Clinical Lymphatic Mapping in Gynecologic Cancers

Book Description

Lymphatic mapping techniques have proven to be useful to the early detection and safe treatment of endometrial and cervical cancers; however, the techniques have much of value to offer for breast cancer also and particularly for vulvar cancer, where there has been an explosion of interest and research. In the new edition of Clinical Lymphatic Mapping of Gynecologic Cancers, the techniques are fully explained, with consideration of the latest developments and technologies.

About the Author

Charles Levenback, MD is Professor and Deputy Chairman, Department of Gynecologic Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA, and formerly Chief Professionalism Officer. In 2017 he shared the Society of Gynecologic Oncology Innovation Award in recognition for his role in the development of sentinel lymph node biopsy in gynecologic oncology patients and his lead investigator role in multiple institutional and national clinical trials.

Ate G.J. van der Zee, MD, PhD is Professor of Gynaecological Oncology and Vice President of the Board of Directors, University Medical Center Groningen, The Netherlands. He leads a world-wide consortium (GROINSS-V-II), which performs landmark clinical studies in vulvar cancer, and shared the SGO Innovation Award in 2017.

Robert L. Coleman, MD, FACOG, FACS is Chief Scientific Officer, US Oncology Research, The US Oncology Network, McKesson Specialty Health, The Woodlands, TX, USA, and formerly Professor and Ann Rife Cox Chair of the Department of Gynecologic Oncology and Reproductive Medicine at the University of Texas MD Anderson Cancer Center and Executive Director of Cancer Network Research.

Table of Contents

List of contributors

Preface

1. The history of lymphatic mapping: a gynecologic perspective

Charles F. Levenback

2. Lymphatic anatomy: microanatomy and physiology

Erin K. Crane and Charles F. Levenback

3. Lymphatic anatomy: lymphatics of the vulva

Anca Chelariu-Raicu and Robert L. Coleman

4. Lymphatic anatomy: lymphatics of the cervix

Anca Chelariu-Raicu and Katherine C. Kurnit

5. Lymphatic anatomy: lymphatics of the uterus

Jennifer J. Mueller and Nadeem R. Abu-Rustum

6. Lymphatic anatomy: lymphatics of the ovary

Ate G.J. van der Zee

7. Lymphatic anatomy: lymphatics of the breast and axilla

James V. Fiorica

8. Modalities of detection of sentinel nodes in lymphatic mapping

Blanca Segarra, Nuria Agusti, and Pedro T. Ramirez

9. Ultrastaging of the sentinel node

Celien P.H. Vreuls, Ate G.J. van der Zee, and Paul J. van Diest

10. Sentinel lymph node biopsy of the vulva

Maaike Oonk and Ate G.J. van der Zee

11. Sentinel lymph node mapping in cervical cancer

David Cibula and Martina Borcinova

12. Sentinel lymph node mapping in breast cancer

Angelena Crown and Mary L. Gemignani

13. Sentinel lymph node biopsy of the endometrium

Jennifer J. Mueller and Nadeem R. Abu-Rustum

14. Impact of sentinel lymph node mapping on quality of life

Mariana Antonella Nigra, Pedro T. Ramirez, and Larissa Meyer

15. Radiation oncology considerations

Gwendolyn Joyce McGinnis and Anuja Jhingranviii

16. Special considerations

Michael Frumovitz

17. Clinical trial design

Scott Jordan and Brian M. Slomovitz

Index