The Drosophila Model in Cancer

The Drosophila Model in Cancer

620 Lei (TVA inclus)
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Cod produs/ISBN: 9783030236281

Disponibilitate: La comanda in aproximativ 4 saptamani

Autor: Deng, Wu-Min

Editura: Springer

Limba: Engleza

Nr. pagini: 250

Coperta: Softcover

Dimensiuni: 18.29 x 1.52 x 25.91 cm

An aparitie: 2019

 

Description:

This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics.  Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression.   Readers will discover the beauty of the fly model’s genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use.  This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems.   This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this dev

 

Table of Contents:

 

1. Drosophila Model in Cancer: An Introduction

2. Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function

3. Drosophila Models of Cell Polarity and Cell Competition in Tumourigenesis

4. Two Sides of the Same Coin – Compensatory Proliferation in Regeneration and Cancer

5. The Initial Stage of Tumorigenesis in Drosophila Epithelial Tissues

6. P53 and Apoptosis in the Drosophila Model

7. Autophagy and Tumorigenesis in Drosophila

8. Understanding Obesity as a Risk Factor for Uterine Tumors Using Drosophila

9. MicroRNAs in Drosophila Cancer Models

10. Cancer Stem Cells and Stem Cell Tumors in Drosophila

11. Drosophila as a Model for Tumor-Induced Organ Wasting

12. Drosophila melanogaster as a Model System for Human Glioblastomas

13. What Drosophila Can Teach Us About Radiation Biology of Human Cancers

14. A Drosophila Based Cancer Drug Discovery Framework

 


An aparitie 2019
Autor Deng, Wu-Min
Dimensiuni 18.29 x 1.52 x 25.91 cm
Editura Springer
Format Softcover
ISBN 9783030236281
Limba Engleza
Nr pag 250

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