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The American Psychiatric Association Publishing Textbook of Psychopharmacology, Sixth Edition
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Limba: Engleza
Nr. pagini: 1975
Coperta: Hardcover
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An aparitie: 14 May 2024
More than 160 authors—including more than 75 new contributors—lent their expertise to this sixth edition of The American Psychiatric Association Publishing Textbook of Psychopharmacology. Featuring 12 all-new chapters and fully aligned with the revised DSM-5-TR classification, this two-volume text offers an unrivaled, in-depth look at the rapidly evolving field of neuropsychopharmacology.
The opening chapters provide a whirlwind tour of the multiple disciplines that undergird the chapters to come, with topics extending from the principles of molecular biology and genomics to the rudiments of neuroimaging and personalized medicine in psychiatry. The main body of the Textbook features an examination of the medication classes that form the basis of psychopharmacological treatment. For each drug within a class, data are reviewed on history and discovery, preclinical and clinical pharmacology, pharmacokinetic parameters, mechanism of action, indications and efficacy, side effects and toxicology, and drug-drug interactions. The Textbook's second volume focuses on psychopharmacological approaches to treatment of patients with major psychiatric disorders (e.g., mood and anxiety disorders, schizophrenia, substance use disorders) as well as patients in specific populations (e.g., adults with ADHD, pediatric patients). For each specific condition, patient population, or setting, chapters provide guidance on topics such as medication selection, combination and maintenance dosing regimens, side-effect monitoring and management, and optimization of treatment response. Closing this volume is an Appendix of Psychiatric Medications with key information on each of the agents covered in the Textbook, presented in a convenient tabular format.
Noteworthy additions to this textbook include chapters addressing the following topics:
• The potential roles of personalized medicine in psychiatry and of artificial intelligence and machine learning in psychopharmacology• New medications with novel pharmacological mechanisms, including the neurosteroid antidepressant brexanolone and the atypical antipsychotic pimavanserin• Use of investigational agents, such as psychedelics, in psychiatric treatment• Treatment of alcohol use disorder, PTSD, OCD, and autism spectrum disorder• Treatment of ADHD in adults• Treatment of women in all life phases, including during pregnancy and the postpartum period• Treatment of individuals with intellectual developmental disorder
With a level of detail not found in any other source, this new edition of The American Psychiatric Association Publishing Textbook of Psychopharmacology illuminates the path to effective evidence-based practice of psychopharmacology for novice and seasoned clinicians alike.
Table of Contents:
PART I Principles of Pharmacology
1 Basic Principles of Molecular Biology and Genomics
2 Neurotransmitters, Receptors, and Transporters
3 Genetics and Epigenetics
4 Psychoneuroendocrinology
5 Brain–Immune System Interactions
6 Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics
Appendix: Pharmacokinetic Parameters of Specific Medications
7 Neuroimaging and Psychiatry
8 Personalized Medicine in Psychiatry
9 Machine Learning in Psychopharmacology
PART II Classes of Psychiatric Treatments
Antidepressants and Anxiolytics
10 Monoamine Oxidase Inhibitors
11 Tricyclic and Tetracyclic Drugs
12 Fluoxetine and Fluvoxamine
13 Sertraline and Paroxetine
14 Citalopram and Escitalopram
15 Trazodone and Nefazodone
16 Vortioxetine
17 Mirtazapine
18 Bupropion
19 Venlafaxine and Desvenlafaxine
20 Duloxetine, Milnacipran, and Levomilnacipran
21 Ketamine and Esketamine
22 Benzodiazepines
23 Buspirone
24 Brexanolone and Other Neurosteroids
Antipsychotics
25 Classic Antipsychotic Medications
26 Clozapine
27 Olanzapine
28 Quetiapine
29 Risperidone and Paliperidone
30 Aripiprazole and Brexpiprazole
31 Ziprasidone and Asenapine
32 Iloperidone
33 Lurasidone
34 Cariprazine
35 Pimavanserin
36 Management of Psychiatric Medication–Induced Movement Disorders
Drugs for Treatment of Bipolar Disorder
37 Lithium
38 Valproate
39 Carbamazepine, Oxcarbazepine, and Eslicarbazepine
40 Gabapentin and Pregabalin
41 Lamotrigine
42 Topiramate
Other Agents
43 Agents for Neurocognitive Disorders
44 Sedative-Hypnotics
45 Psychostimulants and Wakefulness-Promoting Agents
46 Electroconvulsive Therapy and Other Neuromodulation Therapies
47 Psychedelic Drugs as Treatments in Psychiatry
Index
Figure Color Plates
Volume II Contents
Contributors
Introduction
PART III Psychopharmacological Treatment
48 Treatment of Depression
49 Treatment of Bipolar Disorder
50 Treatment of Anxiety Disorders
51 Treatment of Posttraumatic Stress Disorder
52 Treatment of Obsessive-Compulsive Disorder …
53 Treatment of Schizophrenia
54 Treatment of Substance Use Disorders
55 Treatment of Alcohol Use Disorder
56 Treatment of Personality Disorders
57 Treatment of Eating Disorders
58 Treatment of Insomnia
Appendix: Properties of Agents Commonly Used to Treat Insomnia
59 Treatment of Chronic Pain
60 Treatment of Child and Adolescent Disorders
Appendix: Psychotropic Medications Commonly Prescribed for Children and Adolescents
61 Treatment During Late Life
62 Treatment of Women Excluding Pregnancy and Postpartum
63 Psychopharmacology During Pregnancy and Lactation
64 Treatment of Attention-Deficit/Hyperactivity Disorder in Adults
65 Treatment of Individuals With Intellectual Developmental Disorder
66 Treatment of Autism Spectrum Disorder
Appendix: Outcome Measures for Assessment of Core Symptom Domains in Autism Spectrum Disorder
67 Treatment of Psychiatric Emergencies
Appendix of Psychiatric Medications
Index
An aparitie | 14 May 2024 |
Autor | Alan F. Schatzberg, M.D, Ph.D. Charles B. Nemeroff, M.D |
Editura | American Psychiatric Association Publishing |
Format | Hardcover |
ISBN | 9781615374359 |
Limba | Engleza |
Nr pag | 1975 |
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