Textbook of Pediatric Rheumatology

Description:

Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease.

Key Features:

• Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology. 
• Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible. 
• Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today. 
• Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders. 
• Enhanced digital  version included with purchase. Your enhanced digital version allows you to access all of the text, figures, and references from the book on a variety of devices.

Table of Contens:

Cover image

Title page

Table of Contents

Copyright

Dedication

Preface

Contributors

Section I. Basic Concepts

1. Structure and Function

2. Genetics and Pediatric Rheumatic Diseases

3. Mechanistic Investigation of Pediatric Rheumatic Diseases

4. Inflammation and Its Mediators

5. Adaptive Immunity and Autoimmunity

6. Understanding Clinical Investigations

7. Clinical Outcome Measures in Pediatric Rheumatic Diseases

8. Pain and Its Assessment

9. Imaging in Pediatric Rheumatic Diseases

10. Laboratory Investigations

11. Principles in the Management of Patients with Rheumatic Disease

12. Global Issues in Pediatric Rheumatology

13. Therapeutics: Nonbiologics

14. Therapeutics: Biologics and Small Molecules

15. Nonmedical Therapies in Pediatric Rheumatic Diseases

Section II. Inflammatory Joint Disease and Related Conditions

16. Juvenile Idiopathic Arthritis: Classification and Basic Concepts

17. Systemic Juvenile Idiopathic Arthritis

18. Polyarticular Juvenile Idiopathic Arthritis

19. Oligoarticular Juvenile Idiopathic Arthritis

20. Enthesitis-Related Arthritis

21. Psoriatic Juvenile Idiopathic Arthritis

22. Uveitis in Juvenile Idiopathic Arthritis

Section III. Inflammatory Connective Tissue Disease

23. Systemic Lupus Erythematosus, Mixed Connective Tissue Disease, and Undifferentiated Connective Tissue Disease

24. Antiphospholipid Syndrome

25. Neonatal Lupus Erythematosus

26. Juvenile Dermatomyositis and Other Inflammatory Muscle Diseases

27. Juvenile Systemic Sclerosis

28. Localized Scleroderma and Eosinophilic Fasciitis

29. Sjögren Syndrome and Immunoglobulin-G4 Disease

30. Raynaud Phenomenon and Vasomotor Syndromes

Section IV. Vasculitis

31. Inflammatory Central Nervous System Disorders

32. Vasculitis and Its Classification

33. Immune Complex Small-Vessel Vasculitis: IgA Vasculitis (Henoch–Schönlein) and Hypersensitivity Vasculitis

34. Polyarteritis Nodosa

35. Kawasaki Disease

36. Antineutrophil Cytoplasmic Antibody Associated Vasculitis

37. Takayasu Arteritis and Other Vasculitides

38. Behçet Disease

Section V. Immune System Dysfunction: Autoinflammation and Immunodeficiency

39. Periodic Fever Syndromes and Other Inherited Autoinflammatory Diseases

40. Autoinflammatory Bone Diseases

41. Pediatric Sarcoidosis

42. Macrophage Activation Syndrome

43. Primary Immunodeficiencies and Rheumatic Diseases

Section VI. Infection Related Rheumatic Disorders

44. Infectious Arthritis and Osteomyelitis

45. Lyme Disease

46. Reactive Arthritis

Section VII. Rheumatic Manifestations of Non-Rheumatic Disorders

47. Skeletal Malignancies and Related Disorders

48. The Impact of Rheumatic Diseases and Their Treatment on Bone Strength Development in Childhood

49. Skeletal Dysplasias

50. Noninflammatory Musculoskeletal Pain

51. Musculoskeletal Manifestations of Inflammatory Bowel Disease

52. Musculoskeletal Manifestations of Systemic Disease

53. Pain Amplification Syndromes

54. Primary Disorders of Connective Tissue

Introduction

Index