Foundations of Corneal Disease: Past, Present and Future

Description:

The field of cornea has seen tremendous advances over the last 40 years—this uniquely comprehensive book will discuss the history of these advances, current best practices in important diseases of the cornea and ocular surface, and examine future directions in diagnosis and management. Written by leading experts, many of whom trained under Claes Henrik Dohlman, MD, PhD, whose influence and many invaluable contributions have defined and shaped the field of cornea, each chapter will reflect the state of the art in the various aspects of cornea. Foundations of Corneal Disease: Past, Present, and Future contains six different sections, opening with an introduction which delves into the evolution of subspecialty training in cornea, and provides a historical perspective of our understanding of ocular surface disease. Section Two addresses perspectives on important corneal and external diseases including infectious keratitis, dry eye, and herpes simplex. Section Three and Section Four address surgery and surgical alternatives, and frontiers in corneal research. Section Six closes this book with a discussion of special topics: imaging the cornea, corneal blindness, eye banking, and clinical trials in dry eye, and explores future directions in this fast-paced field. Foundations of Corneal Disease: Past, Present, and Future contains is an ideal guide for corneal specialists, ophthalmology residents and fellows planning to enter cornea, corneal scientists, and to those in ophthalmology and visual science interested in a comprehensive resource on cornea and the history of this field.

Table of Contents:

Part I. Introduction & Historic Perspective

1. Reflections of a Dohlman Fellow

2. The Days of the Cornea Subspecialty: In the Beginning

3. Dry Eye Disease: A Modern History

4. Herpetic Keratitis: The Genesis of a Career in the Early Days of HSV Keratitis Research

Part II. Perspectives on Important Corneal and External Diseases

5. Fungal Keratitis

6. Ocular Herpes Simplex

7. Herpes Zoster and the Zoster Eye Disease Study (ZEDS)

8. Fuchs Endothelial Corneal Dystrophy: Rethinking an Old Disease with Insights from the Laboratory and Clinical Practice

9. Pathophysiology of Corneal Graft Rejection

10. Ocular Disease in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

11. Treatment of Chemical Burn to the Eye: A Changing Picture

12. Cicatrizing Disorders of the Ocular Surface

Part III. Surgery & Alternatives to Surgery

13. Perspectives in Keratoplasty

14. Striving for Perfect Vision: Insights from Refractive Surgery

15. The Role of Keratoprosthesis in the Treatment of Corneal Blindness

16. Corneal Crosslinking for Keratoconus and Corneal Ectasia

Part IV. Frontiers in Corneal Research

17. Claes H. Dohlman’s Legacy in Corneal Research

18. Cultivated Cells in the Treatment of Corneal Diseases

19. New Developments in Dry Eye Research

20. Novel Approaches for Restoring the Function of the Limbal Stem Cell Niche

21. Corneal Angiogenesis and Lymphangiogenesis

22. Genetics of Corneal Disease

23. The Challenge of Antibiotic Resistance in Corneal Infection

Part V. Special Topics

24. Therapeutic Contact Lenses in the Management of Corneal and Ocular Surface Disease

25. World Corneal Blindness

26. Epidemiology of Corneal Diseases

27. Eye Banking: History and Future Direction

28. Insights from Clinical Trials in Corneal Surgery

29. Clinical Trials in Dry Eye Disease: What We Have Learned and What We Still Need to Understand

30. Engaging the Next Generation in Cornea: Insights from Cornea Society University

31. Corneal Surgery in Children: Past, Present, and Future

Part VI. Closing

32. Future Directions in the Field of Cornea

Back Matter