Leprosy and Buruli Ulcer: A Practical Guide

Description:

A highly disabling infectious disease in developing countries, leprosy, or Hansen’s disease, is caused by Mycobacterium leprae, and is still very relevant for the human community due to its transmissible nature, variable presentation and composite clinical picture. Early identification of leprosy and Buruli ulcer (also caused by a Mycobacterium, M. ulcerans) is critical to prevent spreading and patient disability and to establish appropriate therapy. This richly illustrated, completely revised second edition of Leprosy and Buruli Ulcer describes the characteristic signs of both these diseases, and contents include abnormalities of the skin, nerves, eyes, hands, feet, testes and bone. It also presents the latest diagnostic tools to identify and quantify organ damage to enable readers to recognize and treat this composite systemic disorder, which can represent a true medical emergency if affecting eyes, nerves, and kidneys. Further, it includes additional chapters on leprosy in childhood, prophylaxis and vaccines. For both leprosy and Buruli ulcer, this handy guide helps practitioners and nursing personnel to spot the different clinical manifestations, make a prompt diagnosis and apply effective treatment of both these diseases.

Table of Contents:

Part I. Leprosy: General Section

1. History and Phylogeography of Leprosy

2. Microbiology of Mycobacterium leprae

3. Genetics of Leprosy

4. Host Response to Mycobacterium leprae

5. Pathogenesis of Leprosy

6. Classification of Leprosy

Part II. Leprosy: Patient’s Examination

7. Leprosy Patient History

8. Laboratory Investigations in Leprosy

Part III. Skin

9. Physical Examination in Leprosy: Skin

10. Clinical Features of Leprosy

11. Lucio–Latapí Leprosy

12. Histopathology of the Skin in Leprosy

13. Differential Diagnosis of Leprosy: Skin

Part IV. Leprosy and Nerves

14. Peripheral Nerves in Leprosy

15. The Leprosy Neuropathy

16. Primary Neural Leprosy

17. Chronic Neuropathic Pain in Leprosy

18. Electrodiagnostic Studies in Leprosy

19. Imaging in Leprosy

20. Differential Diagnosis of Leprosy: Nerves

Part V. Reactions in Leprosy

21. Reactions in Leprosy

22. Lucio’s Phenomenon in Leprosy

Part VI. Leprosy: Systemic Involvement

23. Ocular Involvement in Leprosy

24. Otolaryngological Manifestations of Leprosy

25. Other Organs Involved in Leprosy

Part VII. Patient’s Management in Leprosy

26. Diagnostic Work-Up of Leprosy

27. Drugs in Leprosy

28. Treatment and Prophylaxis of Leprosy

29. Prognosis of Leprosy

30. Neurolysis in Leprosy

31. Prevention of Disability and Ulcer Care in Leprosy

32. Surgical and Social Rehabilitation in Leprosy

Part VIII. Leprosy and Community

33. Leprosy in Pregnancy

34. Leprosy in Childhood

35. Leprosy and HIV/AIDS Co-infection

36. Epidemiology of Leprosy

37. Leprosy Control

38. The Leprosy Mailing List

Part IX. Buruli Ulcer: General Section

39. History and Geographic Distribution of Buruli Ulcer

40. Microbiology of Mycobacterium Ulcerans

Part X. Buruli Ulcer: Patient’s Examination

41. Laboratory Investigations in Buruli Ulcer

42. Clinical Features of Buruli Ulcer

43. Differential Diagnosis of Buruli Ulcer

Part XI. Buruli Ulcer: Patient’s Management

44. Diagnostic Work-up of Buruli Ulcer

45. Treatment of Buruli Ulcer

46. Rehabilitation in Buruli Ulcer

Part XII. Buruli Ulcer and Community

47. Epidemiology of Buruli Ulcer

48. Buruli Ulcer Control

Back Matter