Diabetes: Epidemiology, Pathophysiology and Clinical Management
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Autor: Awanish Kumar
Editura: CRC Press
Limba: Engleza
Nr. pagini: 154
Coperta: Paperback
Dimensiuni: 15.56 x 0.89 x 23.5 cm
An aparitie: 13 Oct. 2020
Description:
Diabetes: Epidemiology, Pathophysiology and Clinical Management aims to be the one-stop diabetes book for researchers, scientists and clinicians. It details the epidemiology, causes, molecular mechanisms, molecular markers, available drugs, experimental drugs, treatment modalities, and dietary and lifestyle approaches related to diabetes. It focuses on various molecular aspects of diabetes, and its related co-morbidities. Apart from the drug-based treatment approach based on international guidelines, this book also describes various surgical treatments available for cases of uncontrolled symptomatic diabetes. It also lays emphasis on the future possibilities of different approaches for diabetes management. Key Features Includes treatment guidelines and approaches to diabetes provided by major global diabetes associations Provides a thorough and comprehensive assimilation of detailed information and updates in the field of diabetes, helpful for researchers, scientists and clinicians Contains a chapter on anti-diabetic drugs, that covers both the commercially approved drugs as well as those that are in various phases of experimental, pre-clinical, and clinical trials
Table of Contents:
Chapter 1 Diabetes Epidemiology – 1980 and Beyond
Face-to-Face with the Global Diabetes Epidemiology
References
Chapter 2 Diabetes and Inflammation
Introduction
General Mechanism of Inflammation-Induced Insulin Resistance
Macrophage Activation and Insulin Resistance in Obesity
Role of Pro-Inflammatory Cytokines in Diabetes
Tumour Necrosis Factor – α
Interleukins
C – Reactive Protein (CRP)
Toll-Like Receptors
Conclusions
References
Chapter 3 Insulin Resistance and Glucose Regulation
Introduction to Insulin Resistance
Obesity as a Cause of Insulin Resistance
Free Fatty Acids
Adiponectin
TNF-α
Resistin and Interleukin-6
Leptin
Fibroblast Growth Factor 21
Dietary Effect on Insulin Resistance
Fatty Acid Mediated Insulin Resistance
Fructose-Induced Insulin Resistance
Conclusions
References
Chapter 4 Diabetes : A Leading Contributor to Other Disease Complications
Introduction
Pathophysiology of T2DM
Diabetes-Related Complications
Diabetic Retinopathy
Cardiovascular Disorders
Diabetic Nephropathy
Diabetic Neuropathy
Pulmonary Dysfunctions
Hepatic Dysfunction
Other Complications
Periodontitis
Genito-Urinary Infections
Tuberculosis
Gastroparesis
Conclusions
References
Chapter 5 Biomarkers of Diabetes
Biomarkers
Biomarkers for T1DM
Biomarkers for T2DM
Glycated Haemoglobin (HbA1c)
1, 5-Anhydroglucitol (1,5-AG)
Uric Acid
Chromogranin A
Skin and Lens Autofluorescence
References
Chapter 6 Anti-Diabetic Drugs
Introduction
Parenteral Anti-Diabetic Drugs (Insulin)
Oral Anti-Diabetic Drugs
Drugs for Diabetes Insipidus
Drugs from the Labs: The Story of Possibilities
GK Activators
FGF21 Mimetics
PTP-1B Inhibitors
RAGE Inhibitors
References
Chapter 7 Diagnosis and Treatment
Diagnosis of Diabetes
Pharmacological Treatment of Diabetes
Surgical Treatment of Diabetes
References
Chapter 8 Dietary and Lifestyle Management of Diabetes
Importance of Dietary and Lifestyle Management in Diabetes
Metabolic Effects of Exercise
Gut Microbiome and Diabetes: Old Companion with a New Angle
References
Chapter 9 Future Prospects and Recommendations
Index
An aparitie | 13 Oct. 2020 |
Autor | Awanish Kumar |
Dimensiuni | 15.56 x 0.89 x 23.5 cm |
Editura | CRC Press |
Format | Paperback |
ISBN | 9780367544577 |
Limba | Engleza |
Nr pag | 154 |
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