Meningiomas

Description:

This book provides a comprehensive overview of the multidisciplinary management of meningiomas, followed by evaluation and management considerations along a spectrum of benign to more malignant behavior. It outlines the management of presumed Grade 1 tumors and how to identify features of tumors radiographically and clinically that may support a benign course rather than aggressive and vice versa. Following a stepwise progression from simple to complex, chapters introduce and tackle more aggressive meningiomas and tumor recurrence (of all Grades), with paradigms for evaluation and treatment. Tumor biology and genomics are fundamental and largely focused in the book. More recent findings which have directed personalized medicine and clinical trials are also addressed.  Meningiomas: Comprehensive Strategies for Management addresses all aspects of the evaluation and care of patients with all WHO grades of meningiomas. It is highly informative and provides clarity for a wide audience of neurosurgeons, reconstructive surgeons, oncologists, neurologists, radiation oncologists, pathologists, radiologists, residents and students who treat these patients and those who are training for a career in managing patients with these potentially challenging tumors.

Table of Contents:

Part I. Meningioma Basics

1. An Overview of Meningiomas

2. Histopathology and Grading of Meningiomas

3. Radiographic Assessment of Meningiomas

4. The Genomic Landscape of Meningiomas

Part II. Initial Meningioma Management and Treatment Paradigms

5. The Initial Evaluation and Surveillance of Meningiomas

6. Surgical Considerations for Newly Diagnosed Meningiomas

7. Endoscopic and Minimally Invasive Meningioma Surgery

8. Comprehensive Treatment Strategies for Spinal Meningiomas

9. Radiation Therapy for Low Grade Meningiomas

Part III. Treatment Options for more aggressive meningiomas

10. Low Grade Tumor Recurrence and Management of More Aggressive Meningiomas

11. Surgical Considerations for Recurrent Meningiomas

12. Radiotherapy for Aggressive Meningiomas and Recurrent Low Grade Tumors

13. The Role of Medical Therapy for Menigniomas

14. Emerging Meningioma Therapies I: Precision Medicine, Targeted Therapies, and Mutation-Specific Approaches

15. Emerging Meningioma Therapies II: Immunotherapies, Novel R