Cibas and Ducatman's Cytology: Diagnostic Principles and Clinical Correlates

 

An ideal resource for both trainee and practicing pathologists, Cibas and Ducatman’s Cytology: Diagnostic Principles and Clinical Correlates, 6th Edition, is a practical, well-illustrated guide to the diagnostic interpretation of virtually any cytological specimen you may encounter. Concise yet comprehensive, this highly useful bench manual covers all organ systems and situations in which cytology is used, including gynecologic, non-gynecologic, and FNA samples, with an in-depth differential diagnosis discussion for all major entities. Now fully revised from cover to cover, it continues to focus on practical issues in diagnosis and the use of cytology in clinical care.

Uses easy-to-read, bulleted text to provide a quick review of key differential diagnoses, indications and methods, cytomorphologic features, clinical pearls, and tissue acquisition protocols for specific entities.

Incorporates key updates throughout, including new diagnostic biomarkers and their utility in differential diagnosis; the latest Bethesda System classifications and terminology; updated material on billing and coding; new techniques, new adjunct tests, and more.

Features hundreds of full-color illustrations that provide a real-life perspective of a full range of cytologic findings, as well as numerous summary tables and flow charts for quick reference.

Includes coverage of patient management in discussions of pertinent clinical features and emphasizes clinical correlation throughout.

Examines the role of immunohistochemistry, flow cytometry, and molecular biology in resolving difficulties in interpretation and diagnosis.

Provides an in-depth analysis of common diagnostic pitfalls to assist with daily sign-out and reporting.

Includes a video on how to perform fine needle aspiration biopsy, from the patient interview and precautions to demonstration of techniques.

Any additional digital ancillary content may publish up to 6 weeks following the publication date.

 

Table of Contents:

 

1 Cervical and Vaginal Cytology

The History of the Pap Test and Its Current Practice

Sampling and Preparation Methods

Automated Screening

Accuracy and Reproducibility

Diagnostic Terminology and Reporting Systems

The Bethesda System

The Normal Pap

Organisms and Infections

Benign and Reactive Changes

Vaginal Specimens in “DES Daughters”

Squamous Abnormalities

Glandular Abnormalities

Other Malignant Neoplasms

Endometrial Cells in Women ≥45 Years of Age

References

2 Respiratory Tract and Mediastinum

Normal Anatomy, Histology, and Cytology

Reporting Terminology

Sampling Techniques, Preparation Methods, and Accuracy

Benign Cellular Changes

Noncellular Elements and Specimen Contaminants

Infections

Nonneoplastic, Noninfectious Diseases

Benign Neoplasms and Neoplasms of Uncertain Behavior

Precursor Lesions of the Respiratory Tract

Lung Cancer

Metastatic Cancers to the Lung

Tumors of the Mediastinum

References

3 Urine and Bladder Washings

Indications

Specimen Collection

Sample Processing

Adequacy Criteria

Reporting Terminology

Accuracy

Normal Elements

Benign Lesions

Urothelial Neoplasms

Nonurothelial Neoplasms

Ancillary Techniques

Summary

References

4 Pleural, Pericardial, and Peritoneal Fluids

Specimen Collection, Preparation, and Reporting Terminology

Accuracy

Benign Elements

Nonneoplastic Conditions

Malignant Effusions

References

5 Peritoneal Washings

Specimen Collection, Preparation, and Reporting Terminology

Accuracy

The Normal Peritoneal Washing

Benign Conditions

Malignant Tumors

Monitoring Response to Treatment (“Second-Look Procedures”)

References

6 Cerebrospinal Fluid

Anatomy and Physiology

Obtaining and Preparing the Specimen

Reporting Terminology

Accuracy

Normal Elements

Abnormal Inflammatory Cells

Nonneoplastic Disorders

Neoplasms

References

7 Gastrointestinal Tract

Clinical Indications

Sample Collection and Processing

Accuracy

Overview of Morphologic Findings

Esophagus

Stomach

Duodenum

Colon

The Anal Pap Test

References

8 Fine Needle Aspiration Biopsy Technique and Specimen Handling

Materials and Supplies

Procedure for Performing FNA of a Palpable Mass

Preparing the Sample

Postprocedure Information for the Patient

Variations on Biopsy Technique

Ultrasound-Guided Techniques

Complications

Management of Adverse and Unexpected Events

Acknowledgments

References

Additional Resource

9 Breast

Specimen Types

Sample Preparation

Reporting Terminology

Evaluation of the Specimen

The Normal Breast

Benign Conditions

Papillary Neoplasms

Phyllodes Tumor

Breast Cancer

Uncommon Breast Tumors

Metastatic Tumors

References

10 Thyroid

Aspiration Technique and Slide Preparation

Terminology for Reporting Results

Accuracy

Evaluation of the Specimen

Benign

Follicular Neoplasm

Oncocytic Follicular Neoplasm

Malignant

Atypia of Undetermined Significance

Parathyroid Tumors

Molecular Testing

References

11 Salivary Gland

Rationale, Indications, and Technical Considerations

Classification

Diagnostic Overview

The Normal Aspirate

Nonneoplastic Conditions

Benign Neoplasms

Carcinomas of Salivary Gland Origin

Rare Malignant Neoplasms

Other Malignancies

Miscellaneous

Summary of Salivary Gland FNA

References

12 Lymph Nodes

Technical Aspects

Reporting Terminology and Accuracy

Ancillary Studies

Nonneoplastic Lesions

Neoplasms

References

13 Liver

Normal Liver

Infections

Benign Lesions

Malignant Tumors

Angiosarcoma

References

14 Pancreas and Biliary Tree

Indications

Sampling Techniques

Complications

Rapid On-Site Evaluation

Sample Preparation and Cyst Fluid Analysis

Accuracy and Limitations

Reporting Terminology

Normal Pancreas and Bile Duct

Pancreatitis and Reactive Changes

Pancreatic Intraepithelial Neoplasia

Ductal Adenocarcinoma

Ductal Adenocarcinoma Subtypes

Neuroendocrine Neoplasms

Acinar Cell Carcinoma

Solid Pseudopapillary Neoplasm

Pancreatoblastoma

Pancreatic Cysts

Secondary Pancreatic Neoplasms and Ectopic Splenic Tissue

References

15 Kidney and Adrenal Gland

The Kidney

Indications and Sampling Methods

Specimen Collection and Preparation

Reporting Terminology

Accuracy

Normal Elements

Benign Lesions

Renal Malignancies and Other Renal Tumors

The Adrenal Gland

Specimen Collection, Preparation, and Accuracy

References

16 Ovary

Obtaining the Specimen

Preparing the Specimen and Reporting Results

Accuracy

Benign Tumor-Like Lesions of the Ovary

Benign Surface Epithelial-Stromal Tumors

Malignant Surface Epithelial-Stromal Tumors

Clear Cell Carcinoma

Germ Cell Tumors

Sex Cord-Stromal Tumors

Uncommon Primary Ovarian Tumors

Metastatic Tumors

References

17 Soft Tissue

Specimen Collection and Preparation

Ancillary Studies

Reporting Terminology

Adipocytic and Lipogenic Neoplasms

Myxoid Neoplasms

Spindle Cell Neoplasms

Fibrohistiocytoid Neoplasms

Round Cell Neoplasms

Epithelioid Neoplasms

Pleomorphic Neoplasms

Dedifferentiated Sarcomas

Nonneoplastic Soft Tissue Lesions

References

18 Bone

Cartilaginous Tumors

Giant Cell-Rich Tumors

Osteogenic Tumors

Notochordal Tumors

Tumors of Other Lineages

Hematopoietic and Histiocytic Neoplasms

Nonneoplastic Bone Lesions

Metastatic Tumors to Bone

References

19 Laboratory Management

Agencies and Organizations

Regulations

Laboratory Personnel

Policy and Procedure Manuals

Workflow

Billing

Quality Control and Quality Assurance

Competency Assessment

Proficiency Testing

Performance Evaluation

Safety

References

Index

 

An aparitie	iun 2025
Autor	Edmund S. Cibas, Barbara S. Ducatman
Editura	Elsevier
Format	Hardcover
ISBN	9780323934343
Limba	Engleza
Nr pag	680