Introduction to Basics of Pharmacology and Toxicology: Volume 1: General and Molecular Pharmacology: Principles of Drug Action

Description:

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology. 

Table of Contents:

Part I. Historical Aspects of Drug Discovery

1. The Great Pharmacologists and Their Revolutionary Discoveries

2. Indian Contributions to Pharmacology

Part II. General Pharmacological Principles

3. Sources and Nature of Drugs

4. Principles and Modes of Drug Administration

5. Drug Absorption and Bioavailability

6. Drug Distribution

7. Drug Metabolism

8. Drug Elimination

9. Mechanisms of Drug Action

10. Drug Transporters

11. Adverse Effects and Pharmacovigilance

12. Drug Interactions

13. Structure-Activity Relationships

Part III. Special Topics in Pharmacology

14. Drug Information

15. Pharmacogenetics, Pharmacogenomics, and Personalized Medicine

16. Chronopharmacology

17. Pharmacoepidemiology

18. Ethnopharmacology

19. Pharmacoeconomics

20. Orphan Diseases and Drugs

21. Fixed-Dose Combinations

22. Translational and Reverse Pharmacology

23. Gene Therapy

24. Stem Cell Therapy

25. Principles of Prescription Writing

Part IV. Toxicology

26. Environmental Toxicology

27. Basic Principles of Management of Drug Poisoning

Part V. Molecular Biology in Pharmacology

28. Regulation of Gene Expression

29. Proteomics

30. Techniques Involved in Studying Receptor Dynamics

31. Polymerase Chain Reaction

32. Southern, Western and Northern Blotting

33. Antisense Oligonucleotides

34. Recombinant DNA Technology