Oxford Textbook of Oncology

Description:

Now in paperback, the Oxford Textbook of Oncology reflects current best practice in the multidisciplinary management of cancer, written and edited by internationally recognised leaders in the field. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.

Table of Contents:

Section 1: Hallmarks of cancer

1. The hallmarks of cancer: perspectives for cancer medicine

2. Growth factors and uncontrolled proliferation

3. Cell signalling pathways

4. Cell cycle control

5. Cancer cell death

6. Angiogenesis

7. Invasion and metastasis

8. Genetic instability

9. DNA repair after oncological therapy (radiotherapy and chemotherapy)

10. Biology of cancer and metastasis stem cells

11. Biomarker identification and clinical validation

12. Cancer, immunity, and inflammation

13. Cancer and metabolism

Section 2: Aetiology and epidemiology of cancer

14. Smoking and cancer

15. Viruses

16. Chemical carcinogens

17. Radiation-induced cancer

18. Aetiology and progression of cancer: role of body fatness, physical activity, diet, and other lifestyle factors

Section 3: Principles of oncology

19. Practice points for surgical oncology

20. Practice points for radiation oncology

21. Principles of chemotherapy

22. Multidisciplinary cancer care

23. Principles of clinical pharmacology: introduction to pharmacokinetics and pharmacodynamics

24. Design and analysis of clinical trials

25. Medical ethics in oncology

26. Health economic assessment of cancer therapy

Section 4: Population health

27. Cancer control planning

28. Cancer prevention: vaccination

29. Cancer chemoprevention

30. Population cancer screening

31. Familial cancer syndromes and genetic counselling

Section 5: Support for the cancer patient

32. Supportive and palliative care

33. Quality of life

34. Cancer survivorship and rehabilitation

Section 6: Disease orientated chapters

35. Head and neck cancer

36. Oesophageal cancer

37. Gastric cancer

38. Rectal cancer and systemic therapy of colorectal cancer

39. Colorectal cancer

40. Pancreatic cancer

41. Hepatobiliary cancers

42. Peritoneal mesothelioma

43. Cancer of the breast

44. Gynaecological cancers

45. Genitourinary cancers

46. Lung cancer

47. Neoplasms of the thymus

48. Pleural mesothelioma

49. Skin cancer: melanoma

50. Skin cancer: non-melanoma

51. Acute leukaemias

52. Chronic leukaemias

53. Myeloma

54. Malignant lymphomas

55. Sarcomas of soft tissues and bone

56. Craniospinal malignancies

57. Tumours of the eye and orbit

58. Endocrine cancers

59. Cancer of unknown primary site

Index