Haematology Case Studies with Blood Cell Morphology and Pathophysiology
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Editura: Academic Press
Limba: Engleza
Nr. pagini: 276
Coperta: Paperback
Dimensiuni: 15.24 x 1.52 x 22.61 cm
An aparitie: 2017
Description:
Hematology Case Studies with Blood Cell Morphology and Pathophysiology compiles specialized case studies with specific information on various hematological disorders with Full Blood Examination (FBE or CBC), blood film images and pathophysiology of each condition. In addition, it provides basic information on how to recognize and diagnose hematological conditions that are frequently observed in the laboratory. Technicians and scientists working in core laboratories such as biochemistry labs or blood banks will find this book to be extremely thorough. Moreover, it can be used as a reference book by technicians, scientists and hematologists in every level of expertise in diagnosing hematological disorders.
Includes morphology of red cells, white cells and platelets
Provides images of actual blood slides under the microscope, showing the most important diagnostic features observed in each condition
Presents details that are considered difficult for beginners or non- hematologists, such as specific tests and techniques
Covers case studies that finish with the pathophysiology of the condition
Table of Contents:
Chapter 1: Introduction
Abstract
The Importance of the Blood Film in the Diagnosis of Haematological Disorders
Microcytic Anaemia, Haemoglobinopathies, and Blood Film Morphology
Blood Film Morphology and Diagnosis of Macrocytic Anaemia
Peripheral Blood Film and Diagnosis of Haemolytic Anaemia
Blood Film Morphology, Thrombocytopenia, and Thrombocytosis
Blood Film Morphology, Leukaemia, Lymphoma, and Bone Marrow Failure
Brief About Leukaemia
Explanations for Some Terms Used in This Booklet
Cytogenetics
Cytochemistry
Myeloperoxidase (MPO)
Sudan Black B (SBB)
Chloroacetate Esterase
Periodic Acid Schiff (PAS)
Terminal Deoxynucleotidyl Transferase Stain (TdT)
Neutrophil Alkaline Phosphatase (NAP)
Tartrate-Resistant Acid Phosphatase Stain (TRAP)
Acid Phosphatase
Alpha Naphthyl Acetate Esterase (ANAE)
Immunophenotyping
Chapter 2: Microcytic Disorders
Abstract
Case 1
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 2
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of IDA
Case 3
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Alpha Thalassemia
Case 4
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Beta Thalassemia Minor
Case 5
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Beta Thalassemia Major
Case 6
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 7
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Haemoglobin E Disease
Case 8
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Sideroblastic Anaemia
Congenital Sideroblastic Anaemias
Acquired Sideroblastic Anaemias
Chapter 3: Normocytic Disorders
Abstract
Case 9A
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Sickle Cell Anaemia
Case 9B
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Sickle Cell Disease and Thalassaemia
Case 10
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Anaemia of Chronic Disease
Case 11
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Aplastic Anaemia
Case 12
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Final Diagnosis
Chapter 4: Macrocytic Disorders
Abstract
Case 13
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Macrocytosis
Case 14
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Megaloblastic Anaemia
Case 15
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Macrocytosis Caused by Liver Disease
Chapter 5: Nonimmune Haemolytic Disorders (RBC Metabolic Abnormalities)
Abstract
Case 16
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of G6PD Deficiency
Case 17
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of PK Deficiency
Chapter 6: Nonimmune Haemolytic Disorders (RBC Membrane Abnormalities)
Abstract
Case 18
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Hereditary Spherocytosis
Case 19
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Hereditary Elliptocytosis
Case 20
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Hereditary Stomatocytosis
Case 21
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology
Case 22
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Hereditary Pyropoikilocytosis
Case 23
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of PNH
Chapter 7: Immune Haemolytic Disorders
Abstract
Case 24
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Drug-Induced Haemolytic Anaemia (DIHA)
Case 25
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Warm Autoimmune Haemolytic Anaemia (wAIHA)
Case 26
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Cold Autoimmune Haemolytic Anaemia (cAIHA)
Case 27
Clinical presentations
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnosis
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Rh-HDNB
Chapter 8: Acute Leukaemias
Abstract
Case 28
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 29
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 30
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 31
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 32
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 33
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 34
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 35
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of AML
Case 36
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of ALL
Chapter 9: Myeloproliferative/Myelodysplastic Disorders
Abstract
Case 37
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of CML
Case 38
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnoses
Differential Diagnosis
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of PV
Case 39
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Essential Thrombocythaemia
Case 40
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of MF
Case 41
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 42
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 43
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of MDS
Chapter 10: Chronic Lymphoproliferative Disorders
Abstract
Case 44
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of CLL
Case 45
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 46
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 47
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of HCL
Chapter 11: Lymphomas
Abstract
Case 48
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 49
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Mantle Cell Lymphoma
Chapter 12: Plasma Cell Disorders
Abstract
Case 50
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 51
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Plasma Cell Myeloma
Chapter 13: Haemostatic Disorders (Microangiopathic Haemolytic Anaemia)
Abstract
Case 52
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of DIC
Case 53
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Haemolytic Uremic Syndrome (HUS)
Case 54
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of TTP
Case 55
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Chapter 14: Haematological Infections
Abstract
Case 56
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of IM
Case 57
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 58
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 59
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Case 60
FBE Results
RBC Morphology
WBC Morphology
Platelet Morphology
Provisional Diagnosis
Differential Diagnoses
Further Tests and Expected Results
Final Diagnosis
Pathophysiology of Malarial Infection
Conclusion
References
An aparitie | 2017 |
Autor | Indu Singh Professor, Alison Weston, Avinash Kundur, Gasim Dobie |
Dimensiuni | 15.24 x 1.52 x 22.61 cm |
Editura | Academic Press |
Format | Paperback |
ISBN | 9780128119112 |
Limba | Engleza |
Nr pag | 276 |
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