Navigating Melanoma Treatment Challenges. Next-Generation Strategies and Solutions

This book delves into the complexities of melanoma, offering an in-depth examination of the disease alongside the latest advancements in diagnosis and treatment. The initial chapter provides a comprehensive overview of melanoma, covering its fundamentals and introducing the latest technologies shaping the understanding of the disease. The book introduces advanced molecular diagnostics in identifying targetable mutations and tailoring therapies for personalized and effective melanoma treatment. Additionally, it investigates the role of artificial intelligence in melanoma diagnostics and the advancements in imaging technologies for the monitoring and assessment of melanoma. It also reviews novel, innovative immunotherapeutic approaches designed to enhance the body's immune response against melanoma cells. Further, the book delves into the development and application of targeted therapies and nanomedicine in treating melanoma. A dedicated chapter highlights the advantages of a multi-omics approach, integrating genomic, proteomic, and other omics data to achieve a holistic understanding of melanoma. Toward the end, the book examines the potential of combination therapies to improve treatment outcomes in melanoma. The book is a valuable source for cancer researchers, medical oncologists, and clinicians. 

Key Features

1. Provides a comprehensive overview of melanoma, covering its fundamentals and introducing the latest diagnostics and treatment strategies.
2. Investigates the transformative impact of artificial intelligence in melanoma diagnostics.
3. Focuses on immunotherapeutic advancements against melanoma.
4. Investigates the advancements in targeted therapies and nanomedicine.
5. Explores the synergy of genomics and proteomics in a comprehensive multi-omics approach to melanoma treatment.

Table of Contents

1.      Understanding Melanoma: From Basics to Cutting-Edge Insights

Zodwa Dlamini, Rodney Hull, Thulo Molefi, Richard E. Khanyile, Langanani Mbodi, Thifhelimbilu Emmanuel Luvhengo, and Ian C. Chikanza.

2.      Molecular Profiling in Melanoma: Precision Strategies for Targeted Therapies Meshack Bida, Thabiso Victor Miya, Dineo Disenyane, Michelle McCabe, Stylianos Makrogkikas, Georgios Lolas, and Zodwa Dlamini.

3.      Artificial Intelligence in Melanoma Diagnostics: Revolutionizing Detection and Diagnosis

Sikhumbuzo Z. Mbatha, Anil Madaree, Ravi Mehrotra, and Zodwa Dlamini.

4.      Immunotherapy Advancements: Harnessing the Immune System with Technological Precision

Botle Precious Damane, Thanyani Mulaudzi, Tania Maphoso, Dakalo Ramali, Cebo Beja, Talent Chipiti, Thabiso Victor Miya, Carmen Besliu, Jose Espinoza, Kamal S. Saini, and Zodwa Dlamini.

5.      Targeted Therapies and Nanomedicine: Precision at the Molecular Level Rahaba Marima, Olalekan Fadebi, Onyemaechi O. Azu, Innocent Edagha, Philemon Ubanako, Jyotsna Batra, and Zodwa Dlamini.

6.      Overcoming Resistance: Molecular Insights and Therapeutic Options

Benny Mosoane, Thabiso Victor Miya, Lesedi Nevondo, Paulina Czajka-Francuz, Paulo Nunes, Kamal S. Saini, and Zodwa Dlamini.

7.      Integrating Genomics and Proteomics: A Multi-Omics Approach to Melanoma Treatment

Rodney Hull, Thulo Molefi, Mark Jose, Kamal S. Saini, and Zodwa Dlamini.

8.      Next-Generation Imaging Technologies: Revolutionizing Melanoma Monitoring and Assessment

Lloyd Mabonga, Richard Khanyile, Edward Ngwenya, Ian C. Chikanza, and Zodwa Dlamini.

9.      Patient-Centric Technologies: Empowering Individuals in Melanoma Care Demetra Demetriou, Mahlatse Kgokolo, Ashokkumar Deenabandu, Sandra McGuigan, Kamal S. Saini, and Zodwa Dlamini.

10.  Unveiling Synergistic Future Horizons in Melanoma Combination Therapies

Talent Chipiti, Zukile Mbita, Elisa Marie Ledet, and Zodwa Dlamini.

11.  Collaborative Solutions for Future Challenges in Melanoma: A Technological Roadmap

Nkhensani Chauke-Malinga, Mohammed Alaouna, Thendo Netshiongolwe, Daniel Sambili, Thabiso Victor Miya, Richard C. Wu, and Zodwa Dlamini.

12.  Conclusion and Future Directions in Melanoma Treatment