Drug-Induced Liver Disease
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Editura: CRC Press
Limba: Engleza
Nr. pagini: 830
Coperta: Paperback
Dimensiuni: 17.78 x 4.32 x 25.15 cm
An aparitie: 30 Jun. 2020
Description:
Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines. This book supplies an in-depth discussion of drug-ind
Table of Contents:
PART I: MECHANISMS OF LIVER INJURY
Chapter 1. Drug-Induced Liver Disease
Chapter 2. Cytochrome P450 Activation of Toxins and Hepatoxicity
Chapter 3. Antioxidant Defense in Liver Injury: Oxidant Stress, Antioxidant Defense, and Liver Injur
Chapter 4. Hepatotxicity Due to Mitochondrial Injury
Chapter 5. Mechanisms of Cell Death and Relevance to Drug Hepatotxicity
Chapter 6. Significance of Hepatobiliary Transporters for Drug-Induced Liver Disease
Chapter 7. Immunological Mechanisms in Drug-Induced Liver Injury
Chapter 8. Mechanistic Role of Acyl Glucuronides
Chapter 9. Nonparenchymal Cells, Inflammatory Macrophages, and Hepatotxicity
Chapter 10. Role of Tissue Repair in Liver Injury
Chapter 11. Genetic Susceptibility to Drug-Induced Liver Disease
PART II: DIAGNOSIS AND MANAGEMENT
Chapter 12. Clinicapathological Patterns of Drug-Induced Liver Disease
Chapter 13. Histopathology of Drug-Induced Liver Disease
Chapter 14. Risk Factors for Drug-Induced Liver Disease
Chapter 15. Genomics, Proteomics, and Metabolomics in the Diagnosis and Mechanisms of Drug-Induced L
Chapter 16. Causality Assessment
Chapter 17. Management of the Patient with Drug-Induced Liver Disease
PART III: HEPATOTOXICITY OF SPECIFIC DRUGS
Chapter 18. Mechanisms of Acetaminophen-Induced Liver Disease
Chapter 19. Acetaminophen: Pathology and Clinical Presentation of Hepatotoxicity
Chapter 20. Mechanisms Underlying the Hepatotoxicity of Nonsteroidal Anti-inflammatory Drugs
Chapter 21. Nonsteroidal Anti-inflammatory Drugs and Leukotriene Receptor Antagonists: Pathology and
Chapter 22. Mechanism, Pathology, and Clinical Presentation of Hepatotoxicity of Anesthetic Agents
Chapter 23. Anticonvulsant Agents
Chapter 24. Hepatotoxicity of Psychotropic Drugs and Drugs of Abuse
Chapter 25. Antibacterial and Antifungal Agents
Chapter 26. Hepatotoxicity of Antituberculosis Drugs
Chapter 27. Hepatic Toxicity of Antiviral Agents
Chapter 28. Hepatotoxicity of Cardiovascular and Antidiabetic Medications
Chapter 29. Cancer Chemotherapy
Chapter 30. Hepatotoxicity of Immunomodulating Agents and the Transplant Situation
Chapter 31. Methotrexate Controversies
Chapter 32. Adverse Effects of Hormones and Hormone Antagonists on the Liver
Chapter 33. Mushroom Poisoning: A Clinical Model of Toxin-Induced Centrilobular Necrosis
Chapter 34. Hepatotoxicity of Herbal Medicines, Vitamins, and Natural Hepatotxins
Chapter 35. Occupational and Environmental Hepatotxicity
PART IV: REGULATORY PERSPECTIVES
Chapter 36. Regulatory Perspectives
Back cover
| An aparitie | 30 Jun. 2020 |
| Autor | Neil Kaplowitz , Laurie D. DeLeve |
| Dimensiuni | 17.78 x 4.32 x 25.15 cm |
| Editura | CRC Press |
| Format | Paperback |
| ISBN | 9780367446208 |
| Limba | Engleza |
| Nr pag | 830 |
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