Diabetes: Epidemiology, Pathophysiology and Clinical Management

Diabetes: Epidemiology, Pathophysiology and Clinical Management

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Cod produs/ISBN: 9780367544577

Disponibilitate: La comanda in aproximativ 4 saptamani

Editura: CRC Press

Limba: Engleza

Nr. pagini: 154

Coperta: Paperback

Dimensiuni: 15.56 x 0.89 x 23.5 cm

An aparitie: 13 Oct. 2020



Diabetes: Epidemiology, Pathophysiology and Clinical Management aims to be the one-stop diabetes book for researchers, scientists and clinicians. It details the epidemiology, causes, molecular mechanisms, molecular markers, available drugs, experimental drugs, treatment modalities, and dietary and lifestyle approaches related to diabetes. It focuses on various molecular aspects of diabetes, and its related co-morbidities. Apart from the drug-based treatment approach based on international guidelines, this book also describes various surgical treatments available for cases of uncontrolled symptomatic diabetes. It also lays emphasis on the future possibilities of different approaches for diabetes management. Key Features Includes treatment guidelines and approaches to diabetes provided by major global diabetes associations Provides a thorough and comprehensive assimilation of detailed information and updates in the field of diabetes, helpful for researchers, scientists and clinicians Contains a chapter on anti-diabetic drugs, that covers both the commercially approved drugs as well as those that are in various phases of experimental, pre-clinical, and clinical trials


Table of Contents:


Chapter 1 Diabetes Epidemiology – 1980 and Beyond

Face-to-Face with the Global Diabetes Epidemiology


Chapter 2 Diabetes and Inflammation


General Mechanism of Inflammation-Induced Insulin Resistance

Macrophage Activation and Insulin Resistance in Obesity

Role of Pro-Inflammatory Cytokines in Diabetes

Tumour Necrosis Factor – α


C – Reactive Protein (CRP)

Toll-Like Receptors



Chapter 3 Insulin Resistance and Glucose Regulation

Introduction to Insulin Resistance

Obesity as a Cause of Insulin Resistance

Free Fatty Acids



Resistin and Interleukin-6


Fibroblast Growth Factor 21

Dietary Effect on Insulin Resistance

Fatty Acid Mediated Insulin Resistance

Fructose-Induced Insulin Resistance



Chapter 4 Diabetes : A Leading Contributor to Other Disease Complications


Pathophysiology of T2DM

Diabetes-Related Complications

Diabetic Retinopathy

Cardiovascular Disorders

Diabetic Nephropathy

Diabetic Neuropathy

Pulmonary Dysfunctions

Hepatic Dysfunction

Other Complications


Genito-Urinary Infections





Chapter 5 Biomarkers of Diabetes


Biomarkers for T1DM

Biomarkers for T2DM

Glycated Haemoglobin (HbA1c)

1, 5-Anhydroglucitol (1,5-AG)

Uric Acid

Chromogranin A

Skin and Lens Autofluorescence


Chapter 6 Anti-Diabetic Drugs


Parenteral Anti-Diabetic Drugs (Insulin)

Oral Anti-Diabetic Drugs

Drugs for Diabetes Insipidus

Drugs from the Labs: The Story of Possibilities

GK Activators

FGF21 Mimetics

PTP-1B Inhibitors

RAGE Inhibitors


Chapter 7 Diagnosis and Treatment

Diagnosis of Diabetes

Pharmacological Treatment of Diabetes

Surgical Treatment of Diabetes


Chapter 8 Dietary and Lifestyle Management of Diabetes

Importance of Dietary and Lifestyle Management in Diabetes

Metabolic Effects of Exercise

Gut Microbiome and Diabetes: Old Companion with a New Angle


Chapter 9 Future Prospects and Recommendations



An aparitie 13 Oct. 2020
Autor Awanish Kumar
Dimensiuni 15.56 x 0.89 x 23.5 cm
Editura CRC Press
Format Paperback
ISBN 9780367544577
Limba Engleza
Nr pag 154

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