Oxford Textbook of Heart Failure

The Oxford Textbook of Heart Failure 2e covers all aspects necessary to manage a patient with heart failure

The textbook provides an understanding of the basic mechanisms of heart failure through to an appreciation of the complexities of heart failure management and the remarkable improvements possible with good treatment

Full colour throughout, containing over 300 illustrations, and supported by detailed referencing from the huge evidence base that has developed over the last two decades

Extensive chapters on common co-morbidities of heart failure

Essential reading for consultant cardiologists and those in training, general physicians and those caring of the elderly, cardiothoracic surgeons, primary care doctors, pharmacists, and specialist nurses.

New to this Edition:

The new edition has been completely updated in line with new British and European Guidelines and contains new chapters on; Natriuretic Peptides and Novel Biomarkers in Heart Failure, The Future of Heart Failure, and Regenerative Therapies.

Table of Contents:

Section 1 What is heart failure?

1. What is heart failure?

2. Heart failure syndromes

Section 2 Epidemiology

3. The epidemiology of heart failure

Section 3 The aetiology of heart failure

4. The classical causes of heart failure

5. The genetics of heart failure

6. Metabolic disorders and heart failure

7. Heart failure in congenital heart disease

8. Infective and infiltrative causes of heart failure

9. Amyloidosis

10. Acute viral myocarditis

11. Iatrogenic heart failure

12. Peripartum cardiomyopathy

13. Takotsubo syndrome

Section 4 Pathophysiology of heart failure: cellular and molecular changes

14. The pathophysiology of heart failure

15. Cytokines and inflammatory markers

16. Calcium handling

17. Myocardial energetics

18. The failing cardiomyocyte

19. The interstitium and collagen in heart failure

20. Natriuretic peptides and novel biomarkers in heart failure

Section 5 Diagnosis of heart failure

21. Diagnosing heart failure

Section 6 Non-​invasive investigation

22. Basic investigation of heart failure

23. Echocardiography

24. Nuclear medicine in heart failure

25. Cardiovascular magnetic resonance in heart failure

26. Computed tomography imaging techniques

27. Cardiopulmonary exercise testing in chronic heart failure

Section 7 Invasive investigation

28. Invasive investigation

Section 8 Prognostication

29. Prognostication

Section 9 Co-​morbidities: the patient with heart failure and . . .

30. Heart failure with preserved ejection fraction: pathophysiology and treatment

31. Right heart failure

32. Anaemia and iron deficiency

33. Renal dysfunction

34. Chronic lung disease

35. Pulmonary hypertension

36. Diabetes mellitus

37. Valvular heart disease

38. Sleep-​disordered breathing

39. Arthritis

40. Arrhythmias

41. Pregnancy

42. Anxiety and depression

43. Cognitive impairment

Section 10 Treatment of acute heart failure

44. Inotropes, pressors, and vasodilators

45. Vasodilators

46. Ventilatory support

47. Therapeutic control of fluid balance in chronic heart failure

Section 11 Medical therapy for chronic heart failure

48. Angiotensin converting enzyme inhibitors and vasodilators

49. Angiotensin receptor blockers and angiotensin receptor–​neprilysin inhibitors

50. β-​Adrenoreceptor antagonists

51. Sodium–​glucose co-​transporter-​2 inhibitors

52. Mineralocorticoid receptor antagonists

53. Digoxin

54. Ivabradine

55. Antithrombotics

56. Problems with polypharmacy, alternative therapies and medication adherence

Section 12 Non-pharmological management

57. Cardiac rehabilitation and chronic heart failure

58. Non-​pharmacological management

Section 13 Device therapy for heart failure

59. Implantable cardioverter–​defibrillators

60. Cardiac resynchronization therapy

Section 14 Surgical therapy for heart failure

61. Heart transplantation

62. Revascularization, remodelling, and mitral valve surgery

63. Mechanical circulatory support

Section 15 Disease management

64. Multidisciplinary heart failure management programmes

65. End of life

66. Monitoring

67. Quality improvement in heart failure

Section 16 The future

68. Reparative therapies for the failing heart

69. The future