

    32. Treponema, Borrelia, and Leptospira




    33. Mycoplasma

    Physiology and Structure

    Pathogenesis and Immunity



    Clinical Diseases

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    34. Rickettsia, Ehrlichia, and Related Bacteria




    35. Chlamydia

    Physiology and Structure

    Section 5. Virology

    36. Viral Classification, Structure, and Replication


    Virion Structure

    Viral Replication

    Viral Genetics

    Viral Vectors for Therapy

    37. Mechanisms of Viral Pathogenesis

    Basic Steps in Viral Disease

    Infection of the Target Tissue

    Viral Pathogenesis

    Viral Disease


    Control of Viral Spread

    38. Role of Viruses in Disease

    Viral Diseases

    Chronic and Potentially Oncogenic Infections

    Infections in Immunocompromised Patients

    Congenital, Neonatal, and Perinatal Infections

    39. Laboratory Diagnosis of Viral Diseases

    Specimen Collection


    Electron Microscopy

    Viral Isolation and Growth

    Detection of Viral Genetic Material

    Detection of Viral Proteins

    Viral Serology

    40. Antiviral Agents and Infection Control

    Targets for Antiviral Drugs

    Nucleoside Analogs

    Nonnucleoside Polymerase Inhibitors

    Protease Inhibitors

    Antiinfluenza Drugs


    Infection Control

    41. Papillomaviruses and Polyomaviruses

    Human Papillomaviruses


    42. Adenoviruses

    Structure and Replication

    Pathogenesis and Immunity


    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    Therapeutic Adenoviruses

    43. Human Herpesviruses

    Structure of Herpesviruses

    Herpesvirus Replication

    Herpes Simplex Virus

    Varicella-Zoster Virus

    Epstein-Barr Virus


    Human Herpesviruses 6 and 7

    Other Human Herpesviruses

    44. Poxviruses

    Structure and Replication

    Pathogenesis and Immunity


    Clinical Syndromes

    45. Parvoviruses

    Structure and Replication

    Pathogenesis and Immunity


    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    46. Picornaviruses





    47. Coronaviruses and Noroviruses



    48. Paramyxoviruses

    Structure and Replication

    Measles Virus

    Parainfluenza Viruses

    Mumps Virus

    Respiratory Syncytial Virus

    Human Metapneumovirus

    Nipah and Hendra Viruses

    49. Orthomyxoviruses

    Structure and Replication

    Pathogenesis and Immunity


    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    50. Rhabdoviruses, Filoviruses, and Bornaviruses



    Borna Disease Virus

    51. Reoviruses




    Orthoreoviruses (Mammalian Reoviruses)

    Coltiviruses and Orbiviruses

    52. Togaviruses and Flaviviruses

    Alphaviruses and Flaviviruses

    Rubella Virus

    53. Bunyaviridae and Arenaviridae



    54. Retroviruses




    Human Immunodeficiency Virus

    Human T-Cell Lymphotropic Virus and Other Oncogenic Retroviruses

    Endogenous Retroviruses

    55. Hepatitis Viruses

    Hepatitis A Virus

    Hepatitis B Virus

    Hepatitis C and G Viruses

    Hepatitis G Virus

    Hepatitis D Virus

    Hepatitis E Virus

    56. Prion Diseases

    Structure and Physiology



    Clinical Syndromes

    Laboratory Diagnosis

    Treatment, Prevention, and Control

    Section 6. Mycology

    57. Fungal Classification, Structure, and Replication

    The Importance of Fungi

    Fungal Taxonomy, Structure, and Replication

    Ascomycota (Ascomycetes)

    Basidiomycota (Basidiomycetes)

    Glomerulomycota (Mucormycetes, formerly Zygomycetes)

    Microspora (Microsporidia)

    Classification of Human Mycoses


    58. Pathogenesis of Fungal Disease

    Primary Fungal Pathogens

    Opportunistic Pathogens

    59. Role of Fungi in Disease

    60. Laboratory Diagnosis of Fungal Disease

    Clinical Recognition of Fungal Infections

    Conventional Laboratory Diagnosis

    Immunologic, Molecular, and Biochemical Markers for Direct Detection of Invasive Fungal Infections

    61. Antifungal Agents

    Systemically Active Antifungal Agents

    Topical Antifungal Agents

    Investigational Antifungal Agents

    Combinations of Antifungal Agents in the Treatment of Mycoses

    Mechanisms of Resistance to Antifungal Agents

    62. Superficial and Cutaneous Mycoses

    Superficial Mycoses

    Cutaneous Mycoses

    63. Subcutaneous Mycoses

    Lymphocutaneous Sporotrichosis


    Eumycotic Mycetoma

    Subcutaneous Entomophthoromycosis

    Subcutaneous Phaeohyphomycosis

    64. Systemic Mycoses Caused by Dimorphic Fungi



    Emergomycosis and Adiaspiromycosis



    Talaromycosis (Penicilliosis) marneffei

    65. Opportunistic Mycoses


    Opportunistic Mycoses Caused by Cryptococcus Neoformans and Other Noncandidal Yeastlike Fungi




    Mycoses Caused by Other Hyaline Molds



    66. Fungal and Fungal-Like Infections of Unusual or Uncertain Etiology



    Lacaziosis (Lobomycosis)


    Pythiosis Insidiosi



    Section 7. Parasitology

    67. Parasitic Classification, Structure, and Replication

    Importance of Parasites

    Classification and Structure

    Physiology and Replication


    68. Pathogenesis of Parasitic Diseases

    Exposure and Entry

    Adherence and Replication

    Cell and Tissue Damage

    Disruption, Evasion, and Inactivation of Host Defenses

    69. Role of Parasites in Disease

    70. Laboratory Diagnosis of Parasitic Disease

    Parasite Life Cycle as an Aid in Diagnosis

    General Diagnostic Considerations

    Parasitic Infections of the Intestinal and Urogenital Tracts

    Parasitic Infections of Blood and Tissue

    Alternatives to Microscopy

    71. Antiparasitic Agents

    Targets for Antiparasite Drug Action

    Drug Resistance

    Antiparasitic Agents

    72. Intestinal and Urogenital Protozoa

    Amebae (Amoebozoa)

    Ciliates (Metamonada [Formerly Flagellates] and Ciliophora)

    Sporozoa (Apicomplexa)

    73. Blood and Tissue Protozoa

    Plasmodium Species

    Babesia Species

    Toxoplasma gondii

    Sarcocystis lindemanni

    Free-Living Amebae



    74. Nematodes

    Enterobius vermicularis

    Ascaris lumbricoides

    Toxocara and Baylisascaris

    Trichuris trichiura


    Strongyloides stercoralis

    Trichinella spiralis

    Wuchereria bancrofti and Brugia malayi

    Loa loa

    Mansonella Species

    Onchocerca volvulus

    Dirofilaria immitis

    Dracunculus medinensis

    75. Trematodes

    Fasciolopsis buski

    Fasciola hepatica

    Clonorchis sinensis

    Paragonimus westermani


    76. Cestodes

    Taenia solium


    Taenia saginata

    Diphyllobothrium latum


    Echinococcus granulosus

    Echinococcus multilocularis

    Hymenolepis nana

    Hymenolepis diminuta

    Dipylidium caninum

    77. Arthropods




    Chelicerata (Arachnida)

    Hexapoda (Insecta)




  • 340.00 lei

    Prescribing for children is a particularly challenging discipline due to specific issues of drug absorption, metabolism, distribution and excretion. The aim of this book is to improve understanding in all aspects of paediatric prescribing, from the development of suitable drugs through to their practical administration. With its origins in the EU-funded Global Research in Paediatrics (GRiP) project this is the first truly international textbook to provide guidance on the principles behind optimal neonatal and paediatric prescribing. Harnessing the international expertise of paediatricians and pharmacists in the field, Prescribing Medicines for Children compliments the British National Formulary for Children (BNFC), facilitating translation of essential pharmacological principles into good prescribing practice. It incorporates specific information on how to promote safe and effective prescribing in paediatrics, including how to avoid medication errors and adverse drug reactions in children. Highlights include the differences in prescribing habits between countries and the shared principles that underpin rational prescribing in paediatrics and neonatology. The book is divided into two sections: Section A provides concise educational material relating to paediatric pharmacology and optimising how medicines are developed and prescribed for children. Section B considers key clinical prescribing areas and can be used as a quick reference guide. Each chapter is focused on the key issues in prescribing for a respective clinical specialty or context. Prescribing Medicines for Children is essential reading for all those who are involved in prescribing medicines to neonates and children. This includes undergraduate and postgraduate pharmacists, nurses, paediatricians and primary care physicians, academic scientists, and those working in the pharmaceutical industry and drug regulation.

  • Drugs: From Discovery to Approval 3rd Edition
    by Rick Ng
    La comanda in aproximativ 4 saptamani
    45600lei 390.00 lei

    The third edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. Concise and easy to read, Drugs: From Discovery to Approval, Third Edition quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs. The third edition incorporates the latest developments and updates in the pharmaceutical community, provides more comprehensive coverage of topics, and includes more materials and case studies suited to college and university use. Biotechnology is a dynamic field with changes across R&D, clinical trials, manufacturing and regulatory processes, and the third edition of the text provides timely updates for those in this rapidly growing field.

  • 420.00 lei

    With the range of psychotropic drugs expanding and the usages of existing medications diversifying, we are pleased to present this very latest edition of what has become the indispensable formulary in psychopharmacology. This new edition features seven new compounds as well as information about several new formulations of existing drugs. In addition, many important new indications are covered for existing drugs, as are updates to the profiles of the entire content and collection, including an expansion of the sections on long-acting injectable formulations of antipsychotics. With its easy-to-use, template-driven navigation system, The Prescriber's Guide combines evidence-based data with clinically informed advice to support everyone who is prescribing in the field of mental health.

    • Provides the most complete and up-to-date summary of the practical use of psychotropic drugs, including seven new drugs in this edition
    • Presented in a templated format, fully indexed and cross-referenced for ease of navigation
    • Written with the authority of evidence and the guidance of clinical wisdom

  • 46700lei 430.00 lei

    467 RON 430 RON

    Familiarly known as the "Orange Guide," this title is an essential reference work for all those involved in the manufacture or distribution of medicines in or for Europe. It is compiled by the UK drug regulatory body, the MHRA, and brings together the European and UK guidance documents and information on legislation relating to the manufacture and distribution of medicines for human use. It contains EU guidance on good manufacturing and good distribution practice along with relevant information on EU and UK legislation. This 2015 edition of Rules and Guidance for Pharmaceutical Manufacturers and Distributors (the Orange Guide) has been updated to incorporate changes made to Chapter 6 Quality Control of the detailed European Community guidelines on Good Manufacturing Practice (GMP) which came into operation on 1 October 2014 and the revised EU Guidelines on Good Distribution Practice.

  • 49000lei 450.00 lei

    Responding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both clinical trials and observational studies in biopharmaceutical product development. It presents the latest statistical methods for drug safety assessment. The book’s three sections focus on study design, safety monitoring, and data evaluation/analysis. The book addresses key challenges across regulatory agencies, industry, and academia. It discusses quantitative approaches to safety evaluation and risk management in drug development, covering Bayesian methods, effective safety graphics, and risk-benefit evaluation. Written by a team of experienced leaders, this book brings the most advanced knowledge and statistical methods of drug safety to the statistical, clinical, and safety community. It shares best practices and stimulates further research and methodology development in the drug safety area.

  • 470.00 lei

    Compiled by the Inspection, Enforcement and Standards Division, Medicines and Healthcare products Regulatory Agency (MHRA), London, UK

    This is the tenth edition of Rules and Guidance for Pharmaceutical Manufacturers and Distributors, compiled by MHRA. Commonly known as the Orange Guide, it remains an essential reference for all manufacturers and distributors of medicines in Europe. It provides a single authoritative source of European and UK guidance, information and legislation relating to the manufacture and distribution of human medicines.

    The new 2017 edition has been updated to incorporate changes and additions made to the detailed European Community guidelines on Good Manufacturing Practice (GMP) and the revised EU Guidelines on Good Distribution Practice (GDP), including Annexes 15 and 16.

    Comprehensive new content includes:
    • qualification of suppliers and customers
    • parallel importation and parallel distribution
    • temperature control and monitoring
    • UK legislation
    • unlicensed medicines

    There are new MHRA sections on:
    • GMP for excipients
    • guidance on revised Annex 16 of GMP
    • data Integrity definitions and guidance for industry

    Plus new Commission guidance on:
    • principles and guidelines of GMP for active substances
    • principles of GDP of active substances
    • setting health based exposure limits
    • formalised risk assessment for ascertaining the appropriate GMP for excipients.

    The work includes EU regulation on safety features for medicines, along with two Commission Q&As on the importation of active substances and safety features for medicinal products.

    A new appendix on sources of useful information has also been added.

    The Orange Guide is essential reading for anyone subject to MHRA inspection, providing you with all the answers you need to stay informed.

    It is compiled by the Inspection, Enforcement and Standards Division, MHRA, London, UK []

  • 480.00 lei

    Written by experts in the field of pharmacovigilance and patient safety, this concise resource provides a succinct, easy-to-digest overview of an increasingly critical area of medical safety. Drs. Thao Doan, Cheryl Renz, Fabio Lievano, Mondira Bhattacharya, and Linda Scarazzini provide essential information for health care professionals, clinical researchers, and regulators who need a comprehensive, up-to-date source of information on the principles and practice of pharmacovigilance.


                 Covers the evolving regulatory landscape, as well as current and future use of digital technologies.

                 Uses case studies to ensure content is relevant to everyday practice.

                 Discusses behavioral science and patient perspectives, risk communication, and new frontiers in pharmacovigilance.

                 Consolidates today’s available information on this timely topic into one convenient resource.

    Table Of Contents:


    Section I. The Regulatory Enviroment

    1. Does Regulation Drive Science or Does Science Drive Regulation?

    Section II. Data and Real World Evidence

    2. Role of Epidemiology in Pharmaceutical Industry

    3. Real World Epidemiologic Studies and Patient Registries

    Section III. Benefit-Risk in the Drug Development Life Cycle

    4. Signal Management and Methods of Signal Detection

    5. Causality Assessment and Examples of Adverse Drug Reactions (Drug Induced Liver Injury, Skin, Major Adverse Cardiac Events and Renal)

    6. Product Safety Monitoring in Clinical Trials

    7. Benefit-Risk Assessments

    8. Communicating benefit risk

    9. Pharmacovigilance and Medical Devices

    10. Vaccine Safety Surveillance

    11. Pharmacovigilance in Special Populations (Pediatrics and Elderly)

    12. Pharmacovigilance in Pregnancy

    Section IV. The Role of the Digital Revolution

    13. Impact and Implications of Technology on Pharmacovigilance

    Section V. The Next Frontier

    14. The Future of Pharmacovigilance

  • 55000lei 500.00 lei


      • Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting


      • Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting


      • Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation


      • Describes the most recent, emerging, and innovative technologies of drug delivery


      • Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies


    • Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems—crucial considerations in order to achieve licensing approval for these new technologies


    This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches.

  • 54600lei 520.00 lei



    Get the perfect blend of pharmacology, prioritization, and nursing process information. As one of the best-selling nursing pharmacology books on the market, Pharmacology and the Nursing Process focuses on the key information you need to safely and effectively administer medications. The 9th Edition features clearly written updated drug content reflecting the latest FDA drug approvals, withdrawals, and therapeutic uses. Hundreds of full-color illustrations detail how drugs work in the body and depict key steps in administration. As in previous editions, the text includes thoughtful learning strategies, simple language, a wealth of student-friendly features and innovative learning aids, and QSEN callouts. Along with its integrated NCLEX® preparation and instructor resources, you won’t find a more complete pharmacology text on the market!


    • Focus on need-to-know content uses a "key drug" approach to help you focus on the most important information.
    • Focus on the nursing process helps you learn to prioritize nursing care to focus on the most essential assessments, nursing diagnoses, interventions, and evaluation/outcome criteria.
    • Focus on prioritization includes prioritized nursing diagnoses along with corresponding prioritization of goals and outcomes, to help you learn to connect nursing diagnoses to goals and outcomes.
    • Additional QSEN coverage incorporates more QSEN information throughout the text.
        • Applicable QSEN competencies added to text case study titles
        • Collaboration and teamwork content added to selected case studies
        • Addition of new Safety: What Went Wrong? case studies
        • Explanation of QSEN initiatives as it relates to safety and quality of patient care is included in the Medication Errors chapter
    • Improved readability is aided by more friendly, direct-address language; shorter sentences; simplified language (where appropriate); and much more.
    • An extensive Photo Atlas of Drug Administration features more than 100 step-by-step illustrations depicting key steps in drug administration for various routes of drug administration.
    • UNIQUE! QSEN focus highlights those aspects of the book — such as boxes, tips, case studies, and other content — that correlate with the QSEN competencies.
    • Popular key drug approach focuses on the need-to-know content for safe clinical practice and uses a streamlined approach to drug indications, emphasizing only the most common or serious adverse effects.
    • Integrated NCLEX® Examination preparation includes seven NCLEX Examination review questions in every chapter, with at least one alternate-format item per chapter.
    • Thorough application of the nursing process is addressed in each chapter to help you learn how to prioritize nursing care to focus on the most essential assessments, nursing diagnoses, interventions, and evaluation/outcome criteria.
    • Colorful and consistent learner-friendly format utilizes a variety of tables and practical body systems organization to help you integrate pharmacology content with what you are learning in medical-surgical and adult health nursing courses.
    • Large collection of student-friendly learning aids includes approachable text elements such as:
        • Cartoon-illustrated learning strategies covering study, time management, and test-taking tips related to studying pharmacology.
        • Drug profiles highlighting specific information on commonly-used agents.
        • Case studies that help bring patients to life and promote critical thinking skills.
        • Dosages tables providing instant access to dosages, routes, and indications for individual drugs.
        • Key points summarizing key pharmacology and nursing content in each chapter.
        • Critical thinking and prioritization questions encourage you to think on a deeper level.
        • More than 250 full-color photos and illustrations show how drugs work in the body and how to administer medications safely and effectively.

    New To This Edition:

    • NEW! Thoroughly updated drug content reflects the very latest FDA drug approvals, withdrawals, and therapeutic uses, as well as corresponding updated nursing content
    • NEW! UNIQUE! Many new images in Photo Atlas of Drug Information included to accompany difficult concepts.
    • NEW! Inclusion of more student practice questions helps you better comprehend complex concepts.

    Table Of Contents:

    1. The Nursing Process and Drug Therapy
    2. Pharmacologic Principles
    3. Lifespan Considerations
    4. Cultural, Legal, and Ethical Considerations
    5. Medication Errors: Preventing and Responding
    6. Patient Education and Drug Therapy
    7. Over-the-Counter Drugs and Herbal and Dietary Supplements
    8. Gene Therapy and Pharmacogenomics
    9. Photo Atlas of Drug Administration

    10. Analgesic Drugs
    11. General and Local Anesthetics
    12. Central Nervous System Depressants and Muscle Relaxants
    13. Central Nervous System Stimulants and Related Drugs
    14. Antiepileptic Drugs
    15. Antiparkinson Drugs
    16. Psychotherapeutic Drugs
    17. Substance Use Disorder

    18. Adrenergic Drugs
    19. Adrenergic-Blocking Drugs
    20. Cholinergic Drugs
    21. Cholinergic-Blocking Drugs

    22. Antihypertensive Drugs
    23. Antianginal Drugs
    24. Heart Failure Drugs
    25. Antidysrhythmic Drugs
    26. Coagulation Modifier Drugs
    27. Antilipemic Drugs
    28. Diuretic Drugs
    29. Fluids and Electrolytes

    30. Pituitary Drugs
    31. Thyroid and Antithyroid Drugs
    32. Antidiabetic Drugs
    33. Adrenal Drugs
    34. Women’s Health Drugs
    35. Men’s Health Drugs

    36. Antihistamines, Decongestants, Antitussives, and Expectorants
    37. Respiratory Drugs

    38. Antibiotics Part 1
    39. Antibiotics Part 2
    40. Antiviral Drugs
    41. Antitubercular Drugs
    42. Antifungal Drugs
    43. Antimalarial, Antiprotozoal, and Anthelmintic Drugs
    44. Antiinflammatory and Antigout Drugs

    45. Antineoplastic Drugs Part 1: Cancer Overview and Cell Cycle–Specific Drugs
    46. Antineoplastic Drugs Part 2: Cell Cycle–Nonspecific Drugs and Miscellaneous Drugs
    47. Biologic Response–Modifying and Antirheumatic Drugs
    48. Immunosuppressant Drugs
    49. Immunizing Drugs

    50. Acid-Controlling Drugs
    51. Bowel Disorder Drugs
    52. Antiemetic and Antinausea Drugs
    53. Vitamins and Minerals
    54. Anemia Drugs
    55. Nutritional Supplements

    56. Dermatologic Drugs
    57. Ophthalmic Drugs
    58. Otic Drugs

    Appendix: Pharmaceutical Abbreviations




  • 66000lei 530.00 lei

    Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

  • 67500lei 600.00 lei



    The classic guide to driving optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines

    Presented in full color, Pharmacotherapy: A Pathophysiologic Approach, 11th Edition helps you deliver the highest-quality patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. It takes you beyond drug indications and dosages,  showing how to properly select, administer, and monitor drugs—everything you need to provide safe, effective drug therapy across all therapeutic categories. With all-new monitoring tables and authoritative content from 300 expert contributors, this new edition has been fully updated to reflect the latest evidence-based information and recommendations. You’ll find Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy.
    Why Pharmacotherapy: A Pathophysiologic Approach is perfect for students, pharmacists, and other healthcare providers:
    •  All chapters provide the most current, reliable, and relevant information available.
    •  Key concepts kick off every chapter.
    •  Clinical Presentation Tables summarize disease signs and symptoms.
    •  The majority of sections include personalized pharmacotherapy content.
    •  Clinical Controversies Boxes clarify the most complex drug therapy issues you’ll face.
    •  Diagnostic flow diagrams, treatment algorithms, dosing recommendations, and monitoring approaches have been updated in full color to distinguish treatment pathways.
    •  Most disease-oriented chapters are enhanced by updated evidence-based treatment guidelines, which often include ratings of the level of evidence to support key therapeutic approaches.
    •  Instructors who adopt this text are eligible for a PowerPoint presentation of all images and answers to Self-Assessment Questions!
    The most trusted guide of its kind for decades, Pharmacotherapy: A Pathophysiologic Approach is the go-to text for students and practitioners seeking clear, objective coverage of core pathophysiologic and therapeutic elements.

    Table of Contents:

    Section 1: Foundation Issues Updated!

    Chapter 1: The Patient Care Process Updated!

    Chapter e2: Health Literacy and Medication Use

    Chapter e3: Cultural Competency Updated!

    Chapter e4: Medication Safety Principles and Practices

    New! Chapter e5: Clinical Pharmacokinetics and Pharmacodynamics

    New! Chapter e26: Critical Care: Pain, Agitation, and Delirium

    New! Chapter e6: Pharmacogenetics

     New! Chapter e7: Clinical Toxicology

     Section 2: Common Health Problems

    Chapter e9: Pain and Headache

     Chapter e10: Minor Ophthalmic Disorders New!

    Chapter e11: Minor Otic Disorders

     Chapter e12: Cough and Other Nonspecific Respiratory Symptoms

    New! Chapter e13: Allergic Rhinitis

    Chapter e14: Oral Health and Systemic Conditions

    Chapter e15: Oral Hygiene and Minor Oral Disorders

    Chapter e16: Skin Care and Minor Dermatologic Conditions

    Chapter e17: Travel Health

     Chapter 18: Contraception Section 3: Special Populations

    New! Chapter e19: Pediatrics: General Topics in Pediatric Pharmacotherapy

    New! Chapter e20: Pediatrics: Oral Nutrition and Rehydration of Infants and Children

    Chapter e22: Geriatrics: The Aging Process in Humans and Its Effects on Physiology

    Chapter e23: Prescribing in the Older Adult

    Chapter e28: Palliative Care

    Section 4: Cardiovascular Disorders

    Chapter e29: Assessment of the Cardiovascular System Updated!

    Chapter 30: Hypertension

    Chapter 31: Dyslipidemia Updated!

    Chapter 32: Stable Ischemic Heart Disease

     Chapter 33: Acute Coronary Syndrome

    Chapter e34: Peripheral Arterial Disease

     Chapter 35: Chronic Heart Failure

    Chapter 36: Acute Decompensated Heart Failure

    Chapter 37: Venous Thromboembolism

    Chapter 38: Stroke

    Chapter 40: Cardiac Arrest

    Chapter 41: Shock Syndromes

    Section 5: Respiratory Disorders Updated!

     Chapter e42: Evaluation of Respiratory Function

    Chapter 45: Pulmonary Arterial Hypertension

    Chapter 46: Cystic Fibrosis

     Chapter e47: Drug-Induced Pulmonary Diseases

    Section 6: Gastrointestinal Disorders

    Chapter e48: Evaluation of the Gastrointestinal Tract

    Chapter 49: Gastroesophageal Reflux Disease

     Chapter 50: Peptic Ulcer Disease and Related Disorders

    Chapter 51: Inflammatory Bowel Disease

    Chapter 52: Nausea and Vomiting

    Chapter 53: Diarrhea, Constipation, and Irritable Bowel Syndrome

     Chapter 54: Portal Hypertension and Cirrhosis

     Chapter e55: Drug-Induced Liver Disease

    Chapter 56: Pancreatitis

    Chapter 57: Viral Hepatitis

    Chapter 58: Celiac Disease

    Section 7: Renal Disorders

    New! Chapter 60: Acute Kidney Injury

    New! Chapter 61: Chronic Kidney Disease Updated!

    Chapter 62: Hemodialysis and Peritoneal Dialysis Chapter 63: Drug-Induced Kidney Disease New! Chapter 64: Glomerular Diseases

    New! Chapter 65: Drug Therapy Individualization for Patients with Chronic Kidney Disease New! Chapter 66: Disorders of Sodium and Water Homeostasis

     New! Chapter 67: Disorders of Calcium and Phosphorus Homeostasis

    New! Chapter 68: Disorders of Potassium and Magnesium Homeostasis

    Section 8: Neurological Disorders

     Chapter e70: Evaluation of Neurologic Illness

    Chapter 71: Alzheimer Disease

    Chapter 72: Multiple Sclerosis

    New! Chapter 73: Epilepsy

    Chapter 75: Acute Management of the Brain Injury Patient

     Chapter 76: Parkinson Disease Updated!

    Chapter 77: Pain Management

    Chapter 78: Headache Disorders Section 9: Psychiatric Disorders Updated!

     Chapter e79: Evaluation of Psychiatric Disorders Updated!

     Chapter 80: Attention Deficit/Hyperactivity Disorder

    Chapter 81: Eating Disorders

    Chapter 82: Substance-Use Disorders: Overview of Depressants, Stimulants, and Hallucinogens Chapter 83: Substance-Related Disorders II: Alcohol, Nicotine, and Caffeine

     Chapter 84: Schizophrenia New! Chapter 85: Major Depressive Disorder

    Chapter 86: Bipolar Disorder

    Chapter 87: Anxiety Disorders: Generalized Anxiety, Panic, and Social Anxiety Disorders

     Chapter 88: Posttraumatic Stress Disorder and Obsessive-Compulsive Disorder

    Chapter 89: Sleep–Wake Disorders

    Chapter 90: Intellectual and Developmental Disabilities: Down Syndrome and Autism Spectrum Disorder

    Section 10: Endocrinologic Disorders

    Chapter 92: Thyroid Disorders

     Chapter 93: Adrenal Gland Disorders Chapter e94: Pituitary Gland Disorders

    Section 11: Gynecologic and Obsetric Disorders

    Chapter 95: Pregnancy and Lactation: Therapeutic Considerations Updated!

     Chapter 96: Menstruation-Related Disorders

     New! Chapter e102: Function and Evaluation of the Immune System

    Chapter 97: Endometriosis

    Chapter 98: Hormone Therapy in Women

    Section 12: Urological Disorders

    Chapter 99: Erectile Dysfunction

     New! Chapter 100: Benign Prostatic Hyperplasia

    Chapter 101: Urinary Incontinence

    Section 13: Immunologic Disorders

    Chapter 103: Systemic Lupus Erythematosus

    New! Chapter 105: Solid-Organ Transplantation

     Section 15: Ophthalmic Disorders

    Chapter 110: Glaucoma New!

    Chapter 111: Age-Related Macular Degeneration New!

    Chapter e112: Drug-Induced Ophthalmic Disorders

    Section 16: Dermatologic Disorders

    Chapter 113: Acne Vulgaris New!

     Chapter 115: Atopic Dermatitis

    New! Chapter 116: Alopecia

    Section 17: Hematologic Disorders

    Chapter 118: Anemias New!

    Chapter 119: Coagulation Disorders

     New! Chapter e121: Drug-Induced Hematologic Disorders

    Section 18: Infectious Diseases

    Chapter e122: Laboratory Tests to Direct Antimicrobial Pharmacotherapy

    Chapter 123: Antimicrobial Regimen Selection Chapter

     124: Central Nervous System Infections

    Chapter 125: Lower Respiratory Tract Infections

    Chapter 126: Upper Respiratory Tract Infections

    Chapter 127: Influenza

    Chapter 128: Skin and Soft-Tissue Infections

    Chapter 129: Infective Endocarditis

    Chapter 130: Tuberculosis

    Chapter 131: Gastrointestinal Infections and Enterotoxigenic Poisonings

     Chapter 132: Intra-Abdominal Infections

    Chapter e133: Parasitic Diseases

    Chapter 134: Urinary Tract Infections and Prostatitis

     Chapter 135: Sexually Transmitted Infections

    Chapter 136: Bone and Joint Infections

     Chapter 137: Sepsis and Septic Shock

    Chapter 138: Superficial Fungal Infections Updated!

    Chapter 139: Invasive Fungal Infections

    Chapter 140: Infections in Immunocompromised Patients

    Chapter 141: Antimicrobial Prophylaxis in Surgery

    Chapter 142: Vaccines and Immunoglobulins

    Chapter 143: Human Immunodeficiency Virus Infection

    Section 19: Oncologic Disorders

     New! Chapter 144: Cancer Treatment and Chemotherapy

    New! Chapter 146: Lung Cancer

    New! Chapter 147: Colorectal Cancer

    New! Chapter 148: Prostate Cancer

    New! Chapter 149: Lymphomas

    New! Chapter 151: Acute Leukemias

     New! Chapter e154: Myelodysplastic Syndromes

     New! Chapter 157: Hematopoietic Stem Cell Transplantation

    Section 20: Nutritional Disorders

    New! Chapter 158: Assessment of Nutrition Status and Nutrition Requirements

    New! Chapter 159: Parenteral Nutrition

    New! Chapter 160: Enteral Nutrition


    Top of Form

  • 72000lei 600.00 lei

    Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and inflammatory conditions. It has also been widely investigated for application in a variety of painful and non-pain inflammatory states including cancer and neurodegenerative conditions, reflecting the unique and novel properties of the drug that would never have been foreseen from knowledge of the properties when it was initially discovered.
    • Edited by leading world expert with over 40 years record in research, teaching and as a scientific advisor in the field of anti-inflammatory/analgesic agents. Professor Kim Rainsford is also the founding Editor-in-Chief of the journal, Inflammopharmacology, as well as being an Associate Editor of The Journal of Pharmacy & Pharmacology.
    • Provides a thorough coverage of the medicinal chemistry and pharmaceutics of ibuprofen, and its pharmacokinetics in both humans and animals.
    • Includes molecular, pharmacological and toxicological studies, and discusses the safety and efficacy of non-prescription ibuprofen, including its side effects. Ibuprofen: Discovery, Development & Therapeutics provides a definitive reference on all the main aspects of the chemical and pharmaceutical properties, mechanisms of action and therapeutic uses of ibuprofen including its role in the prevention and treatment of rheumatic conditions, cancer and neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases.
    The book has its origins in a volume first published in 1999, since when there have been considerable advances in research and clinical studies on ibuprofen in the treatment of many inflammatory and even non-inflammatory states. This book will prove invaluable to scientists, clinicians, pharmacists and all those who need to know about the actions and uses of anti-inflammatory and analgesic drugs.

  • 89000lei 720.00 lei

    Covering fundamentals and new developments in phytotherapy, this book combines pharmaceutical sciences and chemistry with clinical issues.
    • Helps readers better understand phytotherapy and learn the fundamentals of and how to analyze phytotherapeutic agents
    • Discusses phytotherapy in modern medicine, chemoprevention of disease, and alternatives to western medicines for specific diseases
    • Chapters summarizes the uses and applications of phytomedicines, by type like Chinese, Greco-Arab, Indian, European, and Ayurvedic
    • Includes international regulatory perspectives and discusses emerging regulations for various established and emerging markets

  • 750.00 lei


    ·         Updates the current status of gelatin and gelatin alternatives in capsule shell production

    ·         Addresses capsules as a carrier platform both for oral modified release and technologies for solving difficult drug solubility problems

    ·         Discusses modeling in support of Quality-by-Design (QbD) and capsule formulation development and manufacture

    ·         Updates the role of capsules in clinical trials based on new technologies such as miniaturization for direct "Powder in a Capsule" filling and capsule engineering

    ·         Provides practical formulation, manufacturing, and regulatory considerations in development and scale-up

    ·         Updates the latest technologies in capsule shell filling and reviews historic developments in capsule filling

    ·         Presents many topics authored by experts in the field


    Pharmaceutical Dosage Forms: Capsules covers the development, composition, and manufacture of capsules. Despite the important role that capsules play in drug delivery and product development, few comprehensive texts on the science and technology of capsules have been available for the research and academic environments. This text addresses this gap, discussing how capsules provide unique capabilities and options for dosage form design and formulation.

    Table of Contents

    1. Advances in Capsule Formulation Development and Technology

    [Larry L. Augsburger and Stephen W. Hoag]

    2. An Introduction to Two-Piece Hard Capsules and Their Marketing Benefits

    [Dennis Murachanian]

    3. Hard Shell Capsules in Clinical Trials

    [Moji Christianah Adeyeye and Amusa Adebayo]

    4. Capsule Shell Manufacture

    [Brian E. Jones, Fridrun Podczeck, and Paul Lukas]

    5. Non-Gelatin-Based Capsules

    [Sven Stegemann]

    6. Hard Shell Capsule Filling Machines

    [Donald K. Lightfoot]

    7. Instrumented Automatic Capsule Filling Machines and Filling Machine Simulation

    [Larry L. Augsburger and Vikas Moolchandani]

    8. Dry-Fill Formulation and Filling Technology

    [Pavan Heda, Vikas Agarwal, and Shailesh K. Singh]

    9. Plug Formation

    [Fridrun Podczeck]

    10. Modeling Powder Filling during Encapsulation

    [Ammar Khawam]

    11. Scale-Up and Transfer of Hard Shell Formulations across Machine Types

    [Larry L. Augsburger and Michael Levin]

    12. Modified-Release Delivery Systems: Extended-Release Capsule Platform

    [Reza Fassihi]

    13. Analytical Testing and Evaluation of Capsules

    [Stuart L. Cantor and Asish K. Dutta]

    14. Rheological Aspects of Capsule Shell Excipients and the Manufacture of Encapsulated Formulations

    [Lawrence H. Block]

    15. Quality-by-Design (QbD) for Capsule Formulation and Process Development: Regulatory Science Relevance, Scientific Case Studies, and Future Challenges

    [Huiquan Wu, Lin Xie, Stephen W. Hoag, Larry L. Augsburger, and Mansoor Khan]

  • 98200lei 900.00 lei

    As the generic pharmaceutical industry continues to grow and thrive, so does the need to conduct adequate, efficient bioequivalence studies. In recent years, there have been significant changes to the statistical models for evaluating bioequivalence. In addition, advances in the analytical technology used to detect drug and metabolite levels have made bioequivalence testing more complex. The second edition of Handbook of Bioequivalence Testing has been completely updated to include the most current information available, including new findings in drug delivery and dosage form design and revised worldwide regulatory requirements. New topics include: A historical perspective on generic pharmaceuticals New guidelines governing submissions related to bioequivalency studies, along with therapeutic code classifications Models of noninferiority Biosimilarity of large molecule drugs Bioequivalence of complementary and alternate medicines Bioequivalence of biosimilar therapeutic proteins and monoclonal antibodies New FDA guidelines for bioanalytical method validation Outsourcing and monitoring of bioequivalence studies The cost of generic drugs is rising much faster than in the past, partly because of the increased costs required for approval―including those for bioequivalence testing. There is a dire need to re-examine the science behind this type of testing to reduce the burden of development costs―allowing companies to develop generic drugs faster and at a lower expense. The final chapter explores the future of bioequivalence testing and proposes radical changes in the process of biowaivers. It suggests how the cost of demonstrating bioequivalence can be reduced through intensive analytical investigation and proposes that regulatory agencies reduce the need for bioequivalence studies in humans. Backed by science and updated with the latest research, this book is destined to spark continued debate on the efficacy of the current bioequivalence testing paradigm.

  • 1,12800lei 950.00 lei


    Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic.

    The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodologoy related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.


    Presents comprehensive reviews covering all aspects of drug development and formulation of drugs

    Now encompassing critical review chapters

    Meets the information needs of the drug development community

    Table Of Contents:

    1. Acetylcholine Hydrochloride (A.A. Al-Badr, H.A. El-Obeid).

    1.1 Physical Profile
    1.2 Analytical Profile

    2. Benazepril Hydrochloride Comprehensive Profile (F. Belal et al.).

    3. Ciprofloxacin (M.A. Al-Omar).

    3.1 Physical Profile

    3.2 Analytical Profile

    3.3 ADME Profile

    4. DipyridamoleComprehensive Profile (A. Khalil et al.).

    5. Mefenamic Acid Analytical Profile.

    6. Nimodipine (M.A. Al-Omar).

    6.1 Physical Profile

    6.2 Analytical Profile

    6.3 ADME Profile

    7. Particle Size Analysis (H.G. Brittain).


    Bottom of Form


  • Laboratory Models for Foodborne Infections
    La comanda in aproximativ 4 saptamani
    1,24000lei 1220.00 lei

     Resulting from ingestion of inappropriately prepared or stored foods containing pathogenic viruses, bacteria, fungi and parasites, foodborne infections have become a significant source of human morbidity and mortality worldwide in recent decades. This may be largely attributable to the remarkable popularity of convenient, ready-to-eat food products, the dramatic expansion of international food trades, and the continuing growth of immuno-suppressed population groups. Although anti-microbial treatments have played a crucial part in the control of foodborne infections in the past, the emergence and spread of anti-microbial resistance render the existing treatments ineffective. Additionally, our limited understanding of the molecular mechanisms of foodborne infections has thwarted our efforts in the development of efficacious vaccines for foodborne pathogens. 

    Given the obvious benefits of laboratory models in foodborne disease research, a great number of experiments have been conducted toward the elucidation of host-pathogen interactions in and pathogenic mechanisms of foodborne infections. Forming part of the Food Microbiology series, Laboratory Models for Foodborne Infections presents a state-of-the-art review of laboratory models that have proven valuable in deciphering the life cycle, epidemiology, immunobiology, and other key aspects of foodborne pathogens. 

    Written by scientists with respective expertise in foodborne pathogen research, each chapter includes a contemporary summary of a particular foodborne viral, bacterial, fungal, or parasitic infection in relation to its life cycle, epidemiology, clinical features, pathogenesis, host-pathogen interactions, and other related aspects. Besides providing a trustworthy source of information for undergraduates and postgraduates in food microbiology, Laboratory Models for Foodborne Infections offers an invaluable guide for scientists and food microbiologists with interest in exploiting laboratory models for detailed study of foodborne infections.

  • 1850.00 lei

    This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies. The main focus of this book is to review current and emerging heart failure therapies and potential targets for treatment.

  • 2,40000lei 2100.00 lei

    The Handbook of Pharmaceutical Excipients collects together essential data on the physical properties of excipients as well as providing information on their safe use and applications. All of the 400+ monographs are also thoroughly cross-referenced and indexed to allow their identification by chemical, non-proprietary or trade names. It is internationally recognised as the authoritative source of information on pharmaceutical excipients and a comprehensive guide to uses, properties and safety.

    Changes to this new edition:

    • Contains revised and updated monographs
    • 20 + new monographs including amino acids Arginine, Proline and Asparagine
    • Includes newly added Raman spectra for many excipients
    • New chapter content including information on excipients in oral solid dose formulations, and pediatric formulations

  • 2,68500lei 2400.00 lei


    • The definitive major reference work in the field, covering key information that the infectious diseases specialist will need to know about antimicrobial drugs
    • Comprehensive coverage of the drug available, including those new to the market and, importantly, those currently under trial
    • Highly standardized content, structured for ease of reference
    • Globally applicable, compiled by an international team of expert editors and contributors
    • Added to this edition - new antivirals, particularly the highly effective compounds now available to treat HIV and viral hepatitis; new antibiotics - beta-lactamase inhibitors and cephalosporins, quinolones and fluoroquinolones, anti-tuberculosis agents; plus new antifungals and antiparasitics.


    Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference.

    Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

    Table of Contents

    Foreword, Obituary: Dr. Alvis Kucers, Hail the Greats, Preface, Abbrieviations. 

    SECTION I Introduction.

    SECTION II Antibiotics: Part 1 Penicillins and related drugs, Part 2 Cephalosporins and related drugs, Part 3 Carbapenems, Part 4 Glycopeptides and lipopeptides, Part 5 Aminoglycosides, Part 6 Macrolides and Ketolides, Part 7 Tetracyclines and related drugs, Part 8 Other antibiotics, Part 9 Anti-folate agents and other synthetic antibacterials, Part 10 Nitroimidazoles, Part 11 Quinolones and Fluoroquinolones. Part 12 Anti-tuberculosis drugs.

    SECTION III Antifungal drugs: Part 1 Polyenes, Part 2 Echinocandins, Part 3 Allylamines and benzylamine derivatives, Part 4 Systemic azoles, Part 5 Topical azoles, Part 6 Topical agents—thiocarbomates, hydroxypyridones, and morpholine, Part 7 Other antifungal agents.

    SECTION IV Antiparasitic drugs: Part 1 Anti-malarial drugs, Part 2 Agents active against intestinal and extra-intestinal protozoa, Part 3 Agents active against American trypanosomiasis, Part 4 Agents active against African trypanosomiasis, Part 5 Agents active against leishmania and other pathogens, Part 6 Agents active against helminths, Part 7 Agents active against ectoparasites.

    SECTION V Antiviral drugs: Part 1 Agents active against herpesviruses, Part 2 Agents active against the human immunodeficiency virus, Part 3 Agents active against hepatitis viruses, Part 4 Agents active against influenza viruses, Part 5 Investigational antiviral drugs.

  • 3,10000lei 2500.00 lei

    A comprehensive review of the current status of antidepressants - how we arrived at this point in their evolution and where we are going in both the near and the long term. It employs both a scientific and historical approach to accomplish these goals. This volume is intended for practitioners who use antidepressants on a daily basis in their practice as well as for the student and researcher. Each will find that it provides a comprehensive and logical approach to this important group of medications. This book is being published as we mark the end of the first 50 years of the modern antidepressant era.

  • European Pharmacopoeia Supplements 9.3-9.5
    by EDQM
    La comanda in aproximativ 4 saptamani
    2900.00 lei

    The 9th edition of the European Pharmacopoeia (EP), main volume and supplements, is legally binding and details the qualitative and quantitative composition of medicines, the tests to be carried out on medicines, the raw materials used in the production of medicines and on the intermediates of synthesis.

    The EP is a single reference work for the quality control of medicines in Europe. All producers of medicines or substances for pharmaceutical use must apply the quality standards of the European Pharmacopoeia for the marketing and use of these products in Europe.


    These supplements contain all the regulatory information that will come into force in the course of 2018. They complement the 9th Edition launched last year and bring the total number of monographs to 2351 (including dosage forms), along with 361 general texts (including general monographs and methods of analysis) and around 2670 descriptions of reagents.




    · Applicable in 38 European countries and used in over 100 worldwide.

    · Delivers crucial information earlier than any other Pharmacopoeia.

    · Over 50% new or revised texts compared to the previous edition.

    · All versions (online, print and the NEW downloads) allow free access to the Knowledge Database and the online archives.





    9.3 July 2017 01 January 2018

    9.4 October 2017 01 April 2018

    9.5 January 2018 01 July 2018


  • 2950.00 lei

    The 9th Edition of the European Pharmacopoeia (EP), main volume and supplements, is legally binding and details the qualitative and quantitative composition of medicines, the tests to be carried out on medicines, the raw materials used in the production of medicines and on the intermediates of synthesis. The EP is a single reference work for the quality control of medicines in Europe. All producers of medicines or substances for pharmaceutical use must apply the quality standards of the European Pharmacopoeia for the marketing and use of these products in Europe. KEY FEATURES ? Applicable in 38 European countries and used in over 100 worldwide. ? Delivers crucial information earlier than any other Pharmacopoeia. ? Over 50% new or revised texts compared to the previous edition. ? Allows free access to the ?Knowledge? database and the online archives. PUBLICATIONS & IMPLEMENTATION DATES VOLUME PUBLICATION DATE IMPLEMENTATION DATE 9.6 July 2018 01 January 2019 9.7 October 2018 01 April 2019 9.8 January 2019 01 July 2019

  • British pharmacopoeia 2020
    La comanda in aproximativ 4 saptamani
    5,77500lei 5600.00 lei


    New, legally enforced standards, become legally effective on 1 January 2020.

    All European Pharmacopoeia texts included.


    Updated annually, the British Pharmacopoeia (BP) is the only comprehensive collection of authoritative official standards for UK pharmaceutical substances and medicinal products.

    It includes approximately 4,000 monographs which are legally enforced by the Human Medicines Regulations 2012. Where a BP monograph exists, medicinal products or active pharmaceutical ingredients sold or supplied in the UK must comply with the relevant monograph.

    All monographs and requirements of the European Pharmacopoeia (Ph. Eur.) are reproduced in the BP, making the BP a convenient and fully comprehensive set of standards that can be used across Europe and beyond.


    New for the BP 2020:


    The BP 2020 supersedes the BP 2019 and becomes legally effective on 1 January 2020. This edition incorporates new monographs from both the BP and Ph. Eur. along with a significant number of revised monographs.


    ·         35 new BP monographs, 40 new Ph. Eur monographs

    ·         331 amended BP monographs

    ·         Five new monographs for unlicensed formulations, two new monographs for herbal medicines

    ·         One new and one amended BP Veterinary monographs

    ·         All monographs from the Ph. Eur. 9th edition including Supplements 9.1 to 9.8

    ·         Three in-year online and offline download product updates to integrate the Ph. Eur. Supplements 10.0, 10.1 and 10.2.  


    The BP 2020 complete package:


    The complete package is a great value-for-money option including:

    A six-volume hard copy (printed) edition, including the BP (Veterinary) 2020

    A single-user online licence* for BP Online

    A single-user download for offline use*