Asphyxia in Neonates

In severe asphyxia, lipid peroxidation occurs. Neonatal lipid concentration may indicate the severity of asphyxia and be a reason for needing cooling therapy. Asphyxia in Neonates describes the results of research into the impact oxygen deficits in neonates. The physiological consequences of asphyxiated newborn infants include changes in the pH of plasma and changes in lipid concentrations. These changes can result in apoptosis, loss of cell membrane integrity, and damage to the brain.

Features

• Reviews pathophysiology of asphyxia
• Describes the influence of asphyxia on lipids concentrations
• Summarizes the weight distribution of neonates with asphyxia based on lipid concentration
• Illustrates the use of lipids as an indicator of prognosis following asphyxia
• Provides guidance for lipids parameters in cooling therapy

Table of Contents:

Chapter 1

Perinatal asphyxia, hypoxia, ischemia and newborn

by  Miljana Z Jovandaric

Chapter 2

Pathophysiology of asphyxia in pregnancy

by Stefan Dugalic

Chapter 3

Causes of perinatal asphyxia

by Sandra Babic

Chapter 4

Multiorgan postasphyctic damage

by Miljana Z Jovandaric

Chapter 5

Pathogenesis of ischemia-reperfusion brain damage

by Miljana Z Jovandaric

Chapter 6

Lipid peroxidation during asphyxia

by Miljana Z Jovandaric

Chapter 7

Lipids - a predictive parameter of therapeutic hypothermia (cooling therapy) in asphyxiated newborns

by Miljana Z Jovandaric