Haematology Case Studies with Blood Cell Morphology and Pathophysiology
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Haematology Case Studies with Blood Cell Morphology and Pathophysiology

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Cod produs/ISBN: 9780128119112

Disponibilitate: La comanda in aproximativ 4 saptamani

Editura: Academic Press

Limba: Engleza

Nr. pagini: 276

Coperta: Paperback

Dimensiuni: 15.24 x 1.52 x 22.61 cm

An aparitie: 2017

 

Description:

Hematology Case Studies with Blood Cell Morphology and Pathophysiology compiles specialized case studies with specific information on various hematological disorders with Full Blood Examination (FBE or CBC), blood film images and pathophysiology of each condition. In addition, it provides basic information on how to recognize and diagnose hematological conditions that are frequently observed in the laboratory. Technicians and scientists working in core laboratories such as biochemistry labs or blood banks will find this book to be extremely thorough. Moreover, it can be used as a reference book by technicians, scientists and hematologists in every level of expertise in diagnosing hematological disorders.

Includes morphology of red cells, white cells and platelets

Provides images of actual blood slides under the microscope, showing the most important diagnostic features observed in each condition

Presents details that are considered difficult for beginners or non- hematologists, such as specific tests and techniques

Covers case studies that finish with the pathophysiology of the condition

 

Table of Contents:

 

Chapter 1: Introduction

Abstract

The Importance of the Blood Film in the Diagnosis of Haematological Disorders

Microcytic Anaemia, Haemoglobinopathies, and Blood Film Morphology

Blood Film Morphology and Diagnosis of Macrocytic Anaemia

Peripheral Blood Film and Diagnosis of Haemolytic Anaemia

Blood Film Morphology, Thrombocytopenia, and Thrombocytosis

Blood Film Morphology, Leukaemia, Lymphoma, and Bone Marrow Failure

Brief About Leukaemia

Explanations for Some Terms Used in This Booklet

Cytogenetics

Cytochemistry

Myeloperoxidase (MPO)

Sudan Black B (SBB)

Chloroacetate Esterase

Periodic Acid Schiff (PAS)

Terminal Deoxynucleotidyl Transferase Stain (TdT)

Neutrophil Alkaline Phosphatase (NAP)

Tartrate-Resistant Acid Phosphatase Stain (TRAP)

Acid Phosphatase

Alpha Naphthyl Acetate Esterase (ANAE)

Immunophenotyping

Chapter 2: Microcytic Disorders

Abstract

Case 1

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 2

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of IDA

Case 3

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Alpha Thalassemia

Case 4

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Beta Thalassemia Minor

Case 5

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Beta Thalassemia Major

Case 6

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 7

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Haemoglobin E Disease

Case 8

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Sideroblastic Anaemia

Congenital Sideroblastic Anaemias

Acquired Sideroblastic Anaemias

Chapter 3: Normocytic Disorders

Abstract

Case 9A

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Sickle Cell Anaemia

Case 9B

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Sickle Cell Disease and Thalassaemia

Case 10

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Anaemia of Chronic Disease

Case 11

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Aplastic Anaemia

Case 12

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Final Diagnosis

Chapter 4: Macrocytic Disorders

Abstract

Case 13

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Macrocytosis

Case 14

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Megaloblastic Anaemia

Case 15

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Macrocytosis Caused by Liver Disease

Chapter 5: Nonimmune Haemolytic Disorders (RBC Metabolic Abnormalities)

Abstract

Case 16

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of G6PD Deficiency

Case 17

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of PK Deficiency

Chapter 6: Nonimmune Haemolytic Disorders (RBC Membrane Abnormalities)

Abstract

Case 18

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Hereditary Spherocytosis

Case 19

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Hereditary Elliptocytosis

Case 20

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Hereditary Stomatocytosis

Case 21

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology

Case 22

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Hereditary Pyropoikilocytosis

Case 23

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of PNH

Chapter 7: Immune Haemolytic Disorders

Abstract

Case 24

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Drug-Induced Haemolytic Anaemia (DIHA)

Case 25

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Warm Autoimmune Haemolytic Anaemia (wAIHA)

Case 26

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Cold Autoimmune Haemolytic Anaemia (cAIHA)

Case 27

Clinical presentations

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnosis

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Rh-HDNB

Chapter 8: Acute Leukaemias

Abstract

Case 28

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 29

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 30

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 31

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 32

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 33

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 34

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 35

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of AML

Case 36

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of ALL

Chapter 9: Myeloproliferative/Myelodysplastic Disorders

Abstract

Case 37

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of CML

Case 38

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnoses

Differential Diagnosis

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of PV

Case 39

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Essential Thrombocythaemia

Case 40

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of MF

Case 41

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 42

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 43

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of MDS

Chapter 10: Chronic Lymphoproliferative Disorders

Abstract

Case 44

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of CLL

Case 45

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 46

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 47

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of HCL

Chapter 11: Lymphomas

Abstract

Case 48

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 49

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Mantle Cell Lymphoma

Chapter 12: Plasma Cell Disorders

Abstract

Case 50

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 51

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Plasma Cell Myeloma

Chapter 13: Haemostatic Disorders (Microangiopathic Haemolytic Anaemia)

Abstract

Case 52

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of DIC

Case 53

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Haemolytic Uremic Syndrome (HUS)

Case 54

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of TTP

Case 55

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Chapter 14: Haematological Infections

Abstract

Case 56

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of IM

Case 57

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 58

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 59

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Case 60

FBE Results

RBC Morphology

WBC Morphology

Platelet Morphology

Provisional Diagnosis

Differential Diagnoses

Further Tests and Expected Results

Final Diagnosis

Pathophysiology of Malarial Infection

Conclusion

References

 


An aparitie 2017
Autor Indu Singh Professor, Alison Weston, Avinash Kundur, Gasim Dobie
Dimensiuni 15.24 x 1.52 x 22.61 cm
Editura Academic Press
Format Paperback
ISBN 9780128119112
Limba Engleza
Nr pag 276

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