Atlas of Hepatocellular Carcinoma Pathology

Over 550 high-quality gross and microscopic photos

Provides quick references for daily practice

Challenging cases highlight common diagnostic dilemmas

About this book

This atlas is designed to be a user-friendly bench-side reference for pathology trainees and general pathologists in handling and interpreting specimens of hepatocellular carcinoma. It provides over 550 high-quality gross and microscopic photos focusing on hepatocellular carcinoma and its mimickers, and demonstrating a full range of various histological variants of hepatocellular carcinoma. Introductory text in each chapter summarises salient clinical associations, pathological features, and molecular alterations of different variants of hepatocellular carcinoma. Differentiation between hepatocellular carcinoma and its mimickers is illustrated through various case studies.

The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.

Table of contents (17 chapters)

Front Matter

Pages i-xi

Introduction

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 1-2

Precursor Lesions of Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 3-25

Gross Morphology of Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 27-30

General Histopathological Features of Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 31-46

Fibrolamellar Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 47-49

Steatohepatitic Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 51-55

Clear Cell Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 57-59

Macrotrabecular-Massive Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 61-64

Scirrhous Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 65-67

Lymphocyte-Rich Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 69-75

Other Uncommon Histological Variants of Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 77-83

Hepatocellular Carcinoma with Cytokeratin 19 Expression

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 85-88

Combined Hepatocellular-Cholangiocarcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 89-96

Post-treatment Changes of Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 97-101

Ancillary Tests for Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 103-144

Tumour Staging for Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 145-153

Differential Diagnoses of Hepatocellular Carcinoma

Haeryoung Kim, Wei-Qiang Leow, Regina Lo, Paulo Giovanni L. Mendoza, Anthony Wing-Hung Chan

Pages 155-193