Colon Cancer Diagnosis and Therapy Vol. 3

Description:

Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide.  Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the third of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.

Table of Contents:

Role of chemokines in colorectal cancer

Extracellular vesicles in colorectal cancer growth, metastasis, diagnosis and therapy

Epigenetic regulation of colorectal cancer (CRC): Mechanism and Therapeutic Interventions

Mechanistic exploration and therapeutic management of colon cancer metastasis.

Chemoresistance in colon malignancies: Molecular mechanism and strategies to overcome

Targeting pathogenic inflammation for therapeutic intervention against colon cancer

Role of tumor associated macrophages in colon cancer progression and its therapeutic targeting

Therapeutic intervention of signaling pathways in colorectal cancer

Advances in chemoradiotherapy for treatment of colon cancer

Cytotoxic and chemopreventive activity of polyphenols and their derivatives in colon cancer

Prevention and management of colon cancer by nutritional intervention

Development of RNA based medicine for colorectal cancer: current scenario

Role of food additives and intestinal microflora in colorectal cancer

Probiotics in colon cancer: a therapeutic approach

Bacterial cancer therapy: promising role in the treatment of colon cancer

Antineoplastic effects of curcumin against colorectal cancer: application and mechanisms

Cyanobacterial secondary metabolite: A potential drug candidates against colon cancer

Clinical Significance of Genetic Variants in Colon Cancer