Cancer-Causing Viruses and Their Inhibitors

Description:

Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1) Hepatitis C virus (HCV) Epstein–Barr virus (EBV) Human papilloma virus (HPV) Human herpes virus 8 (HHV-8)/Kaposi’s sarcoma-associated herpes virus (KSHV) Human immunodeficiency virus (HIV/AIDS) Oncolytic viruses This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies.

Table of contents:

Chapter 1: Cancer-Causing Viruses : An Introduction

Chapter 2: Targeting Human T-Cell Leukemia Virus Type 1 : Pathogenesis and Treatment Strategies

Chapter 3: Hepatitis C Virus and Its Inhibitors : The Polymerase as a Target for Nucleoside and Nucl

Chapter 4: Mechanisms of Hepatitis C Virus Clearance by Interferon and Ribavirin Combination : Lesso

Chapter 5: Hepatitis B Virus Infection and Hepatocellular Carcinoma

Chapter 6: Epstein–Barr Virus and Treatment of Its Infection

Chapter 7: Landscape of Papillomavirus in Human Cancers : Prevention and Therapeutic Avenues

Chapter 8: Role of High-Risk Human Papillomaviruses in Breast Carcinogenesis

Chapter 9: Prospective Therapies of Genital Human Papillomavirus Infections

Chapter 10: Human Herpesvirus Type 8/Kaposi Sarcoma Herpesvirus : An Overview of Viral Pathogenesis

Chapter 11: Tea Polyphenolic Compounds against Herpes Simplex Viruses

Chapter 12: HIV Integrase Inhibitors : Qualitative and Quantitative Structure–Activity Relationshi

Chapter 13: Virus Wars : Oncolytic versus Oncogenic Viruses

Chapter 14: Oncolytic Viruses and Histone Deacetylase Inhibitors