Mechanisms of Vascular Disease: A Textbook for Vascular Specialists

Description:

This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic.

Table of contents:

1. Vascular Endothelium in Health and Disease

2. Pathophysiology of Atherosclerosis

3. Mechanisms of the Vulnerable Atherosclerotic Plaque and Imaging

4. Current and Emerging Therapies for Atherosclerosis

5. Pathophysiology of Angiogenesis and Its Role in Vascular Disease

6. Vascular Biology of Smooth Muscle Cells and Restenosis

7. Vascular Haemodynamics

8. Computational Fluid Dynamics in the Arterial System: Implications for Vascular Disease and Treatment

9. Physiological Haemostasis

10. Hypercoagulable States

11. Platelets in the Pathogenesis of Vascular Disease and Their Role as a Therapeutic Target

12. Abdominal Aortic Aneurysm Pathology and Progress Towards a Medical Therapy

13. Pathophysiology and Principles of Management of Hereditary Aneurysmal Aortopathies

14. Pathophysiology, Classification and Principles of Management of Acute Aortic Syndromes

15. Biomarkers in Vascular Disease

16. Pathophysiology and Principles of Management of Vasculitis and Fibromuscular Dysplasia

17. Sepsis and Septic Shock

18. Pathophysiology of Reperfusion Injury

19. Abdominal Compartment Syndrome and Open Abdomen Treatment

20. Pathophysiology and Management of Limb Compartment Syndromes

21. Pathophysiology of Pain

22. Post Amputation Pain Syndromes

23. Treatment of Neuropathic Pain

24. Pathophysiology of Varicose Veins, Chronic Venous Insufficiency and Venous Ulceration

25. Pathophysiology of Wound Healing

26. Pathophysiology and Principles of Management of the Diabetic Foot

27. Lymphoedema

28. Graft Materials: Present and Future

29. Vascular Graft Infections

30. Radiation Physics and Biological Effects of Radiation in Vascular Surgery

31. Radiation Stewardship: Radiation Exposure, Protection and Safety in Contemporary Endovascular Practice

Back Matter