Elastography of the Liver and Beyond

Description:

This volume explores the main applications of elastographic techniques in hepatological and gastroenterological diseases, and elaborates on the use of these diagnostic techniques in a broad range of clinical settings; in this regard, it provides a clear critical methodological approach to the correct indication, taking into account the existing diagnostic pathways, the actual diagnostic accuracy of elastographic techniques, and their impact on clinical practice in terms of correct positioning of the test in the diagnostic pathway and clinical outcomes improvement.  In the first chapters, which focus on the correct methodology for Diagnostic Accuracy Assessment of non -invasive techniques, the architecture of diagnostic research is discussed. In turn, the following sections describe a broad range of clinical applications in hepatology and gastroenterology. The closing section presents a number of case studies on practical issues, together with a critical discussion on how to promote the appropriate use of these technologies.   Given its scope, the book will be of interest to specialists, post-graduate medical students, and researchers in the fields of hepatology and gastroenterology.  

Table of Contents:

Part I. Introduction to Elastography

1. Elastographic Measures: A Methodological Approach

2. Liver Stiffness: Thresholds of Health

Part II. Liver Diseases

3. The Role of Transient Elastography for Fibrosis Staging in HCV-Related Chronic Liver Disease

4. The Role of Elastography in HBV: Assessing Liver Fibrosis

5. The Role of Transient Elastography in NAFLD

6. Elastography in Liver-Transplanted Patients

7. Elastography in Autoimmune Liver Diseases

8. Transient Elastography for the Diagnosis of Liver Fibrosis and Cirrhosis in People with Alcohol-Associated Liver Disease

9. Elastography After Treatment and During Follow-Up

10. Elastography Methods to Assess Chronic Liver Diseases: A Critical Comparison

11. The Assessment of Portal Hypertension

12. Assessing Disease Severity and Prognosis

Part III. Extrahepatic Diseases: Pancreas

13. Pancreas: Transabdominal Ultrasound-Based Elastography

14. Endoscopic Ultrasound Elastography in Pancreatic Diseases

Part IV. Extrahepatic Diseases: Bowel

15. Application of Elastography in Patients with Inflammatory Bowel Diseases

Part V. Spleen Involvement in Liver and Non-Liver Diseases

16. Liver and Spleen Stiffness in Vascular Liver Disease

17. Liver and Spleen Stiffness in Hematological Diseases

Part VI. Case Studies

18. Case 1: Unexpected High Liver Stiffness as a Warning Sign

19. Case 2: Liver and Spleen Stiffness After TIPS

20. Case 3: Congestive Hepatopathy with High Liver and Spleen Stiffness in a 17 Years Old Male Patient

21. Case 4: To Operate or Not to Operate? A Case of Crohn’s Disease When Elastography Helped