Neurology Evidence: The Practice Changing Studies

Description:

Synthesizing the vast body of literature available in neurology into one accessible, clinically relevant volume, Neurology Evidence: The Practice-Changing Studies is an invaluable resource for students, residents, and fellows, as well as neurologists at all levels of experience. Featuring the top 100 papers that have had the most significant impact on changing clinical practice, this unique title analyzes the strengths and weaknesses of both seminal and less-noticed studies. Readable commentary is provided for each study by both a senior and junior neurologist in each subspecialty.

Table of Contents:

Section 1: ISCHEMIC STROKE

1. Intravenous tPA for Acute Ischemic Stroke

2. Aspirin for Secondary Stroke Prevention

3. Mechanical Thrombectomy for Large Vessel Occlusion

4. Harm from Stenting of Symptomatic Intracranial Arterial Stenoses

5. Warfarin for Atrial Fibrillation

6. Novel Oral Anticoagulants for Stroke Prevention in Nonvalvular Atrial Fibrillation

7. Intense Low-Density Lipoprotein Cholesterol Reduction for Stroke Prevention

8. Marginal Benefit from Device Closure of Patent Foramen Ovale

9. Early Decompressive Surgery in Malignant Infarction of the Middle Cerebral Artery

10. Carotid Endarterectomy for Stroke Prevention in Internal Carotid Artery Stenosis

11. Carotid Artery Stenting vs. Carotid Endarterectomy For Symptomatic and Asymptomatic Carotid Artery Stenosis

12. Warfarin and Aspirin in Patients with Heart Failure and Sinus Rhythm

13. Short-Term Dual Antiplatelet Therapy for Stroke Prevention after TIA or Minor Stroke

14. Aspirin Over Warfarin for Symptomatic Intracranial Stenosis

15. Lack of Benefit from Long-Term Dual Antiplatelet Therapy for Secondary Stroke Prevention

16. Fluoxetine for Motor Recovery after Acute Ischemic Stroke

17. Carotid Endarterectomy for Asymptomatic Carotid Artery Stenosis

18. Extended Monitoring for Paroxysmal Atrial Fibrillation

19. The National Institutes of Health Stroke Scale

Section 2: CEREBRAL HEMORRHAGE

20. Blood Pressure Regulation in Parenchymal Intracerebral Hemorrhage

21. Early Surgery for Spontaneous Intracerebral Hemorrhage and Hydrocephalus

22. Avoidance of Long-Term Anticoagulation for Atrial Fibrillation after Intracerebral Hemorrhage

23. Nimodipine for Prevention of Delayed Neurologic Injury after Subarachnoid Hemorrhage

24. Inferiority of Surgical Resection to Medical Management of Unruptured AVM

25. Prognostication for Intracerebral Hemorrhage

26. Acute Endovascular Treatment for Ruptured Subarachnoid Hemorrhage

27. Neurosurgical Clipping vs. Endovascular Coiling of Ruptured Intracranial Aneurysms

28. Withdrawal of Support in Intracerebral Hemorrhage because of Predicted Poor Prognosis May Lead to Self-Fulfilling Prophecy

29. rtPA for Intraventricular Hemorrhage

30. Grading of Ruptured Subarachnoid Hemorrhages

Section 3: TRAUMATIC BRAIN INJURY

31. Glasgow Coma Scale

32. Albumin vs. Saline for Resuscitation after Traumatic Brain Injury

33. Decompressive Craniectomy in Traumatic Brain Injury

34. Antiepileptic Drugs after Traumatic Brain Injury

35. Intracranial Pressure Monitoring in Traumatic Brain Injury

36. Amantadine for Recovery of Consciousness after Traumatic Brain Injury

37. Functional Imaging in Vegetative States

38. Corticosteroids for Traumatic Brain Injury

39. Corticosteroids in Acute Spinal Cord Injury

Section 4: NEUROLOGIC INTENSIVE CARE

40. Midline Shift and Level of Consciousness

41. Use of Hyperosmolar Therapy for Cerebral Edema

42. Hyperventilation for Acute Intracranial Pressure Elevation

43. Temperature Management for Cardiac Arrest in Adults

44. Early Mobilization in the Intensive Care Unit

Section 5: NEUROINFECTIOUS DISEASES

45. Glucocorticoids for Bacterial Meningitis in Adults

46. Acyclovir for Herpes Simplex Encephalitis

47. Polymerase Chain Reaction Testing for Herpes Simplex Encephalitis

48. Antifungal Therapy for Cryptococcal Meningitis

49. Guidelines for Treatment of Lyme Disease in the Nervous System

Section 6: NEURO-ONCOLOGY

50. Temozolomide for Glioblastoma

51. Surgery for Brain Metastases

52. Chemotherapy for Low-Grade Glioma

53. NovoTTF for Newly Diagnosed Glioblastoma

54. Bevacizumab for Recurrent Glioblastoma

55. Methotrexate for Primary CNS Lymphoma

Section 7: NEUROMUSCULAR

56. Acute Treatment for Guillain-Barre Syndrome

57. Alternate Day Prednisone in Myasthenia Gravis

58. IVIg vs. Prednisone for Chronic Inflammatory Demyelinating Polyneuropathy

59. Glucocorticoid Steroids for Duchenne Muscular Dystrophy

60. Riluzole in Amyotrophic Lateral Sclerosis

61. Thymectomy in Myasthenia Gravis

Section 8: MOVEMENT DISORDERS

62. L-Dopa for Parkinson’s Disease

63. Deep Brain Stimulation for Parkinson’s Disease

64. Deep Brain Stimulation for Dystonia

65. L-Dopa vs. MAO-B Inhibitors in Parkinson’s Disease

66. Propranolol Treatment for Essential Tremor

67. Rasagiline in Parkinson’s Disease

68. Botulinum a Toxin for Dystonia

Section 9: MULTIPLE SCLEROSIS

69. Progressive Multifocal Leukoencephalopathy after Treatment with Natalizumab

70. Glucocorticoids for Optic Neuritis: The Optic Neuritis Treatment Trial

71. Neuromyelitis Optica Antibody in the Diagnosis of Neuromyelitis Optica

72. Correlation Between MRI Findings and Disability in Multiple Sclerosis

73. The Association of Vitamin D Levels and Multiple Sclerosis

74. Rate of Pregnancy-Related Relapse in Multiple Sclerosis

Section 10: AUTOIMMUNE NEUROLOGY

75. EULAR Recommendations for Treatment of Primary CNS Vasculitis

76. NMDA-ab Receptor Encephalitis with Ovarian Teratoma

77. Identification of Sjogren’s Syndrome Associated Ganglionopathy

78. IVIG for Stiff Person Syndrome

Section 11: EPILEPSY

79. Lorazepam for Treatment of Status Epilepticus

80. Magnesium for the Prevention of Eclampsia

81. Antiepileptic Drug Treatment after a First Unprovoked Seizure

82. Intravenous vs. Intramuscular Benzodiazepines for Status Epilepticus

83. Continuous EEG Monitoring for Evaluation of Nonconvulsive Status Epilepticus

Section 12: HEADACHE AND PAIN

84. Sumatriptan for Migraine

85. Topiramate for Migraine Prevention

86. Duloxetine for Chemo-Induced Painful Neuropathy

87. Pregabalin for Neuropathic Pain

88. Amitriptyline Prophylaxis for Headache

89. Divalproex for Migraine Prophylaxis

Section 13: COGNITIVE NEUROLOGY

90. Donepezil for Alzheimer’s Disease

91. Memantine in Addition to Donepezil for Alzheimer’s Disease

92. Rivastigmine for Dementia with Lewy Bodies

93. Melatonin for REM Sleep Behavior Disorder

94. Agitation in Dementia

Section 14: PEDIATRIC NEUROLOGY

95. Treatment of Infantile Spasms

96. Pharmaco vs. Behavioral Therapy for ADHD

97. Ketogenic Diet for the Treatment of Childhood Epilepsy

98. Hypothermia for Neonates with Hypoxic-Ischemic Encephalopathy

99. Febrile Seizures

100. When to Stop Antiepileptic Drugs in Children with Epilepsy

Index