Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships

The only book available that covers in a single volume the many agents that provoke the full range of drug-induced allergic hypersensitivities and other adverse reactions

Content is relevant to practitioners across the medical disciplines from clinicians and surgeons to nurses, pharmacists, dentists, and students

New and expanded chapters address antimicrobials, drugs used in anesthesia and surgery, a wide range of biologics, opioids, anti-cancer drugs and vaccines

About this book

The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships.  New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms.

This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies.

The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.

Reviews

“This is an essential reference for practitioners across medical disciplines from specialist clinicians, surgeons, general practitioners, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences. … It is a very helpful resource for any healthcare practitioner who is prescribing, dispensing, or administering medications and may encounter patients with drug allergy.” (Melissa M. Potts, Doody's Book Reviews, April 30, 2021)

Table of contents (16 chapters)

Scope of this Book: Adverse Reactions to Drugs and Drug Allergy

Pages 1-15

Baldo, Brian A. (et al.)

Classification and Descriptions of Allergic Reactions to Drugs

Pages 17-57

Baldo, Brian A. (et al.)

Mechanisms of Hypersensitivity

Pages 59-137

Baldo, Brian A. (et al.)

Diagnosis of Allergic Reactions to Drugs

Pages 139-181

Baldo, Brian A. (et al.)

β-Lactam Antibiotics

Pages 183-243

Baldo, Brian A. (et al.)

Other Antimicrobial Drugs

Pages 245-313

Baldo, Brian A. (et al.)

Drugs and Other Agents Used in Anesthesia and Surgery

Pages 315-409

Baldo, Brian A. (et al.)

Opioid Analgesic Drugs

Pages 411-438

Baldo, Brian A. (et al.)

Non-steroidal Anti-inflammatory Drugs

Pages 439-471

Baldo, Brian A. (et al.)

Contrast Media

Pages 473-506

Baldo, Brian A. (et al.)

Corticosteroids

Pages 507-520

Baldo, Brian A. (et al.)

Proton Pump Inhibitors

Pages 521-531

Baldo, Brian A. (et al.)

Biologics: Monoclonal Antibodies for Non-cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones

Pages 533-593

Baldo, Brian A. (et al.)

Targeted Drugs for Cancer Therapy: Small Molecules and Monoclonal Antibodies

Pages 595-644

Baldo, Brian A. (et al.)

Non-targeted Drugs for Cancer Therapy

Pages 645-682

Baldo, Brian A. (et al.)

Vaccines

Pages 683-714

Baldo, Brian A. (et al.)