Extracorporeal Membrane Oxygenation

• The first ECMO text to use the problem-based learning approach, focusing on education of the complex but lifesaving ECMO technology
• Comprehensively reviews technical, pharmacological, pathophysiological, neonatal, pediatric and adult aspects of ECMO
• includes a chapter on ECMO management in patients suffering with COVID-19, to cover the most urgent and pressing questions around ECMO during the ongoing pandemic.

”Extracorporeal Membrane Oxygenation : An Interdisciplinary Problem-Based Learning Approach” provides an overview of the latest techniques, management strategies and technology surrounding the clinical use of ECMO. This interdisciplinary book reviews the most common scenarios of ECMO in 62 chapters exploring the conditions and problems arising in ECMO practice.

Each chapter begins with a stem case, followed by open questions to encourage critical thinking and enable the reader to follow the management strategies of the authors, who are world leaders in the field. Followed by an evidence-based discussion, each chapter concludes with multiple-choice questions for self-assessment. This book is current in its knowledge of organ systems and management and keeps pace with new ECMO technology and surgical techniques coupled with current guidelines for management.

Starting with the history of ECMO to technical aspects, circuit biocompatibility and interaction with blood, drugs and flow physics, the volume continues into pediatric and adult sections, focussing on both respiratory and cardiovascular support, followed by a section on trauma. The volume then concludes with a section on neurologic complications and ethics, as well as rehabilitation and ambulation of ECMO patients. In addition, to reflect the current global health situation, this book also includes a chapter on ECMO management in patients suffering with COVID-19, to cover the most urgent and pressing questions around ECMO during the ongoing pandemic.

This is the first ECMO book on the market to utilise a problem-based learning approach and as such is an important unprecedented project on ECMO education.

Table of Contents

HISTORY OF ECMO
1 From the first ECMO patient into the future
TECHNICAL AND PROGRAMMATIC ASPECTS OF ECMO
2 Development and staffing of an ECMO service
3 ECMO configurations and cannulation in pediatric patients
4 ECMO configurations and cannulation in adult patients
5 The ECMO circuit and trouble shooting
6 Echocardiography in the management of ECMO patients
7 Airway management in ECMO patients
8 Acute renal failure and renal replacement therapy in ECMO patients
9 Ambulance ground transportation of ECMO patients
10 Fixed-wing and helicopter air transport of ECMO patients
11 Implications and experiences with long run ECMO
ECMO BLOOD INTERACTION
12 The unholy blood - biomaterial interaction in extracorporeal
13 Heparin anticoagulation for Trans-catheter Aortic Valve Implantation on ECMO
14 Bivalirudin for alternative anticoagulation in heparin induced thrombocytopenia during ECMO
15 Argatroban for anticoagulation in pediatric and adult ECMO
16 ECMO transfusion and coagulation management
PHARMACOLOGICAL CONSIDERATIONS FOR ECMO
17 Pharmacological considerations for analgesia and sedation of ECMO
18 Challenges of antimicrobial therapy in ECMO patients
19 Vasopressor and inotropic support in ECMO patients with refractory shock
ECMO IN NEONATAL AND PEDIATRIC RESPIRATORY DISEASE
20 ECMO for Meconium Aspiration Syndrome
21 ECMO for neonatal pulmonary hypertension and associated
22 ECMO in Congenital Diaphragmatic Hernia
23 Evidence and management of rare presentations in neonatal ECMO
24 ECMO for the pediatric patient with Status Asthmaticus
25 ECMO for pediatric pneumonia and sepsis
26 ECMO in pediatric lung transplantation
27 Weaning and decannulation of neonatal and pediatric respiratory ECMO support
ECMO IN NEONATAL AND PEDIATRIC CARDIAC DISEASE
28 ECMO in pediatric patients with univentricular circulation
29 ECMO in pediatric patients with congenital heart disease
30 Extracorporeal cardiopulmonary resuscitation in children
31 ECMO as a bridge to pediatric heart transplantation
32 Weaning and decannulation of pediatric cardiac ECMO
ECMO IN ADULT RESPIRATORY DISEASE
33 Veno-venous ECMO for Acute Respiratory Distress Syndrome
34 Extracorporeal CO2 removal to enhance protective ventilation in ARDS
35 ECMO in Middle Eastern Respiratory Syndrome (MERS-CoV)
36 ECMO in SARS-CoV-2 (COVID-19) patients
37 ECMO in pregnancy and the peripartum patient
38 ECMO in sickle cell disease and acute chest syndrome
39 ECMO for severe respiratory failure secondary to HIV infection
40 Bicaval dual lumen ECMO cannulation for lung transplantation
41 Weaning and liberation from V-V ECMO
ECMO IN ADULT CARDIAC DISEASE
42 ECMO support for adults with congenital heart disease
43 ECMO for myocardial infarction with cardiogenic shock
44 ECMO support for patients with myocarditis
45 Left ventricular venting strategies during ECMO support
46 ECMO support for patients with major aortic surgery or dissection
47 Mechanical support for post-cardiotomy right ventricular failure
48 ECMO for the complicated post-cardiotomy cardiac arrest
49 ECMO for accidental hypothermia and cardiorespiratory arrest
50 ECMO support for pulmonary embolism
51 Extracorporeal cardiopulmonary resuscitation in adults
52 Bridging from ECMO to durable left ventricular assist device
53 ECMO in the management of heart transplantation
54 Weaning and liberation from V-A ECMO
ECMO IN THE ADULT TRAUMA PATIENT
55 ECMO for hemorrhagic shock after blunt trauma
56 ECMO in patients with burn and smoke inhalation injury
REHABILITATION, NEUROLOGICAL AND ETHICAL ASPECTS OF ECMO
57 ECMO in the awake patient, early extubation and physical rehabilitation
58 Neurodevelopmental outcome after pediatric cardiac ECMO support
59 Neurologic complications in adult ECMO
60 Management of ECMO complicated by intracranial hemorrhage
61 Neurological monitoring and determination of brain death in ECMO
62 Ethical considerations for ECMO initiation and end-of-life care