Textbook of Diabetes and Pregnancy (Series in Maternal-Fetal Medicine)

Written by a cadre of experts, this new edition provides a comprehensive, authoritative, and international view of gestational diabetes mellitus and will be invaluable to maternal-fetal medicine specialists, diabetologists, neonatologists, and a growing number of gynecologists and general physicians concerned with the management of noncommunicable diseases in pregnancy. Offers a comprehensive and authoritative guide to all aspects of the subject internationally Presents an invaluable resource for all working in diabetes, maternal-fetal medicine, and obstetrics Shows the latest developments in research in genomics and in practice with the digital clinic.

Table of Contents:

In Memoriam: Oded Langer† by Yariv Yogev

Honoring Lois Jovanovič (1947–2018) by Alejandra de Leiva-Pérez and Alberto de Leiva-Hidalgo

Preface

List of Contributors

1 Prologue: Maternal Medicine Meets Fetal Medicine: Merging the Legacies and Hypotheses

2 History of Diabetic Pregnancy

3 Epidemiology of Gestational Diabetes Mellitus

4 The Great Obstetric Syndromes: The Roots of Disease

5 Metabolism in Normal and in Diabetic Pregnancy

6 Nutrient Delivery and Metabolism in the Fetus

7 Pathogenesis of Gestational Diabetes Mellitus

8 Autoimmunity in Gestational Diabetes Mellitus

9 The Placenta in Diabetic Pregnancy

10 Gestational Diabetes Mellitus: The Consequences of Not Treating

11 Implications of Diabetic Pregnancy: The Offspring

12 Short-Term Implications: The Neonate

13 Implications of Diabetic Pregnancy: The Mother

14 Gestational Diabetes Mellitus, Obesity and Pregnancy Outcomes

15 Hypertensive Disorders and Diabetic Pregnancy

16 Fetal Congenital Malformations in Diabetic Pregnancy

17 Post-Implantation Diabetic Embryopathy

18 Congenital Malformations in Diabetic Pregnancy: Prevalence and Types

19 Reproduction and Its Impact on Health and Disease

20 Prediction and Prevention of Gestational Diabetes Mellitus

21 Inositols and Prevention of Gestational Diabetes Mellitus

22 The Multiomics Approach to Diabetes in Pregnancy

23 The Role of Bariatric Surgery in Obese Women Planning Pregnancy

24 The Role of Glucagon-Like Peptide-1 (GLP-1) in Women with Obesity Planning Pregnancy

25 Diagnosis of Gestational Diabetes Mellitus

26 Glucose Intolerance in Pregnancy: A Window to Mother and Offspring Future Cardio-Metabolic Risk

27 Ideal Weight Gain in Pregnancy with Diabetes

28 Glycemic Goals in Diabetic Pregnancy and Defining “Good Control”: Maternal and Fetal Perspective

29 Medical Nutritional Therapy for Gestational Diabetes Mellitus

30 Insulin Therapy in Pregnancy

31 Use of Non-Insulin Antihyperglycemic Drugs in Relation to Pregnancy

32 Continuous Subcutaneous Insulin Infusion and Continuous Glucose Monitoring in Pregnancy

33 Periconceptional Assessment in Diabetic Women Planning Pregnancy

34 Early Pregnancy Loss and Perinatal Mortality

35 Fetal Surveillance in Diabetic Pregnancies

36 Timing and Mode of Delivery in Diabetic Pregnancy

37 Management of the Macrosomic Fetus: Can Fetal Macrosomia Be Predicted and Prevented?

38 Gestational Diabetes in Twin Pregnancies

39 Fetal Growth Restriction in Diabetic Pregnancies

40 Diabetes, Obesity, Hypertension, and Preterm Birth

41 Diabetic Retinopathy

42 Diabetic Kidney Disease

43 Diabetic Ketoacidosis

44 Thyroid In Pregnancy

45 Gestational Diabetes in Lower- and Middle-Income Countries

46 Managing Diabetic Pregnancy in China

47 Links between Maternal Health and Noncommunicable Diseases

48 Diabetes, Pregnancy, and the Developmental Origins of Health and Disease

49 Postpartum Management: Mother and Offspring

50 Non-Invasive Glucose Monitoring

51 Closed-Loop Insulin Delivery in Type 1 Diabetes Pregnancy

52 Epilogue: Maternal Fetal Medicine Meets Femtech while Digitalizing Pregnancy Management: Present and Future

Index