Greenberger’s CURRENT Diagnosis & Treatment Gastroenterology, Hepatology, & Endoscopy, Fourth Edition

 

Description:

The peerless guide to clinical management of digestive and liver diseases—updated to reflect the latest research and treatments Authoritative coverage of the entire spectrum of gastroenterology and hepatology conditions, including therapeutic advances in Barrett’s esophagus, eosinophilic esophagitis, acute diarrheal disorders, peptic ulcer disease, hereditary gastrointestinal cancer syndromes, upper and lower gastrointestinal bleeding Written by expert faculty physicians at Harvard Medical School and Brigham and Women's Hospital Presented in a streamlined style that makes learning and retaining key information effortless More than 90 full-color endoscopic and radiographic images enhance clinical decision-making and clarify imaging techniques Logical organization begins with a section on general concerns such as acute abdominal pain, then progresses to specific disease categories “Essentials of Diagnosis” bulleted lists deliver instant guidance on identifying both common and rare digestive disorders Updated references to recently-published clinically relevant articles Key information from related fields, including gastrointestinal surgery, and subspecialties such as liver transplantation, advanced endoscopy, bariatric surgery, inflammatory bowel disease, mast cell disease, toxicities of oncologic therapy, intestinal malabsorption, nutrition, and state of the art imaging High-yield overview of effective treatment approaches for both acute and chronic viral hepatitis provides key perspectives on improving patient outcomes

 

 

Table of Contents:

 

 

 

Section I. General Concerns

 

1. Acute Abdominal Pain: Basic Principles & Current Challenges

Evaluation of the Acute Abdomen

Acute Appendicitis

Unique Presentations of Appendicitis

2. Inflammatory Bowel Disease: Immunologic Considerations & Therapeutic Implications

General Principles of Gut-Associated Lymphoid Tissues and the Mucosal Immune Response

Pathogenesis of Inflammatory Bowel Disease

Mucosal Inflammatory Signatures of IBD

Cytokines in IBD and Therapeutic Implications

Additional Therapeutic Targets in IBD

3. Inflammatory Bowel Disease: Medical Considerations

General Considerations

Epidemiology

Etiology

Clinical Findings

Radiographic Findings

Endoscopic Examination

Extraintestinal Manifestations

Complications

Differential diagnosis of IBD

Medical Therapy of Crohn’s Disease and Ulcerative Colitis

Treatment of Acute Inflammation

Cyclosporine and Tacrolimus

Surgical Management of IBD

4. Inflammatory Bowel Disease: Surgical Considerations

Ulcerative Colitis

Crohn’s Disease

5. Acute Diarrheal Disorders

Acute Diarrhea

Acute Diarrheal Disease Caused by Specific Infections

6. Mesenteric Vascular Disease

Mesenteric Ischemia

Acute Mesenteric Ischemia

Chronic Mesenteric Ischemia

Acute Colonic Ischemia

7. Gastrointestinal & Biliary Complications of Pregnancy

Gastroesophageal Reflux Disease

Nausea & Vomiting

Hyperemesis Gravidarum

Constipation

Diarrhea

Hemorrhoids

Irritable Bowel Syndrome

Fecal Incontinence

Inflammatory Bowel Disease

Abdominal Pain

Peptic Ulcer Disease

Biliary Disease

Pancreatitis

Appendicitis

Intestinal Obstruction, Pseudo-Obstruction, & Gastrointestinal Cancer

Endoscopy In Pregnancy

8. Liver Disease in Pregnancy

Interpretation of Liver Biochemical Tests During Pregnancy

Hepatic Conditions Unique to Pregnancy

Conditions Not Unique to Pregnancy

9. State-of-the-Art Imaging of the Gastrointestinal System

Gastrointestinal Tract Imaging

Liver Imaging

Biliary Imaging

Pancreatic Imaging

Summary of Current Recommendations

10. Acute and Chronic Gastrointestinal Toxicities of Oncologic Therapy

Acute Complications

Chronic Gastrointestinal Complications

11. Mast Cell Disorders

General Considerations

Classifications of Mast Cell Disorders

Pathogenesis of Mast Cell Disorders

Clinical Findings

Differential Diagnosis

Treatment

Clinical Course & Prognosis

Unresolved Issues

Section II. Esophageal Diseases

12. Gastroesophageal Reflux Disease

General Considerations

Clinical Findings

Complications

Treatment

Course & Prognosis

13. Barrett Esophagus

General Considerations

Clinical Findings

Treatment

Course & Prognosis

14. Oropharyngeal & Esophageal Motility Disorders

Oropharyngeal Dysphagia

Impaired Ues Relaxation, Cricopharyngeal Spasms, & Cricopharyngeal Bar

Zenker Diverticulum

Globus Pharyngeus

Esophageal Motility Disorders

Esophageal Motor Dysphagia

Gastroesophageal Reflux Disease

Esophageal Chest Pain

Disorders of Inhibitory Innervation

Disorders of Excitatory Nerves and Smooth Muscles

15. Eosinophilic Esophagitis

General Considerations

Epidemiology

Pathogenesis

Clinical Findings

Differential Diagnosis

Treatment

Course & Prognosis

Unresolved Issues

Section III. Diseases of the Stomach

16. Peptic Ulcer Disease

General Considerations

Pathogenesis

Clinical Findings

Differential Diagnosis

Complications

Treatment

17. Zollinger-Ellison Syndrome (Gastrinoma)

General Considerations

Pathogenesis

Classification

Clinical Findings

Treatment

Prognosis

18. Functional Dyspepsia

General Considerations

Pathogenesis

Clinical Findings

Differential Diagnosis

Treatment

Course & Prognosis

19. Disorders of Gastric & Small Bowel Motility

Gastroparesis & Chronic Intestinal Pseudo-Obstruction

Dumping Syndrome & Accelerated Gastric Emptying

Rapid Transit Dysmotility of the Small Bowel

20. Acute Upper Gastrointestinal Bleeding

Nonvariceal Bleeding

Less Common Causes of Nonvariceal Bleeding

Variceal Bleeding

Section IV. Small Bowel Diseases

21. Intestinal Malabsorption & Nutrition

Diseases Associated with Intraluminal Maldigestion

Diseases Associated with Impaired Mucosal Digestion & Absorption

Diseases Caused by Impairment of both Intraluminal Digestion & Mucosal Digestion/Absorption

Diseases Caused by Impaired Postmucosal Transport

Section V. Colorectal Diseases

22. Chronic Constipation & Fecal Incontinence

Chronic Constipation

Fecal Incontinence

23. Diverticular Disease of the Colon

Diverticulosis

Acute Diverticulitis

Diverticular Hemorrhage

24. Colorectal Cancer Screening

Risk Stratification

Screening & Surveillance Recommendations

Screening Modalities

Additional Screening Modalities

Summary of Recommendations

25. Hereditary Gastrointestinal Cancer Syndromes

Hereditary Colorectal Cancer Syndromes

Hamartomatous Polyposis Syndromes

Serrated Polyposis Syndrome

Colorectal Polyposis Not Otherwise Specified

Other Gastrointestinal Cancer Syndromes

26. Irritable Bowel Syndrome

General Considerations

Pathogenesis

Clinical Findings

Differential Diagnosis

Complications

Treatment

27. Acute Lower Gastrointestinal Bleeding

Evaluation of Lower GI Bleeding

Specific Causes of Acute Lower GI Bleeding

Section VI. Pancreatic Diseases

28. Acute Pancreatitis

General Considerations

Pathogenesis

Clinical Findings

Differential Diagnosis

Treatment

Prognosis

29. Chronic Pancreatitis

General Considerations

Pathogenesis

Clinical Findings

Differential Diagnosis

Complications

Treatment

Course & Prognosis

30. Autoimmune Pancreatitis

General Considerations

Type 1 Autoimmune Pancreatitis

Epidemiology

Clinical Findings

Type 2 Autoimmune Pancreatitis

Diagnosis & Differential Diagnoses

Treatment

Course & Prognosis

31. Tumors of the Pancreas

Pancreatic Cancer

Cystic Neoplasms of the Pancreas

Pancreatic Lymphoma

Section VII. Therapeutic Endoscopy & Diagnostic Techniques

32. Polypectomy

Equipment

Polypectomy for Sessile Polyps

Polypectomy for Pedunculated Polyps

Endoscopic Mucosal Resection

Endoscopic Submucosal Dissection

Endoscopic Full-Thickness Resection

33. Endoscopic Management of Acute Biliary & Pancreatic Conditions

Acute Cholangitis

Gallstone Pancreatitis

Bile Duct Injuries

Pancreatic Duct Injuries

Hemorrhagic Biliary & Pancreatic Conditions

34. Endoscopic Retrograde Cholangiopancreatography (ERCP)

Disorders of the Major Duodenal Papilla

Biliary System

Pancreas

35. Video Capsule Endoscopy & Deep Small Bowel Enteroscopy

Video Capsule Endoscopy

Deep Small Bowel Enteroscopy

36. Gastrointestinal Foreign Bodies

General Considerations

Clinical Findings

Treatment

37. Endoscopic Ultrasound

Cancer Staging

Nonmalignant Lesions

Therapeutic Endoscopic Ultrasound

Future Directions

38. Endoscopic & Surgical Treatment of Obesity

Treatment of Obesity

Endoscopic Bariatric & Metabolic Therapies

Metabolic Surgery

Metabolic Surgical Procedures

Postoperative Care & Complications

Gastroenterology Evaluation & Treatment

Long-Term Outcomes of Metabolic Surgery

Weight Regain

Recommendations & Caveats

Section VIII. Liver Diseases

39. Approach to Abnormal Liver Tests

General Considerations

Pathogenesis

Prevention

Clinical Findings

Differential Diagnosis

Complications

Treatment

Prognosis

When to Refer & Admit

40. Acute Liver Failure

Specific Causes of Acute Liver Failure

41. Viral Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

42. Autoimmune Liver Disorders

Autoimmune Hepatitis

Primary Biliary Cholangitis

43. Metabolic Liver Diseases

Hemochromatosis

Wilson Disease

α1-Antitrypsin Deficiency

44. Alcohol-Associated Liver Disease

General Considerations

Pathogenesis

Clinical Findings

Differential Diagnosis

Treatment

Alcohol-associated Hepatitis

45. Nonalcoholic Fatty Liver Disease

General Considerations: Definitions

Pathogenesis

Clinical Findings

Treatment

Course & Prognosis

46. Complications of Cirrhosis: Ascites & Hepatic Encephalopathy

Introduction

General Considerations

Ascites

Hepatic Encephalopathy

47. Portal Hypertension & Esophageal Variceal Hemorrhage

Gastric Varices

Portal Hypertensive Gastropathy

Idiopathic Portal Hypertension

Future Treatment Trends

48. Drug-Induced Liver Injury

Drugs of Special Interest

49. Liver Neoplasms

Benign Liver Tumors

Hepatocellular Carcinoma

Cholangiocarcinoma

Metastatic Liver Disease

50. Liver Transplantation

Indications for Transplantation

Pretransplant Evaluation

Contraindications

Listing & Donor Liver Options

Transplantation Procedures

Complications

Infection after Liver Transplantation

Long-Term Medical Care After Liver Transplantation

Prognosis & Disease Recurrence

Section IX. Biliary Tract Diseases

51. Primary Sclerosing Cholangitis & Congenital Disorders of the Biliary System

General Considerations: Primary Sclerosing Cholangitis

Pathogenesis

Clinical Findings

Differential Diagnosis

Treatment

Course & Prognosis

General Considerations: Congenital Cystic Diseases of the Biliary System

Pathogenesis

Classification

Clinical Findings

52. Gallstone Disease

General Considerations

Pathogenesis

Clinical Features

Differential Diagnosis

Complications

Treatment

Index

Color insert appears between pages 400 and 401.

 

An aparitie	06 Jul 2022
Autor	Sonia Friedman, John Saltzman, Richard Blumberg, Norton Greenberger
Dimensiuni	18.42 x 2.54 x 22.86 cm
Editura	McGraw-Hill
Format	Paperback
ISBN	9781260473438
Limba	Engleza
Nr pag	704