Anticoagulation Therapy

Description:

This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.

Table of contents:

1. Introduction

Part I. Anticoagulants

2. Warfarin

3. Unfractionated Heparin and Low-Molecular-Weight Heparin

4. Parenteral Anticoagulants: Direct Thrombin Inhibitors and Pentasaccharides

5. Direct Oral Anticoagulants

6. Anticoagulation Reversal

7. Transitioning Between Anticoagulants

Part II. Clinical Applications of Anticoagulant Therapy

8. The Anticoagulation Clinic

9. Perioperative Management of Anticoagulants

10. Acute Coronary Syndromes

11. Antithrombotic Therapy for Patients with Atrial Fibrillation

12. Anticoagulant Strategies for Electrophysiology Procedures

13. Anticoagulation for Cardiac Prosthetic Devices: Prosthetic Heart Valves, Left Ventricular Assist Devices, and Septal Closure Devices

14. Anticoagulation in Venous Thromboembolism

15. Thrombophilic States

16. Thrombophilia Testing

17. Heparin-Induced Thrombocytopenia

18. Anticoagulation Therapy in Pregnant Patients

19. Anticoagulation in the Elderly

20. Anticoagulation in the Patient with Cancer