Essential Endocrinology and Diabetes, 7th Edition

Description:

Essential Endocrinology and Diabetes provides the accurate and up-to-date knowledge required for treating all areas of endocrinology and diabetes, covering the latest research, clinical guidelines, investigational methods, and therapies. This classic text explains the vital aspects of endocrine physiology in a succinct and easy-to-use format, with full-colour illustrations, clinical images, and case studies to assist readers in applying theory to practice. 

The text covers the principles of endocrinology, clinical endocrinology, and clinical diabetes and obesity, and has been revised throughout to present the most recent developments in the field. The seventh edition includes new and updated material on the latest molecular techniques, approaches to clinical investigation and diagnostics, next generation sequencing technology, and positron emission tomography (PET). The treatment of type 1 diabetes and type 2 diabetes has been updated with clinical algorithms and reflects significant advances such as incretin-based therapies, SGLT2 inhibitors, the development of better insulins, and technologies that support self-management. 

Provides students and practitioners with comprehensive and authoritative information on all major aspects of endocrine physiology 

Covers diagnosis, management, and complications of clinical disorders such as endocrine neoplasia, and type 1 diabetes and type 2 diabetes 

Explains the core principle of feedback regulation, which is vital for the correct interpretation of many clinical tests 

Features case histories, learning objectives, ‘recap’ links to chapter content, cross-referencing guides, key information boxes, and chapter summaries 

Essential Endocrinology and Diabetes, Seventh Edition is the ideal textbook for medical and biomedical students, junior doctors, and clinicians looking to refresh their knowledge of endocrine science. 

Table of Contents:

Part 1: Foundations of Endocrinology

CHAPTER 1: Overview of endocrinology

A brief history of endocrinology and diabetes

The role of hormones

Classification of hormones

Control systems regulating hormone production

Endocrine disorders

CHAPTER 2: Basic cell biology and hormone synthesis

Chromosomes, mitosis and meiosis

Synthesizing a peptide or protein hormone

Synthesizing a hormone derived from amino acids or cholesterol

Hormone transport

CHAPTER 3: Molecular basis of hormone action

Cell‐surface receptors

Nuclear receptors

CHAPTER 4: Investigations in endocrinology and diabetes

Pre‐analytical requirements for accurate endocrine testing

Laboratory assay platforms

Reference ranges

Static and dynamic testing

Cell and molecular biology as diagnostic tools

Imaging in endocrinology

Part 2: Endocrinology – Biology to Clinical Practice

CHAPTER 5: The hypothalamus and pituitary gland

Embryology and anatomy

Pituitary tumours

The hypothalamus

The hypothalamic–anterior pituitary hormone axes

The anterior pituitary hormones

Hypopituitarism

Hormones of the posterior pituitary

CHAPTER 6: The adrenal gland

The adrenal cortex

The adrenal medulla

CHAPTER 7: Reproductive endocrinology

Embryology of the reproductive organs

The male reproductive system

The female reproductive system

Pubertal disorders

Subfertility

CHAPTER 8: The thyroid gland

Embryology

Anatomy and vasculature

Thyroid hormone biosynthesis

Circulating thyroid hormones

Function of thyroid hormones

Thyroid function tests

Clinical disorders

CHAPTER 9: Calcium and metabolic bone disorders

Calcium

Hormones that regulate calcium

Clinical disorders of calcium homeostasis

Bone health and metabolic bone disease

Clinical conditions of bone metabolism

Vitamin D deficiency, osteomalacia and rickets

CHAPTER 10: Pancreatic and gastrointestinal endocrinology and endocrine neoplasia

Pancreatic endocrinology

Gastrointestinal endocrinology and associated clinical conditions

Endocrine tumour predisposition syndromes

Tumours with ectopic hormone production

Hormone‐sensitive tumours

Other tumours relevant to endocrinology

Part 3: Diabetes and Obesity

CHAPTER 11: Overview of diabetes

A brief history of diabetes and its classification

Classification of diabetes

Diagnosis of diabetes

Insulin

Glucagon

CHAPTER 12: Type 1 diabetes

What is type 1 diabetes?

Epidemiology

Pathogenesis

Aetiology

Clinical features

Diagnosis

Management of type 1 diabetes

Acute metabolic emergencies

CHAPTER 13: Type 2 diabetes

Epidemiology

Pathophysiology

Prognosis

Clinical features

Prevention of diabetes

Screening for diabetes

Management of type 2 diabetes

CHAPTER 14: Complications of diabetes

Introduction

Microvascular complications

Pathology of microvascular complications

Pathogenesis of microvascular complications

Clinical features of microvascular complications

Diabetes‐related kidney disease

Neuropathy

The diabetic foot

Genitourinary and sexual problems of diabetes

Atherosclerotic cardiovascular disease

Heart failure

Cancer

Non‐alcoholic fatty liver disease

Gastro‐intestinal tract

Bone and Joint

Skin disorders

Psychological and psychiatric sequelae of diabetes

Diabetes and pregnancy

Social sequelae of diabetes

Organization of diabetes care

CHAPTER 15: Obesity

Introduction

What is obesity?

The health and social consequences of overweight and obesity

Regulation of body weight

The causes of obesity

Genetic factors

Environmental changes

Prevention of obesity

Management of the individual with obesity

Conclusions

Index

End User License Agreement