Precision Molecular Pathology of Liver Cancer

Description:

This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC. Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma. 

Table of contents:

1. Etiology and Pathogenesis of Hepatocellular Carcinoma

2. Histologic Classification of Hepatocellular Carcinoma and Its Clinical Implications

3. Molecular Classification of Hepatocellular Carcinoma and Precision Medicine

4. Genomics Studies in Hepatocellular Carcinoma via Next-Generation Sequencing

5. Epigenetic Regulations in the Pathogenesis of HCC and the Clinical Application

6. Biomarker Discovery and Validation in HCC Diagnosis, Prognosis, and Therapy

7. Imaging of Hepatocellular Carcinoma

8. Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

9. Hepatocellular Carcinoma Metastasis and Circulating Tumor Cells

10. Immune Regulation in HCC and the Prospect of Immunotherapy

11. Liver Cell Dysplasia and the Development of HCC

12. Locoregional Therapies for Hepatocellular Carcinoma

13. The Future Prospect of Targeted Therapy in Hepatocellular Carcinoma