Theranostics Approaches to Gastric and Colon Cancer

Description:

This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer.  The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.

Table of Contents:

1. Therapeutic Role of Phytochemicals in Colorectal Cancer

2. Adiponectin Signaling in Colorectal Cancer

3. Role of Matrix Metalloproteinases in Colorectal Cancer

4. The Role of Hypoxia-Inducible Factor 1-Alpha in Colorectal Cancer

5. Mechanisms and Pathways of Metabolic Reprogramming of Colorectal Cancer

6. Targeting Metabolic Reprogramming of Colorectal Cancer

7. Understanding Colorectal Cancer: The Basics

8. Molecular Signaling Pathways Involved in Gastric Cancer Chemoresistance

9. Meta-Analysis Reveals no Significant Association of EPHX1 Tyr113His and His139Arg Polymorphisms with the Colorectal Cancer Risk

10. Meta-Analysis of Genetic Variants in Alcohol Metabolizing Enzymes and their Association with Colorectal Cancer Risk

11. Gut Microbiota as Signatures in Non-communicable Diseases and Mucosal Immunity

12. Immunotherapy for Colon Cancer: Recent Perspectives

13. Nanotechnology Applications in Gastric Cancer