Pharmacology in Veterinary Anesthesia and Analgesia

DESCRIPTION

Pharmacology in Veterinary Anesthesia and Analgesia

A concise yet comprehensive and usable pharmacological resource for veterinary practitioners

In Pharmacology in Veterinary Anesthesia and Analgesia, a team of distinguished veterinary practitioners delivers a singular and comprehensive text dedicated to anesthetic drug pharmacology and drug interactions related specifically to anesthetic drugs in a veterinary setting. This concise, easily navigable reference combines information scattered throughout the academic literature and covers mechanisms of action of commonly used drugs in commonly encountered species, drug interactions, and clinical uses of anesthetic drugs.

The volume explores drug metabolism, the effects of various drugs on organ systems, risks of adverse effects, as well as the impact of anesthesia on drugs, and the effects of drugs on anesthesia.

Readers will also find:

·         A thorough introduction to pharmacokinetics, pharmacodynamics, and pharmacogenomics in veterinary anesthesia

·         Comprehensive explorations of veterinary regulatory concerns associated with anesthesia and analgesia for food animals

·         Practical discussions of alpha-2 agonists and antagonists, phenothiazines, butyrophenones, benzodiazepines, and opioid agonists and antagonists

·         Fulsome treatments of local anesthetics, non-steroidal anti-inflammatory drugs, inhalants, and induction drugs

Perfect for veterinary anesthesiologists and criticalists, internists, and surgeons, Pharmacology in Veterinary Anesthesia and Analgesia will also earn a place in the libraries of private practitioners and veterinary technicians performing anesthesia as well as researchers using veterinary species as a model.

TABLE OF CONTENTS

List of Contributors xxiv

Preface xxvi

1 Pharmacokinetics and Pharmacodynamics 1
Phillip Lerche and Jeffrey Lakritz

2 Pharmacogenetics in Veterinary Anesthesia and Analgesia 13
Jeffrey Lakritz

3 Veterinary Regulatory Concerns Associated with Anesthesia and Analgesia for Food Animals 31
Jeffrey Lakritz

4 α₂ Receptor Agonists and Antagonists 36
Lydia Love

5 Phenothiazines and Butyrophenones 55
John A.E. Hubbell

6 Benzodiazepines 60
Sébastien Hyacinthe Bauquier

7 Opioid Agonists and Antagonists 75
Phillip Lerche

8 Barbiturates 96
Bonnie L. Hay Kraus

9 Induction Drugs 106
Jennifer E. Carter

10 Inhalant Anesthetic Agents 123
Phillip Lerche and Linda Barter

11 Non-Steroidal Anti-Inflammatory Drugs 138
Craig Willette

12 Local Anesthetics 164
Turi K. Aarnes

13 Anticholinergics 171
Phillip Lerche

14 CNS Stimulants 177
Caitlin Tearney

15 Centrally Acting Muscle Relaxants 183
Bonnie L. Hay Kraus

16 Neuromuscular Blocking Agents 202
Manuel Martin-Flores and Daniel M. Sakai

17 Anticholinesterase Drugs and Reversal of Neuromuscular Blockade 215
Manuel Martin-Flores and Daniel M. Sakai

18 Sympathomimetics and Vasopressin 221
Phillip Lerche

19 Antihypertensives 236
Gianluca Bini

20 Antiarrhythmic Therapies and Calcium Channel Blockers 252
Lance C. Visser

21 Peripheral Vasodilators 266
Martin Kennedy

22 Behavior Drugs 283
Erin Wendt-Hornickle

23 Adjunctive Analgesic Pharmaceuticals 303
Reza Seddighi

24 Diuretics 315
Andrew Claude

25 Antiepileptics 324
Laurie Cook and Ashley C. Hechler

26 Antihistamines 339
S. Bryce Dooley

27 Anti-nausea, Antacid, and Prokinetic Drugs 350
Phillip Lerche

28 Insulin 357
Phillip Lerche

29 Electrolytes 362
Teresa A. Burns

30 IV Fluids 370
Anusha Balakrishnan

31 Blood and Blood Products 382
Julien Guillaumin

Index 392