Neuromuscular Pathology Made Easy

Book Description:

The scope of Neuromuscular Pathology continuous to expand, as evidenced by the numerous multivolume and speciality texts published in recent years. This short textbook provides a complete overview of both clinical and histological aspects of common and rare neuromuscular diseases. The objective is twofold: to provide information about neuromuscular diseases in a simplified, integrated, and rapidly accessible format suited to those initially encountering the discipline, and also to provide a clear approach using simple pictures, tables and algorithms to illustrate histological features in muscle and nerve biopsy.

This volume is conveniently divided into three sections with a total of 30 chapters. The first section deals with basic principles of neuromuscular histology and physiology, processing technique, histochemistry, and laboratory management. The second and third sections deal with neuromuscular diseases that are summarized in a stepwise approach, complemented by algorithms and organized tables.

A simplified, integrated, and rapidly accessible format covering both common and rare neuromuscular diseases

Clear simple illustrations, organized tables and algorithms to aid the reader in finding an easy approach to accurate diagnosis

Practical tips to facilitate histopathological diagnosis.

Clinical scenarios discussing common neuromuscular conditions

Neurologists, neuropathologists, trainees and medical students involved in clinical neuroscience and pathology will find this guide of practical benefit in both education and practice.

Table of Contents:

Contributor List

Preface

Acknowledgment

Abbreviations

Part I: General

1. Muscle and Nerve Histology

2. Muscle and Nerve Fibers Classification

3. Clinical Neurophysiology

4. Neuromuscular Laboratory

5. Chemical Materials Used in the Lab

6. Biopsy Processing Protocol

7. Histochemistry Protocol

8. Genetic Basis Of Neuromuscular Disorders

9. Neuromuscular Final Report

Part II: Muscle

10. Initial Approach in Muscle Biopsy

11. Differential Diagnosis

12. Electron Microscopy

13. Classification of Myopathy

14. Approach to Neuromyopathy

15. Approach to Vacuolar Myopathy

16. Muscular Dystrophy Diseases

17. Inherited Myopathic Diseases

18. Non-Congenital Acquired Myopathies

19. Metabolic Myopathy

20. Inflammatory Myopathy

21. Chronic Denervation Myopathy

22. Axial Myopathy

23. Fasciitis

Part III: Nerve

24. Classification of Neuropathy

25. Diagnostic Approach in Nerve Biopsy

26. Axonal Neuropathy

27. Demyelinating Neuropathy

28. Cellular and Extracellular Abnormalities

29. Inflammatory Demyelination

30. Other Common Peripheral Neuropathies

Index