Atlas of Genitourinary Pathology: A Pattern Based Approach

Closely mirroring the daily sign-out process, Atlas of Genitourinary Pathology: A Pattern Based Approach is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical presentation and locating hidden clues in the slides. Useful as a daily “scope-side guide,” it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.

• More than 1,200 high-quality photomicrographs capture the subtle morphologic spectrum of both biopsy and resection specimens of the prostate, bladder, kidney, testis, and the male genital tract. Each image is captioned with key diagnostic considerations and includes call-outs showing subtle features and diagnostic clues.
• Practical tools throughout the text include:
  • Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options
  • Discussions of how and when to incorporate immunohistochemical, and if necessary, molecular tools
  • Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports.
  • Photographs of select gross specimens, and numerous histologic correlates
  • Brief reviews of normal histology that provide contrast to succeeding patterns
  • “Pearls and Pitfalls” and “Near Misses” sections with lessons from real life sign-out experience            
  • “Frequently Asked Questions” sections that discuss common diagnostic dilemmas   
  • “Sample Note” sections that offer a template of how to synthesize complicated or especially challenging topics
  • Comprehensive quiz provides experience with high-yield, board-style teaching topics

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Table of Contents:

1.    Cover

2.    Title Page

3.    Copyright

4.    Dedication

5.    Preface

6.    Acknowledgements

7.    Contents

8.    Chapter 1: Prostate

9.    The Unremarkable and Nonneoplastic Prostate

10.  Anatomy and Histology

11.  The Prostate “Capsule” and Boundaries

12.  The Prostatic Glandular Epithelium

13.  Simple Atrophy

14.  Prostatic Nodular Hyperplasia

15.  Benign Seminal Vesicle and Ejaculatory Duct Tissue

16.  Ganglia and Paraganglia

17.  Immunohistochemistry

18.  Artifacts and Contaminants in Prostate Specimens

19.  Small Round Gland Epithelial Lesions

20.  Benign Mimics of Cancer

21.  Prostatic Acinar Adenocarcinoma

22.  Basal Cell Carcinoma (Small Gland Pattern)

23.  Poorly Formed Gland Lesions and Mimics

24.  Paraganglion

25.  Xanthoma

26.  Poorly Formed Gland Prostatic Adenocarcinoma

27.  Cancer With Treatment Effect

28.  Large/Complex Gland Epithelial Lesions

29.  Benign Mimics of “Large Gland” Lesions

30.  High-Grade Prostatic Intraepithelial Neoplasia

31.  Malignant Large Gland and Gland-Like Lesions

32.  Pleomorphic Tumors

33.  Tumors With a Neuroendocrine Appearance

34.  Small Blue Cell Pattern Tumors

35.  Small Cell Carcinoma

36.  Small Cell–Like Change in Prostatic Neoplasms

37.  Poorly Differentiated Prostatic Adenocarcinoma

38.  Other Small Blue Cell Pattern Tumors

39.  Stromal Lesions

40.  Inflammatory Processes

41.  Nonneoplastic Processes

42.  Neoplastic Processes

43.  Tumors of the Seminal Vesicle

44.  Seminal Vesicle Carcinoma

45.  Mixed Epithelial and Stromal Tumor

46.  Mesenchymal Tumors of the Seminal Vesicle

47.  Reporting Elements for Prostatic Specimens

48.  Biopsy Reporting

49.  Radical Prostatectomy Reporting and Staging

50.  Near Misses

51.  Adenosis (Atypical Adenomatous Hyperplasia)

52.  Ductal Prostatic Adenocarcinoma Involving Urethra

53.  Paraganglion Tissue

54.  Urothelial Carcinoma vs High-Grade Prostatic Adenocarcinoma

55.  Prostatic Adenocarcinoma With Treatment Effect

56.  Chapter 2: Bladder

57.  The Unremarkable and Nonneoplastic Bladder

58.  Anatomy and Histology

59.  The Near-Normal Bladder

60.  Biopsy and Transurethral Resection of Bladder Tumors

61.  Surface Lesions of the Bladder

62.  Flat Lesions of the Bladder

63.  Papillary Lesions of the Bladder—Urothelial

64.  Papillary Lesions of the Bladder—Nonurothelial

65.  Deep Lesions of the Bladder

66.  Invasive Urothelial Carcinoma

67.  Neoplastic Deep Lesions of the Bladder—Glandular Pattern

68.  Other Patterns of Neoplastic Deep Lesions of the Bladder

69.  Neoplastic Deep Lesions of the Bladder—Spindle Pattern

70.  Nonneoplastic Deep Lesions of the Bladder—Glandular Pattern

71.  Nonneoplastic Deep Lesions of the Bladder—Spindle Pattern

72.  Near Misses

73.  Inverted Papilloma

74.  Metastatic Colorectal Adenocarcinoma

75.  Mullerianosis

76.  Melanoma

77.  Chapter 3: Kidney

78.  The Unremarkable and Nonneoplastic Kidney

79.  Anatomy and Histology

80.  Nonneoplastic Renal Disease

81.  Tumors

82.  Renal Cancer General

83.  Clear/Pale Cell Pattern

84.  Papillary Pattern

85.  Oncocytic/Eosinophilic Cell Pattern

86.  Tubular/Solid Patterns

87.  Cystic Lesions

88.  Infiltrative Pattern

89.  Spindle Cell Tumors

90.  Tumors With Spindle Cell and Epithelial Components

91.  Renal Cancer Staging

92.  Renal Cancer Grading

93.  Inflammatory Pattern and Nonneoplastic Pseudotumors

94.  Lymphoma

95.  Xanthogranulomatous Pyelonephritis

96.  Malakoplakia

97.  Near Misses

98.  Hemangioma Versus Renal Cell Carcinoma

99.  Clear Cell Versus Clear Cell Papillary Renal Cell Carcinoma

100.               Subtle Vein Invasion in Renal Cancer

101.               Unclassified Oncocytic Tumor

102.               Chapter 4: Testis

103.               The Unremarkable Testis

104.               Anatomy and Histology

105.               The Near Normal Testis

106.               Nonneoplastic Testis and Epididymis

107.               Testis Biopsy for Infertility

108.               Infectious/Inflammatory

109.               Torsion and Vasculitis

110.               Testicular Tumors

111.               Monomorphic

112.               Pleomorphic

113.               Organoid

114.               Spindle Cell Pattern

115.               Serum Tumor Markers in Testicular Cancer

116.               Immunohistochemistry in Testicular Tumors

117.               Testicular Cancer Reporting and Staging

118.               Near Misses

119.               Testicular Infarct

120.               Regressed Germ Cell Tumor

121.               Identifying Lymphovascular Invasion in Germ Cell Tumor

122.               Chapter 5: Paratestis and External Genitalia

123.               Paratestis

124.               The Unremarkable Paratestis

125.               “Celes” and Cystic Lesions

126.               Glandular Lesions

127.               Papillary Lesions

128.               Adipocytic Lesions

129.               Spindle Pattern

130.               Scrotum and Penis

131.               The Unremarkable External Genitalia

132.               Inflammatory Pattern

133.               Spindle Pattern

134.               Papillary/Exophytic Pattern

135.               Squamous Epithelial In Situ Processes

136.               Well-Differentiated/Keratinizing Pattern

137.               Basaloid/Undifferentiated Pattern

138.               Metastatic Disease

139.               Near Misses

140.               Self-Assessment Questions

141.               Index