Speroff’s Clinical Gynecologic Endocrinology and Infertility

 One of the world's most widely read gynecology texts for nearly 50 years, Speroff’s Clinical Gynecologic Endocrinology and Infertility provides a complete explanation of the female endocrine system and offers practical guidance for evaluation and treatment of common disorders. In this fully revised ninth edition, the editorial and author team from Yale School of Medicine have assumed the reins of Dr. Speroff’s landmark work, retaining the clear, concise writing style and illustrations that clarify and explain complex concepts.

This classic text remains indispensable for students, residents, and clinicians working in reproductive endocrinology and infertility, bringing readers up to date with recent advances that have occurred in this fast-changing field.

• Remains the definitive text on reproductive endocrinology, offering authoritative coverage of reproductive physiology, clinical endocrinology, contraception, and infertility.
• Contains two new chapters on transgender medicine and fertility preservation.
• Features many full-color illustrations, algorithms, and tables throughout.
• Retains Dr. Speroff’s clear, user-friendly writing style while ensuring content is up to date with today’s best clinical practices.

 
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Table of Contents:

Cover

Title Page

Copyright

Dedication

Contributors

Foreword

Preface

Acknowledgments

Contents

PART 1 Foundations of Pediatric and Adolescent Gynecology

1 Office Evaluation of the Child and Adolescent

OFFICE EVALUATION OF THE CHILD

OBTAINING THE HISTORY

GYNECOLOGIC EXAMINATION

EXAM UNDER ANESTHESIA (EUA), SPECULUM EXAM, VAGINOSCOPY

VAGINAL SAMPLES

COMPLETING THE EXAMINATION

OFFICE EVALUATION OF THE ADOLESCENT

OBTAINING THE HISTORY

GYNECOLOGIC EXAMINATION

DIAGNOSTIC TESTS

PAPANICOLAOU TEST

WET PREPARATIONS

OTHER COMMERCIAL TESTS FOR BACTERIAL VAGINOSIS

pH

TESTS FOR NEISSERIA GONORRHOEAE AND CHLAMYDIA TRACHOMATIS

OTHER TESTS

PROGESTERONE WITHDRAWAL TEST

PREGNANCY TESTS

BONE AGE

IMAGING TECHNIQUES

DETECTION OF OVULATION

TRACKING MENSTRUAL CYCLES

2 Interviewing the Adolescent: Strategies That Promote Communication and Foster Resilience

TALKING WITH TEENS: ADOPTING A STRENGTH-BASED APPROACH

STRATEGIES THAT OPTIMIZE COMMUNICATION WITH ADOLESCENTS

EMBRACING A PATIENT-CENTERED APPROACH TO COMMUNICATION

PAYING ATTENTION TO BODY LANGUAGE

“SETTING THE STAGE” FOR HONEST COMMUNICATION

“SETTING THE STAGE” WITH THE TEEN’S PARENTS

TRAUMA-INFORMED PRACTICE

A NEW APPROACH TO THE SOCIAL HISTORY

STRATEGIES FOR STRENGTH-BASED RISK BEHAVIOR COUNSELING

AVOIDING SHAME: LISTENING FOR THE POSITIVE

STATING THE CONCERN IN CONTEXT OF THE TEEN’S LIFE AND ASKING FOR PERMISSION TO ADDRESS IT

ADJUSTING THE COUNSELING APPROACH BASED ON STAGE OF CHANGE

TAKING COGNITIVE DEVELOPMENT INTO ACCOUNT

GUIDING INSTEAD OF LECTURING

TEACHING NEGOTIATION SKILLS

TAKING SOCIAL CONTEXT INTO ACCOUNT

INCORPORATING MOTIVATIONAL INTERVIEWING TECHNIQUES

NURTURING A RESILIENT YOUTH

3 Embryology of the Reproductive Tract

4 The Physiology of Puberty

HORMONAL CHANGES AT PUBERTY

STAGES OF BREAST AND PUBIC HAIR DEVELOPMENT

GROWTH PATTERNS

BONE DEVELOPMENT AND ACCRETION

MENARCHE

HORMONE LEVELS IN NORMAL OVULATORY CYCLES

CLINICAL APPLICATIONS

5 Adolescent Sexuality and Sex Education

ADOLESCENT SEXUAL BEHAVIORS

SEXUAL BEHAVIOR

NONCONSENSUAL SEXUAL EXPERIENCES

SEXUALLY TRANSMITTED INFECTIONS

PREGNANCY AND BIRTHS AMONG ADOLESCENTS

DRUGS AND ALCOHOL

ISSUES FOR LGBT ADOLESCENTS

THE NEED FOR LGBT-INCLUSIVE SEX EDUCATION

ADOLESCENT RELATIONSHIPS

SEX EDUCATION

SUPPORT FOR SEX EDUCATION IN SCHOOLS

EFFECTIVE PREGNANCY AND HIV/AIDS PREVENTION PROGRAMS

DIGITAL APPROACHES TO SEX EDUCATION

YOUNG PEOPLE WITH DISABILITIES

PEER INFLUENCES

THE ROLE OF PARENTS

THE MEDIA

A GLOBAL PERSPECTIVE

ROLE OF THE HEALTH CARE PROVIDER

6 Education and Support of the Child and Adolescent With Gynecologic Issues

OFFICE EDUCATION

GYNECOLOGIC EDUCATIONAL CONSIDERATIONS

PAP TEST AND COLPOSCOPY EDUCATION

MAYER-ROKITANSKY-KüSTER-HAUSER SYNDROME

ENDOMETRIOSIS

GYNECOLOGIC SURGICAL CONSIDERATIONS

PREOPERATIVE EDUCATION

PERIOPERATIVE EDUCATION

POSTOPERATIVE EDUCATION AND SUPPORT

SPECIFIC GYNECOLOGIC SURGICAL CONSIDERATIONS

CONCLUSION

7 Training in Pediatric and Adolescent Gynecology

TRAINING EXPERIENCES IN PEDIATRIC AND ADOLESCENT GYNECOLOGY

RESIDENCY TRAINING

FELLOWSHIP TRAINING

ADVANCED TRAINING

TEACHING TOOLS IN PEDIATRIC AND ADOLESCENT GYNECOLOGY

TEXTBOOKS AND CURRICULA

INTERACTIVE AND ELECTRONIC LEARNING PLATFORMS FOR PAG TEACHING

SIMULATION FOR TEACHING PAG

SUMMARY

8 Patient Safety and Quality Improvement in Office Gynecology

FACTORS CONTRIBUTING TO PATIENT HARM IN THE OFFICE

MEDICAL MALPRACTICE AND AMBULATORY CARE

MEDICAL MALPRACTICE AND OFFICE GYNECOLOGY

STRATEGIES FOR PREVENTING ERRORS AND IMPROVING OFFICE-BASED PRACTICE

CULTIVATE A CULTURE OF SAFETY

ASSESS SAFETY CULTURE

PROVIDE LEADERSHIP FOR PATIENT SAFETY IN THE OFFICE

FOSTER A LEARNING ENVIRONMENT

ADDRESS COMMON PITFALLS IN OFFICE PRACTICE

QUALITY IMPROVEMENT AND METRICS IN OFFICE-BASED CARE

CREATE A SAFE ENVIRONMENT FOR OFFICE-BASED SURGERIES

CONCLUSION

9 Legal Issues in Pediatric and Adolescent Gynecology

NATURE AND SOURCES OF LAW

CONSENT TO MEDICAL CARE

CONFIDENTIALITY OF PATIENT INFORMATION

SEXUAL ABUSE

CONTRACEPTION

STERILIZATION

ABORTION

SEXUALLY TRANSMITTED INFECTIONS

HIV AND AIDS

SUMMARY

PART 2 Evaluation and Management of Developmental and Structural Gynecologic Issues

10 Ambiguous Genitalia in the Newborn and Disorders of Sex Development

TERMINOLOGY

APPROACH TO THE CHILD WITH DSD

GENDER DESIGNATION

ASSESSMENT OF THE NEONATE

HISTORY

PHYSICAL EXAMINATION

LABORATORY AND RADIOGRAPHIC TESTS

REVIEW OF EMBRYOGENESIS

TESTICULAR DIFFERENTIATION

PHENOTYPIC SEX

DIFFERENTIAL DIAGNOSIS OF AMBIGUOUS GENITALIA IN THE NEWBORN

SEX CHROMOSOME DISORDERS OF SEXUAL DEVELOPMENT

XX DISORDERS OF SEXUAL DEVELOPMENT

CONGENITAL ADRENAL HYPERPLASIA

MATERNAL OR FETOPLACENTAL ANDROGENS

46,XX TESTICULAR DSD

XY DISORDERS OF SEXUAL DEVELOPMENT

DISORDERS OF GONADAL (TESTICULAR) DEVELOPMENT

DISORDERS IN ANDROGEN SYNTHESIS OR ACTION

MALFORMATION SYNDROMES

HYPOSPADIAS AND CRYPTORCHIDISM

11 Structural Abnormalities of the Female Reproductive Tract

ABNORMALITIES OF THE FEMALE REPRODUCTIVE TRACT

EXTERNAL GENITALIA

DISORDERS OF MESONEPHRIC REMNANTS

INTROITAL ABNORMALITIES

ANOMALIES OF THE UTERUS, FALLOPIAN TUBE, CERVIX, AND VAGINA

DIAGNOSIS AND TREATMENT OF SPECIFIC ANOMALIES OF THE FEMALE GENITAL TRACT

IMPERFORATE HYMEN

MICROPERFORATE/SEPTATE/COMPLEX HYMEN

ANOMALIES OF THE VAGINA

TRANSVERSE VAGINAL SEPTUM

DISTAL VAGINAL ATRESIA/AGENESIS OF THE LOWER VAGINA/SEGMENTAL VAGINAL AGENESIS

VAGINAL AGENESIS (MÜLLERIAN APLASIA)

McINDOE VAGINOPLASTY

WILLIAMS PROCEDURE

BOWEL VAGINAS

DAVYDOV, AMNION, WHARTON, AND SHEARES PROCEDURE

VECCHIETTI AND MODIFIED VECCHIETTI PROCEDURES

OUTCOMES OF NONSURGICAL AND SURGICAL NEOVAGINA

CERVICAL ANOMALIES

CERVICAL ATRESIA/HYPOGENESIS

UTERINE ANOMALIES

TRUE DUPLICATION AND INCOMPLETE FUSION OF THE MÜLLERIAN DUCTS

LONGITUDINAL VAGINAL SEPTUM

DISORDERS OF THE UTERUS

UTERINE SEPTUM (ARCUATE/NORMAL, PARTIAL SEPTUM, COMPLETE SEPTUM)

FERTILITY OPTIONS AND PREGNANCY OUTCOME IN WOMEN WITH MüLLERIAN DUCT ANOMALIES

12 Pediatric Urology

PRESENTING SYMPTOMS: EVALUATION AND DIFFERENTIAL DIAGNOSIS

DYSURIA

HEMATURIA

INCONTINENCE

RENAL COLIC

FLANK PAIN AND FEVER

PERINEAL MASS

INCIDENTAL: CONGENITAL ANOMALIES OF THE URINARY TRACT

SUMMARY OF ESSENTIAL EVALUATION MODALITIES

ULTRASOUND

CYSTOGRAPHY—RADIOGRAPHIC, ULTRASOUND, AND RADIONUCLIDE

INTRAVENOUS PYELOGRAM

RADIONUCLIDE RENAL SCANS: DMSA AND MAG-3

COMPUTED TOMOGRAPHY

MAGNETIC RESONANCE IMAGING/MAGNETIC RESONANCE UROGRAPHY

URODYNAMICS

MAJOR CONDITIONS

DYSFUNCTIONAL VOIDING

NOCTURNAL ENURESIS

URINARY OBSTRUCTION: URETEROPELVIC JUNCTION OBSTRUCTION AND URETEROVESICAL JUNCTION OBSTRUCTION

URINARY TRACT INFECTION

REFLUX

STONE

ECTOPIC URETER AND URETEROCELE

RENAL MASSES

PELVIC TUMORS

EXSTROPHY AND EPISPADIAS

URETHRAL PROLAPSE

ACKNOWLEDGMENT

13 Multidisciplinary Management of Complex Urologic, General Surgical, and Gynecologic Anomalies

SUBSYMPHYSEAL EPISPADIAS

BLADDER EXSTROPHY

CLOACAL ANOMALY

AMBIGUOUS GENITALIA

XX DISORDERS OF SEX DEVELOPMENT (FORMERLY ADRENOGENITAL SYNDROMES)

HIGH AGENESIS OF THE LOWER VAGINA

CONCLUSION

PART 3 Vulvar and Vaginal Disorders

14 Vulvovaginal Problems in the Prepubertal Child

VULVOVAGINITIS

NORMAL VAGINAL FLORA

ETIOLOGY OF VULVOVAGINITIS

OBTAINING THE HISTORY

PHYSICAL EXAMINATION

LABORATORY TESTS

TREATMENT

LICHEN SCLEROSUS

VAGINAL BLEEDING

TREATMENT OF NONTRAUMATIC ETIOLOGIES OF VAGINAL BLEEDING

INTERLABIAL MASSES

CLITORAL LESIONS

LABIAL ADHESIONS

MISCELLANEOUS ENTITIES

15 Vulvar Dermatology

IS IT VULVOVAGINITIS OR A VULVAR DERMATOSIS?

THE ETIOLOGY OF PEDIATRIC VULVAR COMPLAINTS—GYNECOLOGIC OR DERMATOLOGIC, OR WHO SEES WHAT?

SPECIAL CHARACTERISTICS OF VULVAR SKIN

FACTORS PREDISPOSING TO VULVAR DERMATOSES IN CHILDREN AND ADOLESCENTS

OFFICE APPROACH TO VULVAR DERMATOLOGY

THERAPEUTICS

GENERAL MEASURES

MEDICATIONS

VULVAR SKIN BIOPSY

OTHER USEFUL DERMATOLOGIC PROCEDURES

CURETTAGE

LIQUID NITROGEN CRYOTHERAPY

NORMAL VULVAR FINDINGS THAT MAY BE CONFUSED WITH SKIN DISEASE

SEBACEOUS GLANDS

VESTIBULAR PAPILLOMATOSIS

VULVAR DERMATOSES IN INFANCY

IRRITANT DIAPER DERMATITIS

CANDIDAL DIAPER DERMATITIS

JACQUET EROSIVE DERMATITIS

GRANULOMA GLUTEALE INFANTUM

SEBORRHEIC DERMATITIS

LANGERHANS CELL HISTIOCYTOSIS

ACRODERMATITIS ENTEROPATHICA

HEMANGIOMA OF INFANCY

INFANTILE PERIANAL PYRAMIDAL PROTRUSION

VULVAR DISEASE IN OLDER CHILDREN AND ADOLESCENTS

PIGMENTARY DISORDERS

INFLAMMATORY DISEASES

VULVAR ULCERS

INFECTIOUS DISEASES

BACTERIAL

VIRAL

FUNGAL

AUTOIMMUNE BLISTERING DISEASES

BENIGN SOFT TISSUE TUMORS

VULVAR MANIFESTATIONS OF SYSTEMIC DISEASE

SPECIAL TOPICS

CHRONIC VULVAR PRURITUS AND VULVAR PAIN (VULVODYNIA)

PUBIC HAIR REMOVAL

GENITAL PIERCING

16 Genital Trauma

PATIENT ASSESSMENT

EXAMINATION IN A CHILD OR ADOLESCENT

DIAGNOSIS

ETIOLOGY OF ACCIDENTAL GENITAL INJURIES

TREATMENT

MEDICAL CARE OF SEXUALLY ABUSED CHILDREN AND TEENS

MANAGEMENT OF GENITAL INJURIES

SPECIAL CONSIDERATIONS

FOLLOW-UP

SUMMARY

17 Vulvovaginal Complaints in the Adolescent

VAGINAL DISCHARGE

PHYSIOLOGIC DISCHARGE

TRICHOMONAL VAGINITIS

TREATMENT

CANDIDA VAGINITIS

BACTERIAL VAGINOSIS

DESQUAMATIVE INFLAMMATORY VAGINITIS (DIV)

VAGINITIS SECONDARY TO A FOREIGN BODY

GENITAL HERPES SIMPLEX VIRUS (HSV)

MOLLUSCUM CONTAGIOSUM

PEDICULOSIS PUBIS (CRABS)

SCABIES

PINWORMS

VULVAR DISORDERS

VULVAR TRAUMA

VULVAR ULCERS

NEVI

STEVENS–JOHNSON SYNDROME/TOXIC EPIDERMAL NECROLYSIS

TOXIC SHOCK SYNDROME

DYSURIA

LABIAL HYPERTROPHY

PART 4 Vulvar and Vaginal Disorders

18 Sexually Transmitted Infections: Chlamydia, Gonorrhea, Pelvic Inflammatory Disease, Syphilis, and Mycoplasma genitalium

CHLAMYDIA TRACHOMATIS INFECTION

SCREENING

DISEASE MANIFESTATIONS AND SEQUELAE

RECURRENT INFECTIONS

DIAGNOSIS

REACTIVE ARTHRITIS

TREATMENT

INFECTIONS IN NEONATES AND PREPUBERTAL CHILDREN

NEISSERIA GONORRHOEAE INFECTIONS

SCREENING

DIAGNOSIS

UROGENITAL GONOCOCCAL INFECTION

TREATMENT OF ASYMPTOMATIC INFECTIONS, CONTACTS, URETHRITIS, AND CERVICITIS

GONOCOCCAL PHARYNGITIS

GONOCOCCAL PROCTITIS

MANAGEMENT

GONOCOCCAL CONJUNCTIVITIS

DISSEMINATED GONOCOCCAL INFECTION

GONOCOCCAL INFECTIONS IN NEONATES AND PREPUBERTAL CHILDREN

PELVIC INFLAMMATORY DISEASE

DIAGNOSIS

OUTPATIENT THERAPY FOR ACUTE PELVIC INFLAMMATORY DISEASE

INPATIENT (PARENTERAL) THERAPY FOR ACUTE PID

TREATMENT OF TUBO-OVARIAN ABSCESS

FOLLOW-UP

SPECIAL POPULATIONS

CONSEQUENCES OF ACUTE PELVIC INFLAMMATORY DISEASE

SYPHILIS

STAGES OF SYPHILIS

DIAGNOSIS OF SYPHILIS

TREATMENT

SYPHILIS AND HIV INFECTION

SYPHILIS IN PREGNANCY

OTHER MANAGEMENT CONSIDERATIONS

Mycoplasma Genitalium

PREVALENCE

PRESENTATION AND DIAGNOSIS

TREATMENT

19 Diagnosis, Management, and Prevention of Human Immunodeficiency Virus in Young Women

EPIDEMIOLOGY

ESTIMATES OF HIV/AIDS INCIDENCE AND PREVALENCE IN YOUTH/YOUNG WOMEN

HIV SEROPREVALENCE AND BEHAVIORAL RISK FACTOR STUDIES

ASSESSMENT

HIV SCREENING, TESTING, AND RISK ASSESSMENT

SCREENING AND TESTING FOR HIV: BARRIERS AND FACILITATORS

DIAGNOSING HIV

PRENATAL SCREENING FOR HIV

PREVENTION OF MATERNAL TO CHILD TRANSMISSION

ACUTE RETROVIRAL SYNDROME

DIAGNOSING AIDS

TREATMENT AND INITIAL CARE

CARE ENTRY: STAGING INFECTION—BASELINE EVALUATION FOR YOUNG WOMEN WITH HIV

HIGHLY ACTIVE ANTIRETROVIRAL THERAPY AND TREATMENT INITIATION

PREVENTION

PrEP

nPEP

REPRODUCTIVE AND GYNECOLOGIC CONDITIONS IMPACTED BY HIV

GYNECOLOGIC CONDITIONS IMPACTED BY HIV

REPRODUCTIVE HEALTH ISSUES

CONTRACEPTION

FOLLOW-UP AND PRIMARY CARE

PSYCHOSOCIAL CARE AND SUPPORT AND PROMOTING HEALTHY TRANSITIONS

20 Human Papillomavirus Infection and Cervical Cancer Screening and Prevention in Adolescents

BACKGROUND

PREVENTION OF HUMAN PAPILLOMAVIRUS INFECTION AND SEQUELAE

PRIMARY PREVENTION

SECONDARY PREVENTION

BIOLOGY OF HUMAN PAPILLOMAVIRUS INFECTION

VIROLOGY AND GENETICS

HUMAN PAPILLOMAVIRUS TYPING

NATURAL HISTORY AND EPIDEMIOLOGY OF HUMAN PAPILLOMAVIRUS INFECTION

HUMAN PAPILLOMAVIRUS IN CHILDREN

HUMAN PAPILLOMAVIRUS INFECTION IN ADOLESCENTS

CONDYLOMATA ACUMINATA

ABNORMAL CYTOLOGY

EVALUATION AND MANAGEMENT OF HUMAN PAPILLOMAVIRUS INFECTION IN CHILDREN

RISK FACTORS FOR HUMAN PAPILLOMAVIRUS IN ADOLESCENTS

EVALUATION OF HUMAN PAPILLOMA VIRUS IN ADOLESCENTS

CERVICAL CANCER SCREENING AND MANAGEMENT IN ADOLESCENTS

HISTORY OF CERVICAL CANCER SCREENING GUIDELINES

UPDATED GUIDELINES FOR CERVICAL CANCER SCREENING IN YOUNG WOMEN

SPECIAL POPULATIONS

LESBIAN AND BISEXUAL WOMEN

WOMEN WITH DISABILITIES

HIV POSITIVE OR OTHERWISE IMMUNOCOMPROMISED FEMALES

UNDERSERVED AND INCARCERATED ADOLESCENT FEMALES

MÜLLERIAN ANOMALIES

ADOLESCENTS WITH AN INTRAUTERINE SYSTEM (IUS) IN PLACE

TRANSGENDER YOUTH

MANAGEMENT OF HUMAN PAPILLOMAVIRUS IN ADOLESCENTS

CONDYLOMATA

CURRENT GUIDELINES FOR MANAGEMENT OF ABNORMAL CERVICAL CYTOLOGY IN YOUNG WOMEN

COLPOSCOPIC EXAMINATION

HUMAN PAPILLOMAVIRUS VACCINATION

DEVELOPMENT AND LICENSING OF HUMAN PAPILLOMAVIRUS VACCINES

EFFICACY AND EFFECTIVENESS OF HUMAN PAPILLOMAVIRUS VACCINES

SAFETY OF THE VACCINES

VACCINE ADMINISTRATION IN CLINICAL SETTINGS

ISSUES TO CONSIDER IN IMPLEMENTATION OF HUMAN PAPILLOMAVIRUS VACCINATION PROGRAMS

CONCLUSIONS

ACKNOWLEDGEMENT

PART 5 Pubertal and Menstrual Disorders

21 Precocious Puberty

PREMATURE THELARCHE

PATIENT ASSESSMENT

TREATMENT AND FOLLOW-UP

PREMATURE ADRENARCHE

PATIENT ASSESSMENT

TREATMENT AND FOLLOW-UP

PRECOCIOUS PUBERTY

CENTRAL PRECOCIOUS PUBERTY

CAUSES OF CENTRAL PRECOCIOUS PUBERTY

IDIOPATHIC

CEREBRAL DISORDERS

SECONDARY CENTRAL PRECOCIOUS PUBERTY

PERIPHERAL (GONADOTROPIN-INDEPENDENT) PRECOCIOUS PUBERTY

OVARIAN TUMORS

ADRENAL DISORDERS

AUTONOMOUS FOLLICULAR OVARIAN CYSTS

IATROGENIC DISORDERS

PRIMARY HYPOTHYROIDISM

PATIENT ASSESSMENT

TREATMENT AND FOLLOW-UP

CONTRASEXUAL PRECOCIOUS PUBERTY (ANDROGEN EXCESS WITH VIRILIZATION)

PATIENT ASSESSMENT

TREATMENT AND FOLLOW-UP

PREMATURE MENARCHE

22 Delayed Puberty

EVALUATION—HISTORY AND PHYSICAL EXAMINATION

EVALUATION—LABORATORY TESTING AND IMAGING STUDIES

HYPOGONADOTROPIC HYPOGONADISM

An aparitie	2019
Autor	HUGH S TAYLOR, LUBNA PAL AND EMRE SELL
Dimensiuni	22.1 x 4.8 x 28.2 cm
Editura	LWW
Format	Hardcover
ISBN	9781451189766
Limba	Engleza
Nr pag	1487