HER2-Positive Breast Cancer
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Autor: Hurvitz & McCann
Editura: Elsevier
Limba: Engleza
Nr. pagini: 264
Coperta: Softcover
Dimensiuni: 19.7 x 24 cm
An aparitie: 02/08/2018
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Description: Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists. |
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Features: |
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Covers the diagnosis, treatments and targeted therapies, and management of breast cancers that are HER2-positive. Contains sections on background and testing, advanced disease, therapeutics, and toxicity considerations. Includes a timely section on innovative future therapies. |
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Table Of Contents: |
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Background/testing 1. The HER2 alteration in breast cancer 2. HER2 testing in the era of changing guidelines Advanced Disease 3. Optimal first-line treatment of HER2+ advanced disease 4. Second line therapy and beyond 5. HER2+ CNS metastases Therapeutics 6. Neoadjuvant therapy 7. Adjuvant therapy 8. Outcomes based on HR status in early stage disease 9. De-escalation of therapy for small tumor Toxicity considerations 10. Cardiac toxicity of HER2-targeted regimens 11. Non-cardiac toxicity of HER2-targeted therapy Therapies on the horizon 12. Targeting other pathways active in HER2+ disease (CDK4/6, VEGF, PI3K, mTOR, FGFR, PARP, antibody-drug conjugates, etc) 13. Harnessing the immune system in HER2+ disease 14. Biosimilars |
An aparitie | 02/08/2018 |
Autor | Hurvitz & McCann |
Dimensiuni | 19.7 x 24 cm |
Editura | Elsevier |
Format | Softcover |
ISBN | 9780323581226 |
Limba | Engleza |
Nr pag | 264 |
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