Subarachnoid Hemorrhage

Description:

This book highlights the latest developments in acute and delayed neurovascular injury studies including delayed cerebral vasospasm, early brain injury, micro-circulation compromise, spreading cortical depolarization, neuroinflammation, and long-term cognitive dysfunctions after subarachnoid hemorrhage. About 32 chapters cover original presentations from the 14th international conference on neurovascular events after subarachnoid hemorrhage, held in Los Angeles in October 2017. Neurosurgeons, neurologists, and neuro-ICU practitioners discuss clinical observations, new pilot treatments, clinical trials, academic and industrial interactions, including surgical and endovascular approaches, brain injury monitoring, new developments in brain imaging, ICU management, early brain injury scales and management, counter cortical depolarization management and anti-inflammation management. In addition, animal models used to study acute and delayed neurovascular events, the basic mechanisms of vascular, neuronal, and CSF physiology, new experimental treatment strategies, new frontiers in the treatment of neurovascular injuries, and new research directions are discussed. 

Table of Contents:

Vasospasm: A Personal Odyssey

History of Vasospasm Research in Japan: Commemoration of Professor Tomio Ohta

Heparin Treatment in Aneurysmal Subarachnoid Hemorrhage: A Review of Human Studies

Subarachnoid Hemorrhage-Related Epilepsy

Part I. Basic Science Section

Cell Culture Model to Study Cerebral Aneurysm Biology

Rat Model of Intracranial Aneurysm: Variations, Usefulness, and Limitations of the Hashimoto Model

Possible Involvement of Caspase-Independent Pathway in Neuronal Death After Subarachnoid Hemorrhage in Mice

Nox2 and Nox4 Participate in ROS-Induced Neuronal Apoptosis and Brain Injury During Ischemia-Reperfusion in Rats

Link Between Receptors That Engage in Developing Vasospasm After Subarachnoid Hemorrhage in Mice

Aquaporin4 Knockout Aggravates Early Brain Injury Following Subarachnoid Hemorrhage Through Impairment of the Glymphatic System in Rat Brain

The Role of Galectin-3 in Subarachnoid Hemorrhage: A Preliminary Study

17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats

TAK-242, Toll-Like Receptor 4 Antagonist, Attenuates Brain Edema in Subarachnoid Hemorrhage Mice

Subarachnoid Hemorrhage Pattern Predicts Acute Cerebral Blood Flow Response in the Rat

Toll-Like Receptor 4 and Tenascin-C Signaling in Cerebral Vasospasm and Brain Injuries After Subarachnoid Hemorrhage

Spreading Depolarization during the Acute Stage of Experimental Subarachnoid Hemorrhage in Mice

The PERK Pathway Plays a Neuroprotective Role During the Early Phase of Secondary Brain Injury Induced by Experimental Intracerebral Hemorrhage

The Time Course of Cognitive Deficits in Experimental Subarachnoid Hemorrhage

Endovascular Ultraviolet Laser-Facilitated Reversal of Vasospasm Induced by Subarachnoid Hemorrhage in Canines

Part II. Clinical Science Section

Role of Bedside Multimodality Monitoring in the Detection of Cerebral Vasospasm Following Subarachnoid Hemorrhage

Development of a Delayed Cerebral Infarction Load Scoring System (DCI Score)

Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage

Transcranial Doppler Ultrasound, Perfusion Computerized Tomography, and Cerebral Angiography Identify Different Pathological Entities and Supplement Each Other in the Diagnosis of Delayed Cerebral Ischemia

Role of Computational Fluid Dynamics for Predicting Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage: Study Protocol for a Multicenter Prospective Study

Thromboelastometry as a Comprehensive Assessment of Hypercoagulation After Aneurysmal Subarachnoid Hemorrhage: A Case Report and Literature Review

The Treatment of a Ruptured Anterior Communicating Artery (ACoA) Aneurysm with Coiling and Flow Disruptor (WEB-Device) and Management of Symptomatic Post-Interventional Delayed Vasospasm: A Case Report

Treating Patients with Frontal Neurocognitive Deficits After SAH and Stroke

Intra-arterial Administration of Verapamil for the Prevention and Treatment of Cerebral Angiospasm

Cerebral Arterial Compliance in Polytraumazed Patients with Cerebral Vasospasm

The Сerebrovascular Time Constant in Patients with Head Injury and Posttraumatic Cerebral Vasospasm

Current Open Surgical Indications for Revascularization in Cerebral Ischemia

The Role of Transcranial Doppler in Cerebral Vasospasm: A Literature Review

Back Matter