Molecular Pathology of Liver Diseases

Description:

Molecular Pathology of Liver Diseases integrates the traditional knowledge of physiological and pathological processes in the liver with a balanced emphasis on fundamental concepts; timely advances in cellular and molecular mechanisms; and applied pathology. The textbook is organized into several sections, each of which includes an array of chapters that progressively and cohesively elaborate on pertinent liver biology and pathology. The first three sections discuss the cellular composition of the liver along with their specialized functions, and further dissect the molecular basis of the cellular processes that are so unique to the liver. The next section examines the mechanisms that are commonly implicated in the cellular and molecular basis of several hepatic pathologies, followed eventually by a section each on a multitude of non-neoplastic and neoplastic diseases of the liver. Molecular Pathology of Liver Diseases is a comprehensive reference on liver pathobiology for basic, translational and clinical researchers and physicians The format of the volume will serve as a ready reference to relevant topics in the liver, thus providing a practical disease-based integrative resource on the molecular pathology of liver disease. Satdarshan (Paul) Singh Monga, MD is Director: Division of Experimental Pathology and Associate Professor of Pathology and Medicine, University of Pittsburgh, Pittsburgh, PA.

Table of contents (63 chapters):

Gross and Cellular Anatomy of the Liver

Pages 3-6

Tsung, Allan (et al.)

Liver Zonation

Pages 7-16

Colnot, Sabine (et al.)

Hepatocytes

Pages 17-26

Soto-Gutierrez, Alejandro (et al.)

Biliary Epithelial Cells

Pages 27-51

Mizuguchi, Yoshiaki (et al.)

Stellate Cells

Pages 53-79

Gandhi, Chandrashekhar R.

Kupffer Cells

Pages 81-95

Gandhi, Chandrashekhar R.

Sinusoidal Endothelial Cells

Pages 97-107

Stolz, Donna Beer

Hepatic Carbohydrate Metabolism

Pages 109-123

Raddatz, Dirk (et al.)

Hepatic Protein Metabolism

Pages 125-132

Lamers, Wouter H. (et al.)

Hepatic Lipid Metabolism

Pages 133-146

Huang, Jiansheng (et al.)

Detoxification Functions of the Liver

Pages 147-163

Apte, Udayan (et al.)

Bile Acid Metabolism

Pages 165-179

Chiang, John Y. L.

Liver Development

Pages 183-191

Kaestner, Klaus H.

Transcriptional Control of Hepatocyte Differentiation

Pages 193-211

Locker, Joseph

Bile Duct Development and Biliary Differentiation

Pages 213-224

Lemaigre, Frederic P.

Hepatic Progenitors in Development and Transplantation

Pages 225-241

Shafritz, David A. (et al.)

Adult Liver Stem Cells

Pages 243-260

Best, D. Hunter (et al.)

Liver Regeneration

Pages 261-278

Michalopoulos, George K.

Senescent Liver

Pages 279-290

Timchenko, Nikolai A.

Signaling Pathways in the Liver

Pages 291-306

Lade, Abigale (et al.)

Hepatocyte Transplantation

Pages 309-319

Sirbu-Boeti, Mirela-Patricia (et al.)

Hepatic Tissue Engineering

Pages 321-342

Shan, Jing (et al.)

Hepatic Gene Therapy

Pages 343-370

Nakai, Hiroyuki

Liver Cell Death

Pages 373-387

Malhi, Harmeet (et al.)

Macroautophagy

Pages 389-396

Shi, Ying-Hong (et al.)