Textbook of Autoinflammation

 Pret: 735 lei 460 lei (pret valabil pana la data de 25 septembrie 2020)

Features schematic diagrams of gene and immune system pathways involved in autoinflammatory diseases assisting the reader in understanding the genes and mechanisms involved in these diseases

Contains chapters focused on sub-specialities of the immune system as well as treatments and sequels common to many autoinflammatory diseases

Provides the reader with an in depth understanding of the currently available and potential future treatments for autoinflammation

About this Textbook

This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development.

  The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.

Table of contents (42 chapters)

Autoinflammation: Past, Present, and Future

Pages 3-15

Kastner, Daniel L.

Genetic Aspects of Investigating and Understanding Autoinflammation

Pages 19-48

Ceccherini, Isabella (et al.)

Epigenetics in Autoinflammation

Pages 49-60

Lorente-Sorolla, Clara (et al.)

Pattern Recognition Receptors in Autoinflammation

Pages 61-87

Saavedra, Victor (et al.)

Inflammasomes and Autoinflammation

Pages 89-109

Broderick, Lori

Cytokines in Autoinflammation

Pages 111-122

Rösen-Wolff, Angela (et al.)

Proteasomes in Autoinflammation

Pages 123-136

Brehm, Anja (et al.)

Disruption of Protein Homeostasis and Activation of Cellular Stress Pathways in Autoinflammation

Pages 137-147

Cudrici, Cornelia D. (et al.)

S100 Proteins in Autoinflammation

Pages 149-163

Holzinger, Dirk (et al.)

Classification of Genetically Defined Autoinflammatory Diseases

Pages 167-201

Goldbach-Mansky, Raphaela (et al.)

Clinical Approach to the Diagnosis of Autoinflammatory Diseases

Pages 203-223

Hashkes, Philip J. (et al.)

Genetic Approach to the Diagnosis of Autoinflammatory Diseases

Pages 225-237

Touitou, Isabelle (et al.)

Monitoring Disease Activity, Damage and Quality of Life

Pages 239-252

Haar, Nienke (et al.)

The Role of International Registries for Rare Autoinflammatory Diseases

Pages 253-265

Finetti, Martina (et al.)

Systemic Amyloidosis

Pages 267-289

Rezk, Tamer (et al.)

Familial Mediterranean Fever

Pages 293-313

Padeh, Shai (et al.)

Mevalonate Kinase Deficiency

Pages 315-327

Frenkel, Joost (et al.)

Tumor Necrosis Factor (TNF) Receptor-Associated Periodic Syndrome (TRAPS)

Pages 329-345

Savic, Sinisa (et al.)

Cryopyrin-Associated Periodic Syndromes (CAPS)

Pages 347-365

Hoffman, Hal M. (et al.)

Autoinflammatory Granulomatous Disease: Blau Syndrome

Pages 367-381

Rose, Carlos D. (et al.)

Very Early Onset Inflammatory Bowel Disease (VEOIBD)

Pages 383-404

Muise, Aleixo M.

Pyogenic Arthritis Pyoderma Gangrenosum and Acne (PAPA) Syndrome

Pages 405-415

Punaro, Marilynn G. (et al.)

Deficiency of Adenosine Deaminase 2 (DADA2)

Pages 417-431

Ombrello, Amanda (et al.)

Genetic Interferonopathies

Pages 433-453

Eleftheriou, Despina (et al.)

Genetic Causes of Inflammatory Bone Disease

Pages 455-470

Verbsky, James (et al.)

Pustular Forms of Psoriasis Related to Autoinflammation

Pages 471-484

Mahil, Satveer K. (et al.)

Hydatidiform Moles

Pages 485-497

Nguyen, Ngoc Minh Phuong (et al.)

Monogenic Autoinflammatory Diseases Associated with Immunodeficiency

Pages 499-514

Ombrello, Michael J.

Other Rare Monogenic Autoinflammatory Diseases

Pages 515-538

Jéru, Isabelle (et al.)

Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome

Pages 541-561

Edwards, Kathryn M. (et al.)

Chronic Non-Bacterial Osteomyelitis

Pages 563-585

Hedrich, Christian M. (et al.)

Systemic Juvenile Idiopathic Arthritis and Adult Onset Still Disease

Pages 587-616

Nigrovic, Peter A. (et al.)

Macrophage Activation Syndrome in Rheumatic Diseases

Pages 617-633

Grom, Alexei A. (et al.)

Gouty Inflammation

Pages 635-645

Schlesinger, Naomi (et al.)

Behçet Disease

Pages 647-665

Gül, Ahmet

Idiopathic Recurrent Pericarditis

Pages 667-677

Imazio, Massimo (et al.)

Schnitzler Syndrome

Pages 679-689

Koning, Heleen D. (et al.)

Autoinflammation and Autoimmunity

Pages 693-710

McGonagle, Dennis (et al.)

Interleukin-1 Mediated Autoinflammation from Heart Disease to Cancer

Pages 711-725

Dinarello, Charles A.

Colchicine

Pages 729-749

Ben-Chetrit, Eldad

Interleukin (IL)-1 Blocking Compounds and Their Use in Autoinflammatory Diseases

Pages 751-774

Kallinich, Tilmann (et al.)

Corticosteroid, Other Biologic and Small Molecule Therapies in Systemic Autoinflammatory Disorders

Pages 775-791

Lachmann, Helen J.